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Assessment of an alternative to deep foundations in compressible clays： the structural cell foundation

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Frontiers of Structural and Civil Engineering 2018年第1期12卷 67-80页

作者： Sergio A. MARTINEZ-GALVAN miguel P. ROMO Institute of Engineering National University of Mexico Mexico City 04510 Mexico

The new type of deep foundation for buildings on saturated, compressible-low strength clayey soil deposits, branded structural cell essentially consists of a rigid concrete top slab, structurally connected to reinforced concrete peripheral walls （diaphragms） that enclose the natural soil. Accordingly, as the initial volume of the confined soft clays within the lateral stiff diaphragms will remain constant upon loading, the hollowed structural cell will be ＂transformed＂ into a very large cross-section pillar of unit weight slightly higher than that of the natural soft clayey soil. This type of foundation seems to be a highly competitive alternative to the friction pile-box foundations （widely used in Mexico City clays）, due to its economic and environmental advantages. Economies result, for example, from the absence of huge excavations hence sparing the need of earth retaining structures. Further savings result from appreciably smaller concrete volumes required for building the structural cell than the friction pile-box foundation; moreover, the construction time of the former is much shorter than that of the latter. Regarding the impact to the environment, less air contamination follows from the fact that both traffic jams and soil excavation lessen appreciably. Considering these facts and others regarding scheduling, it was decided to replace 48-friction pile-box foundations specified in the master plan project by this new type of foundation. The overall behavior of these cell foundations over a five-year period is fared from close visual observations and their leveling during the first three years after their construction.

关键词： deep foundations bearing capacity resistant moment structural cell 3D numerical modeling

Electrocardiograms changes in children with functional gastrointestinal disorders on low dose amitriptyline

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World Journal of Gastroenterology 2014年第32期20卷 11321-11325页

作者： Ashish Chogle miguel Saps Department of Pediatric Gastroenterology Hepatology and Nutrition Ann and Robert Lurie Children’s Hospital of Chicago Feinberg School of MedicineNorthwestern University Chicago IL 60611 United States

AIM: To study the effects of low dose amitriptyline on cardiac conduction in children.

关键词： Amitriptyline Electrocardiogram Children Abdominal pain related-functional gastrointestinal disorders

Involvement of substance P and the NK-1 receptor in pancreatic cancer

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World Journal of Gastroenterology 2014年第9期20卷 2321-2334页

作者： miguel Muoz Rafael Coveas Virgen del Rocío University Hospital Research Laboratory on Neuropeptides (IBIS) 41013 Seville Spain Institute of Neurosciences of Castilla y León (INCYL) Laboratory of Neuroanatomy of the Peptidergic Systems (Lab 14) University of Salamanca 37007 Salamanca Spain

Pancreatic cancer is the fourth leading cause of cancer related-death for both men and women and the 1-and5-year relative survival rates are 25%and 6%,***,it is urgent to investigate new antitumor drugs to improve the survival of pancreatic cancer *** peptide substance P(SP)has a widespread distribution throughout the *** binding to the neurokinin-1(NK-1)receptor,SP regulates biological functions related to cancer,such as tumor cell proliferation,neoangiogenesis,the migration of tumor cells for invasion,infiltration and metastasis,and it exerts an antiapoptotic effects on tumor *** is known that the SP/NK-1 receptor system is involved in pancreatic cancer progression:(1)pancreatic cancer cells and samples express NK-1 receptors;(2)the NK-1 receptor is overexpressed in pancreatic cancer cells in comparison with non-tumor cells;(3)nanomolar concentrations of SP induce pancreatic cancer cell proliferation;(4)NK-1 receptor antagonists inhibit pancreatic cell proliferation in a concentration-dependent manner,at a certain concentration,these antagonists inhibit100%of tumor cells;(5)this antitumor action is medi-ated through the NK-1 receptor,and tumor cells die by apoptosis;and(6)NK-1 receptor antagonists inhibit angiogenesis in pancreatic cancer *** these data suggest that the SP/NK-1 receptor system could play an important role in the development of pancreatic cancer;that the NK-1 receptor could be a new promising therapeutic target in pancreatic cancer,and that NK-1 receptor antagonists could improve the treatment of pancreatic cancer.

关键词： Pancreas Substance P Neurokinin-1 receptor antagonists Apoptosis Antitumor Angiogenesis Metastasis Pancreatic cancer

Magnetofection as a new tool to study microglia biology

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Neural Regeneration Research 2019年第5期14卷 767-768页

作者： Jose Luis Venero miguel Angel Burguillos Instituto de Biomedicina de Sevilla (IBiS)/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla and Departamento de Bioquímica y Biología Molecular Facultad de Farmacia Universidad de Sevilla Department of Biochemistry University of Cambridge

Microglia are the resident macrophages of the brain,originally described by Pio del Rio-Hortega(a student of Santiago Ramon y Cajal)in a series of studies in *** those pioneering studies,many others have followed to describe microglia as complex and multitasking cells with many diverse roles under physiological(*** key role in synapse pruning during development)or diseased *** exist as sentinels or surveyors of the environment that surround neurons,becoming reactive upon a wide array of stimuli and consequently developing an appropriate inflammatory *** fact,a neuroinflammatory response driven by microglia is found in virtually every disease process that occurs within the central nervous ***,a better understanding of the mechanisms governing the microglia response is the key to improving the outcome of neurodegenerative conditions.

关键词： Magnetofection new tool study microglia biology

Constructing Hopf Insulator from Geometric Perspective of Hopf Invariant

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Chinese Physics Letters 2024年第3期41卷 121-126页

作者：常治文郝维昌 miguel Bustamante 刘鑫 Institute of Theoretical Physics School of Physics and Optoelectronic EngineeringBeijing University of TechnologyBeijing 100124China School of Physics Beihang UniversityBeijing 100191China Complex and Adaptive Systems Laboratory School of Mathematics and StatisticsUniversity College DublinBelfield4DublinIreland

We propose a method to construct Hopf insulators based on the study of topological defects from the geometric perspective of Hopf invariant ***,we prove two types of topological defects naturally inhering in the inner... 详细信息

关键词： Hopf topological invariant

Green ionic metal-organic frameworks as nanocatalysts for CO_(2)fixation

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Nano Research 2025年第1期18卷 260-269页

作者： Nuria Martín miguel Maireles-Porcar Julián Sánchez Velandia Belén Altava Francisco G.Cirujano Eduardo García-Verdugo Departamento de Química Inorgánica y Orgánica Universidad Jaume IAv.Sos Baynats/nCastellóde la PlanaCastellón 12071Spain

Co,Ni,and Zn iso-reticular coordination polymers of 2,5-dihydroxyterphthalic acid(H_(2)dot)can be rapidly obtained under room temperature and aqueous conditions using either sodium or ammonium hydroxide as the bases to deprotonate the *** use of metal bromides and tetrabutylammonium hydroxide(TBAOH)as the base allows the green synthesis of ionic metal-organic frameworks(MOFs),characterized by X-ray diffraction(XRD),Fourier transform infrared(FTIR),scanning electron microscopy(SEM),thermo gravimetric analysis(TGA),H-nuclear magnetic resonance(NMR),elemental analysis,and X-ray photoelectron spectroscopy(XPS),and employed in the pressure,solvent,and additive-free CO_(2)fixation to epoxides by its cycloaddition to epichlorohydrin,exhibiting a cooperative behavior between the MOF and the ionic liquid formed within the framework,achieving TONs of the confined tetrabutylammonium bromide(TBABr)up to 700.

关键词： metal-organic frameworks(MOFs) ionic liquids heterogeneous catalysis CO_(2)conversion

Normozoospermic versus teratozoospermic domestic cats： differential testicular volume, sperm morphometry, and subpopulation structure during epididymal maturation

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Asian Journal of Andrology 2016年第6期18卷 871-878页

作者： miguel Angel Gutierrez-Reinoso Manuel Garcia-Herreros National Secretariat of Higher Education Science Technology and Innovation (SENESCYT) Quito Ecuador

Teratozoospermia （〈40% morphologically normal spermatozoa/ejaculate） is a frequent phenomenon in feline species. This research was carried out to study the possible differences in testicular volume, differential sperm morphometric traits, and potential differences regarding the sperm subpopulational structure during epididymal sperm maturation in teratozoospermic feline donors. Epididymal sperm samples were collected from the caput （R1）, corpus （R2）, and cauda （R3） epididymidis in two donor groups （N： normozoospermic; T： teratozoospermic）. Aliquots were assessed for concentration, viability, motility, and acrosomal integrity. Sperm morphometric descriptors from CASA-Morph analysis were analyzed by the Principal Component Analysis （PCA） and clustering analyses. Irrespective of the group analyzed, PCA revealed two Principal Components （PCs） for each epididymal region explaining more than the 93% of the variance. Surprisingly, the number of subpopulations remained constant in regions R1-R2-R3 irrespective of the donor group analyzed. However, the distribution of these subpopulations was found to be structurally different and strongly influenced by the epididymal region and the donor group. In conclusion, testicular morphometry and the sperm subpopulation structure were different in N and T donors. The alterations in subpopulations during epididymal maturation could be used as a potential clinical indicator of teratozoospermic individuals since an important influence of teratozoospermia on sperm subpopulation structure has been demonstrated.

关键词： epididymis feline sperm morphometry sperm subpopulations teratozoospermia testicular volume

Science Letters:Visual odometry for road vehicles—feasibility analysis

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第12期8卷 2017-2020页

作者： SOTELO miguel-angel GARCíA Roberto PARRA Ignacio FERNNDEZ David GAVILN miguel LVAREZ Sergio NARANJO José-eugenio Department of Electronics University of Alcalá Alcalá de Henares 28871 Spain Department of Informatics Industrial Automation Institute CSIC Madrid Spain

Estimating the global position of a road vehicle without using GPS is a challenge that many scientists look forward to solving in the near future. Normally, inertial and odometry sensors are used to complement GPS measures in an attempt to provide a means for maintaining vehicle odometry during GPS outage. Nonetheless, recent experiments have demonstrated that computer vision can also be used as a valuable source to provide what can be denoted as visual odometry. For this purpose, vehicle motion can be estimated using a non-linear, photogrametric approach based on RAndom SAmple Consensus (RANSAC). The results prove that the detection and selection of relevant feature points is a crucial factor in the global performance of the visual odometry algorithm. The key issues for further improvement are discussed in this letter.

关键词： 3D visual odometry Ego-motion estimation RAndom SAmple Consensus (RANSAC) Photogrametric approach

Exploring spatial relationships between stream channel features,water depths and flow velocities during flash floods using HEC-GeoRAS and Geographic Information Systems

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Journal of Geographical Sciences 2022年第4期32卷 757-782页

作者： miguel LEAL Eusébio REIS Pedro Pinto SANTOS Centre of Geographical Studies and Associated Laboratory TERRA Institute of Geography and Spatial PlanningUniversidade de Lisboa1600-276 LisbonPortugal Forest Research Centre and Associated Laboratory TERRA School of AgricultureUniversidade de LisboaTapada da Ajuda1349-017 LisbonPortugal

Water depths and flow velocities decisively influence the damage caused by flash *** Information System(GIS)is a powerful and useful tool,allowing the spatial analysis of results obtained by hydraulic modelling,namely from the HEC-RAS/HEC-GeoRAS *** GIS spatial analysis performed in this study seeks to explain and quantify the spatial relationships between the stream channel features and flow components during flash flood *** these relationships are generically known,there are few studies exploring this subject in different geographic contexts.A 1D hydraulic model was applied in a small watershed in Portugal,providing good results in the definition of floodable areas,water depths and longitudinal *** direct relationship was found between water depths and velocities in the floodable areas;however,negative strong correlations were found between the two flow components along the stream *** slope,channel and flood width,and roughness prove to be highly relevant on the longitudinal variations of water depths and velocities and on the location of maximum *** peak discharges and return periods(R;)can change the relationships between water depths and velocities at the same *** can be improved with more accurate elevation data for stream channels and floodplains.

关键词： flash floods water depth flow velocity geographic information systems(GIS) spatial analysis