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Rising costs and hospital admissions for hepatocellular carcinoma in Portugal(1993-2005)

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World Journal of Gastroenterology 2007年第10期13卷 1522-1527页

作者： Rui Tato Marinho José Giria miguel carneiro moura Liver Unit Department of Gastroenterology and HepatologyHospital de Santa MariaMedical School of LisbonPortugal Health Ministry of Portugal Epidemiology DivisionPortugal

AIM:To determine,for hepatocellular carcinoma(HCC),the patient demographic profile and costs of their admissions to the hospitals of the Portuguese National Health System from 1993 to ***:The National Registry(ICD-9CM,Inter-national Classification of Diseases,155.0)provided data from the 97 Hospitals in ***:We studied 7932 admissions that progres-sively rose from 292 in 1993 to 834 in 2005,having a male predominance of 78%(6130/7932).The global rate of hospital admissions for HCC rose from 3.1/105 in 1993 to 8.3/105 in *** average length of stay decreased from 17.5 ± 17.9 d in 1993 to 9.3 ± 10.4 d in 2005,P < *** average hospital mortality for HCC remained high over these years,22.3% in 1993 and 26.7% in ***,hospital costs(in Euros-€)rose in all variables studied:overall costs from €533 000 in 1993,to €4 629 000 in 2005,cost per day of stay from €105 in 1993,to €597 in 2005,average cost of each admission from €1828 in 1993,to €5550 in *** 2005,1.8%(15/834)of hospital admissions for HCC were related to liver transplant,and responsible for a cost of about €1.5 million,corresponding to one third of the overall costs for HCC admissions in that same ***:From 1993 to 2005 hospital admissions in Portugal for HCC *** costs for these admissions increased 9 times,with all variables related to cost analysis rising *** transplant,indicated in a small group of patients,showed a disproportionate increase in costs.

关键词： Hepatocellular carcinoma Hospitalization Length of stay Disease-related group cost analysis Hospital mortality

A Family of Methods of the DG-Morley Type for Polyharmonic Equations

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Advances in Applied Mathematics and Mechanics 2010年第3期2卷 303-332页

作者： Vitoriano Ruas Jose Henrique carneiro de Araujo UPMC-Univ.Paris 6 UMR7190 Inst.Jean Le Rond d’Alembert/CNRSParisFrance Visiting Professor at Graduate School of Computer ScienceUniversidade Federal FluminenseNiteròiRJBrazil department and Graduate School of Computer Science Universidade Federal FluminenseNiteròiRJBrazil

Discontinuous Galerkin methods as a solution technique of second order elliptic problems,have been increasingly exploited by several authors in the past ten *** is generally claimed the alledged attractive geometrical flexibility of these methods,although they involve considerable increase of computational effort,as compared to continuous *** work is aimed at proposing a combination of DGM and non-conforming finite element methods to solve elliptic m-harmonic equations in a bounded domain of R^(n),for n=2 or n=3,with m≥n+1,as a valid and reasonable alternative to classical finite elements,or even to boundary element methods.

关键词： Discontinuous Galerkin finite elements Hermite tetrahedrons Morley triangle non-conforming polyharmonic equations

Nanoengineering of solid oxide electrochemical cell technologies:An outlook

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Nano Research 2019年第9期12卷 2081-2092页

作者： Juliana carneiro Eranda Nikolla department of Chemical Engineering and Materials Science Wayne State UniversityDetroitMI48202USA

High temperature electrochemical energy conversion and storage technologies,such as solid oxide electrochemical cells (SOCs),have emerged as promising alternatives to mitigate environmental issues associated with combustion-based *** has been increased interest for nanoengineering SOC electrodes to enhance their efficiency.A major drive is the necessity for improved electrode kinetics via optimization of electrocatalysts for different key reactions in these *** this perspective,we discuss the requirements for SOC electrodes and nanoengineering strategies employed to achieve flexibility in electrode *** focus on identifying ways in which these nanoengineered materials foster advancements in the SOC electrocatalytic activity,selectivity,and *** conclude by proposing approaches that would lead to more stable electrocatalytic nanostructures with high degree of control over the number and nature of active *** nanostructures would enable systematic kinetic studies that could provide an in depth understanding of the reaction mechanisms that govern performance,leading to valuable knowledge for designing optimal electrode materials.

关键词： electrocatalysis nanomaterials solid oxide fuel cells solid oxide electrolysis cells exsolution nanoparticles

Night and day at the beach: Relating social life to location and infrastructure in a Brazilian city

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Frontiers of Architectural Research 2022年第6期11卷 1177-1192页

作者： Lucy Donegan Gabriel de Oliveira Madruga Natália Vale carneiro departamento de Arquitetura e Urbanismo Federal University of ParaíbaJoão PessoaParaíbaBrazil

Brazilian city beaches are public spaces favoring citizens *** studies relate built form and infrastructure with urban vitality and coastal studies underline uses as important for beach management,yet few researches relate form and infrastructure with beach *** daily life as essential for public spaces and that spatial form relates with uses,this paper assesses time-based relationships between built and natural physical attributes and social life on the beaches of João Pessoa,a coastal city in North-east *** attributes are investigated at city scale-beach type,street network centrality and topography-and seafront scale-land uses,public/private interfaces,public infrastructure,beach sections and water *** social life was surveyed online,enquiring peoples’beach choice,visiting time and place,activities and *** and street network follow topography and help configure shore and promenade for different *** central beaches have diverse land uses,well-equipped promenades and lighting and were popular night and day,while less central beaches had less infrastructure and were visited only by *** highlight how physical attributes facilitate uses and,together with peoples’evaluation,can inform urban beach design and planning.

关键词： Public space Social life Built environment Beaches Public infrastructure

Stepped machine learning for the development of mineral models: Concepts and applications in the pre-salt reservoir carbonate rocks

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Energy and AI 2021年第1期3卷 167-179页

作者： Lucas Abreu Blanes de Oliveira Luiz Felipe Niedermaier Custodio Thais Bortotti Fagundes Carina Ulsen Cleyton de Carvalho carneiro Petrobras–Petroleo Brasileiro S.A. Avenida Henrique Valadares 28CentroRio de Janeiro20231-030 Rio de JaneiroBrazil Universidade de Sao Paulo USPEscola PolitecnicaPraça Narciso de AndradeVila MathiasSantosSão Paulo 11013-560Brazil

Understanding rock mineralogy is essential for formation evaluation,improving the calculation of porosity and hydrocarbon *** primary method to obtain the mineralogy from a well is by applying a model to the geochemical tool’s chemical ***,creating a mineralogical model presents challenges such as the minerals’chemical composition and the decision to include a mineral in the *** traditional application of machine learning can make mineral models less realistic since conventional training is developed based on a set of minerals with different occurrences,lowering some minerals’*** present research proposes the stepped machine learning(SML),a stepped way to use machine learning to create a mineralogical model from chemical and mineralogical data.A database was assembled with the elemental concentration obtained with XRF analyses and the mineral concentrations obtained with XRD *** chemical elements were Al,Ca,Fe,K,Mg,Mn,Na,Si,and *** minerals were calcite,dolomite,quartz,clays,K-feldspar,plagioclase,and *** algorithms were tested:MLP,GAN,Random Forest,and XGBoost,with XGBoost showing the best *** was applied,where a mineral model results are used to train a subsequent *** allowed for a significant improvement in some models,notably to clays with an increase in R 2 from 0.597 to 0.853,quartz an increase from 0.673 to 0.869,and calcite,from 0.758 to 0.862.A decrease in the mean squared error of these minerals’models was also *** model was applied to the geochemical logs from three wells drilled in the Brazilian pre-salt,and the results were compared with XRD *** SML model was able to honor the mineral concentrations for different *** is demonstrated that the integration between machine learning tools and geological knowledge in SML was crucial for creating a representative mineralogical model.

关键词： minerals quartz reservoir

Flight performance and wing morphology in the bat Carollia perspicillata:biophysical models and energetics

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Integrative Zoology 2023年第5期18卷 876-890页

作者： Lucas de Oliveira carneiro Breno MELLADO Marcelo Rodrigues NOGUEIRA Ariovaldo Pereira da CRUZ-NETO Leandro Rabello MONTEIRO Laboratório de Ciências Ambientais Centro de Biociências e BiotecnologiaUniversidade Estadual do Norte FluminenseCampos dos GoytacazesRio de JaneiroBrasil departamento de Biodiversidade Universidade Estadual PaulistaRio ClaroSão PauloBrasil

Studies on functional performance are important to understand the processes responsible for the evolution of *** trait variation within species influences the energetic cost of locomotion and impacts life history traits,with ecological and evolutionary *** study examined wing morphology correlates of flight performance measured by energetic expenditure in the Seba’s short-tailed bat,Carollia *** the flight experiments,nature caught bats(59 females,57 males)were allowed to fly for 3 min in a *** each flight,thermographic images were taken to measure body temperature,and biophysical models were used to calculate sensible heat loss as a measure of energetic *** morphological traits were measured for each individual and associated with heat loss and power required to fly on performance *** morphological traits explained 7-10%of flight energetic cost,and morphologies with the best performance would save the energy equivalent to 9-30%of total daily *** optimal performance areas within the *** morphospace were consistent with predicted selection trends from the literature.A trade-off between demands for flight speed and maneuverability was *** loading and camber presented sexual *** morphological differences are likely associated with more economical but less maneuverable flight in females,leading them to fly more often in open areas along the forest *** findings demonstrate how small scale changes in wing morphology can affect life history strategies and fitness.

关键词： aerodynamics Chiroptera infrared thermography performance surfaces Phyllostomidae wing morphometrics

Intelligent negotiation model for ubiquitous group decision scenarios

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Frontiers of Information Technology & Electronic Engineering 2016年第4期17卷 296-308页

作者： Joao carneiro Diogo MARTINHO Goreti MARREIROS Paulo NOVAIS GECAD-Knowledge Engineering and decision Support Group Institute of EngineeringPolytechnic of PortoPorto 4200-072Portugal ALGORITMI Centre University of MinhoGuimaraes 4800-058Portugal

Supporting group decision-making in ubiquitous contexts is a complex task that must deal with a large amount of factors to succeed. Here we propose an approach for an intelligent negotiation model to support the group decision-making process specifically designed for ubiquitous contexts. Our approach can be used by researchers that intend to include arguments, complex algorithms, and agents' modeling in a negotiation model. It uses a social networking logic due to the type of communication employed by the agents and it intends to support the ubiquitous group decision-making process in a similar way to the real process, which simultaneously preserves the amount and quality of intelligence generated in face-to-face meetings. We propose a new look into this problem by considering and defining strategies to deal with important points such as the type of attributes in the multicriterion problems, agents' reasoning, and intelligent dialogues.

关键词： Group decision support systems Ubiquitous computing Automatic negotiation Social networks Multi-agent systems

Antinociceptive and anti-inflammatory activities of leaf extracts from Annona tomentosa ***

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Journal of Integrative Medicine 2017年第5期15卷 379-387页

作者： Lilian Uchoa carneiro Ilna Gomes da Silva Mirian Eliza Alves de Souza Wellington da Silva Cortes Mário Geraldo de Carvalho Bruno Guimaraes Marinho Postgraduate Program in Physiological Sciences Institute of Biological and Health SciencesFederal Rural University of Rio de JaneiroRio de Janeiro 23890-000Brazil Laboratory of Pharmacology Department of Physiological SciencesInstitute of Biological Sciences and HealthFederal Rural University of Rio de JaneiroRio de Janeiro 23890-000Brazil Postgraduate Program in Chemistry Department of ChemistryInstitute of Exact SciencesFederal Rural University of Rio de JaneiroRio de Janeiro 23890-000Brazil

OBJECTIVE：Annona tomentosa *** is a species not endemic to Brazil that belongs to the phytogeographic areas of the Amazon,Cerrado and *** known as“araticum rasteiro”or“araticum de moita”,*** is edible and tea made from the leaves has been used as an antiinflammatory by native *** is no scientific evidence for these uses of ***,especially those related to the control of pain and *** this reason,in the present study we evaluated the antinociceptive and anti-inflammatory activities of partitions from the methanolic extract of *** leaves（*** leaf methanolic extract（ATFM）in hexane partition：ATFM-H;ATFM in dichloromethane partition：ATFM-D;ATFM in ethyl acetate partition：ATFM-Ac;ATFM in butanol partition：ATFM-B）in ***：The antinociceptive effects of leaf extracts from *** were evaluated by abdominal writhing and tail-flick tests,while the anti-inflammatory effects were evaluated by paw oedema and air-pouch *** locomotor activity was evaluated with the open-field ***,we evaluated the possible action mechanism of ***,using naloxone,nitro-L-arginine methyl ester,glibenclamide,atropine,naltrindole and norbinaltorphimine in tail-flick *** productions of tumor necrosis factorα（TNF-α）and interleukin（IL）-1βwere also ***：The chromatographic fractionation of the partitions of the methanolic extract from the leaves of *** revealed the presence of diterpenes,flavonoids,and steroids *** the analysis of the hexane partition kaurenoic acid was identified as the major ***-H and ATFM-D had a significant antinociceptive effect in acute pain models in *** ATFM-H showed central antinociceptive effect from the involvement of theδopioid receptors,without causing alterations in the locomotor activity of the mice,while ATFM-D was effective in decreasing paw oedema and TNF-α and IL-1β ***：These results demon

关键词： Annona tomentosa cytokines opioid nociception

Niobium in Microalloyed Steels Unchallenged for Its Main Applications

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Journal of Iron and Steel Research International 2011年第S1期18卷 57-65页

作者： Nogueira Marcos A Stuart carneiro Tadeu Companhia Brasileira de Metalurgia e Minerao Technical DirectorSao PauloBrazil Companhia Brasileira de Metalurgia e Minerao Managing DirectorSao PauloBrazil

During the past five decades niobium has emerged as the most important microalloying element in high strength *** first theories to explain its role were presented in the seminal publications of Woodhead,Morrison and *** niobium microalloyed steels are unchallenged for their main *** examples include linepipe for gas transportation,automotive steels used in body-in-white and structural parts,shipbuilding,steel towers and steel structures in civil construction that exhibit better fire resistance and seismic load *** technology for steelmaking helped emphasize the superior overall properties that can be attained with the use of *** linepipe is the best example of cleaner steel with carbon levels below 0.05% manufactured *** niobium microalloyed steels present the optimal balance of strength,toughness,weldability and *** paper describes the evolution of the technology associated with niobium in microalloyed steels,technology that secured its status as the efficient solution to solving today’s challenges:safety,energy efficiency and environmental *** paper also presents evidence that enhances the case that there is a secure,stable,long-term supply of the ferroniobium used to manufacture these steels.

关键词： Niobium in Microalloyed Steels Unchallenged for Its Main Applications