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EEGcorco: a computer program to simultaneously calculate and statistically analyze EEG coherence and correlation

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Journal of Biomedical Science and Engineering 2011年第12期4卷 774-787页

作者： miguel angel guevara Marisela Hernández-González Araceli Sanz-Martin Claudia Amezcua 不详

EEGcorco is a computer program designed to analyze the degree of synchronization between two electroencephalographic signals (EEG) by mean the analysis of correlation and coherence index. The correlation and coherence values permit the quantitative determination of the similarity among EEG signals from homologous areas of the cerebral hemispheres (interhemispheric), and among localized areas within one cerebral hemisphere (intrahemispheric). EEG coherence is a function of frequency;thus it is commonly presented in a spectral manner (coherence values in every frequency of the spectrum), in contrast, the correlation function has been employed mainly to search periodic components of bioelectrical signals, and normally appears as punctual values defined in time, hence it is not common calculate correlation spectra. EEGcorco offers an easy and novel way to calculate correlation spectra by mean the application of the Fast Fourier Transformation (FFT) to digitized EEG signals. Both, correlation and coherence spectra are obtained in both independent frequencies and frequencies grouped in wide bands. Moreover, the program applies parametric statistical analyses to those coherence and correlation spectra also, for each individual frequency and for the frequencies grouped in bands. The program functions on any PC-compatible computer equipped with a Pentium or superior processor and a minimum of 512 Mb of RAM memory (though the higher the capacity the better). The space required on the hard disk depends on the signals to be analyzed, as the output takes the form of files in text format that occupy very little space. The program has been elaborated completely in the Delphi environment for the Windows operating system. The efficacy and versatility of EEGcorco allow it to be easily adapted to different experimental and clinical needs.

关键词： EEG EEG Coherence EEG Correlation

Electroencephalographic Correlates of Sexual Arousal Induced by Sexually-Explicit Reading in Human Females

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Journal of Behavioral and Brain Science 2018年第11期8卷 599-614页

作者： miguel angel guevara Carolina Gomez-Navarro Claudia Amezcua-Gutierrez Marisela Hernandez-Gonzalez Anders Agmo Institute of Neuroscience CUCBAUniversity of GuadalajaraGuadalajaraJaliscoMexico Psychology Department Tromso UniversityTromsoNorway

This study explored the cortical functionality in young women while reading a sexually-explicit text. Electroencephalographic activity (EEG) was recorded in heterosexual women while reading either a sexually-explicit text or one with neutral content. Absolute power (AP) and the degree of EEG synchronization among the prefrontal, temporal and parietal cortices were analyzed for the different EEG bands. To evaluate sexual arousal, valence and general activation, Likert-type and Manikin scales were applied. Subjects scored the sexually-explicit text as more pleasurable, and reported greater general activation and sexual arousal than while reading the neutral one. During reading of the sexually-explicit text only, they showed a higher AP in the beta and gamma bands in temporal areas in both hemispheres, and in the theta band in parietal ones, with a lower degree of EEG synchronization between prefronto-temporal areas in the fast bands. Results show that both hemispheres were activated in these sexually-aroused women. The low bilateral synchronization between prefrontal and temporal regions indicates the independent functionality of these cortices, which could be a requirement for inducing and maintaining sexual arousal during reading of sexually-explicit texts in women. These data should broaden our knowledge of the cortical mechanisms that underlie sexual arousal in women.

关键词： Sexual Arousal EEG Sexually-Explicit Reading Erotic Reading Women

RompecPC: A computerized program to create and solve jigsaw puzzles

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Journal of Biomedical Science and Engineering 2013年第7期6卷 717-721页

作者： miguel angel guevara Marai Pérez Hernández Marisela Hernández González Araceli Sanz-Martin Sonia Ramírez Zapata Instituto de Neurociencias Centro Universitario de Ciencias Biológicas y Agropecuarias Universidad de Guadalajara Guadalajara México Universidad Autónoma Metropolitana Unidad Xochimilco México D.F. México

RompecPC is a computerized program designed to create and assemble jigsaw puzzles. The program automatically records the solver’s responses as the number of pieces positioned correctly, the number of correct and incorrect movements, the number of times that she/he attempts to move a piece to the same place (perseverations), and the latency and place to which each piece is moved or attempted to be moved. These features facilitate the implementation and evaluation of puzzles while also reducing human error. Therefore, RompePC is a useful tool for the neuropsychological assessment of visuospatial skills in both clinical and experimental research.

关键词： Computerized Testing Neuropsychological Test Jigsaw Puzzles Visuospatial Abilities

Prefrontal-Parietal Correlation during Performance of a Visuospatial Working Memory Task in Children, Adolescents and Young Adults

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Journal of Behavioral and Brain Science 2015年第10期5卷 448-457页

作者： miguel angel guevara Jorge Carlos Hevia-Orozco Araceli Sanz-Martin Lucía Ester Rizo-Martínez Marisela Hernández-González Mayra Linné Almanza-Sepúlveda Instituto de Neurociencias CUCBA Universidad de Guadalajara Guadalajara México

Development of the prefrontal cortex and its connectivity with different cortical areas has strong implications for the improvement of working memory. The aim of this research was to characterize the interhemispheric (INTER) prefrontal and hemispheric (INTRA) frontopolar-dorsolateral prefrontal and dorsolateral prefrontal-parietal correlation (r) in children, adolescents and adults during performance of a visuospatial working memory task (VSWM). INTERr and INTRAr of 36 different aged male participants (11 - 13, 18 - 20 and 26 - 30 years old) were calculated during performance of the Corsi Block-Tapping task, which assessed VSWM. On this task, children showed lower correct responses than adolescents and adults. Adults also showed lower total execution times than children and adolescents, with a more efficient performance. On the EEGs, the older groups showed both higher interfrontal correlations and left and right prefronto-parietal correlations than children. According to our results, the progressive efficiency in VSWM is related to differences in EEG patterns among children, adolescents and adults.

关键词： Corsi Block-Tapping Task EEG Correlations Development Visuospatial Working Memory

Ethanol Effects on Cortical EEG Correlation and Sexual Behavior in Male Rats

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Journal of Behavioral and Brain Science 2014年第2期4卷 92-98页

作者： miguel angel guevara Marisela Hernández-González Mayra Linné Almanza-Sepúlveda Diego Radberto Chapa García Abascal Pilar Durán Carolina Sotelo Tapia Fabricio Luna Torres Departamento de Biología Celular Facultad de Ciencias Universidad Nacional Autónoma de México México DF México Instituto de Neurociencias Universidad de Guadalajara Guadalajara Jalisco México

Ethanol affects sexual behavior drastically, as much as its execution as well as its motivation. Ethanol is a central nervous system depressant and the prefrontal cortex (PFC) is one of the cortical areas most sensitive to its effects. This prefrontal area participates in the modulation of the cognitive control, and furthermore, by mean of connections with the parietal cortex (PC) plays an important role in the processing of sexually relevant stimuli. Considering that it has been reported that the ethanol affects the proper functioning of these cortical areas, particularly decreasing the degree of electroencephalographic (EEG) coupling or correlation between them, the aim of this study was to characterize the effect of a low dose of ethanol on EEG correlation, as well determining if this effect is associated with impaired sexual behavior in male rats. Nine male rats unilaterally implanted were simultaneously recorded the EEG from the PFC and PC to calculate the degree of EEG synchronization (correlation, r) between both cortices during the first 40 minutes post administration of 0.75 g/kg of ethanol. At the end of the EEG recording, the males were submitted to copulatory behavior with a receptive female rat. The ethanol administration was associated with a decreased intrahemispheric correlation of the fast bands between PFC and PC, as well as with an increased mount and intromission latency. This data showed that ethanol in moderate doses decreased the coupling degree between cortices. It is likely that this functional disconnection between the PFC and PC after the ethanol administration could be associated with the difficulty in discriminating incentive value of the sexual stimuli so that decreased the sexual motivation but not the performance of the copulatory parameters in the male rat.

关键词： Ethanol Sexual Behavior EEG Prefrontal Cortex Parietal Cortex Rat

Proteomic analysis of the biomineralization of spherical Brushite produced from a wheat bran aqueous extract

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FOOD BIOSCIENCE 2023年第3期53卷 1951-1959页

作者： Carreno-Marquez, Ivan Jalil Anton Balandran-Quintana, Rene Renato Azamar-Barrios, Jose Antonio Huerta-Ocampo, Jose angel Mendoza-Wilson, Ana Maria Montfort, Gabriela Ramos-Clamont Encarnacion-guevara, Sergio Hernandez-Ortiz, Magdalena Ctr Invest Alimentac & Desarrollo AC Coordinac Tecnol Alimentos Origen Vegetal Carretera Gustavo Enrique Astiazaran Rosas 46 Hermosillo 83304 Sonora Mexico IPN Dept Fis Aplicada Unidad Merida Ctr Invest & Estudios Avanzados Carretera Antigua Progreso Km 6 Merida 97310 Yucatan Mexico CONACYT Coordinac Ciencia Alimentos Ctr Invest Alimentac & Desarrollo AC Hermosillo Sonora Mexico Ctr Invest Alimentac & Desarrollo AC Coordinac Ciencia Alimentos Hermosillo Sonora Mexico UNAM Ctr Ciencias Genom Cuernavaca Morelos Mexico

Wheat bran aqueous extracts provide phosphate ions and other necessary but unknown biomolecules for synthesizing spherical microparticles of dicalcium phosphate dihydrate or Brushite, which is interesting for the food industry due to its delivering nutraceuticals properties. This study tests the hypothesis that proteins are the scaffold biomolecules over which the Brushite crystals grow. Brushite was synthesized from the wheat bran aqueous extract by adding calcium ions. Precipitated particles were characterized by x-ray diffraction, scanning electron microscopy, energy dispersive, and infrared spectroscopies, corroborating a single Brushite phase. The Brushite particles were demineralized for searching and identifying intracrystalline proteins through mass spectroscopy and bioinformatics. Six hundred and seventy-six proteins were identified in the Brushite and analyzed by their relative abundance and intrinsic disorder, giving 20 top proteins as scaffold candidates. Additionally, wheat bran aqueous extract was subjected to size exclusion chromatography to explore if a fraction is responsible for the Brushite synthesis. Four chromatographic fractions were obtained and treated as the aqueous extract to induce mineralization. Three fractions produced Brushite, from which two produced spherical brushite particles with diameters between 50 and 200 mu m. Particle size and morphology in one of the latter fractions matched those precipitated by the raw aqueous extract. Results strongly suggest that specific proteins in the wheat bran aqueous extract may have a role as a scaffold in spherical Brushite biomineralization.

关键词： Spherical brushite Wheat bran Calcium phosphates Protein scaffolds