检索结果-南通市图书馆

加夫列尔·加西亚·马尔克斯图书馆,巴塞罗那,西班牙

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世界建筑 2024年第5期 76-81页

作者：无 Elena Orte Guillermo sevillano Marta Romero Jesús Lopez Luis sierra Ana Patricia Minguito Pablo Corroto María Abellán sara Contreras RitaÁlvarez Tabio miguelÁngel Maure Jesús Granada(摄影) sUMA建筑设计事务所不详

加布里埃尔·加西亚·马尔克斯图书馆是巴塞罗那的第40座图书馆,也是巴塞罗那30年计划的结晶。该计划旨在建立一个由优秀社区与区域设施组成的密集网络。这座图书馆位于圣马蒂德普罗旺斯区,为53,000人提供服务。关联式建筑图书馆被设计... 详细信息

加布里埃尔·加西亚·马尔克斯图书馆是巴塞罗那的第40座图书馆,也是巴塞罗那30年计划的结晶。该计划旨在建立一个由优秀社区与区域设施组成的密集网络。这座图书馆位于圣马蒂德普罗旺斯区,为53,000人提供服务。关联式建筑图书馆被设计成一座雕塑式实体建筑,让人联想到堆叠的书籍及其折叠的书页。该馆坐落在一处高架广场上,方便周围行人来往。同时,它又在空地上悬挑而出,门廊由现有的树木环绕,形成了一座城市大厅。不同大小及结构的开口定义了其不同立面与周围环境的关系。

关键词：巴塞罗那普罗旺斯周围环境加布里埃尔加西亚·马尔克斯图书馆关联式西班牙

Emerging and multifaceted potential contributions of polyphenols in the management of type 2 diabetes mellitus

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World Journal of Diabetes 2024年第2期15卷 154-169页

作者： Ileana González Cristian Lindner Ivan schneider Erik Diaz miguel Angel morales Armando Rojas Biomedical Research Laboratories Faculty of MedicineCatholic University of MauleTalca 34600000Chile Department of Radiology Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Centre of Primary Attention South Metropolitan Health ServiceSantiago 3830000Chile Faculty of Medicine Catholic University of MauleTalca 3460000Chile Molecular and Clinical Pharmacology Program Institute of Biomedical SciencesUniversity of ChileSantiago 8320000Chile

Type 2 diabetes mellitus(T2DM)is recognized as a serious public health concern with a considerable impact on human life,long-term health expenditures,and substantial health *** this context,the use of dietary polyphenols to prevent and manage T2DM is widely *** dietary compounds exert their beneficial effects through several actions,including the protection of pancreatic islet β-cell,the antioxidant capacities of these molecules,their effects on insulin secretion and actions,the regulation of intestinal microbiota,and their contribution to ameliorate diabetic complications,particularly those of vascular *** the present review,we intend to highlight these multifaceted actions and the molecular mechanisms by which these plant-derived secondary metabolites exert their beneficial effects on type 2 diabetes patients.

关键词： Polyphenols Antioxidants Oxidative stress Type 2 diabetes mellitus Health benefits

science Letters:Blind spot detection using vision for automotive applications

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Journal of Zhejiang University-science A(Applied Physics & Engineering) 2008年第10期9卷 1369-1372页

作者： miguel ngel sOTELO José BARRIGA Department of Electronics University of Alcalá Alcalá de Henares 28871 Spain

This paper describes a vision-based system for blind spot detection (BsD) in intelligent vehicle applications. A camera is mounted in the lateral mirror of a car with the intention of visually detecting cars that are located in the so-called blind spot and cannot be perceived by the vehicle driver. The detection of cars in the blind spot is carried out using computer vision techniques, based on optical flow and a double-stage data clustering technique for robust vehicle detection.

关键词： Computer vision Optical flow Blind spot detection (BsD) Intelligent vehicles

The Return of Civilisations

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International Understanding 2024年第1期 20-24页

作者： miguel Angel moratinos the United nations

I was pleasantly surprised when visiting the new Louvre Museum in Abu Dhabi,magnificently designed,and created by the great French architect Jean nouvel to prove the creative force of the world's diverse *** of them a... 详细信息

关键词： looking island creative

Oxygen tension modulates cell function in an in vitro three-dimensional glioblastoma tumor model

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Bio-Design and Manufacturing 2024年第3期7卷 307-319页

作者： sen Wang siqi Yao na Pei Luge Bai Zhiyan Hao Dichen Li Jiankang He J.miguel Oliveira Xiaoyan Xue Ling Wang Xinggang Mao state Key Laboratory for Manufacturing system Engineering Xi’an Jiaotong UniversityXi’an 710054China school of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710054China nMPA Key Laboratory for Research and Evaluation of Additive Manufacturing Medical Devices Xi’an Jiaotong UniversityXi’an 710054China 3B’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVs/3B’s-PT Government Associate Laboratory 4806-909 Braga/Guimar˜aesPortugal Department of Pharmacology School of PharmacyFourth Military Medical UniversityXi’an 710032China Department of neurosurgery Xijing HospitalFourth Military Medical UniversityXi’an 710032China

Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor ***,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor *** study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I *** also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and ***,it compares two-dimensional(2D)and 3D *** comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D ***,the two models yielded significantly different cell ***,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D *** results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture *** developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.

关键词： Hypoxia Glioma Three-dimensional glioma model In vitro

Effect of the Density of Molten Metal on the Raining Phenomenon in Horizontal Centrifugal Casting

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Open Journal of Applied sciences 2024年第7期14卷 1918-1926页

作者： miguel A. Barron Joan Reyes Departamento de Materiales Universidad Autonoma Metropolitana Azcapotzalco Ciudad de Mexico Mexico

In this work the influence of the density of the molten metal on the emergence of the raining phenomenon in the horizontal centrifugal casting process is numerically studied. Transient 2D numerical simulations were carried out using Computational Fluid Dynamics software. Three molten metals with different density, namely aluminum, iron and lead, and three angular frequencies, namely 50, 66 and 77 rad/s were considered. It is found that the density of the molten metal significantly affects the emergence, transient or permanent, of the rain phenomenon. However, the magnitude and duration of the rain phenomenon depend on the angular frequency of the rotating mold. Likewise, since gravitational forces affect the metal according to its density, the value of the critical rotation speed of the mold is also affected.

关键词： Angular Frequency Centrifugal Force Computational Fluid Dynamics Critical Rotation speed G Factor Horizontal Centrifugal Casting Molten Metal Density

Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

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Food science and Human Wellness 2024年

作者： Emily P.Laveriano-santos sara Castro-Barquero Camila Arancibia-Riveros Ana María Ruiz-León Rosa Casas Ramón Estruch Patricia Bodega Mercedes de miguel Amaya de Cos-Gandoy Jesús Martínez-Gómez Gloria santos-Beneit Juan M.Fernández-Alvira Rodrigo Fernández-Jiménez Rosa M.Lamuela-Raventós Anna Tresserra-Rimbau The Zena and Michael A.Wiener Cardiovascular Institute， Icahn school of Medicine at Mount sinai Department de nutrició， Ciències de l'Alimentació I Gastronomia， XIA， Facultat de Farmàcia i Ciències de l'alimentació， Institut de Recerca en nutrició i seguretat Alimentària (InsA-UB)， Universitat de Barcelona Department of Internal Medicine， Hospital Clínic， Institutd'Investigacions Biomèdiques August Pi I sunyer (IDIBAPs)， University of Barcelona Consorcio CIBER， M.P.Fisiopatología de la Obesidad y nutrición (CIBERObn)， Instituto de salud Carlos III (IsCIII) Mediterranean Diet Foundation 5. Foundation for science， Health and Education (sHE) 6. Centro nacional de Investigaciones Cardiovasculares (CnIC) CIBER de Enfermedades Cardiovasculares (CIBERCV) 9. Hospital Universitario Clínico san Carlos

Background: The protective role of (poly)phenols against metabolic disorders has been extensively studied in adults but not in ***: To assess associations of dietary (poly)phenols and their subclasses with cardiometabolic health parameters in adolescents. Methods: A cross-sectional study was conducted in 944 individuals aged 11 to 14 years enrolled in the sI! Program for secondary schools trial (nCT03504059). (Poly)phenol intake was assessed using semi-quantitative food frequency questionnaires and the Phenol-Explorer database. The measured cardiometabolic parameters were waist circumference (WC) age-sex z-score， blood pressure (BP) age-sex z-score， blood glucose (BG)， triglycerides (TG)， and high-density lipoprotein cholesterol (HDL-c). Multilevel mixed-effect linear regression models were applied to examine the association between (poly)phenol quintiles and cardiometabolic health ***: Compared to the lowest quintile， adolescents in the highest quintile of total (poly)phenol intake had lower WC z-scores (β=-0.09， 95%CI=-0.09;-0.08， P-for trend=0.002)， mean arterial pressure z-scores (β =-0.11， 95%CI=-0.12;-0.09， P-for trend=0.206)， and HDL-c (β=-1.52， 95%CI=-2.90;-0.14， P-for trend=0.108)， after multivariable adjustment. The WC z-scores (β=-0.11， 95%CI=-0.19;-0.03， P-for trend=0.013) and HDL-c (β=-2.16， 95%CI=-3.78;-0.53， P-for trend=0.046) were lower in the highest quintile of flavonoid intake compared to the lowest quintile. The highest quintile of phenolic acid intake was associated with a lower WC z-score (β=-0.14， 95%CI=-0.26;-0.02， P-for trend=0.011) and TG levels (β=-8.83， 95%CI=-12.37;-5.30， P-for trend nd the highest quintile of stilbene intake with lower BG (β=-1.83， 95%CI= -3.103;-0.64， P-for trend nd TG (β=-3.22， 95%CI= -4.95;-1.49， P-for trend=0.034)， and with higher HDL-c (β=2.328， 95%CI= 1.40;3.17， P-for trend=0.466) compared to the lowest quintile. Conclusion: A higher intake of (poly)phenols， espe

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Modeling Bacterial species: Using sequence similarity with Clustering Techniques

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Computers, Materials & Continua 2021年第8期68卷 1661-1672页

作者： miguel-Angel sicilia Elena garcía-Barriocanal Marçal mora-Cantallops salvador sánchez-Alonso Lino González University of Alcalá Alcaláde Henares(Madrid)28871Spain Camilo JoséCela University Madrid28007Spain

Existing studies have challenged the current definition of named bacterial species,especially in the case of highly recombinogenic *** has led to considering the use of computational procedures to examine potential bacterial clusters that are not identified by species *** paper describes the use of sequence data obtained from MLsT databases as input for a k-means algorithm extended to deal with housekeeping gene sequences as a metric of similarity for the clustering *** implementation of the k-means algorithm has been developed based on an existing source code implementation,and it has been evaluated against MLsT *** point out to potential bacterial clusters that are close to more than one different named species and thus may become candidates for alternative classifications accounting for genotypic *** use of hierarchical clustering with sequence comparison as similarity metric has the potential to find clusters different from named species by using a more informed cluster formation strategy than a conventional nominal variant of the algorithm.

关键词： Clustering bacterial species k-means sequence alignment

一种优化开关磁阻电机换相区控制策略的高效率转矩分配函数

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电工技术学报 2024年第6期39卷 1671-1683页

作者：杨帆陈昊李晓东 miguel Pablo Aguirre Muhammad Asghar saqib 中国矿业大学电气工程学院徐州221116 新能源电动车技术与装备中东欧国家国际联合研究中心徐州221008 江苏省高校新能源发电与电动车国际合作联合实验室徐州221008 徐州市新能源电动车技术与装备重点实验室徐州221008 澳门科技大学创新工程学院中国澳门999078 布宜诺斯艾利斯工学院电子工程系布宜诺斯艾利斯B1636 巴基斯坦工程技术大学电气工程系讷瓦布沙阿44000

转矩分配函数被广泛应用于抑制开关磁阻电机的转矩脉动。然而,输入相转矩跟踪不足或者输出相产生较大的负转矩这两种情况通常会导致电机的转矩脉动难以得到有效抑制,并降低电机的运行效率。因此,为了能够有效降低电机的转矩脉动并提高... 详细信息

转矩分配函数被广泛应用于抑制开关磁阻电机的转矩脉动。然而,输入相转矩跟踪不足或者输出相产生较大的负转矩这两种情况通常会导致电机的转矩脉动难以得到有效抑制,并降低电机的运行效率。因此,为了能够有效降低电机的转矩脉动并提高电机的效率,提出了一种新型的转矩分配函数控制策略。在提出的转矩分配函数控制策略中,电机的换相区域分为两个区域。在前一区域中,通过降低输入相转矩分配的比例,可以实现输入相实际转矩快速跟踪参考转矩,电机的转矩脉动有效降低。同时由于在输入相电感变化率较低时减少输入相分配的转矩,从而输入相的峰值电流随之降低,电机的转矩电流比提高。在后一区域中,将输出相的电流在转子对齐位置附近处减小到0,以避免产生较大的负转矩。因此,在所提出的方案下,电机的转矩脉动得到有效抑制,电机的效率也得到了提高。为了验证该方法的有效性,在一台12/8三相开关磁阻电机上进行了仿真和实验。结果表明,所提出的转矩分配函数控制策略能有效降低开关磁阻电机转矩脉动,也能有效地提高开关磁阻电机的运行效率。

关键词：开关磁阻电机转矩分配函数负转矩转矩电流比效率