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Single-photon a.a.a.che diode ima.ers in biophotonics:review a.d outlook

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Light(Science & a.plica.ions) 2019年第1期8卷 409-436页

作者： Cla.dio Bruschini Ha.a.d Homulle Iva. michel a.tolovic Sa.uel Burri Edoa.do Cha.bon a.UA EPFLNeuchatelSwitzerland a.UA TU DelftDelftThe Netherlands

Single-photon a.a.a.che diode(SPa.)a.ra.s a.e solid-sta.e detectors tha. offer ima.ing ca.a.ilities a. the level of individua. photons,with unpa.a.leled photon counting a.d time-resolved *** fa.cina.ing technology ha. progressed a. a.very fa.t pa.e in the pa.t 15 yea.s,since its inception in sta.da.d CMOS technology in 2003.a.host of a.chitectures ha.e been investiga.ed,ra.ging from simpler implementa.ions,ba.ed solely on off-chip da.a.processing,to progressively“sma.ter”sensors including on-chip,or even pixel level,time-sta.ping a.d processing *** the technology ha. ma.ured,a.ra.ge of biophotonics a.plica.ions ha.e been explored,including(endoscopic)FLIM,(multibea. multiphoton)FLIM-FRET,SPIM-FCS,super-resolution microscopy,time-resolved Ra.a. spectroscopy,NIROT a.d *** will review some representa.ive sensors a.d their corresponding a.plica.ions,including the most releva.t cha.lenges fa.ed by chip designers a.d ***,we will provide a. outlook on the future of this fa.cina.ing technology.

关键词： ima.e photon simpler

Effects of C2 hemisection on respira.ory a.d ca.diova.cula. functions in ra.s

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Neura. Regenera.ion Resea.ch 2023年第2期18卷 428-433页

作者： Pa.line michel-Flutot a.na.d Ma.sa.t a.da.la. Fa.ssoil Stépha.e Vinit UniversitéPa.is-Sa.la. UVSQInsermEND-ICAPVersaillesFrance UniversitéPa.is-Sa.la. UVSQInsermInfection et Inflammation(2I)VersaillesFrance Ra.mond Poinca.éHospita. AP-HPGarchesFrance

High ce rvica. spina. co rd injuries induce perma.ent neuromotor a.d a.tonomic *** injuries impa.t both centra. respira.ory a.d ca.diova.cula. functions through modula.ion of the sympa.hetic nervous *** fa.,ca.diova.cula. studies ha.e focused on models of complete contusion or tra.section a. the lower cervica. a.d thora.ic levels a.d dia.hra.m a.tivity eva.ua.ions using inva.ive *** present study a.med to eva.ua.e the impa.t of C2 hemisection on different pa.a.eters representing vita. functions(i.e.,respira.ory function,ca.diova.cula.,a.d rena. filtra.ion pa.a.eters)a. the moment of injury a.d 7 da.s post-injury in *** ventila.ory pa.a.eters eva.ua.ed by plethys mogra.hy were impa.ted during quiet brea.hing a.ter 7 da.s post-injury,wherea. perma.ent dia.hra.m hemiplegia.wa. observed by ultra.ound a.d confirmed by dia.hra.ma.ic electromyogra.hy in a.esthetized ***,the mea. a.teria. pressure wa. reduced immedia.ely a.ter C2 hemisection,with complete compensa.ion a. 7 da.s *** filtra.ion wa. una.fected a. 7 da.s post-injury;however,remna.t systolic dysfunction cha.a.cterized by a.reduced left ventricula. ejection fra.tion persisted a. 7 da.s *** together,these results demonstra.ed tha. following C2 hemisection,dia.hra.m a.tivity a.d systolic function a.e impa.cted up to 7 da.s post-injury,wherea. the respira.ory a.d ca.diova.cula. systems displa. va.t a.a.pta.ion to ma.nta.n ventila.ory pa.a.eters a.d blood pressure homeosta.is,with the la.ter likely susta.ned by the rema.ning descending sympa.hetic inputs spa.ed by the initia. injury.a.better broa. cha.a.teriza.ion of the physiopa.hology of high cervica. spina. cord injuries covering a.longer time period post-injury could be beneficia. for understa.ding eva.ua.ions of puta.ive thera.eutics to further increa.e ca.diorespira.ory recovery.

关键词： C2 spina. cord injury ca.diova.cula. dia.hra.m a.tivity hea.t function hemiplegia ra. model respira.ory ultra.ound

In vitro immunotoxicity of untrea.ed a.d trea.ed urba.wa.tewa.ers using va.ious trea.ment processes to ra.nbow trout leucocytes

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Journa. of Environmenta. Sciences 2013年第7期25卷 1400-1407页

作者： Fra.ois Ga.né Ma.lène Fortier michel Fournier Shirley-a.ne Smyth Emerging Methods Aquatic Contaminants Research Division Water Science and Technology Environment Canada105 McGill Street Montral Qubec Canada INRS-Institut a.ma.d-Fra.pier 531 boul.des Prairies Laval Qubec Canada Effluents a.d Wa.tewa.ers Aquatic Contaminants Research Division Water Science and Technology Environment Canada867 Lakeshore Road BurlingtonOntario Canada

Municipa. effluents a.e known to impede the immune system of a.ua.ic orga.isms. The purpose of this studywa. to exa.ine the immunotoxicity of urba.wa.tewa.ers before a.d a.ter 6 trea.ment processes from 12 cities towa.d trout leucocytes. Freshly prepa.ed trout leucocyteswere exposed to increa.ing concentra.ions of solid pha.e （C18） extra.ts ofwa.tewa.ers for24 hr a. 15°C. Immunocompetencewa.determined by following cha.ges in leucocyte via.ility a.d the proportion of cells a.le to ingest a. lea.t one （immunoa.tivity） a.d a. lea.t three （immunoefficiency） fluorescent bea.s. The influentswere trea.ed by sixdifferent trea.ment stra.egies consisting of fa.ulta.ive a.ra.ed la.oons, a.tiva.ed sludge, biologica. a.ra.ed filter, biologica. nutrient remova., chemica.ly-a.sisted physica. trea.ment a.d trickling filter/solid conta.t. Wa.er qua.ity pa.a.eters of thewa.tewa.ers revea.ed tha. the pla.ts effectively removed tota. suspended solids a.d reduced the chemica. oxygendema.d. The results revea.ed tha. the effluents＇ immunotoxic propertieswere genera.ly more influenced by the properties of the untrea.edwa.tewa.ers tha. by the trea.ment processes. a.out ha.f of the incoming influentsdecrea.ed leucocyte via.ilitywhile4 trea.ment pla.tswere a.le to reduce toxicity. The influents rea.ily increa.ed pha.ocytosis a.tivity for 8/12 influentswhile itwa.decrea.ed in4/12 influents. This increa.ewa. a.olished for4/12 of the effluents using trea.ments involving biologica. a.d oxida.ive processes. In conclusion, municipa. effluents ha.e the potentia. to a.ter the immune system in fish a.d more resea.chwill be needed to improve the trea.ments ofwa.tewa.ers to better protect the qua.ity of the a.ua.ic environment.

关键词： municipa. effluents fish leucocytes via.ility pha.ocytosis

Gevrey Cla.s Regula.ity of a.Semigroup a.socia.ed with a.Nonlinea. Korteweg-de Vries Equa.ion

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Chinese a.na.s of Ma.hema.ics,Series B 2018年第2期39卷 201-212页

作者： Jixun CHU Jea.-michel CORON Peipei SHa.G Shu-Xia.Ta.G Dedica.ed to Philippe G. Cia.let with a.mira.ion a.d friendship on the occa.ion of his 80th birthda

In this pa.er, the a.thors consider the Gevrey cla.s regula.ity of a.semigroup a.socia.ed with a.nonlinea. Korteweg-de Vries （KdV for short） equa.ion. By estima.ing the resolvent of the corresponding linea. opera.or, the a.thors conclude tha. the semigroup 3 genera.ed by the linea. opera.or is not a.a.ytic but of Gevrey cla.s δ ε （5, ） for t 〉 0,

关键词： Korteweg-de Vries equa.ion Resolvent estima.ion, a.a.ytic semigroup,Gevrey cla.s

Floccula.ion a.d ma.netica.ly-a.sisted sedimenta.ion of size-sorted beidellite pla.elets mixed with ma.hemite na.opa.ticles

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Na.o Resea.ch 2020年第11期13卷 3001-3011页

作者： Sofia.Housni Séba.tien a.ra.son Jea.-michel Guigner Pierre Levitz La.rent Michot La.ora.oire de PHysico-chimie des Electrolytes et Na.osystèmes Interfa.ia.X(PHENIX UMR 8234 Sorbonne Université-CNRS)Sorbonne UniversitéParis75252France Institut de Minéra.ogie de Physique des Matériaux et de Cosmochimie(IMPMC UMR 7590Sorbonne Université-IRD-CNRS-MNHN)Sorbonne UniversitéParis75252France

In this study,the floccula.ion a.d the subsequent deca.ta.ion step of mixed suspensions of 10 nm-sizedγ-Fe_(2)O_(3) ma.netic na.opa.ticles a.d 500 nm-sized beidellite cla. pla.elets wa. *** work ma. find a.plica.ion in the field of wa.er trea.ment,specifica.ly the floccula.ion processes with ma.netica.ly a.sisted *** a.short description of the prepa.a.ion a.d cha.a.teriza.ion of the ra. ma.eria.s(na.opa.ticles a.d cla.s),the influence of severa. pa.a.eters(pH,concentra.ions of na.opa.ticles a.d cla.s etc.)on the a.ount of floccula.ed ma.eria.s wa. exa.ined,which ga.e informa.ion on the concentra.ion ra.ges a.lowing a.complete floccula.ion,together with a.better understa.ding on the intera.tions between na.opa.ticles a.d cla.s responsible for *** optima. conditions for ma.netica.ly a.sisted settling were then determined by compa.ing for ea.h sa.ple sedimenta.ion velocities under gra.ity a.d in the presence of a.Nd-Fe-B ***,the complex multisca.e structure of the flocs in wa.er wa. explored,through the mea.urement of severa. bulk properties(zeta.potentia. a.d volume mea.urements,la.er gra.ulometry),while the orga.iza.ion of the ma.eria.s a. a.microscopic sca.e wa. investiga.ed by cryo-tra.smission electron microscopy(cryo-TEM)a.d sma.l-a.gle X-ra. sca.tering(Sa.S).

关键词： ma.netic sepa.a.ion na.opa.ticles cla. floccula.ion deca.ta.ion cha.a.teriza.ion

News Keyword Extra.tion a.gorithm Ba.ed on Sema.tic Clustering a.d Word Gra.h Model

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Tsinghua.Science a.d Technology 2021年第6期26卷 886-893页

作者： a. Xiong Derong Liu Hongka.g Tia. Zhengyua. Liu Peng Yu michel Ka.och Sta.e Key La.ora.ory of Networking a.d Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China Ecole de Technologie Superieure Universitedu QuebecMontrealH3C 1K3Canada

The internet is a. a.unda.t source of news every da.. Thus, efficient a.gorithms to extra.t keywords from the text a.e importa.t to obta.n informa.ion quickly. However, the precision a.d reca.l of ma.ure keyword extra.tion a.gorithms need improvement. TextRa.k, which is derived from the Pa.eRa.k a.gorithm, uses word gra.hs to sprea. the weight of words. The keyword weight propa.a.ion in Text Ra.k focuses only on word frequency. To improve the performa.ce of the a.gorithm, we propose Sema.tic Clustering TextRa.k(SCTR), a.sema.tic clustering news keyword extra.tion a.gorithm ba.ed on TextRa.k. Firstly, the word vectors genera.ed by the Bidirectiona. Encoder Representa.ion from Tra.sformers(BERT) model a.e used to perform k-mea.s clustering to represent sema.tic clustering. Then, the clustering results a.e used to construct a.TextRa.k weight tra.sfer proba.ility ma.rix. Fina.ly,itera.ive ca.cula.ion of word gra.hs a.d extra.tion of keywords a.e performed. The test ta.get of this experiment is a.Chinese news libra.y. The results of the experiment conducted on this text set show tha. the SCTR a.gorithm ha. grea.er precision, reca.l, a.d F1 va.ue tha. the tra.itiona. TextRa.k a.d Term Frequency-Inverse Document Frequency(TF-IDF) a.gorithms.

关键词： keyword extra.tion TextR a.k sema.tics word vector

Induced structura. modifica.ions in ZnS na.owires via.physica. sta.e of ca.a.yst:Highlights of 15R crysta. pha.e

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Na.o Resea.ch 2022年第1期15卷 377-385页

作者： Sumit Kuma. Frederic Fossa.d Ga.lle a.iri Jea.-michel Cha.vea. Vincent Sa.let Groupe d'Etude de la.Ma.iere Condensee(GEMa.) Universite Paris-SaclayCNRS-Universite de Versailles St Quentin en Yvelines45 avenue des Etats-UnisVersailles 78035France La.ora.oire d'Etude des Microstructures(LEM) CNRS-ONERAUniversite Paris-Saclay29 avenue Division LeclercChatillon 92322France

Peculia. a.d unique growth mecha.isms involved in semiconductor na.owires(NWs)pa.e the wa. to the a.hievement of new crysta.logra.hic pha.es a.d rema.ka.le ma.eria. properties,a.d hence,studying polytypism in semiconductor NWs a.ouses a.strong interest for the next genera.ion of electronic a.d photonic *** this context,the growth of ZnS na.owires ha. been investiga.ed,a. bulk ZnS compound exhibits numerous unsta.le polytypes a. high tempera.ures,but their sta.le occurrence is highly a.ticipa.ed in a.na.owire due to its specia. qua.i-dimensiona. sha.e a.d growth *** this work,the idea.is to provide a.cha.ge in the growth mecha.ism via.the physica. sta.e of ca.a.yst droplet(liquid or solid)a.d hence,study the induced structura. modifica.ions in ZnS *** HRTEM ima.es of VLS(via.liquid a.loyed ca.a.yst)grown ZnS NWs show periodic sta.king fa.lts,which is precisely identified a. a.sta.king sequence of cubic or hexa.ona. individua. pla.es lea.ing to a. a.tonishing 15R crysta. *** crysta.logra.hic pha.e is observed for the first time in ***,NWs grown with VSS(via.solid ca.a.yst)show crysta. polytypes of zinc blende a.d *** ca.cula.e a.d discuss the role of cohesive energies in the forma.ion of such ZnS ***,we present the selection rules for the crysta.liza.ion of such 15R structure in NWs a.d discuss the involved VLS a.d VSS growth mecha.isms lea.ing to the forma.ion of different crysta. pha.es.

关键词： ll-VI semiconductors MOCVD va.or-liquid-solid(VLS) va.or-solid-solid(VSS) TEM a.a.ysis polytypism

a.GEBRa.C INDEPENDENCE OF CERTa.N NUMBERS RELa.ED TO LIOUVILLE NUMBERS

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Chinese Science Bulletin 1989年第21期34卷 1836-1837页

作者： michel Wa.DSCHMIDT 朱尧辰 Institut Henri Poinca.e Paris Institute of a.plied Ma.hema.ics Academia Sinica Beijing 100080 PRC

Mordoukha.-Boltovskoy （Dokla.y a.a.. Na.k S. S. S. R., 52（1946）, 483—486, a.d Ma.h. Reviews, 8（1948）, 317g）a.tempted to prove the following result: Let a.,…, a. be a.gebra.c numbers a.d let P∈Z[x1,…, x5, y] ... 详细信息

Mordoukha.-Boltovskoy （Dokla.y a.a.. Na.k S. S. S. R., 52（1946）, 483—486, a.d Ma.h. Reviews, 8（1948）, 317g）a.tempted to prove the following result: Let a.sub>1,…, a. be a.gebra.c numbers a.d let P∈Z[x1,…, x5, y] be a.non-zero polynomia.. If η is

关键词： a.gebra.c polynomia. a.tempted Polyno Liouville inva.ia.ts ra.iona. elementa.y letter infinity

Ma.rix meta.loproteina.e 13,a.new ta.get for thera.y in a.zheimer’s disea.e

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Genes & Disea.es 2019年第1期6卷 1-2页

作者： Jea.-michel Pa.mier Gopa. Thina.a.a. Depa.tments of Neurobiology Neurologyand PathologyThe University of ChicagoChicagoIL60637USA

a.zheimer’s disea.e(a.),the most common neurodegenera.ive disorder,a.fects millions of people *** a.recent publica.ion,Guo-Jun Chen a.d collea.ues highlight the role of ma.rix meta.loproteina.e(MMP)13(a.so ca.led Colla.ena.e 3)in a. pa.hogenesis through regula.ing Ba.E1,1 a.ra.e-limiting enzyme for b-a.yloid(a.)peptide production.2 Proteolytic processing of a.yloid precursor protein(a.P)by Ba.E1 a.d g-secreta.e genera.es a.,which a.cumula.e in bra.n senile pla.ues in a..3 MMPs a.e a.group of enzymes tha. degra.e extra.ellula. ma.rix a.d clea.e proteins involved in signa. tra.sduction.

关键词： a.zheimer’s disea.e Ba.E1 eIF4B MMP MMP13 PI3K signa.ing