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High-performance Quasi-Solid-State pouch Cells Enabled by in situ Solidification of a Novel polymer Electrolyte

Energy & Environmental Materials 2023年第4期6卷 15-21页

作者： Qingwen Lu Changhong Wang Danni Bao Hui Duan Feipeng Zhao Kieran doyle-Davis Qiang Zhang Rennian Wang Shangqian Zhao Jiantao Wang Huan Huang Xueliang Sun Glabat Solid-State Battery Inc. 700 Collip CircleLondon ON N6G 4X8Canada Department of Mechanical and Materials Engineering University of Western OntarioLondon ON N6A 5B9Canada China Automotive Battery Research Institute Co LtdBeijing 101407China

Conventional lithium-ion batteries(LIBs)with liquid electrolytes are challenged by their big safety concerns,particularly used in electric ***-solid-state batteries using solid-state electrolytes have been proposed to significantly improve safety yet are impeded by poor interfacial solid–solid contact and fast interface *** a compromising strategy,in situ solidification has been proposed in recent years to fabricate quasi-solid-state batteries,which have great advantages in constructing intimate interfaces and cost-effective mass *** this work,quasi-solid-state pouch cells with high loading electrodes(≥3 m Ah cm^(-2))were fabricated via in situ solidification of poly(ethylene glycol)diacrylate-based polymer electrolytes(pEGDA-pEs).Both single-layer and multilayer quasi-solid-state pouch cells(2.0 Ah)have demonstrated stable electrochemical performance over500 *** superb electrochemical stability is closely related to the formation of robust and compatible interphase,which successfully inhibits interfacial side reactions and prevents interfacial structural *** work demonstrates that in situ solidification is a facile and cost-effective approach to fabricate quasi-solid-state pouch cells with both excellent electrochemical performance and safety.

关键词： high areal capacity high-energy-density pouch cells in situ solidification poly(ethylene glycol)diacrylate-based polymer electrolyte

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夏洛克·福尔摩斯探案集之巴斯克维尔的猎犬

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丛书名：每天读一点英文名著

2013年

作者：（英）A. Conan doyle

《巴斯克维尔的猎犬》是一部充满传奇、险与智慧的侦探故事，它由英国著名侦探小说家、“英国侦探小说之父”阿瑟·柯南·道尔编著，在充滞雾气的伦敦贝克街上，住着一位富有正义感的侦探福尔摩斯……

ISBN: (纸本)9787561179840;9787561178102

关键词：小说集对照读物侦探小说英语现代英国短篇小说汉语

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Vacuole Integrity Maintained by DUF300 proteins Is Required for Brassinosteroid Signaling Regulation

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Molecular plant 2018年第4期11卷 553-567页

作者： Qinsong Liu Thomas Vain Corrado Viotti Siamsa M, doyle Danuse Tarkowska Ondrej Novak Cyril Zipfel Folke Sitbon Stephanie Robert Daniel Hofius Department of plant Biology Uppsala BioCenter Swedish University of Agricultural Sciences (SLU) and Linnean Center for Plant Biology PO Box 7080 750 07 Uppsala Sweden Department of Forest Genetics and plant physiology Umea Plant Science Centre Swedish University of Agricultural Sciences (SLU) 90183 Umea Sweden Umea plant Science Centre Umea University 90187 Umea Sweden Institute of Biochemistry and Biology Plant Physiology University of Potsdam 14476 Potsdam Germany Laboratory of Growth Regulators Centre of the Region Hana for Biotechnological and Agricultural Research institute of Experimental Botany ASCR and Palacky University 783 71 Olomouc Czech Republic The Sainsbury Laboratory Norwich Research Park Norwich NR4 7UH UK These authors contributed equally to this article. present addresses: Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education) College of Life Science China West Normal University Nanchong 637009 Sichuan China Institut de Biologie Moleculaire des plantes du CNRS IBMP-CNRS UPR2357 12 rue du General Zimmer 67084 Strasbourg France

Brassinosteroid （BR） hormone signaling controls multiple processes during plant growth and development and is initiated at the plasma membrane through the receptor kinase BRASSINOSTEROID INSENSITIVE1 （BRI1） together with co-receptors such as BRI1-ASSOClATED RECEpTOR KINASE1 （BAK1）. BRI1 abun- dance is regulated by endosomal recycling and vacuolar targeting, but the role of vacuole-related proteins in BR receptor dynamics and BR responses remains elusive. Here, we show that the absence of two DUF300 domain-containing tonoplast proteins, LAZARUS1 （LAZl） and LAZl HOMOLOG1 （LAZlH1）, causes vacuole morphology defects, growth inhibition, and constitutive activation of BR signaling. Intriguingly, tonoplast accumulation of BAK1 was substantially increased and appeared causally linked to enhanced BRI1 trafficking and degradation in lazl lazlhl plants. Since unrelated vacuole mutants exhibited normal BR responses, our findings indicate that DUF300 proteins play distinct roles in the regulation of BR signaling by maintaining vacuole integrity required to balance subcellular BAK1 pools and BR receptor distribution.

关键词： brassinosteroid signaling vacuole integrity DUF300 proteins tonoplast Arabidopsis

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夏洛克·福尔摩斯历险记

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丛书名：每天读一点英文名著

2013年

作者：（英）A. Coana doyle

本书收录了红发会、斑点带子案、铜山毛榉案几部作品。

ISBN: (纸本)9787561179864;9787561178140

本书收录了红发会、斑点带子案、铜山毛榉案几部作品。

关键词：小说集对照读物侦探小说英语现代英国汉语

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Changes in the patient-Reported Outcomes Measurement Information System (pROMIS) scores following sacral neuromodulation for lower urinary tract symptoms

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Current Urology 2024年第4期18卷 318-322页

作者： Elaine Minerva Jaworski Derrick J.Sanderson Matthew Gevelinger paula J.doyle School of Medicine and Dentistry University of RochesterRochesterNYUSA Department of Obstetrics and Gynecology School of Medicine and DentistryUniversity of RochesterRochesterNYUSA Department of Obstetrics and Gynecology Department of UrologySchool of Medicine and DentistryUniversity of RochesterRochesterNYUSA

Background Sacral neuromodulation (SNM) treatment of refractory urinary symptoms is associated with quality of life improvements using disease-specific instruments. There is a paucity of information relating universal health outcomes to effective treatment of urinary symptoms. The objective was to analyze changes in patient-Reported Outcomes Measurement Information System (pROMIS) item-bank scores following SNM for treating refractory lower urinary tract symptoms (LUTS).Materials and methods This is a sub-analysis collected from an institutional review board approved, retrospective chart review evaluating changes between pre- and post-procedure pROMIS scores in subjects undergoing successful SNM implantation for refractory LUTS at a multidisciplinary adult continence clinic. The difference between pre- and post-procedure pROMIS scores was compared via two-sided Wilcoxon signed-rank test, with p public insurance (62.07%). The median age was 63years and body mass index was 33.2kg/m2. procedure indications included urinary urge incontinence (83%), mixed urinary incontinence (10%), retention (17.24%), and overactive bladder (3%). pain Interference and Depression scores had a nonsignificant improvement from 64.2 (ranging 58.9–67.5) to 60.75 (ranging 55.2–67.2), p = 0.21, and 55.2 (ranging 51.5–59.9) to 53.4 (ranging 49.5–61.1), p = 0.33, respectively. Median physical Function scores demonstrated nonsignificant worsening following implantation from 38.0 (ranging 34.7–40.9) to 36.1 (ranging 33.1–40.8) (p = 0.25). Twenty-one subjects (72%) reported an improvement in at least 1 pROMIS item-bank with 6 subjects (21%) reporting no improvement in any of the *** Treatment of refractory LUTS with SNM resulted in no statistically significant changes in the pROMIS item-banks of physical Function, pain Interference, or Depr

关键词： Overactive bladder patient reported outcomes Sacral neuromodulation Urinary retention

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An assessment of African lion panthera leo sociality via social network analysis： prerelease monitoring for an ex situ reintroduction program

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Current Zoology 2017年第3期63卷 301-311页

作者： Emma J. DUNSTON Jackie ABEL Rebecca E. doyle Jacqui KIRK Victoria B. HILLEY Andrew FORSYTH Emma JENKINS Rafael FREIRE School of Animal and Veterinary Sciences Charles Sturt University Wagga Wagga NSW 2678 Australia Social and Conservation psycology Coventry University Coventry CV1 5FB UK African Lion & Environmental Research Trust Melrose Farm Livingstone 23345 Zambia Animal Welfare Science Centre The University of Melbourne Parkville Victoria 3010 Australia African Lion & Environmental Research Trust Antelope Park Gweru Midlands Zimbabwe Siyafunda The Greater Makalali Private Game Reserve Harmony 27 Hoedspruit 0895 South Africa

The wild population of the African lion panthera leo continues to decline, requiring alternate conservation programs to be considered. One such program is ex situ reintroduction. prior to release, longterm monitoring and assessment of behavior is required to determine whether prides and coalitions behave naturally and are sufficiently adapted to a wild environment. Social network analysis （SNA） can be used to provide insight into how the pride as a whole and individuals within it, function. Our study was conducted upon 2 captive-origin prides who are part of an ex situ reintroduction program, and 1 wild pride of African lion. Social interactions were collected at all occurrence for each pride and categorized into greet, social grooming, play, and aggression. Betweenness centrality showed that offspring in each pride were central to the play network, whereas degree indicated that adults received （indegree） the greatest number of overall social interactions, and the adult males of each pride were least likely to initiate （outdegree） any interactions. Through the assessment of individual centrality and degree values, a social keystone adult female was identified for each pride. Social network results indicated that the 2 captive-origin prides had formed cohesive social units and possessed relationships and behaviors comparable with the wild pride for the studied behaviors. This study provided the first SNA comparison between captive-bred origin and a wild pride of lions, providing valuable information on individual and pride sociality, critical for determining the success of prides within an ex situ reintroduction program.

关键词： African lion panthera leo conservation ex situ reintroduction social interactions.

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EXpRESSION OF BCRp GENE IN THE NORMAL LUNG TISSUE AND LUNG CANCER

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Chinese Journal of Cancer Research 2001年第1期13卷 22-26页

作者：毛友生 Austin doyle Weidong Yang Yuetong Wei Mark J. Krasna Douglas D. Ross Greenebaum Cancer Center University of Maryland Medical School

Objective: To investigate the expression of novel multidrug resistance transporter (BCRp gene) from human MCF-7/AdrVp breast cancer cells in normal lung tissue and non-small lung cancer tissue. Methods: RNA was extracted immediately from fresh normal lung tissue and viable tumor tissue harvested from surgically resected specimens of non-small cell lung cancer patients. cDNA of BCRp gene was prepared by RT-pCR and was then amplified by pCR. cDNA products from those specimens were transferred to blotting membrane through electrophoresis and transferring technique and southern blot hybridization was eventually performed to detect the expression of BCRp gene. Results: RNA were extracted from 8 tumor tissue alone and 12 pairs of tumor tissue and normal lung tissue harvested from the same lung. Four patients’ RNA samples with poor quality due to degrading were discarded. cDNA products of BCRp gene were obtained by RT-pCR and were then amplified by pCR in the remain 16 patients’ RNA samples. Through southern blot hybridization, BCRp gene was found to be slightly expressed in various amounts in all normal lung tissue (10/10) and only in a half of tumor tissue samples (8/16). Conclusion: BCRp gene is slightly expressed in different amount in all normal lung tissue and only in a half of tumor tissue of non-small cell lung cancer patients. It is possible to induce it’s overexpression and to develop multidrug resistance during chemotherapy if using anthracycline anticancer drugs.

关键词： Multidrug resistance BCRp gene Non-small cell lung cancer Chemotherapy

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