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Plastome characteristics of Cannabaceae

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Plant Diversity 2018年第3期40卷 127-137页

作者： Huanlei Zhang Jianjun Jin michael J.moore Tingshuang Yi Dezhu Li Germplasm Bank of Wild Species Kunming Institute of Botany Chinese Academy of Sciences Kunming College of Life Sciences University of Chinese Academy of Sciences Department of Biology Oberlin College

Cannabaceae is an economically important family that includes ten genera and ca. 117 accepted *** explore the structure and size variation of their plastomes, we sequenced ten plastomes representing all ten genera of Cannabaceae. Each plastome possessed the typical angiosperm quadripartite structure and contained a total of 128 genes. The Inverted Repeat(IR) regions in five plastomes had experienced small expansions(330 e983 bp) into the Large Single-Copy(LSC) region. The plastome of Chaetachme aristata has experienced a 942-bp IR contraction and lost rpl22 and rps19 in its IRs. The substitution rates of rps19 and rpl22 decreased after they shifted from the LSC to IR. A 270-bp inversion was detected in the Parasponia rugosa plastome, which might have been mediated by 18-bp inverted repeats. Repeat sequences, simple sequence repeats, and nucleotide substitution rates varied among these *** markers with more than 13% variable sites and 5% parsimony-informative sites were identified, which may be useful for further phylogenetic analysis and species identification. Our results show strong support for a sister relationship between Gironniera and Lozanell(BS ? 100). Celtis, CannabisHumulus, Chaetachme-Pteroceltis, and Trema-Parasponia formed a strongly supported clade, and their relationships were well resolved with strong support(BS ? 100). The availability of these ten plastomes provides valuable genetic information for accurately identifying species, clarifying taxonomy and reconstructing the intergeneric phylogeny of Cannabaceae.

关键词： Plastome IR expansion/contraction Repeats SSR Sequence divergence Phylogenomics

Game development essentials. Game industry career guide

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Evidence base of randomized controlled trials and guideline recommendations of patent Traditional Chinese Medicines for uncomplicated acute lower respiratory tract infections in adults

丛书名： Game development essentials

2010年

作者： michael E moore Jeannie Novak

来源：畅想之星图书光盘版（南... 评论

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Journal of Traditional Chinese Medicine 2018年第4期38卷 490-503页

作者： Xia Ruyu Hu Xiaoyang Wang Di Wang Ying Merlin Willcox Liu Jianping michael moore Andrew Flower Li Xun Lily Lai Hu Ruixue Wen Lingzi Zhang Lishan Wang Qi Fei Yutong Centre for Evidence-Based Chinese Medicine Beijing University of Chinese Medicine Primary Care and Population Sciences University of Southampton Respiratory Department Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine Respiratory Department Dongfang Hospital Affiliated to Beijing University of Chinese Medicine

OBJECTIVE:To compare clinical practice guideline recommendations on the use of oral patent Traditional Chinese Medicines(PTCMs) for uncomplicated acute lower respiratory tract infections(ALRTIs)in adults with the existing evidence using results of a systematic review of randomized controlled trials(RCTs).METHODS:A systematic review on RCTs and a systematic review of current guidelines on orally taken PTCMs for uncomplicated ALRTIs were *** Med,Cochrane Library,EMBASE and four Chinese databases were searched from inception to September 2016 for RCTs testing orally taken PTCMs for uncomplicated ALRTIs(excluding pneumonia).Two reviewers independently screened each study,extracted study data,and assessed risk of *** were resolved through discussion or by consultation with a third *** practice guidelines for uncomplicated ALRTIs containing PTCM recommendations were identified and quality *** quality of pooled evidence of the RCTs and the guidelines was assessed with GRADE and AGREE Ⅱ *** consistency of the evidence base in RCTs and the guideline recommendations were then ***:For the systematic review of RCTs,4810 papers were identified,among which 29 RCTs(5093 patients) were included in the *** compared to placebo increased the effective treatment rate of cough(3 trials,949 patients,risk ratio(RR) 2.50,1.16 to 5.43;low certainty);improved assessment of global health(3 trials,948 patients,RR1.70,1.44 to 2.01;low certainty);and increased the effective rate of specific symptom relief(1 trial,478 patients,RR 4.01,2.76 to 5.81;moderate certainty).21 trials(3432 patients) compared effects of different *** the guideline evaluation,29 PTCMs were recommended for the use of uncomplicated ALRTIs,of which27 had no supportive evidence from ***:The evidence base of PTCMs for uncomplicated ALRTIs is weak and the guideline recommendations were based on almost no clinical trial evidence.

关键词： Traditional Chinese Medicine Acutelower respiratory tract infections Antibiotic Ay-stematic review Guideline

Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant ‘tree of life’

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National Science Review 2021年第4期8卷 66-77页

作者： Yongzeng Zhang Tao Deng Lu Sun Jacob B.Landis michael J.moore Hengchang Wang Yuehua Wang Xiaojiang Hao Jijun Chen Shenghong Li Maonian Xu Pema-Tenzin Puno Peter H.Raven Hang Sun CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of Botany Chinese Academy of Sciences University of the Chinese Academy of Sciences Department of Botany and Plant Sciences University of California Riverside School of Integrative Plant Science Section of Plant Biology and the L.H.Bailey HortoriumCornell University Department of Biology Oberlin College CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Chinese Academy of Sciences School of Life Science Yunnan University State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of Sciences Pharmaceutical Sciences University of Iceland Missouri Botanical Garden

To evaluate the phylogenetic patterns of the distribution and evolution of plant secondary metabolites(PSMs), we selected 8 classes of PSMs and mapped them onto an updated phylogenetic tree including 437 families of seed plants. A significant phylogenetic signal was detected in 17 of the 18 tested seed-plant clades for at least 1 of the 8 PSM classes using the D statistic. The phylogenetic signal, nevertheless, indicated weak clustering of PSMs compared to a random distribution across all seed plants. The observed signal suggests strong diversifying selection during seed-plant evolution and/or relatively weak evolutionary constraints on the evolution of PSMs. In the survey of the current phylogenetic distributions of PSMs, we found that multiple origins of PSM biosynthesis due to external selective forces for diverse genetic pathways may have played important roles. In contrast, a single origin of PSMs seems rather uncommon. The distribution patterns for PSMs observed in this study may also be useful in the search for natural compounds for medicinal purposes.

关键词： secondary metabolites phylogenetic tree phylogenetic signal co-diversification evolution bioprospecting seed plants

Reservoir construction from the Newberry Volcano EGS Demonstration

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Journal of Groundwater Science and Engineering 2014年第3期2卷 1-7页

作者： Trenton T Cladouhos Susan Petty Yini Nordin michael moore Kyla Grasso Matt Uddenberg michael W Swyer Alta Rock Energy Inc.

The Newberry Volcano EGS Demonstration in central Oregon tests recent technological advances designed to reduce the cost of power generated by EGS in a hot,dry well(NWG 55-29) drilled in 2008. An EGS reservoir was created by injecting large volumes of cold water,causing existing fractures to slip in shear(known as hydroshearing) generating the seismic waves that can be used to map fracture location and size. At the Newberry Demonstration the final injectivity ranged between 1.4 and 1.7 L/s/MPa a ~6x improvement over the initial injectivity of the well. The injectivity improvement and seismic analysis indicate that previously impermeable fractures were enhanced during the NWG 55-29 stimulation.

关键词： EGS Stimulation Hydroshearing Microseismicity

Use of rotablation to rescue a “fractured” micro catheter tip: A case report

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World Journal of Cardiology 2019年第7期11卷 189-194页

作者： Mohammad Alkhalil Conor McQuillan michael moore Mark S.Spence Colum Owens Cardiology Department Royal Victoria HospitalBelfast BT12 6BAUnited Kingdom Cardiology Department Craigavon Area HospitalPortadown BT63 5QQUnited Kingdom

BACKGROUND High-speed rotational atherectomy (HSRA) is most commonly used to modify calcified coronary artery lesions to facilitate stent deployment and expansion. The use of HSRA as an emergency rescue technique to release a fractured microcatheter has not been described. We report the use of HSRA in a case of a fracture trapped corsair tip that was impeding coronary flow causing a ST elevation myocardial infarct. CASE SUMMARY A 79 years old male was scheduled for elective percutaneous coronary intervention (PCI) to his left anterior descending artery (LAD). Given its calcific nature, a decision was made for upfront rotablation. During procedural preparations, the tip of an employed micro-catheter was separated from the shaft resulting in obstructing coronary flow and ST-segment elevation. The consensus was for an attempt bail out PCI strategy. A rotafloppy wire was advanced to the distal LAD using a corsair micro-catheter which was placed proximal to the occlusion site. Modification of the mid LAD segment was performed, resulting in mobilising the corsair tip, and deflecting it to a small diagonal branch. Following serial predilation, the procedure was completed using two overlapping drug eluting stents, jailing the corsair tip in the diagonal branch. The patient made uneventful recovery and was clinically stable at one year follow up. CONCLUSION HSRA may be offered as a bailed-out strategy to rescue fractured and jailed micro-catheter tip in high risk surgical cases.

关键词： Micro-catheter Rotational atherectomy Calcification Case report

血管腔内超声辅助盘圈关闭婴幼儿动脉导管未闭的临床研究

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中国超声医学杂志 2000年第4期16卷 25-27页

作者：舒先红,TonyM Chou,Eitetsu Ko,Krishnanketty Sudhir,michael Brook,Phillip moore 上海医科大学中山医院!上海市心血管病研究所 200032 美国加州大学旧金山分校心血管病研究所美国加州大学旧金山分校心血管病研究所美国加州大学旧金山分校心血管病研究所美国加州大学旧金山分校心血管病研究所美国加州大学旧金山分校心血管病研究所

目的 :本研究旨在评价血管腔内超声辅助盘圈关闭婴幼儿动脉导管未闭术的安全性和可行性。方法 :对 9例动脉导管未闭婴幼儿患者在血管腔内超声辅助下进行盘圈关闭术。结果 :所有 9例患者都成功地进行了血管腔内超声检查 ,无一例发生并发... 详细信息

目的 :本研究旨在评价血管腔内超声辅助盘圈关闭婴幼儿动脉导管未闭术的安全性和可行性。方法 :对 9例动脉导管未闭婴幼儿患者在血管腔内超声辅助下进行盘圈关闭术。结果 :所有 9例患者都成功地进行了血管腔内超声检查 ,无一例发生并发症。血管腔内超声显示动脉导管为一单层中等回声的管状结构 ,管壁厚度均匀。血管腔内超声测量的平均动脉导管最小内径为 3.0 8± 0 .71mm。 8例患者的盘圈关闭术成功 ,一例患者因动脉导管直径太大(5 .6 1mm)而未能成功。术后随访未发现残余分流 ,盘圈移位以及主动脉或肺动脉阻塞。结论 :血管腔内超声能够安全有效地评价婴幼儿动脉导管未闭 ,为盘圈关闭术提供了血管造影和超声心动图所不能得到的信息 ,从而帮助选择大小适宜的盘圈 ,减小盘圈栓塞和移位的危险性 ,提高手术的成功率。

关键词：盘圈关闭术动脉导管未闭血管腔内超声血管造影超声心动图

Sentinel lymph node mapping for malignant melanoma of the external auditory canal

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World Journal of Surgical Procedures 2015年第1期5卷 173-176页

作者： Joel Franco Lauren A Hansen Richard T Miyamoto Mark Tann michael G moore St.Louis University School of Medicine Department of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indiana University School of Medicine Department of Radiology and Imaging Services

We describe a novel technique for sentinel lymph node mapping and biopsy of a primary cutaneous malignant melanoma in the medial portion of the external auditory canal. The approach is illustrated through a case report and technical description of a procedure performed under general anesthesia on a 19-year-old female patient. Due to the hidden and sensitive location of the primary tumor in the medial external auditory canal, the lymphoscintigraphy injection had to be performed by the surgeon immediately prior to the resection of her c T2 a N0M0 lesion. Final pathology revealed clear margins at the primary site resection and 2 intraparotid sentinel lymph nodes with microscopic foci of metastatic malignant melanoma, which led to further surgical management. A completion left parotidectomy and neck dissection yielded no additional metastatic disease in the fifty-five nodes that were evaluated. Using this technique, sentinel lymph node mapping and biopsy accurately predicted the highest risk lymph nodes for the primary lesion of the medial portion of the external auditory canal.

关键词： Malignant melanoma External auditory canal Head and neck Sentinel lymph node biopsy Sentinel lymph node mapping

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采用可编程串行接口设计背板

电子产品世界 2001年第9期8卷 61-63页

作者： michael T.moore Cypress半导体公司

在网络路由器或交换机以及企业存储设备等系统中的高速背板中,通信系统正在使速度限制超越传统的1Gbps大关.PCI或VME之类的共享总线拓朴结构曾用于背板应用,然而,它们在可伸缩性、带宽和距离方面受到限制,即使最新的PCI-X也只能在刚过1G... 详细信息

在网络路由器或交换机以及企业存储设备等系统中的高速背板中,通信系统正在使速度限制超越传统的1Gbps大关.PCI或VME之类的共享总线拓朴结构曾用于背板应用,然而,它们在可伸缩性、带宽和距离方面受到限制,即使最新的PCI-X也只能在刚过1Gbyte/s的速率下使用.共享总线拓朴主要的限制因素在于高的I/O和有限的距离.由于任何一条引线或连线的损坏都将造成整个接口故障,所以可靠性也是共享总线的一个问题.共享总线的最大有效距离是18英寸.

关键词：串行接口背板通信网网络设备