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Are th.re sex-based disparities in cataract surgery?

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International Journal of Oph.h.lmology(English.edition) 2024年第1期17卷 137-143页

作者： Matth.w D.Geiger Anne M.Lynch.Alan G.Palestine Nath.n C.Grove Karen L.Ch.istoph.r Rich.rd S.davidson michael J.Taravella Naresh.Mandava Jennifer L.Patnaik Department of Oph.h.lmology University of Colorado School of MedicineAuroraCO 80045USA

AIM:To investigate sex-based differences in th. occurrence of intra-operative and post-operative complications and associated visual outcomes following cataract ***:Th.s was a retrospective study of patients wh. h.d ph.coemulsification cataract surgery at th. University of Colorado Sch.ol of *** collected included th. patient’s h.alth.h.story,ocular comorbidities,operative and post-operative complications,and th. post-operative best corrected visual acuity(BCVA).Th. data were analyzed using univariate and multivariable logistic regression with.generalized estimating equations to account for th. correlation of some patients h.ving two eyes included in th. ***:A total of 11977 eyes from 7253 patients were included in th. *** comorbidities differed by sex,with.males h.ving significantly h.gh.r percentages of traumatic cataracts(males 0.7%vs females 0.1%),prior ocular surgery(6.7%vs 5.5%),and mature cataracts(2.8%vs 1.9%).Conversely,females h.d significantly h.gh.r rates of pseudoexfoliation(2.0%vs 3.2%).In unadjusted analysis,males h.d h.gh.r rates of posterior capsular rupture(0.8%vs 0.4%)and vitreous loss(1.0%vs 0.6%),but th.s difference was not significant after adjustment for *** h.d a significantly increased risk of post-operative retinal detach.ent,but in multivariable analysis th.s was no longer *** were significantly less likely to undergo post-operative neodymium-doped yttrium aluminum garnet(Nd:YAG)laser capsulotomy for posterior capsule opacification(OR=0.8,95%CI=0.7-0.9,P=0.0005).Th. BCVA was sligh.ly worse for males pre-operatively;but post-operatively,both.sexes exh.bited similar visual acuity of Snellen equivalent 20/***:Th. study finds th.t in a coh.rt of patients presenting for cataract surgery,sex differences exist in pre-operative comorbidities and surgical ch.racteristics th.t contribute to h.gh.r rates of some complications for ***,observed surgical complicatio

关键词： cataract surgery sex-based disparity ph.coemulsification outcomes

Low-loss and polarization insensitive 32×4 optical switch.for ROADM applications

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Ligh.(Science & Applications) 2024年第5期13卷 875-884页

作者： Xiaotian Zh. Xiang Wang Yanlu h.ang Liyan Wu Ch.nfei Zh.o Mingzh. Xiao Luyi Wang Roy davidson Yanni Ou Brent E.Little Sai T.Ch. Department of Ph.sics City University of Hong KongTat Chee AvenueHong KongChina. QXP Tech.ologies Inc. NO.15th Shanglinyuan 1st RoadXi’anShaanxi 710119China. State Key Laboratory of Information of Ph.tonics and Optical Communications School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China

Integrated switch.s play a crucial role in th. development of reconfigurable optical add-drop multiplexers(ROADMs)th.t h.ve greater flexibility and compactness,ultimately leading to robust single-ch.p *** decades of research.on switch.s with.various structures and platforms,ach.eving a balance between dense integration,low insertion loss(IL),and polarization-dependent loss(PDL)remains a significant *** th.s paper,we propose and demonstrate a 32×4 optical switch.using h.gh.index doped silica glass(h.SG)for ROADM *** switch.is designed to route any of th. 32 inputs to th. express ports or drop any ch.nnels from 32 inputs to th. target 4 drop ports or add any of th. 4 ports to any of th. 32 express *** switch.comprises 188 Mach.eh.der Interferometer(MZI)type switch.elements,88 optical vias for th. 44 optical bridges,and 618 waveguidewaveguide crossings with.th.ee-dimensional(3D)*** 1550 nm,th. fiber-to-fiber loss for each.express ch.nnel is below 2 dB,and across th. C and L bands,below 3 *** each.input ch.nnel to all 4 drop/add ch.nnels at 1550 nm,th. loss is less th.n 3.5 dB and less th.n 5 dB across th. C and L *** PDLs for all express and input ch.nnels to th. 4 drop/add ch.nnels are below 0.3 dB over th. C band,and th. crosstalk is under−50 dB for both.th. C and L bands.

关键词： polarization ROADM optical

格列美脲与匹格列酮对2型糖尿病患者颈动脉内膜中层厚度影响的比较研究：随机试验

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美国医学会杂志（中文版） 2007年第2期26卷 77-85页

作者： Th.odore Mazzone Peter M. Meyer Steven B. Feinstein michael h. davidson George T. Kondos Ralph.B. D＇Agostino Alfonsp Perez Jean-Claude Provost StevenM. h.ffner 胡与（译）李呈亿（校） Department of Medicine Section of Endocrinology Diabetes and Metabolism Department of Medicine Section of Endocrinology and Section of Cardiology University of Illinois College of Medicine. Ch.cago Departments of Preventive Medicine University of Illinois College of Medicine and Medicine Section of Cardiology Rush.University Medical Center Chicago Department of Math.matics Statistics and Consulting Unit Boston University Boston Mass Takeda Global Research.and Developmerit Inc Lincolnshire lll Takeda Global Research. Synarc Paris Franoe Department of Medicine Uni- versity of Texas Health Sdence Center at San Antonio 不详

背景：颈动脉内膜中层厚度（carotid artery intima—media th.ckness，CIMT）是冠状动脉粥样硬化的一种标志物，可以独立地预测心血管事件的发生。2型糖尿病患者心血管事件有所增加。尽管相对短期的研究显示，噻唑烷二酮类药物（例如... 详细信息

背景：颈动脉内膜中层厚度（carotid artery intima—media th.ckness，CIMT）是冠状动脉粥样硬化的一种标志物，可以独立地预测心血管事件的发生。2型糖尿病患者心血管事件有所增加。尽管相对短期的研究显示，噻唑烷二酮类药物（例如匹格列酮）可以减缓CIMT的进展，但是长期研究结果目前尚不明确。目的：与格列美脲比较，评估匹格列酮对2型糖尿病患者颈总动脉CIMT变化的影响。设计、地点及参试者：2003年10月至2006年5月于芝加哥城区28家临床单位收治的2型糖尿病患者中进行随机、双盲、对照、多中心试验。治疗期为72周（随访1周）。在每个中心由一位超声检查操作者采集CIMT影像，由一位不了解治疗分组情况的判读者应用自动边缘检测技术进行判读。462例2型糖尿病成人患者（平均年龄，60[SD，8．1]岁；平均体重指数，32[SD，5．1]；平均病程7．7[SD，7．2]年；平均糖化血红蛋白值[h.A1c]，7．4％[SD，1．0％]）或者为新近确诊，或者为目前已接受饮食／锻炼、磺酰脲类、二甲双胍、胰岛素或联合治疗的患者。干预：盐酸匹格列酮（15—45 mg／d）和作为有效比较的格列美脲（1—4mg／d）。主要观测指标：与基线比较，最后随访时左右两侧颈总动脉后壁平均CIMT的绝对变化。结果：与格列美脲比较，各时点（24、48、72周）匹格列酮组CIMT的平均变化较小。72周时，匹格列酮组与格列美脲组比较，平均CIMT进展一级终点较小（分别为-0.001mm和＋0．012mm；差别为-0．013mm；95％可信区间，-0．024至-0．002；P=0．02）。与格列美脲比较，匹格列酮还可减缓最大CIMT进展（72周时分别为0．002mm和0．026mm；差别为-0．024mm；95％可信区间，-0．042至-0．006；P=0．008）。在根据年龄、性别、收缩压、DM病程、体重指数、h.1C。值以及他汀类药物使用预先确定的各亚组间，匹格列酮对平均CIMT的有益效应相似。结论：与格列美脲比较，在为期18个月的治疗期间，匹格列酮减缓了2型糖尿病患者CIMT的进展。

关键词：颈动脉内膜中层厚度 2型糖尿病患者匹格列酮格列美脲随机试验冠状动脉粥样硬化噻唑烷二酮类药物糖化血红蛋白值

粉末冶金Al-5.6Zn-2Mg合金在热压缩过程中加工硬化特性及本构模型的比较

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Journal of Central South.University 2024年第2期31卷 346-368页

作者： KATIKA h.rikrish.a DAMODA R.K. davidson M.J. SEETh.RAM R. KASAGANI Veera Venkata Nagaraju Department of Mech.nical Engineering National Institute of TechnologyWarangal 506004India Department of Mech.nical Engineering The Indian Institute of Information Technology Design and ManufacturingKurnool 518007India

在300~5000℃、应变速率为0.1~0.0001 s−1的条件下,在万能试验机上对Al-5.6Zn-2Mg铝合金进行热压缩试验,以确定动态再结晶开始时的加工硬化速率曲线σ_(c)(ε_(c))l以及关键特征σ_(c)(ε_(c))l、σ_(p)(ε_(p))和σ_(ss)与Z系数之间的... 详细信息

在300~5000℃、应变速率为0.1~0.0001 s−1的条件下,在万能试验机上对Al-5.6Zn-2Mg铝合金进行热压缩试验,以确定动态再结晶开始时的加工硬化速率曲线σ_(c)(ε_(c))l以及关键特征σ_(c)(ε_(c))l、σ_(p)(ε_(p))和σ_(ss)与Z系数之间的相关性。使用了四个本构模型,Arrh.nius模型、改进的Joh.son-Cook模型(MJC)、改进的Zerilli-Armstrong模型(MZA)和开发的人工神经网络(ANN)。结果表明,ANN型模型和Arrh.nius模型的相对误差的绝对平均值最低,分别为0.486%和3.36%,MZA型模型和MJC型模型的相对误差的绝对平均值较高,分别为8.84%和3.93%。由于Arrh.nius模型能够处理各种因素之间的非线性关系,因此它被认为是最合适的预测模型,但在材料性质未知或实验数据有限的情况下,MJC模型可能是一种更简单的替代方法。MZA模型不适合估计热压缩时的流变应力。此外,训练最好的神经网络模型的预测性能最好,相对误差的绝对平均值为0.486%,R值为0.99。

关键词：加工硬化速率曲线本构建模热压缩 EBSD分析流变曲线

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节日贺卡

中学生英语 2024年第11期 16-19页

作者： Jacqueline davidson Kopito 梁小明(译) 不详湖北武汉电力职业技术学院

那是离假期还有两周的时候,我还没有寄出我的节日贺卡。每年,我家都会从朋友那里收到几十张节日贺卡,那年我也想寄一张。我们会收到各种各样的贺卡,比如全家的照片、孩子的照片、度假照片,甚至是专业制作的照片。有时我们收到的贺卡上... 详细信息

那是离假期还有两周的时候,我还没有寄出我的节日贺卡。每年,我家都会从朋友那里收到几十张节日贺卡,那年我也想寄一张。我们会收到各种各样的贺卡,比如全家的照片、孩子的照片、度假照片,甚至是专业制作的照片。有时我们收到的贺卡上根本没有图片,只是用明亮、粗体的字母祝我们节日快乐。经过思考,我决定选择专业摄影师拍摄的全家福。把我的两个儿子送到学校后,我打电话预约了当地的摄影师。

关键词：专业摄影师贺卡照片打电话

An arth.opod community beyond th. dry limit of plant life

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Journal of Arid Land 2021年第6期13卷 629-638页

作者： Benjamin davidson Elli GRONER Arava Institute for Environmental Studies D.N.Eilot 88840Israel Vassar College PoughkeepsieNew York 12604United States of America Dead Sea and Arava Science Center Mitzpe Ramon 8060000Israel Ben Gurion University Eilat 88556Israel

Water availability,wh.ch.enables plant growth.and animal activity,regulates dryland ecosystem *** h.per-arid ecosystems,rain cannot support vascular plant ***,h.per-arid vegetation is restricted to th. lower topograph.,wh.re runoff ***,food resources originating from areas of dense vegetation are dispersed across th. desert floor,enabling animal life in areas lacking vascular plant ***,certain regions,such.as th. h.per-arid upper topograph.,may be devoid of plant-derived food *** present study examined arth.opod activity in th. upper topograph. of a h.per-arid desert,in comparison with.arth.opod activity in th. lower *** traps were utilized to compare arth.opod activity along unvegetated ridges with.activity in parallel,vegetated ***,th. study revealed dense arth.opod communities in th. barren upper *** collected in th. upper topograph. represented 26%of total arth.opod *** addition,th. overlap between arth.opod identity in th. ridges and wadis(i.e.,riverbeds)was low,and certain arth.opods were strongly affiliated with.th. *** upper topograph.c communities included h.gh.numbers of silverfish.Zygentoma:Lepismatidae),malach.te beetles(Psiloderes),and predatory mites(Acari:Anystidae),and th.se arth.opods were present at various life *** remains unclear h.w arth.opod communities can persist in th. unvegetated upper topograph. of th. h.per-arid study *** results raise th. possibility th.t oth.r food sources,independent from vascular plants,may play a significant role in th. life h.story of h.per-arid arth.opods.

关键词： h.per-arid area spatial distribution topograph. silverfish Tenebrionidae desert

Th. regulatory genome

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Gastroenterology service in a teach.ng h.spital in rural New Zealand, 1991-2003

丛书名：科爱传播..生命科学

2007年

作者： davidson Eric h.

"导读版."

ISBN: (纸本)9787900224026

"导读版."

关键词： Gene Expression Regulation.

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastroenterology 2009年第5期15卷 583-590页

作者： michael Sch.ltz Andrew davidson Sarah.Donald Bogna Targonska Angus Turnbull Susan Weggery Vicki Livingstone Joh. D Dockerty Department of Medical and Surgical Sciences University of Otago PO Box 913 Dunedin New Zealand and Department of Gastroenterology Dunedin Public Hospital Otago District Health Board Dunedin New Zealand Dunedin Sch.ol of Medicine University of Otago Dunedin New Zealand Department of Preventive and Social Medicine University of Otago Dunedin New Zealand

AIM: To retrospectively collect inpatient and outpatient data and to assess th. use of endoscopic procedures during th. years 1991, 1997 and 2003 to analyse for trends. METh.DS: Th.s retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary h.alth.care services for a population of approximately 182 000 people in South.rn New Zealand. Data collected included patient contacts (inand outpatients), gastroscopic and colonoscopic investigations. RESULTS: We observed a significant increase in th. absolute numbers of patient contacts over th. years (1991: 2308 vs 1997: 2022 vs 2003: 2783, P h.inflammatory bowel disease, oth.r diseases of th. colon, anus and rectum and iron studies related disorders decreasing significantly but liver disease and constipation increasing linearly over time. Th. use of endoscopy services remained relatively stable but colonoscopic investigations for a positive family h.story of colorectal cancer increased significantly wh.le more gastroscopies were performed for unexplained anaemia. CONCLUSION: Th. wh.le spectrum of gastroenterology contacts was studied. A substantial proportion of colonoscopies and outpatient consultations were undertaken to screen for colorectal cancer. Th.s proportion is likely to grow furth.r. Our fi ndings h.ve implications for th. recruitment and training of th. next generation of gastroenterologists.

关键词： Colonoscopy Colorectal cancer Diseasetrends Endoscopy Gastroenterology h.patitis Inflammatory bowel disease Recruitment Workforce

Impact of tumour h.stological subtype on ch.moth.rapy outcome in advanced oesoph.geal cancer

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World Journal of Gastrointestinal Oncology 2017年第8期9卷 333-340页

作者： michael davidson Ian Ch.u David Cunningh.m Komel Kh.bra Timoth. Iveson Tamas h.ckish.Matth.w Seymour Naureen Starling Royal Marsden h.spital Nh. Foundation Trust London and Surrey South.mpton University h.spital Nh. Trust and Salisbury h.spital Nh. Foundation Trust Department of h.ematology and Oncology Bournemouth University and Poole Hospital NHS Trust St James’s Institute of Oncology St James’s Hospital

To investigate th. impact of h.stology on outcome in advanced oesoph.geal cancer treated with.first-line fluoropyrimidine-based ch.moth.rapy. METh.DSIndividual patient data were pooled from th.ee randomised ph.se III trials of fluoropyrimidine-based ch.moth.rapy ± platinum/anth.acycline in patients with.advanced, untreated gastroesoph.geal adenocarcinoma or squamous cell carcinoma (SCC) randomised between 1994 and 2005. Th. primary endpoint was overall survival of oesoph.geal cancer patients according to h.stology. Secondary endpoints were response rates and a toxicity composite endpoint. RESULTSOf th. total 1836 randomised patients, 973 patients (53%) were eligible (707 patients with.gastric cancer were excluded), 841 (86%) h.d adenocarcinoma and 132 (14%) h.d SCC. Th.re was no significant difference in survival between patients with.adenocarcinoma and SCC, with.median overall survivals of 9.5 mo vs 7.6 mo (h. = 0.85, 95%CI: 0.70-1.03, P = 0.09) and one-year survivals of 38.8% vs 28.2% respectively. Th. overall response rate to ch.moth.rapy was 44% for adenocarcinoma vs 33% for SCC (P = 0.01). Th.re was no difference in th. frequency of th. toxicity composite endpoint between th. two groups. CONCLUSIONTh.re was no significant difference in survival between adenocarcinoma and SCC in patients with.advanced oesoph.geal cancer treated with.fluoropyrimidine-based ch.moth.rapy despite a trend for worse survival and less ch.mo-sensitivity in SCC. Tolerance to treatment was similar in both.groups. Th.s analysis h.gh.igh.s th. unmet need for SCC-specific studies in advanced oesoph.geal cancer and will aid in th. design of future trials of targeted agents.

关键词： Oesoph.geal cancer Adenocarcinoma Ch.moth.rapy Squamous Pooled analysis