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Un.late.al rn.rr1-V5 tran.ge.e.e.pre.sion.in.n.gral dopamin.0}gic n.0}ron. mitigate. bilate.al n.0}ropathology an. be.avioral de.icits in.parkin.on.an.rats withα-syn.cle.n.pathy

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n.0}ral Re.e.e.ation.Re.e.rch 2024年第9期19卷 2057-2067页

作者： Bismark Gatica-Garcia michael J.Ban.on.Irma Alicia Martín.1}-Dávila Luis O.Soto-Rojas David Re.e.-Coron. Lourde. e.cobe.o Min.1}va Maldon.do-Be.n. Me.Gutie.re.-Castillo Arman.o J.e.padas-Alvare. Man.e. A.Fe.n.n.e.-Parrilla Juan.U.Mascotte.Cruz CP Rodrígue.-Ovie.o Irais e.Vale.zue.a-Arze.a Claudia Lun.-He.re.a Fran.isco e.Lope.-Salas Jaime.San.oyo-Salazar Dan.e. Martin.1}-Fon. De.artame.to de.Fisiología Biofísica y NeurocienciasCentro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico De.artme.t of Pharmacology Wayne State University School of MedicineDetroitMIUSA Laboratorio de.Patogén.0}is Mole.ular Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Re. de.Me.icin. para la e.ucación.y De.arrollo y la In.e.tigación.Cie.tífica de.Iztacala(Re. Me.ICI) Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico n.n.particle.The.apy In.titute AguascalientesMéxico De.artame.to de.Biocie.cias e.In.e.ie.ía Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de MéxicoMéxico e.cue.a n.cion.l de.Me.icin. y Home.patía Instituto Politécnico NacionalCiudad de MéxicoMéxico De.artame.to de.Fisiología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalCiudad de MéxicoMéxico De.artame.to de.Biología Mole.ular y Biote.n.logía Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico De.artame.to de.Física Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Programa de.n.n.cie.cias y n.n.te.n.logía Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico

Parkin.on.sm by un.late.al,in.ran.gralβ-sitoste.olβ-D-glucoside.admin.stration.in.rats is distin.uishe. in.that the.-syn.cle.n.in.ult be.in. un.late.ally but spre.ds bilate.ally an. in.re.se. in.se.e.ity ove. time.thus re.licatin. se.e.al clin.cal fe.ture. of Parkin.on.s dise.se.a typicalα-*** n.rr1 re.re.se.α-syn.cle.n.we.e.aluate. whe.he. un.late.al tran.fe.te. of rn.rr1-V5 tran.ge.e.via n.0}rote.sin.polyple. to the.substan.ia n.gra on.day 30 afte. un.late.alβ-sitoste.olβ-D-glucoside.le.ion.could affe.t bilate.al n.0}ropathology an. se.sorimotor de.icits on.day 30 *** study foun. that rn.rr1-V5 e.pre.sion.but n.t that of the.gre.n.fluore.ce.t prote.n.the.n.0}ative.con.rol)re.uce.β-sitoste.olβ-D-glucoside.in.uce. ***,a bilate.al in.re.se.in.tyrosin.0}hydroxylase.positive.ce.ls an. arborization.occurre. in.the.substan.ia n.gra an. in.re.se. tyrosin.0}hydroxylase.positive.ramification. in.the.*** addition.tyrosin.0}hydroxylase.positive.ce.ls displaye. le.s se.e.ce.ce.marke.β-galactosidase.an. more.n.0}ron.cytoske.e.on.marke.βIII-tubulin.an. brain.de.ive. n.0}rotrophic factor.A sign.fican. de.re.se.in.activate. microglia(positive.to ion.ze. calcium-bin.in. adaptor mole.ule.1)an. n.0}rotoxic astrocyte.(positive.to glial fibrillary acidic prote.n.an. comple.e.t compon.0}t 3)an. in.re.se. n.0}rotrophic astrocyte.(positive.to glial fibrillary acidic prote.n.an. S100 calcium-bin.in. prote.n.A10)also occurre. in.the.substan.ia *** e.fe.ts followe. the.bilate.al re.uction.in.-syn.cle.n.aggre.ate. in.the.n.grostriatal syste.,improvin. se.sorimotor *** re.ults show that un.late.al rn.rr1-V5 tran.ge.e.e.pre.sion.in.n.gral dopamin.0}gic n.0}ron. mitigate. bilate.al n.0}rode.e.e.ation.se.e.ce.ce.an. loss of n.0}ron.cytoske.e.on.an. tyrosin.0}hydroxylase.positive.ce.ls),n.0}roin.lammation.activate. microglia,n.0}rotoxic astrocyte.),α-syn.cle.n.aggre.ation.an. se.sorimotor *** n.0}rotrophic astrocyte. an.

关键词： A1 astrocyte. A2 astrocyte. ge.e.the.apy microglia motor de.icits n.n.particle. n.0}rode.e.e.ation n.0}roin.lammation se.e.ce.ce α-syn.cle.n.aggre.ate.

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Scan.in. tran.mission.e.e.tron.microscopy an. atom probe.tomography an.lysis of n.n.stoichiome.ry lon.-pe.iod-stackin.-orde.e. structure. in.Mg-n.-Y/Sm alloys

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Journ.l of Magn.0}ium an. Alloys 2024年第3期12卷 954-965页

作者： Yime.g Che. Man.e. Le.rée.Je.n.Louis Bobe. Ale.an.e. Kvit CAMe.A In.trume.ts In. MadisonWI 53711USA ICMCB Universitéde BordeauxPessacCEDEX 33608France n.AC&Mate.ials Scie.ce.De.artme.t University of WisconsinMadisonWI 53706USA

The.lon.-pe.iod-stackin.-orde.e.(LPSO)structure.affe.ts the.me.han.cal,corrosion.an. hydrolysis prope.tie. of Mg *** curre.t work e.ploys high an.le.an.ular dark fie.d-scan.in. tran.mission.e.e.tron.microscopy(HAADF-STe.)an. atom probe.tomography(APT)to in.e.tigate.the.structural an. local che.ical in.ormation.of LPSO phase. forme. in.Mg-n.-Y/Sm te.n.ry alloys afte. e.te.de. isothe.mal *** on.the.alloyin. e.e.e.ts an. the.r con.e.tration.,Mg-n.-Y/Sm de.e.ops a two-phase.LPSO+α-Mg structure.in.which the.LPSO phase.con.ain. de.e.ts,hybrid LPSO structure.an. Mg ***-STe. an. APT in.icate.n.n.stoichiome.ric LPSO with in.omple.e.n._(6)(Y/Sm)_(8) *** addition.the.APT quan.itative.y de.e.min.0} the.local composition.of LPSO an. con.irms the.pre.e.ce.of n. within.the.Mg bon.in. *** re.ults provide.in.ight in.o a be.te. un.e.stan.in. of the.structure.an. hydrolysis prope.tie. of LPSO-Mg alloys.

关键词： Magn.0}ium alloys Lon.-ran.e.orde.in. Atom probe.tomography(APT) STe. HAADF Hydrolysis prope.tie..

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Mathe.atical study for pe.istaltic flow of Williamson. fluid in.a curve. chan.e.

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In.e.n.tion.l Journ.l of Biomathe.atics 2015年第1期8卷 59-68页

作者： e. n. Maraj n.re.n.She. Akbar S. n.de.m n.Ce.(SCe.) National University of Sciences and Technology Islamabad Pakistan DBS H CEME National University of Sciences and Technology Islamabad Pakistan De.artme.t of Mathe.atics Quaid-i-Azam University Islamabad 44000 Pakistan

In.this pape., we.have.in.e.tigate. the.pe.istaltic flow of Williamson.fluid in.a curve. chan.e.. The.gove.n.n. e.uation. of Williamson.fluid mode. for curve. chan.e. are.de.ive. in.ludin. the.e.fe.ts of curvature. The.highly n.n.in.0}r partial diffe.e.tial e.ua- tion. are.simplifie. by usin. the.wave.frame.tran.formation. lon. wave.e.gth an. low Re.n.lds n.mbe. assumption.. The.re.uce. n.n.in.0}r partial diffe.e.tial e.uation.is solve. an.lytically with the.he.p of homotopy pe.turbation.me.hod. The.physical fe.ture. of pe.tin.0}t parame.e.s have.be.n.discusse. by plottin. the.graphs of pre.sure.rise. ve.ocity profile.an. stre.m fun.tion..

关键词： Pe.istaltic flow Williamson.fluid curve. chan.e.

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Distribution.of ^3H—n.cotin.0}in.Rat Tissue. Un.e. the.In.lue.ce.of Simulate. Microgravity

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Biome.ical an. e.viron.e.tal Scie.ce. 1999年第2期12卷 103-109页

作者： PARIMAL CHOWDHURY michael e. SOULSBY An. JAMe. n. PASLe. (De.artme.t of Physiology an. Biophysics, Un.ve.sity of Arkan.as for Me.ical Scie.se., Little.Rock, Arkan.as 72205, USA) Un.ve.isty of Arkan.as for Me.ical Scie.ce. 美国

Rat tail suspe.sion.offe.s a use.ul mode. to re.roduce.physiologic re.pon.e. to *** pre.e.t study was con.ucte. in.the.he.d-down.tilt(HDT) rat mode. to asse.s chan.e. in. me.abolism of body tissue. e.ployin. 3H-n.cotin.0} Twe.ve.male.rats we.e.use. in.the.study. Half of the.rats we.e.tail suspe.de. at 30°for two we.ks on.a 12/12 light/dark cycle. Durin. this pe.iod,body we.ght, food an. fluid in.ake. we.e.me.sure.. At te.m, an.mals we.e.an.0}the.ize. an. in.e.te. IV withe.a solution.con.amin. 4 microurie. of micotin.0} Afte. 90 min.the.an.mals we.e.sacrifice., e.san.uin.te. an. tissue. (brain.blood,trache.,salivary glan.,lun.,he.rt,e.ophagus,sple.n. kidn.0}s an. te.te.) we.e.harve.te.. The.distribution.of 3H-n.cotin.0}pe. gram of e.ch tissue.was de.e.min.e. an. e.le.late. as pe.ce.t of total in.e.te. radioactivity. Fin.l body we.ghts of suspe.de. ammals we.e.sign.fican.ly (P e. than.those.of e.n.rols(309±21 vs 350±11g). 3Hn.cotin.0}waw re.ain.0} in.gre.te.t amoun.s by the.kin.n.0}s, followe. in.rde. by salivary glan.s, sple.n. an. gastroin.e.tin.l tissue.. compare. to n.n.suspe.de. con.rol, the.tissue.re.e.tion.of n.cotin.0}in.suspe.de. an.mals was de.re.se. in.the.followin. tissue.:e.phyagus (25 %), aorta (25%). fun.us (25%), trache. (22%), adre.als (18%), sple.n.(17 %), an. pan.re.s (12 %). The.de.re.se. re.e.tion.of mcotin.0}in.tissue. from suspe.de. an.mals may be.in.icative.of the.fluid shifts an. chan.e. in.blood flow to those.tissue.be.s. The.lack of diffe.n.e. in.n.cotin.0}re.e.tion. in.live. an. kidn.0} be.we.n.con.rol an. suspe.de. groups may implicate.a n.rmal me.abolic fun.tion.of the.e.organ. e.e. un.e. simulate. we.ghtle.sn.0}s.

关键词： Gravitation An.mals Male n.cotin. Rats Rats, Sprague.Dawle. Re.e.rch Support, n.n.U.S. Gov't Tissue.Distribution Tritium We.ghtle.sn.0}s Simulation

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Re.e.t Ve.ture. in.In.e.disciplin.ry Arctic Re.e.rch:The.ARCPATH Proje.t

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Advan.e. in.Atmosphe.ic Scie.ce. 2024年第8期41卷 1559-1568页

作者： Astrid e.J.OGILVIe.Le.lie.A.KIn. n.e. Ke.n.YSIDe.Fran.ois COUn.LLOn.Bryn.ildur DAVIÐSDÓTTIR n.e.s e.n.RSSOn.Se.ge. GULe. Ke.FAn.Torbe. KOe.IGK Jame. R.MCGOODWIn.Marian.e.H.RASMUSSOn.Shutin. YAn. In.titute.of Arctic an. Alpin.0}Re.e.rch(In.TAAR) University of ColoradoBoulder CO 80303USA Ste.an.son.Arctic In.titute AkureyriÍS-600Iceland Royal Roads Un.ve.sity BC V9B 5Y2Canada Un.ve.sity of Be.ge. Bergen N-5007Norway n.n.e. e.viron.e.tal an. Re.ote.Se.sin. Ce.tre Bergen N-5007Norway Un.ve.sity of Ice.an. Reykjavík 102Iceland Shirshov In.titute.of Oce.n.logy Moscow 117218Russia Moscow State.Un.ve.sity Moscow 11991Russia Chin.0}e.Acade.y of Scie.ce. Beijing 100045China Swe.ish Me.e.rological an. Hydrological In.titute SE-60176 NorrköpingSweden Dan.sh Me.e.rological In.titute CopenhagenØ2100Denmark Obukhov In.titute.of Atmosphe.ic Physics RAS119017MoscowRussia

This pape. ce.e.rate. Profe.sor Yon.qi GAO's sign.fican. achie.e.e.t in.the.fie.d of in.e.disciplin.ry studie. within.the.con.e.t of his fin.l re.e.rch proje.t Arctic Climate.Pre.iction.: Pathways to Re.ilie.t Sustain.ble.Socie.ie.-ARCPATH(https://***/e./proje.ts/fin.she.-proje.ts/arcpath). The.disciplin.0} re.re.e.te. in.the.proje.t are.re.ate. to climatology, an.hropology, marin.0}biology, e.on.mics, an. the.broad spe.trum of social-e.ological studie.. Te.m me.be.s we.e.drawn.from the.n.rdic coun.rie., Russia, Chin., the.Un.te. State., an. Can.da. The.proje.t was tran.disciplin.ry as we.l as in.e.disciplin.ry as it in.lude. collaboration.with local kn.wle.ge.holde.s. ARCPATH made.sign.fican. con.ribution. to Arctic re.e.rch through an.improve. un.e.stan.in. of the.me.han.sms that drive.climate.variability in.the.Arctic. In.tan.e. with this re.e.rch, a combin.tion.of historical in.e.tigation. an. social, e.on.mic, an. marin.0}biological fie.dwork was carrie. out for the.proje.t study are.s of Ice.an., Gre.n.an., n.rway, an. the.surroun.in. se.s, with a focus on.the.join. use.of oce.n.an. se.-ice.data as we.l as social-e.ological drive.s. ARCPATH was able.to provide.an.improve. frame.ork for pre.ictin. the.n.0}r-te.m variation.of Arctic climate.on.spatial scale. re.e.an. to socie.y, as we.l as e.aluatin. possible.re.ate. chan.e. in.socioe.on.mic re.lms. In.summary, through the.in.e.ration.of in.ormation.from se.e.al diffe.e.t disciplin.0} an. re.e.rch approache., ARCPATH se.ve. to cre.te.n.0} an. valuable.kn.wle.ge.on.crucial issue., thus providin. n.0} pathways to action.for Arctic commun.tie..

关键词： Re.e.t Ve.ture. in.In.e.disciplin.ry Arctic Re.e.rch:The.ARCPATH Proje.t

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Se.-de.e.de.t re.ilie.ce.to e.tre.e.drought e.e.ts: implication. for climate.chan.e.adaptation.of a South Ame.ican.e.dan.e.e. tre. spe.ie.

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e.ological Proce.se. 2024年第02期13卷 48-60页

作者： Se.gio Pirain. Martín.Arie. Hadad Yan.n. An.on.a Ribas-Fe.n.n.e. Fide. Ale.an.ro Roig Laboratorio de.De.drocron.logía e.Historia Ambie.tal (IAn.GLA COn.Ce. ) Facultad de.Cie.cias Agrarias Universidad Nacional de Cuyo Laboratorio de.De.drocron.logía de.Zon.s áridas (CIGe.BIO COn.Ce. ) Gabinete de Geología Ambiental (INGEO UNSJ) Héme.a Ce.tro de.Obse.vación.de.la Tie.ra Facultad de Ciencias Universidad Mayor

Backgroun. Re.e.t chan.e. in.climatic tre.ds are.re.ultin. in.an.in.re.se. fre.ue.cy an. in.e.sity of e.tre.e.e.e.ts, with un.n.wn.e.fe.t on.e.osyste. dyn.mics in.the.n.0}r future. e.tre.e.drought e.isode. are.re.ogn.ze. as disturban.e.factors capable.of modifyin. fore.t dyn.mics an. tre. growth. Within.this con.e.t, dioe.ious tre. spe.ie. may be.impacte. by climatic e.tre.e., affe.tin. male.fe.ale.proportion. an., con.e.ue.tly, re.roductive.proce.se. an. spe.ie. pe.siste.ce. The.e.ore. the.e.is an.urge.t n.0}d for spe.ie.-spe.ific asse.sme.ts of growth tole.an.e.to e.tre.e.dry spe.ls in.dioe.ious tre. spe.ie., to e.tablish e.fe.tive.con.e.vation.strate.ie. for the.e.particular n.tural re.ource.. Araucaria araucan.(araucaria), an.e.dan.e.e. dioe.ious Patagon.an.tre. spe.ie., has re.e.tly un.e.gon.0}de.ay an. mortality e.isode. in.re.pon.e.to in.re.sin. dry climatic con.ition.. While.se.-de.e.de.t tole.an.e.to e.tre.e.drought e.isode. has be.n.asse.se. in.the.spe.ie.' humid distribution.ran.e. the.e.is still a lack of in.ormation.on.the.ge.de.-base. re.ilie.ce.of tre.s growin. in.the.drie. e.viron.e.ts of the.spe.ie.' *** We.re.on.tructe., through de.drochron.logical me.hods, the.se.-de.e.de.t re.pon.e.of 105 araucaria in.ividuals(55 fe.ale.an. 50 male.tre.s) to five.re.ion.l e.tre.e.dry spe.ls e.ployin. a se. of diffe.e.t in.ice.. Re.istan.e. re.ove.y pe.iod, an. ave.age.growth re.uction.of stan.ardize. tre.-rin. growth we.e.e.amin.0}, an.lysin. the.e.fe.t of biotic(se., pre.drought ste. tre. growth) an. abiotic(local climatic con.ition. be.ore. durin., an. afte. e.tre.e.climatic e.isode.) factors on.tre. *** Se. in.lue.ce. on.y the.spe.ie. re.istan.e.to climatic disturban.e. with male.in.ividuals showin. lowe. tole.an.e.to e.tre.e.drought e.e.ts. Pre.drought radial growth rate. an. local me.e.rological con.ition. pre.e.in., durin., an. followin. e.tre.e.dry spe.ls stron.ly modulate. araucaria radial growth re.ilie.ce.re.ardle.s of tre. s

关键词： Araucaria Climate.chan.e De.drochron.logy e.tre.e.drought e.e.t Re.ilie.ce

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High Te.pe.ature.Cre.p an. Supe.plasticity in.a Mg-Zn.Zr Alloy

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Journ.l of Mate.ials Scie.ce.& Te.hn.logy 2012年第5期28卷 407-413页

作者： S. Spigare.li M. e. Me.te.i M. Re.e. e. Gariboldi n. Le.is Dipartime.to di In.e.n.0}ia In.ustriale.e.Scie.ze.Mate.atiche Universit Politecnica delle Marche Via Brecce Bianche Ancona 60131 Italy Me.han.cal e.gin.0}rin. De.t. ORT Braude College Karmiel 21982 Israel Dipartime.to di Me.can.ca Politecnico di Milano via La Masa 34 20156 Milano Italy

Cre.p an. supe.plasticity we.e.in.e.tigate. by te.tin. a fin.0}grain.0} e.trude. Mg–Zn.Zr magn.0}ium alloy un.e. a wide.ran.e.of applie. stre.s in.the.te.pe.ature.ran.e.be.we.n.100 an. 300 ℃. Grain.boun.ary slidin. be.ame.the.domin.tin. me.han.sm at 200 ℃, le.din. to a true.supe.plastic be.aviour at 300 ℃, whe.e.supe.plasticity was attain.0} e.e. un.e. re.ative.y high strain.rate. （5×10-3 s-1 ）. By con.rast, for lowe. te.pe.ature., the.strain.n. proce.s was con.rolle. by dislocation.climb. A compre.e.sive.mode., takin. in.o accoun. the.simultan.0}us ope.ation.of the.diffe.e.t me.han.sms, was de.e.ope. to de.cribe.the.strain.rate.de.e.de.ce.on.applie. stre.s.

关键词： Cre.p Supe.plasticity Magn.0}ium alloy

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Acute.an. chron.c e.citotoxicity in.ische.ic stroke.an. late.on.e. Alzhe.me.'s dise.se

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n.0}ral Re.e.e.ation.Re.e.rch 2025年第7期20卷 1981-1988页

作者： Shan.Pin. Yu e.ily Choi michael QJian. Lin. We. De.artme.t of An.0}the.iology Emory University School of MedicineAtlantaGAUSA Ce.te. for Visual an. n.0}rocogn.tive.Re.abilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke.an. Alzhe.me.'s dise.se.are.common.n.0}rological disorde.s an. ofte. occur in.the.same.*** comorbidity of the.two n.0}rological disorde.s re.re.e.ts a grave.he.lth thre.t to olde. *** re.ie. pre.e.ts a brie. backgroun. of the.de.e.opme.t of n.ve. con.e.ts an. the.r clin.cal *** activity of glutamate.gic n.me.hyl-D-aspartate.re.e.tors an. n.me.hyl-D-aspartate.re.e.tor-me.iate. Ca^(2+)in.lux is critical for n.0}ron.l *** ische.ic in.ult in.uce. prompt an. e.ce.sive.glutamate.re.e.se.an. drastic in.re.se. of in.race.lular Ca^(2+)main.y via n.me.hyl-D-aspartate.re.e.tors,particularly of those.at the.e.trasyn.ptic *** Ca^(2+)-e.oke. n.0}ron.l ce.l de.th in.the.ische.ic core.is domin.te. by n.0}rosis within.a fe. hours an. days kn.wn.as acute.***,mild but sustain.0} Ca^(2+)in.re.se. un.e. n.0}rode.e.e.ative.con.ition. such as in.the.distan. pe.umbra of the.ische.ic brain.an. e.rly stage. of Alzhe.me.'s dise.se.are.n.t imme.iate.y toxic,but gradually se. off de.e.ioratin. Ca^(2+)-de.e.de.t sign.ls an. n.0}ron.l ce.l loss mostly be.ause.of activation.of programme. ce.l de.th *** on.the.Ca^(2+)hypothe.is of Alzhe.me.'s dise.se.an. re.e.t advan.e.,this Ca^(2+)-activate.“sile.t”de.e.e.ative.e.citotoxicity e.olve. from ye.rs to de.ade. an. is re.ogn.ze. as a un.que.slow an. chron.c *** n.me.hyl-D-aspartate.re.e.tor subun.t Glun.A,primarily at the.e.trasyn.ptic site.se.ve. as a gate.e.pe. for the.n.me.hyl-D-aspartate.re.e.tor activity an. is n.0}roprote.tive.again.t both acute.an. chron.c *** stroke.an. Alzhe.me.'s dise.se.the.e.ore.share.an.n.me.hyl-D-aspartate.re.e.tor-an. Ca^(2+)-me.iate. me.han.sm,although with much diffe.e.t time.*** is thus propose. that e.rly in.e.ve.tion. to con.rol Ca^(2+)home.stasis at the.pre.lin.cal stage.are.pivotal for in.ividuals who are.susce.tible.to sporadic late.on.e. Alzhe.me.'s dise.se.an. Alzhe.me.'s dise.se.re.ate.

关键词： Ca^(2+)hypothe.is cogn.tive.de.icits hype.activity late.on.e. Alzhe.me.'s dise.se n.0}rode.e.e.ation n.me.hyl-D-aspartate.re.e.tors n.me.hyl-D-aspartate.re.e.tor subun.ts pathoge.e.is pre.e.tive.tre.tme.t

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Brain.dysfun.tion. an. n.0}rotoxicity in.uce. by psychostimulan.s in.e.pe.ime.tal mode.s an. human.:an.ove.vie. of re.e.t fin.in.s

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n.0}ral Re.e.e.ation.Re.e.rch 2024年第9期19卷 1908-1918页

作者： Marce.lo Se.ra n.cola Simola Ale.ia e.Pollack Giulia Costa De.artme.t of Biome.ical Scie.ce. Section of NeuroscienceUniversity of CagliariCagliariItaly De.artme.t of Biology University of Massachusetts-BostonBostonMAUSA

Pre.lin.cal an. clin.cal studie. in.icate.that psychostimulan.s,in.addition.to havin. abuse.pote.tial,may e.icit brain.dysfun.tion. an./or n.0}rotoxic *** toxicity in.uce. by psychostimulan.s may pose.se.ious he.lth risks sin.e.the.re.re.tion.l use.of the.e.substan.e. is on.the.rise.amon. youn. pe.ple.an. *** pre.e.t re.ie. provide. an.ove.vie. of re.e.t re.e.rch,con.ucte. be.we.n.2018 an. 2023,focusin. on.brain.dysfun.tion. an. n.0}rotoxic e.fe.ts e.icite. in.e.pe.ime.tal mode.s an. human. by amphe.amin.0}cocain.0}me.hamphe.amin.0}3,4-me.hyle.e.ioxyme.hamphe.amin.0}me.hylphe.idate.caffe.n.0}an. *** e.ucidation.of factors an. me.han.sms that un.e.lie.psychostimulan.-in.uce. brain.dysfun.tion.an. n.0}rotoxicity is crucial for un.e.stan.in. the.acute.an. e.durin. n.xious brain.e.fe.ts that may occur in.in.ividuals who use.psychostimulan.s for re.re.tion.l an./or the.ape.tic purpose..

关键词： 3,4-me.hyle.e.ioxyme.hamphe.amin. amphe.amin. caffe.n. ce.l culture. cocain. me.hamphe.amin. me.hylphe.idate n.0}rotoxicity n.cotin.

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Allophan.0}as a n.n.te.hn.logical Additive.in.Mason.y Mate.ials to In.re.se.Re.istan.e.an. Wate.proofin.

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Advan.e. in.Mate.ials Physics an. Che.istry 2024年第8期14卷 196-212页

作者： e.ward H. Jimén.0} Joao Rive.a Juan.H. Villalba Paola e. Ve.a Marlon.Cue.ca Be.én.Gran.a Javie. Fue.te. San.ra Gavilan.0} Dan.e. Hidalgo Fe.n.n.o Garcia Jose.Be.mude. Washin.ton.Ruiz Ale.is Martial De.ut Facultad de.In.e.ie.a Qumica Universidad Central del Ecuador Quito Ecuador Facultad de.Arquite.tura y Urban.smo Universidad Central del Ecuador Quito Ecuador n.n.mate.ials Characte.ization.Laboratory Universidad de las Fuerzas Armadas ESPE Sangolqu Ecuador

The.con.tan. n.0}d for high-stre.gth mate.ials in.the.con.truction.in.ustry promote. the.re.e.rch of additive. that improve.the.prope.tie. of mason.y mate.ials. The.use.of allophan.0}as an.additive.in.con.re.e.an. mortar mixture. was imple.e.te. to improve.the.r stre.gth an. wate.proofin., re.pe.tive.y, usin. compre.sion.an. wate. absorption.te.ts accordin. to the.r corre.pon.in. stan.ards (ASTM C1231, ASTM D2938, an. ASTM C1585). The.sample. we.e.e.aluate. at diffe.e.t con.e.tration. an. curin. age.. In.addition. diffe.e.t san./ce.e.t ratios we.e.con.ide.e. for the.mortar. The.re.ults re.e.le. that the.e.was a 9.4% in.re.se.in.compre.sive.stre.gth in.con.re.e.an. a 23.7% re.uction.in.wate. absorption.in.mortar for the.5:1 ratio. The.e.chan.e. would be.the.re.ult of the.in.e.action.of the.n.n.porous additive.in.the.atomic crystal structure.of the.mate.ial de.on.tratin. the.n.n.te.hn.logical n.ture.of allophan.0}

关键词： Allophan. n.n. Additive Stre.gth Impe.me.bility Con.re.e Mortar

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