检索结果-南通市图书馆

JUPITER-02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Communications 2022年第1期42卷 56-59页

作者： Laura Ling Ying Tan Quynh-Thu le Nancy Ying Ying lee Melvin lee Kiang Chua Ministry of Health Holdings Singapore 099253Singapore Department of Radiation Oncology Stanford UniversityCalifornia 94305USA Department of Radiation Oncology Memorial Sloan Kettering Cancer CenterNew York 10065USA Department of Head and Neck and Thoracic Cancers Division of Radiation Oncology and Division of Medical SciencesNational Cancer Centre SingaporeSingapore 169610Singapore Oncology Academic Clinical Programme Duke-NUS Medical SchoolSingapore 169857Singapore

Nasopharyngeal carcinoma(NPC)is a disease with unique *** is endemic in Southern China,Southeast Asia,and North Africa,and typically affects males more than females in the 30-60 years age group[1].Globally,133,354 NPC cases were diagnosed in 2020 with 80,008;deaths in the same year[2].While the survival rates of early-stage NPC after radiotherapy(RT)are high,dis-ease recurrences are common in locoregionally-advanced NPC,with the predominant pattern of failure being dis-tant metastasis[3].In this clinical scenario,palliative chemotherapy is the primary treatment modality。

关键词： epidemiology chemotherapy nasopharyngeal

A self-stabilised walking gait for humanoid robots based on the essential model with internal states

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

IET Cyber-Systems and Robotics 2022年第4期4卷 283-297页

作者： Qiuyue Luo Christine Chevallereau Yongsheng Ou Jianxin Pang Victor De-león-Gómez Yannick Aoustin Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhenChina Research Institute of UBTech Robotics ShenzhenChina Laboratoire des Sciences du Numerique de Nantes(LS2N) CNRSCentrale NantesNantes UniversitéNantesFrance FCA at the Univerdidad Autónoma de Coahuila TorreónMéxico

Walking stability is one of the key issues for humanoid robots.A self-stabilised walking gait for a full dynamic model of humanoid robots is *** simplified models,that is,the linear inverted pendulum model and variable-length inverted pendulum model,self-stabilisation of walking gait can be obtained if virtual constraints are properly *** result is extended to the full dynamic model of humanoid robots by using an essential dynamic model,which is developed based on the zero dynamics *** the proposed method,a robust stable walking for a humanoid robot is achieved by adjusting the step timing and landing position of the swing foot automatically,following its intrinsic dynamic *** exempts the robot from the time-consuming high-level control approaches,especially when a full dynamic model is *** different walking patterns/features(i.e.,the swing foot motion,the vertical centre of mass motion,the switching manifold configuration,etc.)affect the stability of the walking gait is *** are conducted on robots Romeo and TALOS to support the results.

关键词： dynamic stability humanoid and bipedal locomotion passive walking

基于ADAMS的全断面竖井掘进机锥形刀盘载荷特性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

科学技术与工程 2024年第17期24卷 7122-7130页

作者：王帅郭庚鑫李阁强董振乐李东林韩伟锋焦雷宋斌河南科技大学机电工程学院洛阳471003 机械装备先进制造河南省协同中心洛阳471003 盾构及掘进技术国家重点实验室郑州450001 中铁十五局集团有限公司上海200000 营口市环境工程开发有限公司营口115000

全断面竖井掘进机锥形刀盘在竖井施工中具有导向性好、姿态调整方便等优点,滚刀作为竖井掘进机施工中最直接的破岩工具,获取其载荷分布规律对于竖井掘进机的刀盘刀具系统的合理设计和掘进过程中装备姿态的调整具有重要意义。基于ADAMS... 详细信息

全断面竖井掘进机锥形刀盘在竖井施工中具有导向性好、姿态调整方便等优点,滚刀作为竖井掘进机施工中最直接的破岩工具,获取其载荷分布规律对于竖井掘进机的刀盘刀具系统的合理设计和掘进过程中装备姿态的调整具有重要意义。基于ADAMS建立了全断面竖井掘进机锥形刀盘与岩体耦合模型,合理施加约束条件对正常掘进工况进行仿真,获取了竖井掘进机锥形刀盘刀具的载荷分布规律。结果表明:由于安装方式的不同,正滚刀所受到的侧向力和滚动力均大于中心滚刀,对正滚刀刀座与辐条之间的连接强度提出了更高要求;随着正滚刀在刀盘上安装半径的增大,其受到的垂直力也增大。中心滚刀所受到合力载荷稳定性较正滚刀明显较好,波动更小;随着滚刀在刀盘上安装半径的增加,滚刀所受到的合力载荷大小波动更大,载荷稳定性也更差。

关键词：全断面竖井掘进机 ADAMS动力学仿真锥形刀盘滚刀载荷雨流计数稳定性分析

对心脏停搏复苏病人大剂量肾上腺素治疗的可能并发症

在线全文

学校读者我要写书评

暂无评论

美国医学会杂志（中文版） 1991年第4期10卷 206-212页

作者： mich.,C Chri.,WB

Primary intramedullary melanoma of lumbar spinal cord: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第10期9卷 2352-2356页

作者： le-Dong Sun Xin Chu Li Xu Xiu-Zhen Fan Yi Qian Da-Ming Zuo Department of Dermatology The Fifth Affiliated HospitalSouthern Medical UniversityGuangzhou 510900Guangdong ProvinceChina The Fifth Affiliated Hospital Southern Medical UniversityGuangzhou 510900Guangdong ProvinceChina Department of Medical Laboratory Southern Medical UniversityGuangzhou 510515Guangdong ProvinceChina

BACKGROUND Primary intramedullary melanoma is a very rare tumor,most frequently occurring in the cervical and thoracic spinal *** SUMMARY We present a rare case in which the primary intramedullary melanoma was located in the lumbar spine.A 56-year-old man complained of progressive intermittent pain in the lumbar *** magnetic resonance imaging showed a spinal intramedullary tumor between the L3 and S1 *** tumor was resected entirely,and the diagnosis of malignant melanoma was confirmed by *** Primary melanoma of the spinal cord,particularly intramedullary localization,has rarely been reported in the previous *** describe a primary malignant melanoma of the lumbar spinal cord and discuss the challenges associated with the diagnosis.

关键词： Intramedullary melanoma Spinal cord Lumbar Magnetic resonance imaging Histopathological examination Immunohistochemical staining Case report

Radical surgery for Budd-Chiari syndrome through exposure of the entire inferior vena cava of the hepatic segment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2007年第8期120卷 626-629页

作者： ZHANG Xiao-ming LI Qing-le Department of Vascular Surgery Peking University People＇s Hospital Beijing 100044 China

Background Several kinds of radical surgery for the treatment of Budd-Chiari syndrome （BCS） have been devised. We have described preliminary efforts to treat BCS using a novel radical resection technique to expose the entire inferior vena cava （IVC） of the hepatic segment. Methods Sixty patients with BCS were treated by radical resection, including 46 men and 14 women. BCS patients ranged in age from 11 to 62 years, with 3 months to 11 years since the BCS diagnosis. The lesions included membrane occlusion of the IVC in 16 patients, double membranes within the IVC in 2 patients, double membranes within the IVC and the hepatic vein （HV） in 3 patients, IVC membrane with distal thrombosis in 10 patients, long segment thrombosis of the IVC in 5 patients （organized thrombosis in 2 patients, fresh thrombosis in 3 patients）, occlusion of the outlet of the HVs due to mural thrombosis in 2 patients, segmental occlusion of the IVC in 3 patients, membranes within the HV with IVC stenosis due to protrusion of HV stent in 1 patient, HV membranes in 11 patients, extensive occlusion of HVs in 1 patient, the whole IVC tumor thrombus with tumor thrombus of 2/3 right atrium resulting from a posterior peritoneum tumor in 1 patient, IVC leiomyosarcoma in 2 patients, IVC leiomyosarcoma with tumor thrombus into 1/2 right atrium in 1 patient, IVC thrombosis extending into right atrium in 1 patient, compression of supra-hepatic segment of IVC due to fiber trabs in 1 patient. Results All lesions were successfully resected under direct supervision. Three procedures were performed under extracorporeal circulation, 52 patients with catheterization of the right atrium, 4 patients with a cell saver, and one patient with auto-retrieval of blood. The retrieved blood was from 300 ml to 4000 ml. Transfusion of banked blood was from 400 ml to 2000 ml for 14 patients. For the other patients no transfusion of banked blood was required. One patient died of renal failure peri-operatively. Newly formed

关键词： hepatic vein thrombosis inferior vena cava

Expression of an Antisense BcMF3 Affects Microsporogenesis and Pollen Tube Growth in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2006年第5期5卷 339-345页

作者： LIU le-cheng CAO Jia-shu YU Xiao-lin XIANG Xun FEI Yong-jun Institute of Vegetable Science Zhejiang University Hangzhou 310029 P.R. China College of Horticulture and Gardening Yangtse University Jingzhou 434025 P.R. China

In an effort to provide some information relevant to the molecular mechanism of genic male sterility in plants, BcMF3 gene that encodes a pectin methylesterase was isolated from the fertile B line of Chinese cabbage-pak-choi （Brassica rapa ssp. chinensis, syn. B. campestris ssp. chinensis）. In the present paper, a 455-bp antisense cDNA fragment of BcMF3 was introduced to binary vector pB1121, and then was mobilized into Agrobacterium tumefaciens strain LBA4404. The A. tumefaciens harboring the BcMF3 antisense fragment was transformed to Arabidopsis thaliana by floral dip. Scanning electronic microscopy examination demonstrated that 47.8% of BcMF3 antisense pollen grains exhibited abnormal shape, which might lead to decreased germination of pollens, suggesting that the product of BcMF3 gene plays an important role during microsporogenesis. The evidence on burst of 45.7% of BcMF3 antisense pollen tubes in vitro and a majority of BcMF3 antisense pollens restricted within the stigmatic tissue revealed that BcMF3 is involved in aiding the growth of pollen tubes. The results suggest that BcMF3 acts at both stages of microsporogensis and pollen tube growth.

关键词： antisense BcMF3 microsporogenesis pectin methylesterase (PME) pollen

基于整体-局部方法的焊接构架承载能力的分析

在线全文

学校读者我要写书评

暂无评论

铁道学报 2011年第8期33卷 33-38页

作者：张乐乐李培崔进北京交通大学机械与电子控制工程学院北京100044 中国铁道科学研究院基础设施检测研究所北京10086

高速列车转向架焊接构架是重要的承载部件,承载能力与状况直接关系到安全运营。针对焊接构架承载问题,通过整体模型承载分析确定局部薄弱结构位置、边界条件以及受力信息,实现三重非线性的焊接过程仿真,通过温度场与应力场结果与试验对... 详细信息

高速列车转向架焊接构架是重要的承载部件,承载能力与状况直接关系到安全运营。针对焊接构架承载问题,通过整体模型承载分析确定局部薄弱结构位置、边界条件以及受力信息,实现三重非线性的焊接过程仿真,通过温度场与应力场结果与试验对比验证其可行性。以非闭合焊缝牵引座结构为例,建立局部模型,分析对比焊接残余应力对结构承载的影响。

关键词：承载分析构架焊接仿真残余应力

CiteOpinion: Evidence-based Evaluation Tool for Academic Contributions of Research Papers Based on Citing Sentences

在线全文

学校读者我要写书评

暂无评论

Journal of Data and Information Science 2019年第4期4卷 26-41页

作者： Xiaoqiu le Jingdan Chu Siyi Deng Qihang Jiao Jingjing Pei Liya Zhu Junliang Yao National Science Library Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100190China

Purpose:To uncover the evaluation information on the academic contribution of research papers cited by peers based on the content cited by citing papers,and to provide an evidencebased tool for evaluating the academic value of cited ***/methodology/approach:CiteOpinion uses a deep learning model to automatically extract citing sentences from representative citing papers;it starts with an analysis on the citing sentences,then it identifies major academic contribution points of the cited paper,positive/negative evaluations from citing authors and the changes in the subjects of subsequent citing authors by means of Recognizing Categories of Moves(problems,methods,conclusions,etc.),and sentiment analysis and topic ***:Citing sentences in a citing paper contain substantial evidences useful for academic *** can also be used to objectively and authentically reveal the nature and degree of contribution of the cited paper reflected by citation,beyond simple citation *** implications:The evidence-based evaluation tool CiteOpinion can provide an objective and in-depth academic value evaluation basis for the representative papers of scientific researchers,research teams,and ***/value:No other similar practical tool is found in papers *** limitations:There are difficulties in acquiring full text of citing *** is a need to refine the calculation based on the sentiment scores of citing ***,the tool is only used for academic contribution evaluation,while its value in policy studies,technical application,and promotion of science is not yet tested.

关键词： Cited paper Citing paper Citing sentence Citation motive Citation sentiment Academic contribution Evaluation