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RGA-CNNs: convolutional neural networks based on reduced geometric algebra

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Science China(Information Sciences) 2021年第2期64卷 240-242页

作者： Rui WANG miaomiao shen Xiangyang WANG Wenming CAO School of Communication and Information Engineering Shanghai University College of Information Engineering Shenzhen University

Dear editor,Recently, convolutional neural networks(CNNs) have exhibited high performance particularly in object detection[1], face recognition [2], and image classification [3]. However, there has been little work on CNN models for multidimensional data, such as the three-dimensional(3 D) data,which are typically presented as color images [4]. Traditional real-valued CNN models [4] have achieved state-of-the-art results for gray-scale images.

关键词： Convolutional Neural Networks (CNNs) Reduced Geometric Algebra (RGA) Multivectors Learning Algorithm Multi-dimensional Data

Multi-task Joint Sparse Representation Classification Based on Fisher Discrimination Dictionary Learning

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Computers, Materials & Continua 2018年第10期57卷 25-48页

作者： Rui Wang miaomiao shen Yanping Li Samuel Gomes School of Communication and Information Engineering Shanghai UniversityNo.99 Shangda RoadShanghai200444China School of Mechatronics MethodsModels and Skills Laboratory(M3M)Universite de Technologie de Belfort-Montbeliard90010 Belfort cedexBelfortFrance

Recently,sparse representation classification(SRC)and fisher discrimination dictionary learning(FDDL)methods have emerged as important methods for vehicle *** this paper,inspired by recent breakthroughs of discrimination dictionary learning approach and multi-task joint covariate selection,we focus on the problem of vehicle classification in real-world applications by formulating it as a multi-task joint sparse representation model based on fisher discrimination dictionary learning to merge the strength of multiple features among multiple *** improve the classification accuracy in complex scenes,we develop a new method,called multi-task joint sparse representation classification based on fisher discrimination dictionary learning,for vehicle *** our proposed method,the acoustic and seismic sensor data sets are captured to measure the same physical event simultaneously by multiple heterogeneous sensors and the multi-dimensional frequency spectrum features of sensors data are extracted using Mel frequency cepstral coefficients(MFCC).Moreover,we extend our model to handle sparse environmental *** experimentally demonstrate the benefits of joint information fusion based on fisher discrimination dictionary learning from different sensors in vehicle classification tasks.

关键词： Multi-sensor fusion fisher discrimination dictionary learning(FDDL) vehicle classification sensor networks sparse representation classification(SRC)

miR-27a和miR-128在种植体周围炎患者龈沟液中的水平及其与骨吸收的关系

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国际检验医学杂志 2024年第5期45卷 513-516,522页

作者：沈苗苗陈玲翟云霞上海长征医院口腔科上海200001 上海中医药大学附属龙华医院病理科上海230032

目的探讨微小RNA(miR)-27a和miR-128在种植体周围炎患者龈沟液中的水平及其与骨吸收的关系。方法将2018年1月至2021年12月于上海长征医院口腔科完成牙种植修复术的患者136例纳入研究,根据种植牙状况分为健康种植体患者66例(健康组)和种... 详细信息

目的探讨微小RNA(miR)-27a和miR-128在种植体周围炎患者龈沟液中的水平及其与骨吸收的关系。方法将2018年1月至2021年12月于上海长征医院口腔科完成牙种植修复术的患者136例纳入研究,根据种植牙状况分为健康种植体患者66例(健康组)和种植体周围炎患者70例(炎症组)。另外,选取同期进行牙龈健康检查的志愿者70例作为对照组。收集所有纳入研究者探诊深度(PD)、龈沟出血指数(SBI)、龈沟液量、肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-6、IL-4水平的数据。采用口腔锥形束CT(CBCT)进行骨吸收测定。采用实时荧光定量聚合酶链反应(qPCR)检测龈沟液中miR-27a和miR-128水平。采用Pearson相关法分析种植体周围炎患者龈沟液中miR-27a和miR-128水平及二者与炎症因子、骨吸收量的相关性。结果与对照组相比,炎症组和健康组龈沟液中PD、SBI、龈沟液量、骨吸收量,TNF-α、IL-6、miR-128水平升高,IL-4、miR-27a水平降低,差异均有统计学意义(P<0.05);与健康组相比,炎症组龈沟液中PD、SBI、龈沟液量、骨吸收量、TNF-α、IL-6、miR-128水平升高,IL-4、miR-27a水平降低,差异均有统计学意义(P<0.05)。相关性分析显示,种植体周围炎患者龈沟液中miR-27a和miR-128水平呈负相关(r=-0.365,P=0.002)。种植体周围炎患者龈沟液中miR-27a水平与PD、SBI、骨吸收量、TNF-α、IL-6水平呈负相关(P<0.05),与IL-4水平呈正相关(P<0.05);miR-128水平与PD、SBI、骨吸收量、TNF-α、IL-6水平呈正相关(P<0.05),与IL-4水平呈负相关(P<0.05)。结论miR-128在种植体周围炎患者龈沟液中呈高水平,miR-27a呈低水平,二者与骨吸收相关。

关键词：种植体周围炎微小RNA-27a 微小RNA-128 骨吸收

New insights on the age of the Mengyejing Formation in the Simao Basin,SE Tethyan domain and its geological implications

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Science China Earth Sciences 2021年第2期64卷 231-252页

作者： Maodu YAN Dawen ZHANG Xiaomin FANG Weilin ZHANG Chunhui SONG Chenglin LIU Jinbo ZAN miaomiao shen Key Laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of SciencesBeijing 100101China College of Tourism and Environmental Resource Zaozhuang UniversityZaozhuang 277160China University of Chinese Academy of Sciences Beijing 100049China School of Earth Sciences Key Laboratory of Western China’s Mineral Resources of Gansu ProvinceLanzhou UniversityLanzhou 730000China MLR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing 100037China

Knowledge on the origin and mechanism of the large potash formation in the southeast Tethyan tectonic domain are still under debate,one of which mainly due to the controversial ages of the potash-bearing *** we present a detailed detrital zircon U-Pb geochronologic-magnetostratigraphic study of the potash-bearing Mengyejing(MYJ)Formation(Fm)from the Simao Basin.948 paleomagnetic cores and 4 detrital zircon U-Pb samples were collected from a 932-m thick Jiangcheng *** demagnetization isolated 857 primary characteristic remnant magnetization(ChRM)directions,indicated by positive reversals and fold tests and petrologic *** normal and seven reversed polarity zones were identified and correlated well with chrons C27r to C34n of the geomagnetic polarity timescale(GPTS2012),yielding the first known age sequence of>112 to~63 Ma for the MYJ *** ages for the potash bearing strata in the Simao commenced~20 Ma earlier than those in the adjacent Khorat basins,opposite to the traditional viewpoint that the former would rather correspond to the middle and lower parts of the *** the paleogeographic reconstruction of likely a pan-Simao-Khorat basin during the Cretaceous,~85 Ma would be another important potential period for future potash exploration in the Simao Basin.

关键词： Simao Basin Magnetostratigraphy Potash-bearing sequence Mengyejing Fm >112–~63 Ma Potash formation

Discovering Cathodic Biocompatibility for Aqueous Zn–MnO_(2) Battery:An Integrating Biomass Carbon Strategy

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Nano-Micro Letters 2024年第6期16卷 111-126页

作者： Wei Lv Zilei shen Xudong Li Jingwen Meng Weijie Yang Fang Ding Xing Ju Feng Ye Yiming Li Xuefeng Lyu miaomiao Wang Yonglan Tian Chao Xu Institute of Energy Power Innovation North China Electric Power UniversityBeijing 102206People’s Republic of China Department of Power Engineering School of EnergyPower and Mechanical EngineeringNorth China Electric Power UniversityBaoding 071003People’s Republic of China Key Laboratory of RNA Biology Institute of BiophysicsChinese Academy of SciencesBeijing 100101People’s Republic of China Collaborative Innovation Center of Integrated Exploitation of Bayan Obo Multi‑Metal Resources Inner Mongolia University of Science and TechnologyBaotou 014010People’s Republic of China

Developing high-performance aqueous Zn-ion batteries from sustainable biomass becomes increasingly vital for large-scale energy storage in the foreseeable ***,γ-MnO_(2) uniformly loaded on N-doped carbon derived from grapefruit peel is successfully fabricated in this work,and particularly the composite cathode with carbon carrier quality percentage of 20 wt%delivers the specific capacity of 391.2 mAh g^(−1)at 0.1 A g^(−1),outstanding cyclic stability of 92.17%after 3000 cycles at 5 A g^(−1),and remarkable energy density of 553.12 Wh kg^(−1) together with superior coulombic efficiency of~100%.Additionally,the cathodic biosafety is further explored specifically through in vitro cell toxicity experiments,which verifies its tremendous potential in the application of clinical ***,Zinc ion energy storage mechanism of the cathode is mainly discussed from the aspects of Jahn–Teller effect and Mn domains distribution combined with theoretical analysis and experimental ***,a novel perspective of the conversion from biomass waste to biocompatible Mn-based cathode is successfully developed.

关键词： Aqueous Zn-ion batteries Biocompatibility Jahn-Teller effect Mn domains γ-MnO_(2)

主题解码场域共情时代感召——解析《花繁叶茂》的守正创新

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电视研究 2021年第2期 88-90页

作者：刘延炀沈苗苗南京大学法学院西北师范大学美术学院

电视剧《花繁叶茂》聚焦时代主题,立足脱贫攻坚的现实典型,表现出强烈的剧情创新性、文艺引领性和时代感召性。本文基于主题解码、场域共情、时代感召的分析路径,系统展现该剧在时代内涵、艺术特点等方面的创新要素,以期为我国主旋律影... 详细信息

电视剧《花繁叶茂》聚焦时代主题,立足脱贫攻坚的现实典型,表现出强烈的剧情创新性、文艺引领性和时代感召性。本文基于主题解码、场域共情、时代感召的分析路径,系统展现该剧在时代内涵、艺术特点等方面的创新要素,以期为我国主旋律影视剧创作提供新的思考,为全面打赢脱贫攻坚战提供理论支持和舆论保障。

关键词：脱贫攻坚主旋律影视剧《花繁叶茂》

SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication

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Signal Transduction and Targeted Therapy 2023年第6期8卷 3055-3069页

作者： Pan Pan Weiwei Ge Zhiwei Lei Wei luo Yuqing Liu Zhanwen Guan Lumiao Chen Zhenyang Yu miaomiao shen Dingwen Hu Qi Xiang Wenbiao Wang Pin Wan Mingfu Tian Yang Yu Zhen Luo Xulin Chen Heng Xiao Qiwei Zhang Xujing Liang Xin Chen Yongkui Li Jianguo Wu The First Affiliated Hospital of Jinan University 510632GuangzhouChina Foshan Institute of Medical Microbiology 528315FoshanChina Guangdong Provincial Key Laboratory of Virology Institute of Medical MicrobiologyJinan University510632GuangzhouChina State Key Laboratory of Virology College of Life SciencesWuhan University430072WuhanChina The First People’s Hospital of Foshan 528315FoshanChina

Viral infection in respiratory tract usually leads to cell death,impairing respiratory function to cause severe ***,the diversity of clinical manifestations of SARS-CoV-2 infection increases the complexity and difficulty of viral infection prevention,and especially the high-frequency asymptomatic infection increases the risk of virus *** how SARS-CoV-2 affects apoptotic pathway may help to understand the pathological process of its ***,we uncovered SARS-CoV-2 imployed a distinct anti-apoptotic mechanism via its N *** found SARS-CoV-2 virus-like particles(trVLP)suppressed cell apoptosis,but the trVLP lacking N protein didn’*** study verified that N protein repressed cell apoptosis in cultured cells,human lung organoids and ***,N protein specifically interacted with anti-apoptotic protein MCL-1,and recruited a deubiquitinating enzyme USP15 to remove the K63-linked ubiquitination of MCL-1,which stabilized this protein and promoted it to hijack Bak in ***,N protein promoted the replications of IAV,DENV and ZIKV,and exacerbated death of IAV-infected mice,all of which could be blocked by a MCL-1 specific inhibitor,***,we identifed a distinct anti-apoptotic function of the N protein,through which it promoted viral *** may explain how SARS-CoV-2 effectively replicates in asymptomatic individuals without cuasing respiratory dysfunction,and indicate a risk of enhanced coinfection with other *** anticipate that abrogating the N/MCL-1-dominated apoptosis repression is conducive to the treatments of SARS-CoV-2 infection as well as coinfections with other viruses.

关键词： apo prevention promoted

White Radish polyphenols improve diet-induced obesity by regulating the metabolism of bile acids via gut-liver axis

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Food Science and Human Wellness 2024年

作者： Xiong Geng Weina Tian miaomiao Zhuang Rundong Wang Wenting Ma Ran Lin Huayan Shang Zhangfu Yu Ronghu shen Jianrong Li College of Food Science and Engineering， Bohai University Hangzhou Xiaoshan Agricultural Development CO.， Ltd

Natural plant or functional food-derived biologically active ingredients have recently raised considerable interest in their antiobesity effect. However， the antiobesity role of polyphenols of white radish roots remains unknown. This study examined the therapeutic efficacy and underlying mechanisms of polyphenols extract from white radish roots (RPE) on obese mice. RPE administration significantly decreased the weight gain in high-fat diet fed (HFD) mouse models. RPE intervention also increased serum glutathione transferase (GSH-Px) and superoxide dismutase (SOD) levels， and decreased malondialdehyde (MDA)， tumor necrosis factor-α (TNF-α) and lipopolysaccharide (LPS) levels in the HFD-fed mice. The intervention led to an escalation in the proportion of beneficial bacteria (Akkermansia， Clostridia)， and a corresponding decline in the fraction of harmful bacteria (Proteobacteria). According to liquid chromatography-mass spectrometry (LC-MS)-based gut metabolomics， the RPE intervention notably influenced several metabolic pathways， including those involved in protein digestion and absorption， central carbon metabolism related to cancer， and the biosynthesis of steroid hormones. Additionally， RPE treatment led to a reduction in the intestinal microbes possessing bile-salt hydrolase (BSH) activity， whereas increased the expression levels of the bile acid (BA) synthesis enzyme cholesterol 7α-hydroxylase (Cyp7a1). This led to increase hepatic production and fecal excretion of BAs， reduce hepatic cholesterol， and decrease lipogenesis. Treated HDF mice showed mitigation of hepatic steatosis and inflammation through gut-liver axis modulation by RPE interference. These findings together offer a significant understanding of the potential of RPE as an anti-obesity treatment and could assist in developing strategies for weight loss.

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Recent Advances in Spin-coating Precursor Mediated Chemical Vapor Deposition of Two-Dimensional Transition Metal Dichalcogenides

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Precision Chemistry 2024年第7期2卷 282-299页

作者： Dingyi shen Yejun Jin Zucheng Zhang Rong Song miaomiao Liu Wei Li Xin Li Ruixia Wu Bo Li Jia Li Bei Zhao Xidong Duan Hunan Key Laboratory of Two-Dimensional Materials State Key Laboratory for Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringHunan University410082 ChangshaChina Key Laboratory of Quantum Materials and Devices of Ministry of Education School of PhysicsSoutheast UniversityNanjing 211189China Key Laboratory of Two-Dimensional Materials State Key Laboratory for Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringHunan University410082 ChangshaChina

Two-dimensional(2D)transition metal dichalcogenides(TMDs)have garnered widespread interest in the scientific community and industry for their exceptional physical and chemistry properties,and great potential for applications in diverse fields including(opto)electronics,electrocatalysis,and energy *** vapor deposition(CVD)is one of the most compelling growth methods for the scalable growth of high-quality 2D ***,the conventional CVD process for synthesis of 2D TMDs still encounters significant challenges,primarily attributed to the high melting point of precursor powders,and achieving a uniform distribution of precursor atmosphere on the substrate to obtain controllable smaple domains is *** spin-coating precursor mediated chemical vapor deposition(SCVD)strategy provides refinement over traditional methods by eliminating the use of solid precursors and ensuring a more clean and uniform distribution of the growth material on the ***,the SCVD process allows fine-tuning of material thickness and purity by manipulating solution composition,concentration,and the spin coating *** Review presents a comprehensive summary of recent advances in controllable growth of 2D TMDs with a SCVD ***,a series of various liquid precursors,additives,source supply methods,and substrate engineering strategies for preparing atomically thin TMDs by SCVD are ***,2D TMDs heterostructures and novel doped TMDs fabricated through the SCVD method are ***,the current challenges and perspectives to synthesize 2D TMDs using SCVD are discussed.

关键词： Spin-coating Chemical vapor deposition Liquid precursor Substrate Two-dimensional materials Heterostructure Doping Film