检索结果-南通市图书馆

Magnetic anchor technique assisted endoscopic submucosal dissection for early esophageal cancer

World Journal of Gastrointestinal Endoscopy 2023年第10期15卷 584-592页

作者： Min Pan miao-miao zhang Shu-Qin Xu Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Thoracic Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Esophageal cancer has high incidence globally and is often diagnosed at an advanced *** the widespread application of endoscopic technologies,the need for early detection and diagnosis of esophageal cancer has gradually been *** submucosal dissection(ESD)has become the standard of care for managing early tumors of the esophagus,stomach,and ***,due to the steep learning curve,difficult operation,and technically demanding nature of the procedure,ESD has currently been committed to the development of various assistive *** To explore the feasibility and applicability of magnetic anchor technique(MAT)-assisted ESD for early esophageal *** Isolated pig esophagi were used as the experimental model,and the magnetic anchor device was designed by *** esophagi used were divided into two groups,namely the operational and control groups,and 10 endoscopists completed the *** two groups were evaluated for the following aspects:The total operative time,perforation rate,rate of whole mucosal resection,diameter of the peering mucosa,and scores of endoscopists’feelings with the procedure,including the convenience,mucosal surface exposure degree,and tissue *** addition,in the operational group,the soft tissue clip and the target magnet(TM)were connected by a thin wire through a small hole at the tail end of the *** gastroscopic guidance,the soft tissue clip was clamped to the edge of the lesioned mucosa,which was marked in *** changing the position of the anchor magnet(AM)outside the esophagus,the pulling force and pulling direction of the TM could be changed,thus exposing the mucosal peeling surface and assisting the *** Herein,each of the two groups comprised 10 isolated esophageal putative mucosal *** diameter of the peering mucosa did not significantly differ between the two groups(2.13±0.06 vs 2.15±0.06,P=0.882).The total operative time was shorter in the operational

关键词： Magnetic surgery Magnetic anchor technique Magnetic anchor device Endoscopic submucosal dissection Early esophageal cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomovars of Burkholderia cepacia Complex from Rice Rhizosphere and Clinic in China

引用

Rice science 2007年第3期14卷 229-234页

作者： Lou miao miao zhang Li xin Su Ting XIE Guan lin State Key Laboratory of Rice Biology Zhejiang UniversityHangzhou310029China

Burkholderia cepacia is regarded as a genetically distinct but phenotypically similar bacteria group referring to Burkholderia cepacia complex （Bcc）, which is found not only in clinic but also in rice growing environment. It is very important in microbial safety of rice for us to understand the genomovar status of Bcc. Genomovar analysis was performed among 87 Bcc isolates by means of Hae Ⅲ-recA RFLP assays and species-specific PCR tests. Three genomovars were found from the rice rhizosphere including Ⅰ, ⅢB and V, and genomovar V was predominant. Genomovars Ⅰ, ⅢA and ⅢB existed in the clinical samples, and genomovar ⅢA was the most popular. It showed that genomovar composition was different between the Bcc strains from the rice rhizosphere and clinical environment. Simultaneously, the results revealed the genetic diversity of Bcc strains from the rice rhizosphere, and genomovar Ⅲ referred as virulent species in clinic also existed in the rice rhizosphere.

关键词： Burkholderia cepacia complex rice rhizosphere clinic genomovars diversity biological safety biological control risk assessment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

和解还是上诉?——企业专利诉讼决策中的融资约束与声誉机制研究

引用

产业经济研究 2016年第5期 58-68页

作者：苗妙张新魏建华南理工大学经济与贸易学院广东广州510006 清华大学公共管理学院北京100084 山东大学经济研究院山东济南250100

知识经济时代,专利制度已成为我国实施创新发展战略的重要保障。提高专利纠纷的和解效率,对于降低企业诉讼成本、激发企业创新动力具有重要意义。基于我国2001—2014年A股上市公司专利诉讼案件的研究发现,融资约束和声誉机制在企业诉讼... 详细信息

知识经济时代,专利制度已成为我国实施创新发展战略的重要保障。提高专利纠纷的和解效率,对于降低企业诉讼成本、激发企业创新动力具有重要意义。基于我国2001—2014年A股上市公司专利诉讼案件的研究发现,融资约束和声誉机制在企业诉讼和解以及上诉决策中发挥着重要作用,但又有所差异。上市公司的融资约束程度越弱,当事人越不易和解且越倾向于上诉,而融资约束较强的上市公司出于经济利益最大化的考虑,同样也难以达成和解且倾向于上诉;注重声誉的公司在调解阶段往往不易和解,但在判决阶段也不轻易选择上诉。这一发现对厘清企业的专利诉讼动机,从司法层面促进专利纠纷的解决,设计与完善"激励相容"的司法调解制度和上诉制度具有重要的启示意义。

关键词：专利诉讼专利侵权专利挑战融资约束声誉机制和解决策上诉决策

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Decision making module based on stochastic magnetic tunnel junctions

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 202-209页

作者： Yifan miao Li Zhao Yajun zhang Zhe Yuan Center for Advanced Quantum Studies and Department of Physics Beijing Normal University Institute for Nanoelectric Devices and Quantum Computing Fudan University Interdisciplinary Center for Theoretical Physics and Information Sciences Fudan University

In biological neural systems, noise is ubiquitous but does not affect the correct decisions made in the complex cognitive ***-making in biological neural system is typically achieved by accumulating input information over a period of *** by recent developments in neurosciences, we design a decision-making module based on spintronic devices, utilizing superparamagnetic tunnel junctions as artificial neurons. The feasibility of this decision-making module is verified through circuit simulations. Taking a multi-layer perceptron as an example, the module significantly improves the accuracy of the perceptron in the handwritten digit recognition task. Furthermore, the spintronic decision-making module offers advantages over the conventional pooling methods, such as adaptive decision time, high performance and the absence of analog-to-digital conversion. The decision-making module is flexible to be integrated into artificial neural networks and provides a general yet effective solution to enhance performance against device noise.

关键词： neuromorphic computing spintronics magnetic tunnel junction neural networks

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Magnetic compression anastomosis for sigmoid stenosis treatment:A case report

引用

World Journal of Gastrointestinal Endoscopy 2023年第12期15卷 745-750页

作者： miao-miao zhang Yi Gao Xiao-Yang Ren Huan-Chen Sha Yi Lyu Fang-Fang Dong Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Gastrointestinal Surgery Affiliated Hospital of Guilin Medical UniversityGuilin 541001Guangxi Zhuang Autonomous RegionChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

BACKGROUND Endoscopic balloon dilation is a minimally invasive treatment for colorectal *** compression anastomosis can be applied against gastrointestinal *** combined with endoscopy,it offers a unique approach to the recanalization of colorectal *** SUMMARY We have reported here the case of a 53-year-old female patient who underwent a descending colostomy due to sigmoid *** fistula restoration was not possible in her due to sigmoid ***,endoscopicassisted magnetic compression anastomosis for sigmoid stenosis was performed,and the sigmoid stenosis was recanalized 15 d after the ***,a reduction colostomy was successfully performed after 10 *** This case report proposes a novel minimally invasive treatment approach for colorectal stenosis.

关键词： Colorectal stenosis Endoscopy Magnetic compression anastomosis Magnamosis Magnetosurgery Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A New Triterpenoid Saponin from Aidi Injection

引用

Chinese Herbal Medicines 2012年第2期4卷 84-86页

作者： miao-miao zhang Yan-li LIU Zhong CHEN Xiao-ran LI Qiong-ming XU Shi-lin YANG College of Pharmacy Soochow University Suzhou 215123 China

Objective To investigate the chemical constituents from Aidi *** The chemical constituents were isolated by chromatography on Sephadex LH-20 gel columns and reverse phase semi-preparative HPLC *** structures were identified by spectroscopic analysis(NMR and MS).Results Twenty-two compounds were isolated and identified to be 3-O-3′,4′-diacetyl-β-D-xylopyranosyl-6-O-β-D-glucopyranosyl- cycloastragenol(1),astragaloside IV(2),astragaloside II(3),astragaloside I(4),isoastragaloside I(5), acetylastragaloside I(6),ginsenosid Re(7),ginsenoside Rf(8),ginsenoside Rg1(9),ginsenoside Rb3(10), notoginsenoside R4(11),ginsenoside Rb1(12),ginsenoside Rc(13),ginsenoside Rb2(14),ginsenoside Rd(15), lucyoside H(16),3-O-β-D-glucopyranosyl(1→4)-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-α-L- arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside (17),3-O-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl[β-D-glucopyranosyl-(1→4)]-(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-arabinopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(18),syringin (19),elentheroside E(20),4-(1,2,3-trihydroxypropyl)-2,6-dimethoxyphenyl-1-O-β-D-glucopyranoside(21),and coniferin(22).Conclusion Compounds 1-6 are originated from Astragalus membranceus,compounds 7-18 are originated from Panax ginseng,and compounds 19-22 are originated from Acanthopanax senticosus by LC-MS *** 1 is a new compound.

关键词： Aidi Injection astragaloside I astragaloside II astragaloside IV 3-O-3′,4′-diacetyl-β-D-xylopyranosyl-6-O-β-D- glucopyranosyl-cycloastragenol

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

引用

Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli zhang Tian Li Jie miao Zhina zhang Mingxuan Yang Zhuoran Wang Bo Yang Jiawei zhang Haiting Li Qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

未来中国特高压电网结构形态与电源组成相互关系分析

引用

电力系统自动化 2018年第6期42卷 9-17页

作者：杨海涛吉平苗淼张桂红姜宁宋云亭电网安全与节能国家重点实验室(中国电力科学研究院有限公司) 北京市100192 国网青海省电力公司经济技术研究院青海省西宁市810008 国网青海省电力公司青海省西宁市810000 国网陕西省电力公司经济技术研究院陕西省西安市710065

基于中国电源和负荷分布的特点以及将来电源组成的变化,分析未来不同时期特高压电网结构形态与电源组成的相互关系,讨论未来中国特高压电网不同结构形态的适应性和安全性。结合中国间歇性电源不断增加和能源互联网发展趋势,展望2030年和... 详细信息

基于中国电源和负荷分布的特点以及将来电源组成的变化,分析未来不同时期特高压电网结构形态与电源组成的相互关系,讨论未来中国特高压电网不同结构形态的适应性和安全性。结合中国间歇性电源不断增加和能源互联网发展趋势,展望2030年和2050年前后过渡期和远景中国特高压电网需要的结构形态,指出将来特高压直流电网安全运行所面临的严峻挑战,以及中国特高压电网结构形态的变化趋势和面临的关键技术问题。

关键词：结构形态电源组成特高压交流电网特高压直流电网安全性能源互联网

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

引用

Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao zhang Li Jia Xiu-Jun Zhan Charity Ngina Qing-Rui zhang Xiao-Ge Li Qi-Bao Jiang Shi Bai miao-miao Jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

丹江口库区覆膜耕作土壤净氮矿化随夏玉米生长期的变化

引用

应用生态学报 2017年第2期28卷 581-588页

作者：王伟于兴修汉强徐苗苗任瑞张家鹏湖北大学资源环境学院/区域开发与环境响应湖北省重点实验室武汉430062

农田土壤净氮矿化对土壤氮素流失和农业非点源污染有重要影响.以丹江口库区五龙池小流域夏玉米黄棕壤为例,进行原位矿化试验,通过与无覆膜耕作土壤相比较,研究覆膜耕作条件下土壤净氮矿化在夏玉米生长期内的变化.结果表明:夏玉米整个生... 详细信息

农田土壤净氮矿化对土壤氮素流失和农业非点源污染有重要影响.以丹江口库区五龙池小流域夏玉米黄棕壤为例,进行原位矿化试验,通过与无覆膜耕作土壤相比较,研究覆膜耕作条件下土壤净氮矿化在夏玉米生长期内的变化.结果表明:夏玉米整个生长期内,覆膜耕作土壤净氨化量、净硝化量和净氮矿化量均明显高于无覆膜土壤,分别高6.63、12.96和19.59mg·kg^(-1);覆膜耕作土壤净氨化速率表现为在苗期较高、抽穗期最低、成熟期增至最高的变化特征,而土壤净硝化和净氮矿化速率均呈现苗期较高、拔节期最低、成熟期升至最高的变化过程;覆膜耕作土壤净氮矿化速率均与土壤全氮和NO_3^--N含量、土壤含水量之间呈显著线性关系.覆膜可有效调节土壤水热条件,促进土壤净氮矿化.

关键词：地膜覆盖夏玉米土壤净氮矿化树脂芯培养法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：