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Synthesis and Structural Analysis of LDH-SO4-CO3 Whisker

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Journal of Wuhan University of Technology(Materials Science) 2019年第5期34卷 1085-1088页

作者： WU jiansong YANG Yifeng School of Chemistry and Chemical Engineering Lingnan Normal UniversityZhanjiang 524048China School of Biological Science and Technology Lingnan Normal UniversityZhanjiang 524048China

High-quality LDH-SO4-CO3 whiskers were synthesized via liquid precipitation method using MgSO4·7 H2 O and Al2(SO4)3·18 H2O as precursors and Na2CO3-NaHCO3 buffer solution as precipitant. The influence of buffer solution concentration on the characteristics of the samples was investigated. The asgrown whiskers were characterized by X-ray diffraction, transmission electron microscopy, and BrunauerEmmett-Teller N2 specific surface area measurements. The results show that the buffer solution concentration has significant impact on whiskers with intercalated structure. The LDH-SO4-CO3 whiskers with well-defined geometry, distinct intercalated structure, decent quality, and excellent dispersing capability can be obtained under the following conditions: buffer solution volume ratio of 45%, reaction temperature of 83°C, and reaction time of 182 h. The obtained whiskers are well-crystallized and exhibit homogeneous morphology consisting of fiber bars.

关键词： whiskers LDH-SO4-CO3 synthesis structural analysis

BASES OF BIQUADRATIC POLYNOMIAL SPLINE SPACES OVER HIERARCHICAL T-MESHES

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Journal of Computational Mathematics 2017年第1期35卷 91-120页

作者： Fang Deng Chao Zeng Meng Wu jiansong Deng School of Mathematical Sciences University of Science and Technology of China Hefei China School of Mathematics Hefei University of Technology Hefei China

Basis functions of biquadratic polynomial spline spaces over hierarchical T-meshes are constructed. The basis functions are all tensor-product B-splines, which are linearly independent, nonnegative and complete. To make basis functions more efficient for geometric modeling, we also give out a new basis with the property of unit partition. Two preliminary applications are given to demonstrate that the new basis is efficient.

关键词： Spline spaces over T-meshes CVR graph Basis functions.

A survey on the local refinable splines

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Science China Mathematics 2016年第4期59卷 617-644页

作者： LI Xin CHEN FaLai KANG HongMei DENG jiansong School of Mathematical Sciences University of Science and Technology of China

This paper provides a survey of local refinable splines,including hierarchical B-splines,T-splines,polynomial splines over T-meshes,etc.,with a view to applications in geometric modeling and iso-geometric *** will identify the strengths and weaknesses of these methods and also offer suggestions for their using in geometric modeling and iso-geometric analysis.

关键词： geometric modeling isogeometric analysis B-splines hierarchical B-splines T-splines polynomial splines over hierarchical T-meshes(PHT-splines) locally refined(LR)B-splines local refinement

健脾化瘀解毒方调控PKA/NLRP3通路治疗胃癌前病变的机制

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中华中医药杂志 2024年第9期39卷 4605-4611页

作者：张丹倪家慧张喜沈阳刘伟方坚松潘华峰广州中医药大学广州510006 广州中医药大学第一附属医院岭南医学研究中心广州510006 南京中医药大学江苏省中医药防治肿瘤协同创新中心南京210023

目的:探讨健脾化瘀解毒方(JPHYJD)调控蛋白激酶A(PKA)/核苷酸结合寡聚化结构域样受体蛋白3(NLRP3)通路治疗胃癌前病变(GPL)的作用机制。方法:动物实验一:将60只小鼠随机分为空白组,模型组,JPHYJD高、低剂量组,维酶素组,分别进行处理后,H... 详细信息

目的:探讨健脾化瘀解毒方(JPHYJD)调控蛋白激酶A(PKA)/核苷酸结合寡聚化结构域样受体蛋白3(NLRP3)通路治疗胃癌前病变(GPL)的作用机制。方法:动物实验一:将60只小鼠随机分为空白组,模型组,JPHYJD高、低剂量组,维酶素组,分别进行处理后,HE染色观察胃黏膜病理改变,免疫荧光染色观察NLRP3、GSDMD表达。动物实验二:将60只小鼠随机分为空白组、模型组、H89组、模型+H89组、JPHYJD组、模型+H89+JPHYJD组,Western Blot检测GSDMD-N、Caspase-1、IL-1β表达。细胞实验一:THP-1细胞分为空白组、模型组和JPHYJD组,使用LPS+ATP造模后,JPHYJD组予含药血清处理。细胞实验二:分组同动物实验二,分别予以H89及JPHYJD含药血清处理。检测焦亡相关分子表达和PI染色。结果:动物实验中,与空白组比较,模型组出现GPL病变,NLRP3、GSDMD表达显著升高(P<0.01),JPHYJD可改善胃黏膜病变,显著抑制NLRP3、GSDMD表达(P<0.01,P<0.05);与空白组比较,模型组GSDMD-N、Caspase-1、IL-1β表达显著升高(P<0.01),JPHYJD可抑制其表达(P<0.01),模型+H89+JPHYJD组表达水平显著高于JPHYJD组(P<0.05)。细胞实验中,与空白组比较,模型组NLRP3、GSDMD-N、Caspase-1、IL-1β蛋白和mRNA表达显著升高,焦亡水平显著升高(P<0.01,P<0.05),JPHYJD可显著抑制上述分子表达,减少细胞焦亡(P<0.01);与空白组比较,模型组PKA降低,NLRP3、GSDMD-N、IL-1β升高,焦亡水平升高(P<0.01),JPHYJD可上调PKA,抑制NLRP3、GSDMD-N、IL-1β,减少细胞焦亡(P<0.01,P<0.05);与JPHYJD组比较,模型+H89+JPHYJD组PKA降低,NLRP3、GSDMD-N、IL-1β表达升高,焦亡水平升高(P<0.01)。结论:JPHYJD可通过调控PKA/NLRP3通路抑制细胞焦亡从而治疗GPL。

关键词：胃癌前病变健脾化瘀解毒方细胞焦亡核苷酸结合寡聚化结构域样受体蛋白3 蛋白激酶A

Synthesis of β-L-2',3'-Dideoxy-2'-fluoro-3'-hydroxy-methylarabinofuranosyl Pyrimidine Nucleosides

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Chinese Chemical Letters 2004年第2期15卷 135-137页

作者： jiansong XiaoLeiWANG YueJunXIANG ChungK.CHU RaymondSCHINAZI KangZHAO TheCollegeofPharmaceuticalsandBiotechnology TianjinUniversityTianjin300072 DepartmentofChemistry NewYorkUniversityNewYorkNY10003 DepartmentofMedicinalChemistry CollegeofPharmacyTheUniversityofGeorgiaAthensGA30602 CenterforAIDSresearch／VeteransAffairsMedicalCenter DecaturGA30033 andLaboratoryofBiochemicalPharmacology DepartmentofPediatricsEmoryUniversitySchoolofMedicineAtlanta.GA30322

Dideoxy-2'-fluoro-3'-hydroxymethylarabinofuranosylthymine 10 and cytosine 12 were synthesized from L-xylose and were found to be inactive against HIV-1 in acutely infected lymphocytes.

关键词： L-Nucleoside anti-HIV L-xylose synthesis.

单侧双通道内镜下经椎板间椎间融合治疗单节段退变性腰椎滑脱症的临床疗效分析

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中外医疗 2024年第10期43卷 54-58页

作者：韦波戚怀伟董剑嵩江苏省泰州市中西医结合医院骨伤科江苏泰州225300

目的探究单侧双通道内镜下经椎板间椎间融合治疗单节段退变性腰椎滑脱症的作用。方法方便选取2020年4月—2023年3月泰州市中西医结合医院收治的61例单节段退变性腰椎滑脱症患者作为研究对象,采用盲摸双色球法分为研究组(n=31)、参照组(n... 详细信息

目的探究单侧双通道内镜下经椎板间椎间融合治疗单节段退变性腰椎滑脱症的作用。方法方便选取2020年4月—2023年3月泰州市中西医结合医院收治的61例单节段退变性腰椎滑脱症患者作为研究对象,采用盲摸双色球法分为研究组(n=31)、参照组(n=30)。参照组行椎旁肌间隙入路经椎间孔减压椎间融合术治疗,研究组行单侧双通道内镜下经椎板间椎间融合术治疗。比较两组手术情况及术后疼痛程度和腰椎功能。结果研究组手术情况、腰椎功能情况均优于参照组,差异有统计学意义(P均<0.05)。术后3、7 d,研究组疼痛评分为(2.51±0.97)分、(0.95±0.28)分,低于参照组的(3.62±1.81)分、(1.80±0.41)分,差异有统计学意义(t=2.999、9.483,P均<0.05)。结论对比椎旁肌间隙入路经椎间孔减压椎间融合术,单侧双通道内镜下经椎板间椎间融合术治疗单节段退变性腰椎滑脱症患者的疗效更好,可改善手术情况相关指标,降低疼痛程度,提高腰椎功能。

关键词：单侧双通道内镜下经椎板间椎间融合术椎旁肌间隙入路经椎间孔减压椎间融合术单节段退变性腰椎滑脱症手术情况疼痛程度

Numerical Solution for Schrödinger Eigenvalue Problem Using Isogeometric Analysis on Implicit Domains

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Communications in Mathematics and Statistics 2020年第1期8卷 91-111页

作者： Ammar Qarariyah Fang Deng Tianhui Yang jiansong Deng School of Mathematical Sciences University of Science and Technology of ChinaHefei 230026China School of Mathematics and Statistics North China University of Water Resources and Electric PowerZhengzhou 450045HenanPeople’s Republic of China

We study the accuracy and performance of isogeometric analysis on implicit domains when solving time-independent Schrödinger *** construct weighted extended PHT-spline basis functions for analysis,and the domain is presented with same basis functions in implicit form excluding the need for a parameterization ***,an adaptive refinement process is formulated and discussed with *** constructed basis functions with cubic polynomials and only C^(1) continuity are enough to produce a higher continuous field approximation while maintaining the computational cost for the matrices as low as possible.A numerical implementation for the adaptivemethod is performed on Schrödinger eigenvalue problem with doublewell potential using 3 examples on different implicit *** convergence and performance results demonstrate the efficiency and accuracy of the approach.

关键词： Isogeometric analysis Finite element analysis PHT-splines Schrodinger equation Eigenvalue problems

涤痰汤联合抗生素治疗脑出血相关肺炎临床研究

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新中医 2024年第3期56卷 7-10页

作者：费娜裘垚张建松嵊州市中医院重症医学科浙江绍兴312499

目的:观察涤痰汤联合抗生素治疗脑出血相关肺炎的临床疗效。方法:选取80例脑出血相关肺炎患者,按随机数字表法分为观察组和对照组各40例。对照组根据患者情况选择敏感抗生素治疗,观察组在对照组基础上给予涤痰汤治疗。2组均治疗7 d。评... 详细信息

目的:观察涤痰汤联合抗生素治疗脑出血相关肺炎的临床疗效。方法:选取80例脑出血相关肺炎患者,按随机数字表法分为观察组和对照组各40例。对照组根据患者情况选择敏感抗生素治疗,观察组在对照组基础上给予涤痰汤治疗。2组均治疗7 d。评价2组临床疗效,比较2组体温、肺部影像学、白细胞计数(WBC)复常时间和肺部啰音消失时间,检测2组治疗前后超敏-C反应蛋白(hs-CRP)、降钙素原(PCT)及WBC水平,比较2组治疗前后临床肺部感染评分(CPIS)及神经功能缺损评分(NIHSS)评分。结果:观察组总有效率为95.00%,高于对照组77.50%(P<0.05)。观察组体温、肺部影像学、WBC复常时间和肺部啰音消失时间均短于对照组(P<0.05)。治疗后,2组hs-CRP、PCT、WBC水平均低于治疗前(P<0.05);且观察组hs-CRP、PCT、WBC水平均低于对照组(P<0.05)。治疗后,2组CPIS、NIHSS评分均低于治疗前(P<0.05),观察组CPIS、NIHSS评分均低于对照组(P<0.05)。结论:涤痰汤联合抗生素治疗脑出血相关肺炎患者,能缩短病程,恢复神经功能,降低炎症反应,提高临床疗效。

关键词：脑出血相关肺炎涤痰汤抗生素炎症因子神经功能临床肺部感染评分

A study on aquaculture industry regulations and policies of globally representative states

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Chinese Journal of Population,Resources and Environment 2013年第3期11卷 268-275页

作者： Yugui Zhu jiansong Chu College of Fisheries Ocean University of China

Aquaculture has a long history,and has achieved rapid development from 1950 to 2010,especially since the ***,aquaculture has also seen a series of problems ***,aquaculture interacts with the environment and *** development requires that close attention be paid to potential environmental and social impacts and their prevention or *** development and management of aquaculture is related closely with a variety of legal and institutional ***,aquaculture raises numerous legal and institutional *** paper explores actual legal and institutional practices of global representative aquaculture countries and provides a comprehensive account of the legislation and policies of different ***,this paper reveals that the optimal legal framework for aquaculture is in line with related international regulations(especially the soft laws)and strictly operational,and the corresponding policy framework should establish early access and warning,as well as post assessment and feedback mechanisms.

关键词： aquaculture regulation policy state