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Establishment and validation of a nomogram for predicting esophagogastric variceal bleeding in patients with liver cirrhosis

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World Journal of Gastroenterology 2025年第9期31卷 54-67页

作者： Lun-xi Liang xiao Liang Ya Zeng Fen Wang Xue-Ke Yu Department of Gastroenterology The Third Xiangya HospitalCentral South UniversityChangsha 410013Hunan ProvinceChina Department of Gastroenterology The Affiliated Changsha Central HospitalHengyang Medical SchoolUniversity of South ChinaChangsha 410008Hunan ProvinceChina Hunan Key Laboratory of Nonresolving Inflammation and Cancer The Third Xiangya HospitalCentral South UniversityChangsha 410006Hunan ProvinceChina School of Clinical Medicine Changsha Medical UniversityChangsha 410200Hunan ProvinceChina

BACKGROUND Patients with decompensated liver cirrhosis suffering from esophagogastric variceal bleeding(EGVB)face high *** To investigate the risk factors for EGVB in patients with liver cirrhosis and establish a diagnostic *** Patients with liver cirrhosis who met the inclusion criteria were randomly divided into training and validation cohorts in a 6:4 ratio in this retrospective *** analysis,least absolute shrinkage and selection operator regression,and multivariate analysis were employed to establish the nomogram *** curve,the area under the receiver operating characteristic curve(AUC),and decision curve analysis(DCA)were applied to assess the discrimination,accuracy,and clinical practicability of the nomogram,*** A total of 1115 patients were enrolled in this *** nomogram was established based on white blood cells(P<0.001),hemoglobin(P<0.001),fibrinogen(P<0.001),total bilirubin(P=0.007),activated partial thromboplastin time(P=0.002),total bile acid(P=0.012),and ascites(P=0.006).The calibration curve indicated that the actual observation results were in good agreement with the prediction results of the *** AUC values of the diagnostic model were 0.861 and 0.859 in the training and validation cohorts,respectively,which were higher than that of the aspartate aminotransferase-to-platelet ratio index,fibrosis index based on 4 factors,and aspartate aminotransferase-to-alanine aminotransferase ***,DCA indicated that the net benefit value of the model was higher than that of the other *** This research constructed and validated a nomogram with perfect performance for predicting EGVB events in patients with liver cirrhosis,which could help clinicians with timely diagnosis,individualized treatment,and follow-up.

关键词： Liver cirrhosis Esophagogastric variceal bleeding Diagnostic model Nomogram Retrospective study

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Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO_(2)

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu xiaoling Liu Biao Meng Tao Chen Yu Han Jun Wang Shibo xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816JiangsuChina Advanced Membranes and Porous Materials Center Physical Sciences and Engineering DivisionKing Abdullah University of Science and TechnologyThuwal 23955-6900Saudi Arabia Institute of Sustainability for Chemicals Energy and EnvironmentA*STAR(Agency for ScienceTechnology and Research)Jurong IslandSingapore 627833Singapore College of Materials Science and Engineering Sichuan UniversityChengdu 610065SichuanChina

The synergy of single atoms(SAs)and nanoparticles(NPs)has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction(CO_(2)RR);however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly(ionic liquids)(PIL)precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO_(2)into *** Ni K-edge X-ray absorption near-edge structure(XANES)spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO_(2),the coexistence of Ni SAs and NPs strengthened the CO_(2)activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO_(2)→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Single atom catalyst Synergy effect cO2 reduction Carbon catalyst Electrocatalysis

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2024 Annual Report of China Mineral Resources (copper, gold, coal, etc.)

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China Geology 2025年第1期8卷 235-236页

作者： Li-qiong Jia xi-jie Chen Zi-guo Hao Development and Research Center China Geological SurveyMinistry of Natural ResourcesBeijing 100037China

In October 2024,the Ministry of Natural Resources of PRC released the 2024 China Mineral Resources Report,which focuses on new progress since 2023 in the geological and mineral survey and evaluation,mineral resource exploration and development,mine ecological restoration,green mine construction,new changes in mineral resource policies and regulations,new measures in mineral resource management,new situations in scientific and technological innovation,as well as the new achievements of the international geological and mineral cooperation.

关键词： gold copper resource

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： xiao Liang xingping Quan xiaorui Geng Yujing Huang Yonghua Zhao Lei xi Zhen Yuan Ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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Design of Serially Concatenated Two-Level Polar Coded Modulation System with Low-Complexity

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China Communications 2025年第1期22卷 102-110页

作者： Zhou Lin Liao Guojun Xu Lei An Ran xie xianzhong Wang xi xiamen Key Laboratory of Mobile Multimedia Communications College of Information Science and EngineeringHuaqiao UniversityXiamen 361021China College of Computer Science and Technology Chongqing University of Posts and TelecommunicationsChongqing 400065China China Mobile Communications Group Fujian Co. Ltd.FuzhouFujian 350003China

Multilevel coding(MLC)is a commonly used polar coded modulation scheme,but challenging to implement in engineering due to its high complexity and long decoding delay for high-order *** address these limitations,a novel two-level serially concatenated MLC scheme,in which the bitlevels with similar reliability are bundled and transmitted together,is *** proposed scheme hierarchically protects the two bit-level sets:the bitlevel sets at the higher level are sufficiently reliable and do not require excessive resources for protection,whereas only the bit-level sets at the lower level are encoded by polar *** proposed scheme has the advantages of low power consumption,low delay and high ***,an optimized constellation signal labeling rule that can enhance the performance is ***,the superiority of the proposed scheme is validated through the theoretical analysis and simulation *** with the bit interleaving coding modulation(BICM)scheme,under 256-quadrature amplitude modulation(QAM),the proposed scheme attains a performance gain of 1.0 dB while reducing the decoding complexity by 54.55%.

关键词： bit-interleaved coded modulation high-order modulation multilevel coding polar codes

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杀虫药笔研制技术

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中华卫生杀虫药械 2002年第3期8卷 U005-U008页

作者：杨礼中彭熙绵毛占国广西玉林市保宁化工药业有限公司玉林537001 天津市南开区白蚁防治研究所天津300102

灭蟑螂、蚂蚁药粉笔,以下简称药笔,于1982年由中国科学院动物研究所毒理室研制,至今已在全国推广应用.现将研制问题总结如下:

关键词：杀虫药笔研制加工技术毒力

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T4b期胸段食管鳞癌同期放化疗疗效分析

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中华放射肿瘤学杂志 2018年第12期27卷 1056-1060页

作者：胡永红李巧巧习勉祝喻甲刘慧李群刘孟忠中山大学肿瘤防治中心放疗科华南肿瘤学国家重点实验室肿瘤医学协同创新中心、广东省食管癌研究所广州515060

目的研究拟分析T4b期食管鳞癌接受同期放化疗的临床疗效及治疗并发症,并探讨临床相关因素对预后的影响.方法回顾分析我院2010-2015年接受同期放化疗的143例T4b期胸段食管鳞癌患者,其中71%患者肿瘤侵犯气管或支气管,44%侵犯胸主动脉或... 详细信息

目的研究拟分析T4b期食管鳞癌接受同期放化疗的临床疗效及治疗并发症,并探讨临床相关因素对预后的影响.方法回顾分析我院2010-2015年接受同期放化疗的143例T4b期胸段食管鳞癌患者,其中71%患者肿瘤侵犯气管或支气管,44%侵犯胸主动脉或大血管.放疗中位剂量为60 Gy (44~68 Gy),常规分割,其中69例(48%)采用3DCRT,余74例(52%)采用IMRT;化疗均采用以铂类为基础的化疗方案.根据Kaplan-Meier法进行生存分析,Logrank检验差异,Cox回归模型进行多因素分析.结果全组患者的中位生存期为12. 2个月,2、3年生存率分别为34%、29%. 51例(36%)患者在治疗期间或放疗后3个月内发生≥2 级严重并发症,包括食管瘘42例、肺炎6例、食管出血3例.发生、未发生严重并发症患者的中位生存期分别为6. 9、20. 4个月(P<0. 01).多因素分析显示TNM分期、是否出现严重并发症是影响总生存的独立预后因素.结论 T4b期胸段食管鳞癌同期放化疗的疗效满意,但出现≥2级严重并发症的风险很高.

关键词：食管肿瘤/放化疗法预后

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Deciphering Water Oxidation Catalysts:The Dominant Role of Surface Chemistry over Reconstruction Degree in Activity Promotion

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Nano-Micro Letters 2025年第3期17卷 340-354页

作者： Li An Jianyi Li Yuanmiao Sun Jiamin Zhu Justin Zhu Yeow Seow Hong Zhang Nan Zhang Pinxian xi Zhichuan J.Xu Chun‑Hua Yan State Key Laboratory of Applied Organic Chemistry Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu ProvinceFrontiers Science Center for Rare IsotopesCollege of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000People’s Republic of China School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Faculty of Materials Science and Energy Engineering Institute of Technology for Carbon NeutralityShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055People’s Republic of China Key Laboratory of Electromagnetic Materials and Devices National Center for International Research On Photoelectric and Energy MaterialsSchool of Materials and EnergyElectron Microscopy CenterYunnan UniversityKunming 650091People’s Republic of China State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Baotou Research Institute of Rare EarthsBaotou 014030People’s Republic of China Beijing National Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsPKU‑HKU Joint Laboratory in Rare Earth Materials and Bioinorganic ChemistryPeking UniversityBeijing 100871People’s Republic of China

Water splitting hinges crucially on the availability of electrocatalysts for the oxygen evolution *** surface reconstruction has been widely observed in perovskite catalysts,and the reconstruction degree has been often correlated with the activity ***,a systematic study on the roles of Fe substitution in activation of perovskite LaNiO_(3)is *** substituting Fe content influences both current change tendency and surface reconstruction ***_(0.9)Fe_(0.1)O_(3)is found exhibiting a volcano-peak intrinsic activity in both pristine and reconstructed among all substituted perovskites in the LaNi_(1-x)Fe_(x)O_(3)(x=0.00,0.10,0.25,0.50,0.75,1.00)*** reconstructed LaNi_(0.9)Fe_(0.1)O_(3)shows a higher intrinsic activity than most reported NiFe-based ***,density functional theory calculations reveal that Fe substitution can lower the O 2p level,which thus stabilize lattice oxygen in LaNi0.9Fe0.1O3 and ensure its long-term ***,it is vital interesting that activity of the reconstructed catalysts relied more on the surface chemistry rather than the reconstruction *** effect of Fe on the degree of surface reconstruction of the perovskite is decoupled from that on its activity enhancement after surface *** finding showcases the importance to customize the surface chemistry of reconstructed catalysts for water oxidation.

关键词： Oxygen evolution reaction Perovskite oxides Doping Activation and reconstruction

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Emission characteristics of biogenic volatile organic compounds in a subtropical pristine forest of southern China

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Journal of Environmental Sciences 2025年第2期148卷 665-682页

作者： xi Chen Daocheng Gong Youjing Lin Qiao Xu Yujin Wang Shiwei Liu Qinqin Li Fangyuan Ma Jiangyong Li Shuo Deng Hao Wang Boguang Wang Institute for Environmental and Climate Research Jinan UniversityGuangzhou 511443China Guangdong Provincial Observation and Research Station for Atmospheric Environment and Carbon Neutrality in Nanling Forests China Australia-China Centre for Air Quality Science and Management(Guangdong) Guangzhou 511443China Hainan Provincial Ecological and Environmental Monitoring Center Haikou 571126China

Emission characteristics of biogenic volatile organic compounds(BVOCs)from dominant tree species in the subtropical pristine forests of China are extremely *** we conducted in situ field measurements of BVOCs emissions from representative mature evergreen trees by using dynamic branch enclosures at four altitude gradients(600-1690ma.s.l.)in the Nanling Mountains of southern *** characteristics as well as seasonal and altitudinal variations were *** emission rates and canopyscale emission factors were then *** showed that BVOCs emission intensities in the wet season were generally higher than those in the dry *** were the dominant BVOCs emitted from most broad-leaved trees,accounting for over 70%of the *** superba,Yushania basihirsuta and Altingia chinensis had relatively high emission intensities and secondary pollutant formation *** localized emission factors of isoprene were comparable to the defaults in the Model of Emissions of Gases and Aerosols fromNature(MEGAN),while emission factors of monoterpenes and sesquiterpenes were 2 to 58 times of those in the *** results can be used to update the current BVOCs emission inventory in MEGAN,thereby reducing the uncertainties of BVOCs emission estimations in forested regions of southern China.

关键词： Biogenic volatile organic compounds(BVOCs) Dynamic enclosure system Nanling Mountains Emission factors Emission rates Chemical reactivity

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Sub-6GHz Assisted mmWave Hybrid Beamforming with Self-Supervised Learning

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China Communications 2025年第1期22卷 158-170页

作者： Li Hongyao Gao Feifei Lin Bo Wu Huihui Gu Yuantao xi Jianxiang xi’an High Tech Institute Xi’an 710025China Tsinghua University Beijing 100084China

In this paper,we propose a sub-6GHz channel assisted hybrid beamforming(HBF)for mmWave system under both line-of-sight(LOS)and non-line-of-sight(NLOS)scenarios without mmWave channel ***,we resort to the selfsupervised approach to eliminate the need for labels,thus avoiding the accompanied high cost of data collection and *** first construct the dense connection network(DCnet)with three modules:the feature extraction module for extracting channel characteristic from a large amount of channel data,the feature fusion module for combining multidimensional features,and the prediction module for generating the HBF ***,we establish a lightweight network architecture,named as LDnet,to reduce the number of model parameters and computational *** proposed sub-6GHz assisted approach eliminates mmWave pilot resources compared to the method using mmWave channel information *** simulation results indicate that the proposed DCnet and LDnet can achieve the spectral efficiency that is superior to the traditional orthogonal matching pursuit(OMP)algorithm by 13.66% and 10.44% under LOS scenarios and by 32.35% and 27.75% under NLOS scenarios,***,the LDnet achieves 98.52% reduction in the number of model parameters and 22.93% reduction in computational complexity compared to DCnet.

关键词： hybrid beamforming mmWave selfsupervised learning sub-6GHz assisted mmWave transmission sub-6GHz channel

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