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Chronic gastrointestinal symptoms and quality of life in the Korean population

World Journal of Gastroenterology 2008年第41期14卷 6388-6394页

作者： Jeong-Jo Jeong Myung-Gyu choi Young-Seok cho Seung-Geun Lee Jung-Hwan Oh Jae-Myung Park Yu-kyung cho In-Seok Lee Sang-Woo Kim Sok-Won Han Kyu-Yong choi In-Sik Chung Department of Internal Medicine the Catholic University of Korea Department of Biostatistics University of North Carolina at Chapel Hill NC

AIM： To evaluate the prevalence of chronic gastroin- testinal symptoms and their impact on health-related quality of life （HRQOL） in the Korean population. METHODS： A cross-sectional survey, using a reliable and valid Rome I] based questionnaire, was per- formed on randomly selected residents, between 18 and 69 years in age. All respondents were interviewed at their homes or offices by a team of interviewers. The impact of chronic gastrointestinal symptoms on HRQOL was assessed using the Korean version of the 36-item Short-Form general health survey （SF-36）. RESULTS： Of the 1807 eligible subjects, 1417 （78.4%： male 762; female 655） were surveyed. Out of the respondents, 18.6% exhibited at least one chronic gastrointestinal symptom. The prevalence of gastro- esophageal reflux disease （GERD）, defined as heart- burn and/or acid regurgitation experienced at least weekly, was 3.5% （95% CI, 2.6-4.5）. The prevalence of uninvestigated dyspepsia, irritable bowel syndrome （IBS） and chronic constipation based on Rome Ⅱ criteria were 11.7% （95% CI, 10.1-13.5）, 2.2% （95% CI, 1.5-3.1）, and 2.6% （95% CI, 1.8-3.5） respectively. Compared with subjects without chronic gastrointesti- nal symptoms （n = 1153）, those with GERD （n = 50）, uninvestigated dyspepsia （n = 166） and IBS （n = 31） had significantly worse scores on most domains of the SF-36 scales. CONCLUSION： The prevalence of GERD, uninvesti- gated dyspepsia and IBS were 3.5%, 11.7% and 2.2% respectively, in the Korean population. The health- related quality of life was significantly impaired in subjects with GERD, uninvestigated dyspepsia and IBS in this community.

关键词： Chronic gastrointestinal symptom Gastroesophageal reflux disease Dyspepsia Irritable bowel syndrome Qaulibl of life

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Transient Hypertensive Response to CO<sub>2</sub>Aortography in a Patient with Pheochromocytoma

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Open Journal of Radiology 2015年第1期5卷 1-7页

作者： Nimesh Patel kyung J. cho University of michigan Medical School Ann Arbor MI USA Department of Radiology Division of Vascular & Interventional Radiology University of Michigan Health System Ann Arbor MI USA

We report on a 15-year-old male with 4-year history of hypertension and retroperitoneal masses referred to Interventional Radiology to evaluate the nature of the persistent masses and renal artery stenosis. Angiographic evaluation began with CO2aortogram during which the patient had a hypertensive response with bradycardia and arrhythmia to the intra-aortic injection of CO2. His hypertension, bradycardia, and arrhythmia responded to an intravenous nitroglycerin drip without administration of alpha or beta blockers. Due to this response and neovascularity of the mass, selective venous sampling of catecholamines and renin was performed which confirmed functioning paragangliomas and hemodynamically significant stenosis of left accessory renal artery, respectively. This is the first known case of hypertensive response to CO2 aortography in a patient with unsuspected functioning paragangliomas. We propose that patients with known or suspected diagnosis of catecholamine-secreting tumors undergoing CO2 angiography should be considered for pre-procedural treatment with alpha and beta blockage or have the appropriate medication on hand with close monitoring in the event of hypertensive response.

关键词： CO2 Aortography Paraganglioma Caval Venous Sampling Renal Artery Stenosis

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Association of chronic viral hepatitis B with insulin resistance

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World Journal of Gastroenterology 2012年第42期18卷 6120-6126页

作者： Jeong Gyu Lee Sangyeoup Lee Yun Jin Kim Byung Mann cho Joo Sung Park Hyung Hoi Kim JaeHun Cheong Dong Wook Jeong Yu Hyun Lee Young Hye cho mi Jin Bae Eun Jung choi Department of Family Medicine Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Family Medicine Medical Research InstitutePusan National University HospitalBusan 602-739South Korea Medical Education Unit Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Family Medicine Clinic Yangsan Pusan National University HospitalBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Preventive Medicine and Occupational Medicine Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Family Medicine Dong-A University Medical CenterBusan 602-715South Korea Department of Laboratory Medicine Biomedical Informatics UnitPusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Molecular Biology College of Natural SciencesPusan National UniversityBusan 602-739South Korea

AIM:To investigate the relationship between chronic viral hepatitis B(CVHB) and insulin resistance(IR) in Korean ***:A total of 7880 adults(3851 men,4029 women) who underwent a comprehensive medical examination were enrolled in this *** diagnosed with either diabetes mellitus,or any other disorder that could influence their insulin sensitivity,were ***,metabolic risk factors,hepatitis B surface antigen,hepatitis B surface antibody,hepatitis B core antibody,fasting plasma glucose and insulin were measured for all *** model assessment(HOMA),quantitative insulin check index(QUICKI),and Mf fm index were used for determining insulin *** participant was categorized into a negative,recovery,or CVHB *** compare variables between groups,a t-test and/or one-way analysis of variance were *** correlation coefficients were computed to present the association between insulin resistance and other *** logistic regression analysis was used to assess the independent association between CVHB and ***:The mean age of men and women were 48.9 and 48.6 years,*** in the CVHB group had significantly higher waist circumference [(86.0 ± 7.7 cm vs 87.3 ± 7.8 cm,P = 0.004 in men),(78.3 ± 8.6 cm vs 80.5 ± 8.5 cm,P mi)(r = 0.378,P cholesterol(r = 0.134,P < 0.00

关键词： Hepatitis B Insulin resistance Diabetes mellitus type 2 Metabolic syndrome

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THE EFFECTIVNE SSS AND LImiTATION OF MOBILE CT

THE EFFECTIVNE SSS AND LIMITATION OF MOBILE CT

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中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： kyung Gi cho Department of Neurosurgery Bundang CHA Hospital CHA University

＜正＞INTRODUCTION: We report our preliminary experience in a prospective series of patients with regard to feasibility, work flow, image quality and its limitation using a a portable CT scanner （CereTom? Dimensions...

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The relationship between cardiovascular disease risk factors and gender

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Health 2012年第6期4卷 309-315页

作者： Chung-min cho Young-mi Lee College of Nursing Science Sungshin Women’s University Seoul Korea Department of Nursing Hanbuk University Gyeonggi-do Korea

The purpose of this study was to investigate the relationship between three socioeconomic sta- tuses and five behavior-related cardiovascular risk factors by gender, based on data from the Third Korea National Health and Nutrition Examination III. Data from 4556 people were analyzed. The propensity toward obesity, hypercholesterolemia, and physical inactivity was significantly higher in women than in men. Hypertension and smoking were significantly more prevalent in men than in women. The differences in the prevalence of cardiovascular disease risk factors by gender is important and should be considered when developing programs to reduce the incidence of cardiovascular diseases.

关键词： Cardiovascular Disease Risk Factor Gender

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Self Localization Method Using Parallel Projection Model for Mobile Sensor in Navigation Applications

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Journal of Computer Science & Technology 2009年第3期24卷 588-603页

作者： Shung Han cho Yuntai Kyong Sangjin Hong We-Duke cho Department of Electrical and Computer Engineering Stony Brook University- SUNY Stony Brook NY U.S.A. Department of Electronics Engineering College of Information Technology Ajou University Suwon Korea

This paper presents a novel self localization method using parallel projection model for mobile sensor in navigation applications. The algorithm estimates the coordinate and the orientation of mobile sensor using projected references on visual image. The proposed method considers the lens non-linearity of the camera and compensates the distortion by using a calibration table. The method determines the coordinates and orientations with iterative process, which is very accurate with low computational demand. We identify various sources of error on the coordinate and orientation estimations, and present both static sensitivity analysis of the algorithm and dynamic behavior of the mobile sensor. The algorithm can be utilized in mobile robot navigation as well as positioning application where accurate self localization is necessary.

关键词： mobile sensors localization parallel projection model visual processing

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Predicting tumor response after preoperative chemoradiation using clinical parameters in rectal cancer

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World Journal of Gastroenterology 2011年第48期17卷 5310-5316页

作者： Chan Ho Park Hee Cheol Kim Yong Beom cho Seong Hyeon Yun Woo Yong Lee Young Suk Park Doo Ho choi Ho-kyung Chun Departmentof Surgery Samsung Medical Center Sungkyunkwan Univer-sity School of Medicine Irwon-dong 50 Gangnam-gu Seoul135-710 South Korea Division of Hematology-Oncology Depart-ment of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Irwon-dong 50 Gangnam-guSeoul 135-710 South Korea Department of Radiation Oncology SamsungMedical Center Sungkyunkwan University School of MedicineIrwon-dong 50 Gangnam-gu Seoul 135-710 South Korea

AIM: To evaluate the clinical parameters and identify a better method of predicting pathological complete response (pCR). METHODS: We enrolled 249 patients from a database of 544 consecutive rectal cancer patients who underwent surgical resection after preoperative chemoradiation therapy (PCRT). A retrospective review of morphological characteristics was then performed to collect data regarding rectal examination findings. A scoring model to predict pCR was then created. To validate the ability of the scoring model to predict complete ***: Seventy patients (12.9%) achieved a pCR. A multivariate analysis found that pre-CRT movability (P = 0.024), post-CRT size (P = 0.018), post-CRT morphology (P = 0.023), and gross change (P = 0.009) were independent predictors of pCR. The accuracy of the scoring model was 76.8% for predicting pCR with the threshold set at 4.5. In the validation set, the accuracy was 86.7%. CONCLUSION: Gross changes and morphological findings are important predictors of pathological response. Accordingly, PCRT response is best predicted by a combination of clinical, laboratory and metabolic information.

关键词： Rectal cancer Preoperative chemoradiotherapy Downstaging Tumor regression Validation

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Prediction of the indication criteria for endoscopic resection of early gastric cancer

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World Journal of Gastroenterology 2015年第39期21卷 11160-11167页

作者： Jae Hyun Park Si Hyung Lee Joon Mo Park Chan Seo Park kyung Sik Park Eun Soo Kim Kwang Bum cho Department of Internal Medicine Yeungnam University College of Medicine Department of Internal Medicine Keimyung University College of Medicine

AIM: To find risk factors of lymph node metastasis(LNM) in early gastric cancer(EGC) and to find proper endoscopic therapy indication in ***: We retrospectively reviewed the 2270 patients who underwent curative operation for EGC from January 2001 to December 2008. EGC was defined as malignant lesions that do not invade beyond the submucosal layer of the stomach wall irrespective of presence of lymph node ***: Among 2270 enrolled patients, LNM was observed in 217(9%) patients. LNM in intramucosal(M) cancer and submucosal(SM) cancer was detectedin 3 8( 2. 8 %, 3 8 / 1 3 4 0) patients and 1 7 9(19%, 179/930) patients, respectively. In univariate analysis, the risk factors for LNM in EGC were size of tumor, Lauren classification, ulcer, lymphatic invasion, vascular invasion, and depth of invasion. However, in multivariate analysis, size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in EGC. Size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in cases of intramucosal cancer and submucosal cancer. In particular, there was no lymph node metastasis in cases of well differentiated early gastric cancer below 1 cm in size without ulcer regardless of lymphovascular ***: Tumor size, perilymphatic-vascular invasion, and depth of invasion were risk factors for LNM in EGC. There was no LNM in EGC below 1 cmregardless risk factors.

关键词： Early gastric cancer Lymph node metastasis Endosco

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Free Energy Level Correction by Monte Carlo Resampling with Weighted Histogram Analysis Method

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Chinese Journal of Chemical Physics 2020年第2期33卷 183-195,I0003,I0010-I0017页

作者： Seyoung Chung Sun mi choi Wook Lee Kwang Hyun cho Young min Rhee Department of Chemistry Pohang University of Science and TechnologyPohang 37673Korea Department of Chemistry Korea Advanced Institute of Science and TechnologyDaejeon 34141Korea

Free energy calculations may provide vital information for studying various chemical and biological *** mechanical methods are required to accurately describe interaction energies,but their computations are often too demanding for conformational *** a remedy,level correction schemes that allow calculating high level free energies based on conformations from lower level simulations have been ***,we present a variation of a Monte Carlo(MC)resampling approach in relation to the weighted histogram analysis method(WHAM).We show that our scheme can generate free energy surfaces that can practically converge to the exact one with sufficient sampling,and that it treats cases with insufficient sampling in a more stable manner than the conventional WHAM-based level correction *** can also provide a guide for checking the uncertainty of the levelcorrected surface and a well-defined criterion for deciding the extent of smoothing on the free energy surface for its visual *** demonstrate these aspects by obtaining the free energy maps associated with the alanine dipeptide and proton transfer network of the KillerRed protein in explicit water,and exemplify that the MC resampled WHAM scheme can be a practical tool for producing free energy surfaces of realistic systems.

关键词： Free energy level correction Weighted histogram analysis method Monte Carlo resampling

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Extraction of Behavioural Requirements for Simulation-based Performance Evaluation of Manufacturing Systems

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Journal of Systems Science and Systems Engineering 2019年第5期28卷 555-579页

作者： Junpil Kim Hyunbo cho Department of Industrial and Management Engineering Pohang University of Science and Technology(POSTECH) Republic of Korea

A simulation model enables manufacturers to accurately evaluate the performance of their manufacturing systems.A vital input to build simulation models of manufacturing systems is the system behaviour,which is modelled based on extensive data on manufacturing systems and their ***,for outsourced manufacturing systems,data provided from external suppliers to manufacturers are generally limited and ***,a solution is required to identify and secure system behaviour from available *** propose herein a behaviour extraction process along with detailed activities and diagrams to extract system behaviour from limited *** using the systems engineering standard ANSI/EIA-632,the proposed process systematically restructures available data on a manufacturing system and its elements and then provides complete system behaviour to build a simulation model.A case study on a cooling water control system in a hot strip mill convincingly demonstrates the applicability and effectiveness of the proposed process.

关键词： Behaviour extraction manufacturing systems simulation model system behaviour systems engineering

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