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Pregnancy Preferences in Females of Reproductive Age with Sickle Cell Disease at Laquintinie Hospital: A Cross-Sectional Analysis

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 744-757页

作者： Eposse Ekoube Charlotte Jeannette Disso Massako Mangala Fulbert Nkwele Mandeng Ma Linwa Edgar Puepi Djike Yolande merlin Boten Bounyom Erero F. Njiengwe Épée Patricia Hassanatou Iyawa Dora Mbonjo Bitsie Emmanuel Heles Nsang Soumaiyatou Abba Ngo Linwa Esther Eleonore Ndolo Kondo Astrid Grâce Tocki Toutou Moustapha Bilkissou Essome Henri Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Paediatric Unit Douala Laquintinie Hospital Douala Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon

Introduction: Females with sickle cell disease (SCD), despite having a delayed pubertal development, are subject to many worries relating to their abilities to conceive, their capacity to maintain a maternofetal-risk-free pregnancy till term and give birth to healthy children without sickle cell disease. Knowing that unplanned pregnancies are more likely to increase maternofetal morbidity and mortality, we sought out to explore the pregnancy preferences in female patients with sickle cell disease to promote healthy conception and childbirth in this vulnerable population. Methodology: We conducted a cross-sectional study involving female patients of child-bearing age with sickle cell disease followed at Laquintinie Hospital Douala or who were members of a local sickle cell association. Pregnancy preferences were determined using the Desire to Avoid Pregnancy (DAP) scale. Factors associated with pregnancy preferences were determined using multivariable linear regression model. Threshold for significance was set at p Results: Seventy-seven patients were included with a mean age of 24.71 ± 5.53 years. Forty patients (51.95%) had one sexual partner and thirteen women (32.5%) used contraceptive methods. Most patients (46.0%) responded “Strongly Agree” or “Agree” to the statement “it would be a good thing for me if I became pregnant in the next 3 months”. The mean DAP score was 1.63 ± 0.91 [1.28 ± 0.82 in those who had a sexual partner and 1.99 ± 0.86 in those who had no sexual partner]. Factors that were positively associated with DAP score were students (b = 0.32, 95% CI [0.21, 0.95], p = 0.003), monthly income ≥ 100,000 FCFA (b = 0.24, 95% CI [0.07, 0.81], p = 0.022), and not having a sexual partner (b = 0.26, 95% CI [0.11, 0.85], p = 0.012). Conclusion: Most female patients with SCD have a low desire to avoid pregnancy. This is especially true for patients who are not students, have a partner and have a low monthly income.

关键词： Pregnancy Preferences Sickle Cell Disease Laquintinie Hospital Cameroun

基于YOLOv3的袋式除尘器滤袋破损自动检测方法

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烧结球团 2024年第1期49卷 99-105页

作者：李旭东廖婷婷乐文毅曾小信陈思墨李宗平中冶长天国际工程有限责任公司工程技术研究中心湖南长沙410205 中冶长天国际工程有限责任公司国家烧结球团装备系统工程技术研究中心湖南长沙410205

干式除尘装置中袋式除尘器的滤袋在长时间使用后会出现破损,造成能源消耗增加、除尘效率降低、污染环境等严重问题。为此,本文采用在除尘舱室处搭建粉尘烟雾检测摄像头,并基于YOLOv3算法检测袋口烟雾的泄漏情况。试验检测步骤:①根据真... 详细信息

干式除尘装置中袋式除尘器的滤袋在长时间使用后会出现破损,造成能源消耗增加、除尘效率降低、污染环境等严重问题。为此,本文采用在除尘舱室处搭建粉尘烟雾检测摄像头,并基于YOLOv3算法检测袋口烟雾的泄漏情况。试验检测步骤:①根据真实除尘舱室尺寸设计袋式除尘器袋口烟雾泄漏实验室平台,采集不同洞口烟雾泄漏的图像数据;②使用软件标注这些图像数据;③搭建Darknet深度学习框架,采用YOLOv3算法对图像数据进行训练,并依据模型计算结果识别破袋情况。结果表明:模型对于批量图像的识别准确率能达到91%以上,对于连续视频的识别准确率可达95.65%。本文系统可以减少除尘器运行中的人工检测,降低工厂人力资源成本和工人劳动强度,可以避免生产中的安全隐患和损失,可以为工厂的生产安全及定期维护提供技术指导,也为全厂智能化生产提供了有效的方案。

关键词：烟气除尘布袋除尘器机器学习图片识别 YOLOv3

Radical Hysterectomy in Cervical Cancer: Patients’ Epidemiological and Clinical Profiles and Perioperative Outcome in Two Referral Hospitals in Cameroon

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Open Journal of Obstetrics and Gynecology 2024年第3期14卷 466-479页

作者： Théophile Njamen Nana Robert Tchounzou Fulbert Nkwele Mangala Alphonse Ngalame Henri Essome Sedrick Tiokeng Sidonie Noa Ananga Andrew Tassang Humphry Tatah Neng Isaac Mboh Eyong Gaetan Andre Wambo simo Felix Adolphe Elong Fidelia Kobenge Mbi Junior Cédric Nana Njamen Charlotte Tchente Nguefack Thomas Obinchemti Egbe Gregory Ekane Halle Emile Telesphore Mboudou Marcellin Ngowe Ngowe Department of Obstetrics and Gynaecology Douala General Hospital Douala Cameroon Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Buea Buea Cameroon Department of Obstetrics and Gynaecology Douala Gynaeco-Obstetric and Pediatric Hospital Douala Cameroon Department of Surgery and Specialties Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Pathology Douala General Hospital Douala Cameroon Faculté Des Sciences De La Santé Université Joseph Kizerbo Ouagadougou Burkina Faso

Background: Cervical cancer (CC) is one of the most frequent cancers and the leading cause of death from gynecological cancer in Low and middle income countries, Cameroon inclusive. Surgery is the primary treatment modality when the disease is diagnosed at early stage. Radical hysterectomy in cervical cancer has not been evaluated in recent years in Cameroon. The purpose of this study is thus to evaluate the epidemiological and clinical features and short term outcomes of patients who underwent surgery. Patients and methods: This retrospective study was conducted at the Douala Gynaeco-obstetric and Pediatric Hospital and the Douala General Hospital. Cervical cancer patients who underwent Radical hysterectomy between January 2015 and December 2020 were included. A pre-established data collection tool was used to record socio-demographic, clinical and outcomes information from patients’ files;additional outcome information was obtained from phone calls. Descriptive analysis was done using the SPSS version 26. Bivariate analysis was used to determine associations between disease and patients characteristics and occurrence of adverse postoperative outcome. P value of 0.05 was considered. Results: Sixty one patients were enrolled. Their ages ranged from 33 to 74 years with a mean age of 51.95 ± 10.29 years. Over 85% of women were married, 65.57% were unemployed and 86.88% were multiparous. Only 28% had never done cervical cancer screening. Most patients had stage IB1 to IB2 stage disease (57.1%). Less than 9% underwent radical hysterectomy and 8 of those (13.11%) suffered intraoperative complications. Twenty-five patients (40.98%) presented immediate and short term complications. There was no significant association between the disease or patients’ characteristics and adverse outcomes. Conclusion: Cervical cancer patients are relatively young in our settings and only 9% of them reach the hospital at early stage. Postoperative adverse outcomes rate is higher than that rep

关键词： Cervical Cancer Radical Hysterectomy Epidemiological and Clinical Profiles Outcomes Cameroon

Granitic inselbergs of Lara(Panafrican Chain,Far-North Cameroon):Assets for the implementation of geotourism in Mountainous region

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Journal of Mountain Science 2022年第11期19卷 3192-3212页

作者： ZANGMO TEFOGOUM Ghislain NOUHOU DAMA Zouyane Hyacinthe GOUNTIÉDEDZO merlin MAFO DONGMO Irène Department of Earth Sciences de la Terre Faculty of ScienceUniversity of MarouaP.O.Box 814 MarouaCameroon Department of Life and Earth Sciences High Teacher Training CollegeUniversity of MarouaP.O.Box 55MarouaCameroon

The locality of Lara(Far-North Region,Cameroon)is made up of a pediplain strewn with coalescent *** interaction of internal and external geological processes has contributed to transform the latter into inselbergs,whose geotouristic values are yet to be *** and laboratory work enabled us to select the geomorphosites through their aesthetic value(particular size and shape)and,geomorphological and geological ***,it permitted to study and map the geomorphosites using Optic Microscope,Google Earth,GIS software and many other ***,four inselbergs have been selected and studied in the locality of *** petrographic study of these inselbergs shows that granites are the main components of inselbergs and they present a fine to coarse-grained texture,materialized by quartz,micas,plagioclases and alkali feldspars(white and pink in colour).Inselbergs exhibit vertical and parallel networks of diaclases giving them a stratified appearance in some *** addition,on some inselberg limbs and piedmonts,are built tors which contribute to their *** tops of inselbergs,are embellished by several alluring pedestal *** their flanks,shelters of various shapes and sizes(about 12 m length)have developed through the heaps of blocks *** the ten shelters selected,some have a fairly high cultural value as they are sacred places for the local ***,Lara's granitic inselbergs include enclaves(cognate enclaves and xenocrysts)that also significantly improve their geoheritage *** are landforms with high education and aesthetic value that attracted a larger local and foreign population of about 863 visitors between *** constitute an exceptional geoheritage that could attract more tourists in the locality of Lara;but the promotion of geotourism is needed through interpretative panels,marketing of geomorphosites through leaflets,web,media,and geotours,to mention a few.

关键词： Lara Inselbergs Granite geoheritage Geotouristic activities

Evaluation of the diuretic effects of crude stem bark extraction of Zanthoxylum heitzii(Rutaceae) in Wistar rats

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Journal of Integrative Medicine 2015年第5期13卷 326-335页

作者： Fidèle Ntchapda Maguirgue Kakesse Michel Archange tagne Fokam Olivier Mbouemboue Pancha Djedouboum Abakar Théophile Dimo Department of Biological Sciences Faculty of Science University of Ngaoundéré Cameroon Department of Biomedical Sciences Faculty of Science University of Ngaoundéré Cameroon Department of Animal Biology and Physiology Faculty of Science University of Yaoundé I

OBJECTIVE： Zanthoxylum heitzii is a medicinal plant widely used in central Africa for the treatment of many diseases, especially cardiovascular diseases and hypertension. The diuretic effects of crude stern bark extraction were determined and its safety in rats was evaluated. METHODS： The diuretic effects of crude stem bark extraction of Z. heitzii were investigated in Wistar rats （250 g ＋ 10 g） of both sexes. The crude stem bark extraction of Z. heitzii at the doses of 225, 300 and 375 mg/kg was administered to rats at 5 mL/kg body weight. Urine volume was determined 1, 2, 3, 4, 5, 6 and 24 h after administration of the extract. Kinetics of electrolyte elimination in response to a single oral administration dose of acute treatment was measured. The experiments were performed under the same conditions with two synthetic pharmacological diuretics considered as reference （furosemide and hydrochlorothiazide）. Urinary and plasma concentrations of sodium and potassium ions were determined using flame photometry. Concentrations of creatinine, urea, glucose, albumin and electrolytes in the plasma and urine samples were evaluated using a two-way digital bidirectional spectrophotometer. The osmolarity of plasma and urine samples was measured by cytometry using an osmometer. Aldosterone was measured by radioimmunoassay. RESULTS： The plant extract accelerated the elimination of overloaded fluid and increased urine volume and the excretion of Na＋, K＋ and CI 24 h after administration （P〈0.05）. The increase in elimination of Na＋, K＋, and Cl- induced by the extract caused alkalinization of the urine, and showed a strong inhibitory effect on carbonic anhydrase and saluretic. These effects were mainly observed at the dose of 375 mg/kg. At the maximum diuretic response, urinary osmolarity decreased significantly （P 〈 0.05） when compared to controls. The stability of aldosterone level, the absence of correlation with the plasma levels of Na＋, and increased clearance of free water in t

关键词： Zanthoxylum heitzii diuretic urine volume urine pH electrolytes temperature rectal

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太阳能电梯的研究与开发

太阳能学报 2020年第7期41卷 158-164页

作者：徐政李旭李博 Makimattila simo 清华大学深圳国际研究生院电力系统国家重点实验室深圳研究室深圳518055 通力电梯有限公司昆山215300

针对老楼加装电梯改造工程中面临的配电线路可能短时超载、建设与运行费用分摊协调困难等问题,研究光伏+储能的太阳能电梯系统方案,开发对原电梯控制系统无任何影响的太阳能电梯控制器,实现光伏优先、电网补充的双电源供电模式。光伏阵... 详细信息

针对老楼加装电梯改造工程中面临的配电线路可能短时超载、建设与运行费用分摊协调困难等问题,研究光伏+储能的太阳能电梯系统方案,开发对原电梯控制系统无任何影响的太阳能电梯控制器,实现光伏优先、电网补充的双电源供电模式。光伏阵列对配套的蓄电池充电,提供电梯运行所需的电能;在电梯运行过程中,蓄电池既能及时提供大功率驱动电能消除对配电线路的冲击,又能高效吸收回馈电能降低系统的能耗,并且保证停电时电梯的正常运行。实验结果表明,光伏发电效率高,电机驱动与能量回馈动态特性良好,电梯运行平稳。

关键词：太阳能发电电梯变频器电池管理系统节能

Antioxidant activity of dichloromethane fraction of Dichrocephala integrifolia in Salmonella typhi-infected rats

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Journal of Integrative Medicine 2019年第6期17卷 438-445页

作者： Gaetan Olivier Fankem Michel Archange Fokam tagne Paul Aime Noubissi Angèle Foyet Fondjo Idrice Kamtchouing Adela Ngwewondo Henri Wambe Joseph Ngakou Mukam Rene Kamgang Animal Physiology Laboratory Faculty of ScienceUniversity of YaoundéI237Cameroon Department of Biological Science Faculty of ScienceUniversity of Ngaoundéré237Cameroon Department of Zoology and Animal Physiology Faculty of ScienceUniversity of Buea237Cameroon Department of Applied Sciences for Health Higher Institute of Applied SciencesUniversity Institute of Gulf of Guinea237Cameroon Laboratory of Endocrinology and Radioisotopes Institute of Medical Research and Medicinal Plants Studies(IMPM)Yaoundé237Cameroon Department of Biological Science Faculty of ScienceUniversity of Dschang237Cameroon

Objective: Infectious diseases such as typhoid fever lead to the formation of free radicals which can damage the body. Many medicinal plants have antioxidant molecules that neutralize free radicals. The present work evaluated the antioxidant activity and histopathological effects of the dichloromethane fraction of Dichrocephala integrifolia in Salmonella typhi-infected ***: The S. typhi-infected rats concurrently received daily doses of D. integrifolia extract at doses of 25, 50 and 100 mg/kg body weight or ciprofloxacin(5 mg/kg body weight) for 15 days. Body temperature was measured daily during infection and treatment periods. At the end of treatment period, the animals were sacrificed and biological responses including hematological parameters, superoxide dismutase and catalase activities, and glutathione, malondialdehyde and nitric oxide concentrations were ***: The elevated body temperature induced by infection was significantly decreased in animals treated with 25, 50 or 100 mg/kg of the extract. Platelet levels decreased slightly in infected rats, while treatment with the dichloromethane fraction of D. integrifolia significantly increased platelet levels;this response was greater than that elicited by ciprofloxacin. The doses of 50 and 100 mg/kg of the dichloromethane fraction of D. integrifolia notably decreased monocyte and neutrophil values. Activity of superoxide dismutase and catalase and levels of glutathione in the tissues of treated animals were increased significantly(P < 0.01), while malondialdehyde and nitric oxide levels were significantly decreased(P < 0.01), following treatment with the dichloromethane fraction of D. ***: The results of this study show that the dichloromethane fraction of D. integrifolia has protective effects against a series of pathological conditions initiated by oxidation and tissue damage in the course of a S. typhi infection.

关键词： Typhoid fever Salmonella typhi Dichrocephala integrifolia Antioxidant stress Hematology

Low Birth Weight in Cameroon: Research and Analysis of Factors Associated with Their Occurrence in Douala Maternity Wards

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 758-778页

作者： Henri Essome merlin Boten Bounyom Astrid Ndolo Kondo Ingrid Doriane Ofakem Ilick Charlotte Epossè Ekoube Rita Bono Betoko Hassanatou Iyawa Fulbert Mangala Nkwele Théophile Nana Njamen Robert Tchounzou Alphonse Ngalame Nyong Charlotte Irène Cyrielle Edjoa Mboe Moustapha Bilkissou Junie Ngaha Yaneu Marga Vanina Ngono Akam Gervais Mounchikpou Ngouhouo Grâce Tocki Toutou Michel Roger Ekono Nelly Noubi Pascal Foumane Training Teaching and Research Unit in Gynecology Obstetrics and Reproduction Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Laquintinie Hospital Douala Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon Faculty of Health Sciences University of Buea Buea Cameroon Faculty of Medicine and Biomedical Sciences University of Yaound&#233 1 Yaound&#233 Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Ebolowa Ebolowa Cameroon

Introduction: Low birth weight (LBW) is defined by the World Health Organization (WHO) as a birth weight strictly below 2500 g, whatever the term of pregnancy. It constitutes a major public health problem, both in developed and developing countries, due to its magnitude and its strong association with infant morbidity and mortality. Main objective was to study the factors associated with the occurrence of small-for-gestational-age newborns in Douala. Methodology: We carried out a cross-sectional analytical study with prospective data collection using a technical pretested sheet in the maternity wards of the Douala General Hospital, the Laquintinie Hospital, and the District hospitals of Deido, Nylon and Bonassama over a period of 4 months (January to April 2020). We were interested in any newborn, born alive, vaginally or by cesarean section, of low weight, seen in the first 24 hours from a full-term single-fetal pregnancy whose mother had given her consent. Our sampling was consecutive and non-exhaustive. We excluded newborns whose term was unclear and those with congenital malformations or signs of embryo-foetopathy. Data collection was done using survey sheets. Statistical analyzes were carried out with CS Pro 7.3 and SPSS version 25.0 software. The Student, Chi-square and Fischer tests were used to compare the means of the variables, the percentages with a significance threshold P value Results: During the study period, 305 full-term newborns were included, divided into 172 boys and 133 girls. The percentage of small-for-gestational-age newborns was 9.8%;after multivariate analysis by logistic regression to eliminate confounding factors, we found maternal factors associated with small for gestational age newborns;maternal age less than 20 years, primiparity, gestational age (37 - 38), a delay in prenatal visits greater than 14 weeks, anemia in pregnancy, positive toxoplasmosis serology in pregnancy, a body mass index of Conclusion: Our study revealed the potenti

关键词： Newborn Low Birth Weight Gestational Age Douala

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烧结多载能气料面耦合喷吹装备系统

中国冶金 2024年第5期34卷 21-28页

作者：周浩宇叶恒棣魏进超刘前陈思墨李谦宋新义季志云中冶长天国际工程有限责任公司工程技术研究中心湖南长沙410205 中南大学资源加工与生物工程学院湖南长沙410083

富氢燃气喷吹强化烧结技术是一项可以节约烧结燃料、降低污染物排放、提高烧结矿产质量的先进技术,但是目前该技术在应用推广过程中遇到了无法与热风、烟气、蒸汽等载能气介质耦合作业的难题。通过数值仿真建模对传统装置结构开展流场分... 详细信息

富氢燃气喷吹强化烧结技术是一项可以节约烧结燃料、降低污染物排放、提高烧结矿产质量的先进技术,但是目前该技术在应用推广过程中遇到了无法与热风、烟气、蒸汽等载能气介质耦合作业的难题。通过数值仿真建模对传统装置结构开展流场分析,探明了导致多种载能气体无法耦合喷吹的根本原因是热风/烟气循环罩侧部的不均匀进风造成罩内流场紊乱;针对性研制了渐扩进气口、矩阵多孔式整流花板、稳流导流筒、反射叠喷管排等一系列核心部件,攻克了技术瓶颈,开发集成了烧结多载能气料面耦合喷吹装备系统。在国内某360 m~2烧结机生产现场投用后取得了良好效果,其台时产量提升了8 t/h,烧结工序能耗下降了2.5 kg/t,且富氢燃气的料面喷吹均匀度提升超过1倍,燃气罩内着火率降低90%,燃气顶部逃逸率降低95%,连续稳定运行周期明显延长。该项装备的研发拓宽了富氢燃气喷吹强化烧结技术的应用范围,推动了烧结工序的高效低碳化转型。

关键词：烧结富氢燃气多载能气耦合喷吹装备系统高效低碳