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Thrapeutic equivalence in the treatment of hypertension:Can lercanidipine and nifedipine GITS be considered to be interchangeable?

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World Journal of Cardiology 2014年第6期6卷 507-513页

作者： Henry L Elliott Peter A meredith Institute of Pharmaceutical and Biomedical Sciences University of StrathclydeGlasgow G4 0REUnited Kingdom Department of Medicine and Therapeutics University of GlasgowThe Western InfirmaryGlasgow G11 6NTUnited Kingdom

AIM: To undertake a review of the evidence that nifedipine GITS and lercanidipine are therapeutically equivalent in the management of essential ***: A systematic review of the published literature was prompted by the findings of two meta-analyses which indicated that there was a lower incidence of peripheral(ankle) oedema with lercanidipine. However,neither meta-analysis gave detailed attention to comparative antihypertensive efficacy or cardiovascular protection. Accordingly,a systematic,detailed and critical review was undertaken of individual published papers. The review started with those studies incorporated into the 2 meta-analyses and then all other salient and directly relevant papers identified through the following search criteria: all randomized controlled trials in which the therapeutic profile and antihypertensive effects of lercanidipine were directly compared with those of nifedipine GITS(in hypertensive patients). The searchstrategy was focused on the reports of clinical trials of lercanidipine vs nifedipine GITS,which were identified through a systematic search of PubMed(from 1966 to October 2012),Embase(from 1980 to October 2012) and the Cochrane library(from 1 October 2008 to end October 2013). The search combined terms related to lercanidipine vs nifedipine GITS(including MeSH search using calcium antagonists,calcium channel blockers and dihydropyridines).RESULTS: With regard to blood pressure(BP) control and the consistency of BP control throughout 24-h,there is limited published evidence. However,two studies using 24 h ambulatory blood pressure monitoring clearly identified the dose-dependency of BP lowering with lercanidipine and its variably sustained 24-h efficacy. In contrast,there is evidence of a consistent antihypertensive effect throughout 24 h with nifedipine GITS. The incidence of the most common "side effect",i.e.,peripheral(ankle) oedema can be estimated as follows. For every 100 patients treated with lercanidipine,

关键词： Nifedipine GITS Lercanidipine Therapeutic equivalence

A data directory to facilitate investigations on worldwide wildlife trafficking

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Big Earth Data 2023年第2期7卷 338-348页

作者： meredith L.Gore Rowan Hilend Jonathan OPrell Emily Griffin John R.Macdonald Burcu B.Keskin Aaron Ferber Bistra Dilkina Department of Geographical Sciences University of MarylandCollege ParkUSA Department of Supply Chain Management Michigan State UniversityEast LansingUSA Department of Information Sciences Statisticsand Management ScienceUniversity of AlabamaTuscaloosaUSA Operations and Information Management Division Babson CollegeWellesleyUSA Supply Chain Management Department of ManagementColorado State UniversityFort CollinsUSA Verterbi School of Engineering University of Southern CaliforniaLos AngelesUSA

Wildlife trafficking is a global phenomenon posing many negative impacts on socio-environmental *** exploration of wildlife trafficking trends and the impact of interventions is significantly encumbered by a suite of data reuse *** describe a novel,open-access data directory on wildlife trafficking and a corresponding visualization tool that can be used to identify data for multiple purposes,such as exploring wildlife trafficking hotspots and convergence points with other crime,discovering key drivers or deterrents of wildlife trafficking,and uncovering structural *** searches,expert elicitation,and peer-reviewed publications were used to search for extant sources used by industry and non-profit organizations,as well as those leveraged to publish academic research *** open-access data directory is designed to be a living document and searchable according to multiple *** directory can be instrumental in the data-driven analysis of unsustainable illegal wildlife trade,supply chain structure via link prediction models,the value of demand and supply reduction initiatives via multi-item knapsack problems,or trafficking behavior and transportation choices via network interdiction problems.

关键词： Illegal wildlife trade supply chain operations management interdiction conservation

The circadian clock contributes to diurnal patterns of plant indirect defense in nature

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Journal of Integrative Plant Biology 2019年第8期61卷 924-928页

作者： Youngsung Joo Jay K.Goldberg Lucille T.S.Chretien Sang-Gyu Kim Ian T.Baldwin meredith C.Schuman Department of Molecular Ecology Max Planck Institute for Chemical EcologyHans-Knoll-StraBe 8D-07745 JenaGermany Department of Biology Ecole Normale Superieure de Lyon(ENS L)46 Allee d'ltalie69007 LyonFrance Department of Biological Sciences Korea Advanced Institute of Science and TechnologyYuseong-guDaejeon 34141South Korea Department of Biology Indiana UniversityBloomingtonINUSA Institut de Recherche sur la Biologie de I'lnsecte(IRBI) UMR 7261CNRS/Universite Francois-Rabelais de ToursAvenue MongeParc Grandmont37200 ToursFrance Laboratory of Entomology(WUR) Wageningen University and Research CentreDroevendaalsesteeg 1Building 107/W0.Aa.0816708PB WageningenThe Netherlands Department of Geography University of ZurichWinterthurerstrasse 1908057 Zurich

The plant circadian clock regulates the rhythms of plant *** herbivore-induced plant volatiles(HIPVs)fluctuate,diurnally,but the role of the circadian clock in the emission of HIPVs and their ecological consequences remains largely ***,we show that the timing of herbivore attack can alter the outcome of tri-trophic interactions,and this is mediated by the circadian clock,under both field and glasshouse *** most HIPV emissions did not have a circadian rhythm,the circadian clock modulated HIPV emissions in a time-dependent *** mediate tri-trophic interactions,and the circadian clock may affect these interactions by modulating HIPV emission in nature.

关键词： herbivore glasshouse circadian rhythm

A Comparative Study of Translation Course Teaching Mode of English Teacher and Chinese Teacher from the Perspective of Interactive Teaching Theory

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疯狂英语（理论版） 2016年第3期 32-36页

作者：梁淑英 Grant David meredith 韶关学院外语学院广东韶关512000 澳大利亚联合大学计算机信息学院

The paper discusses a field study of different features of the teaching modes of English teacher and Chinese teacher from the perspective of interactive teaching *** survey of the translation course reform experimented in Chinese students classroom,the positive exposure of a foreign teacher combined with the work of a Chinese teacher's help in classroom are inspiring for further remolding of a better teaching mode tailored to some special group of Chinese students aiming for study abroad *** newly teaching mode developed above would serve as a reference for the teaching field.

关键词： translation course teaching mode interactive teaching theory

Designing a Citizen Science Project for Forest Landscapes: A Case from Hofmann Forest in Eastern North Carolina

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Open Journal of Forestry 2020年第2期10卷 187-203页

作者： meredith Hovis Frederick Cubbage Diana Rashash North Carolina State University Raleigh NC USA North Carolina Cooperative Extension Service Jacksonville NC USA

Citizen science is a participatory research design that utilizes both non-professional researchers and professional researchers to collect, analyze, and disperse data. Citizen scientists seek to discover answers and draw solutions to scientific questions. The Hofmann Open Water Laboratory (HOWL) project, established in 2016, focuses its collaborative-based efforts in eastern North Carolina. HOWL citizen scientists monitor water quality, and quantity, that flows on and off the Hofmann Forest. HOWL provides opportunities to citizen scientists and gathers data to meet the project outcomes, which include understanding the importance of Hofmann Forest in the inner coastal plain of North Carolina, building science education skills for citizen science participants, and enhancing community relationships between the forest and citizens. This article outlines several approaches for developing citizen science projects in a forest context, drawing on experiences from HOWL. The paradigm can be used to meet the needs of any forest landscape’s research and management goals, while employing a participatory research approach. The guidelines present suggestions for productive and enduring processes for citizen engagement and project sustainability. Each project will need participants to set goals, build a diverse collaboration, and establish on-going evaluation processes to determine successful and failed components that ensures the project moves forward effectively. The citizen science efforts near the Hofmann Forest in Eastern North Carolina provided an excellent case study of the development of citizen science on the forest and adjacent lands. HOWL attempts to meet participant and socio-ecological outcomes, such as encouraging public action in natural resource and forest management, as well as enhancing scientific knowledge and skills. The project helps synthesize our experiences in this effort and the social science literature, providing reasonable guidelines for those seeking to

关键词： Citizen Science Forest Landscapes Forest Context Public Participation Project Design

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Push-button English

大学英语 1985年第5期 33-34页

作者： John meredith-Parry 赵琏

Very soon a computer will be able to teach you English. It will also be able to translate any language for you too. It’s just one more incredible result of the development of microprocessors-those tiny parts of a computer commonly known as‘silicon chips’. So give up going to classes, stop buying more textbooks and relax. In a couple of years you won’t need the international language of English.

关键词：英国广播公司 Push-button English BBC

“孔雀西北飞，五里一徘徊”--罗红玫在纽约

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舞蹈 2009年第4期 52-55页

作者：陈帼 Aeric meredith-Goujon

元旦前，Aly Rose（中文名罗红玫）Email给我说纽约大学有一个题名为“重新发现中国文化大革命”的周末学术讨论会，问我要不要参加，我去了。为期三天的讨论会由不同的专家学者的专题发言和现场讨论组成。AlyRose以她的严谨、真诚和幽... 详细信息

元旦前，Aly Rose（中文名罗红玫）Email给我说纽约大学有一个题名为“重新发现中国文化大革命”的周末学术讨论会，问我要不要参加，我去了。为期三天的讨论会由不同的专家学者的专题发言和现场讨论组成。AlyRose以她的严谨、真诚和幽默，从艺术、政治以及艺术家、老百姓的不同角度讲述了样板戏的文化现象和它在中国的影响。不夸张、不矫情，发自一个舞蹈内行的见地，不温不火地阐述了一段属于历史的表演艺术的形式与内容，连《在延安文艺座谈会上的讲话》都讲解得一清二楚。

关键词：纽约大学《在延安文艺座谈会上的讲话》学术讨论会西北孔雀文化大革命形式与内容 Rose

Assessing vulnerability to panic:a systematic review of psychological and physiological responses to biological challenges as prospective predictors of panic attacks and panic disorder

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General Psychiatry 2019年第6期32卷 297-303页

作者： Donald J Robinaugh meredith J Ward Emma R Toner Mackenzie L Brown Olivia M Losiewicz Eric Bui Scott P Orr Department of Psychiatry Massachusetts General HospitalBostonMassachusettsUSA Department of Psychiatry Harvard Medical SchoolBostonMassachusettsUSA

Background Cognitive-behavioural theories of panic disorder posit that panic attacks arise from a positive feedback loop between arousal-related bodily sensations and perceived *** a recently develope computational model formalising these theories of pani attacks,it was observed that the response to a simulate perturbation to arousal provided a strong indicator of vulnerability to panic attacks and panic *** this/review,we evaluate whether this observation is borne o in the empirical literature that has examined responses biological challenge(eg,C02 inhalation)and their relatio to subsequent panic attacks and panic *** We searched PubMed,Web of Science and PsycINFO using keywords denoting provocation agents(eg,sodium lactate)and procedures(eg,infusion)combined with keywords relevant to panic disorder(eg,panic).Articles were eligible if they used response to a biologic challenge paradigm to prospectively predict panic attac or panic *** We identified four eligible *** effect sizes suggest that there is biological challenge response a moderate prospective association with subsequent pani attacks,but no prospective relationship with panic disorde Conclusions These findings provide support for the prediction derived from cognitive-behavioural theories an some preliminary evidence that response to a biological challenge may have clinical utility as a marker of vulnerab to panic attacks pending further research and developme Trial registration number 135908.

关键词： behaviour subsequent sizes

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Family Rain Day

小学生时代（大嘴英语） 2021年第1期 24-27页

作者： Suzy Levinson meredith Crandall Brown(图) 不详

Baking cookies,Pillow forts,Silly dancing,Books(all sorts),Jigsaw puzzles,Model planes…We're so happyWhen it rains!

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