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君丰大曲酱香白酒出池酒醅特性与各轮次基酒风味相关性分析

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中国酿造 2022年第7期41卷 64-70页

作者：余硕文佘荣书韩兴林张娇娇胡景辉何猛超蒙德俊王德良新疆农业大学食品科学与药学学院新疆乌鲁木齐830052 中国食品发酵工业研究院有限公司北京100015 贵州酣客君丰酒业有限公司贵州仁怀564501 百色学院农业与食品工程学院广西百色533000

对君丰大曲酱香白酒酿造过程出池酒醅的理化指标进行分析,采用高通量测序技术解析酒醅中微生物菌群变化规律,利用气质联用(GC-MS)分析轮次酒的风味物质构成,并阐释酒醅特性与风味物质的相关性。结果表明,在白酒酿造过程中,出池酒醅水分... 详细信息

对君丰大曲酱香白酒酿造过程出池酒醅的理化指标进行分析,采用高通量测序技术解析酒醅中微生物菌群变化规律,利用气质联用(GC-MS)分析轮次酒的风味物质构成,并阐释酒醅特性与风味物质的相关性。结果表明,在白酒酿造过程中,出池酒醅水分含量、酸度、还原糖含量均呈现先增加后降低,至5~6轮次略有回升的趋势,淀粉含量呈现不断降低的趋势。酒醅中共检测出71种细菌属和43种真菌属,优势细菌属为乳酸杆菌属(Lactobacillus)、unidentified Mitochondria等,优势真菌属为伊萨酵母属(Issatchenkia)、毕赤酵母属(Pichia)、酵母属(Saccharomyces)等。相关性分析结果表明,毕赤酵母属(Pichia)、醋酸杆菌属(Acetobacter)等受淀粉和还原糖影响比较大,接合酵母属(Zygosaccharomyces)、明梭孢属(Monographella)和海洋芽孢杆菌(Oceanobacillus)等受水分和酸度影响比较大,与风味物质相关性较强的微生物有假单胞菌属(Psedomonas)、片球菌属(Pediococcuspichia)、接合酵母属(Zygosaccharomyces)和假丝酵母属(Candida)等。

关键词：酱香型白酒理化指标风味化合物微生物菌群相关性分析

基于多元色谱和主成分分析解析酱香型白酒大回酒风味品质研究

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中国酿造 2021年第11期40卷 161-168页

作者：张娇娇郭松波余硕文苏建如胡景辉薛新新何猛超韩兴林中国食品发酵工业研究院有限公司北京100015 天津科技大学生物工程学院天津300457 贵州钓鱼台国宾酒业有限公司贵州仁怀564501 新疆农业大学食品科学与药学学院新疆乌鲁木齐830052 贵州民族大学生态环境工程学院贵州贵阳550025

该研究采用气相色谱、离子色谱等分析方法解析酱香型白酒轮次基酒风味物质,结合主成分分析(PCA),剖析酱香型白酒大回酒风味构成特征,同时初步分析贮存时间对酱香型白酒风味品质的影响。结果显示,大回酒品质较好是由于其酯类、酸类物质... 详细信息

该研究采用气相色谱、离子色谱等分析方法解析酱香型白酒轮次基酒风味物质,结合主成分分析(PCA),剖析酱香型白酒大回酒风味构成特征,同时初步分析贮存时间对酱香型白酒风味品质的影响。结果显示,大回酒品质较好是由于其酯类、酸类物质占比高,分别为38%~50%、29%~36%,而醇类物质含量占比较少为10%~19%,其中乳酸乙酯、乳酸和3-羟基-2-丁酮等成分含量相对较高,高级醇类物质含量相对较低,多元醇含量适中。通过分析贮存时间对大回酒风味的影响发现,随着贮存时间的延长,风味物质总量有所降低,且出现“酯减”的变化趋势,其中醛类物质变化较为明显,乙醛和乙缩醛呈现增加趋势,而糠醛呈现降低趋势。此外,主成分分析显示乳酸和乳酸乙酯对酱香型白酒大回酒基酒品质具有较强的正相关性。

关键词：酱香型白酒大回酒多元色谱主成分分析风味

Risk Factors of Early Complications after Pancreaticoduodenectomy in 200 Consecutive Patients

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The Chinese-German Journal of Clinical Oncology 2005年第4期4卷 194-198页

作者：程庆保张宝华罗祥基张永杰姜小清易滨俞文隆吴孟超张柏和上海第二军医大学附属东方肝胆外科医院胆道外科 200438

To study the risk factors for early complications after pancreaticoduodenectomy （PD）. Methods： Two hundred patients undergoing PD at our hospital between December 1996 and September 2002 were reviewed retrospectively. Standard PD was performed on 176 cases, standard PD with extended lymphadenectomy on 24 patients, whereas pylorus-preserving PD was not used. An end-toside combined with mucosa-to-mucosa pancreaticojejunostomy was performed on the patients with a hard pancreas and a dilated pancreatic duct, and a traditional end-to-end invagination pancreaticojejunostomy on the patients with a soft pancreas and a non-dilated duct. The risk factors with the potential to affect the incidence of complications were analyzed with SAS 8.12 software. Logistic regression was then used to determine the effect of multiple factors on early complications. Results： The overall rate of the major com- plications was 21% （42/200）, with the failure of pancreaticojejunal anastomosis being the most frequently encountered. Age （odds ratio [OR] 2.162）, diabetes mellitus （OR 4.086）, total serum bilirubin level （OR 7.556）, end-to-end pancreaticojejunostomy （OR 2.616）, T tube through the choledochojejunostomy （OR 0.100）, and blood transfusion over 1000 mL （OR 2.410） were the significant risk factors for the morbidity. Conclusion： The results from published series concerning morbidity after pancreaticoduodenectomy are not comparable because of lack of homogeneity between them. The knowledge of the complications rate in each particular department turns out essentially to provide the patient with tailored information about risks before surgery. Additionally, management of postoperative complications is essential for improving the results of this operation.

关键词： pancreaticoduodenectomy surgical complications pancreatic fistula

Serum ceruloplasmin can predict liver fibrosis in hepatitis B virusinfected patients

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World Journal of Gastroenterology 2020年第27期26卷 3952-3962页

作者： Na-Ling Kang Jie-Min Zhang Meng-Xin Lin Xu-Dong Chen Zu-Xiong Huang yue-Yong Zhu yu-Rui Liu Da-Wu Zeng Liver Center The First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Pharmacy The First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Infectious Diseases The First Hospital of Quanzhou Affiliated with Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Gastroenterology the 910th Hospital of the People's Liberation ArmyQuanzhou 362000Fujian ProvinceChina Hepatology Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhou 350005Fujian ProvinceChina

BACKGROUND The presence of significant liver fibrosis in hepatitis B virus(HBV)-infected individuals with persistently normal serum alanine aminotransferase(PNALT)levels is a strong indicator for initiating antiviral *** ceruloplasmin(CP)is negatively correlated with liver fibrosis in HBV-infected *** To examine the potential value of serum CP and develop a noninvasive index including CP to assess significant fibrosis among HBV-infected individuals with *** Two hundred and seventy-five HBV-infected individuals with PNALT were retrospectively *** association between CP and fibrotic stages was statistically analyzed.A predictive index including CP[Ceruloplasmin hepatitis B virus(CPHBV)]was constructed to predict significant fibrosis and compared to previously reported *** Serum CP had an inverse correlation with liver fibrosis(r=-0.600).Using CP,the areas under the curves(AUCs)to predict significant fibrosis,advanced fibrosis,and cirrhosis were 0.774,0.812,and 0.853,*** CPHBV model was developed using CP,platelets(PLT),and HBsAg levels to predict significant *** AUCs of this model to predict significant fibrosis,advanced fibrosis,and cirrhosis were 0.842,0.920,and 0.904,*** was superior to previous models like the aspartate aminotransferase(AST)-to-PLT ratio index,Fibrosis-4 score,gamma-glutamyl transpeptidase-to-PLT ratio,Forn’s score,and S-index in predicting significant fibrosis in HBV-infected individuals with *** CPHBV could accurately predict liver fibrosis in HBV-infected individuals with ***,CPHBV can be a valuable tool for antiviral treatment decisions.

关键词： Ceruloplasmin Liver fibrosis Chronic hepatitis B infection Serum alanine aminotransferase Noninvasive model Receiver-operating characteristic

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模块化多电平逆变器仿真研究

电气化铁道 2024年第5期35卷 87-92页

作者：葛孟超黄守权白青林缑向阳于培培李保宗中铁电气工业有限公司北京市轨道交通运营管理有限公司

模块化多电平逆变器具有输出谐波含量低、扩展性强、控制灵活等优势,在高压大功率场合得到广泛应用。本文通过深入分析模块化多电平逆变器的拓扑结构、数学模型和工作原理,基于PI控制策略设计功率电流双闭环控制器;为减小桥臂电流畸变... 详细信息

模块化多电平逆变器具有输出谐波含量低、扩展性强、控制灵活等优势,在高压大功率场合得到广泛应用。本文通过深入分析模块化多电平逆变器的拓扑结构、数学模型和工作原理,基于PI控制策略设计功率电流双闭环控制器;为减小桥臂电流畸变、改善内部环流,基于比例谐振控制策略设计环流抑制器;为减小子模块电压波动,采用电容电压冒泡排序法和最近电平调制策略。利用MATLAB软件搭建了系统的仿真模型,并在额定运行和功率阶跃的工况下进行仿真验证,测试结果表明控制算法能快速跟随目标值,有效抑制桥臂电流二倍频分量,电容电压均衡,并验证了所建模型的正确性。

关键词：模块化多电平逆变器 PI控制比例谐振控制环流抑制最近电平调制

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峨眉金线兰的生药鉴别

生物资源 2023年第6期45卷 584-591页

作者：韩玉王硕硕彭梦超陈慧玲郑承剑吴岩斌吴锦忠福建中医药大学药学院福建福州350122 海军军医大学药学院上海200433

金线兰属植物形态相似,峨眉金线兰(Anoectochilus emeiensis)为金线兰(Anoectochilus roxburghii)的近缘种。调查发现,市场上常将峨眉金线兰当作金线兰使用,为区分两者,本试验采用生药学鉴定方法观察峨眉金线兰的原植物形态、组织构造... 详细信息

金线兰属植物形态相似,峨眉金线兰(Anoectochilus emeiensis)为金线兰(Anoectochilus roxburghii)的近缘种。调查发现,市场上常将峨眉金线兰当作金线兰使用,为区分两者,本试验采用生药学鉴定方法观察峨眉金线兰的原植物形态、组织构造及粉末显微特征;采用HPLC⁃ELSD法测定峨眉金线兰中主要内酯苷的含量。峨眉金线兰叶片为卵形,具有金红色网纹;花不倒置,唇瓣白色,前部裂片长圆状倒披针形,中部两侧各具1枚宽大长圆形的褶片且其边缘具疏锯齿。显微结构中,根茎横切面中皮层宽广,根木质部导管2~5个成束,茎木质部导管1~8个成束;叶横截面叶肉细胞中有大量红色物质,上表皮呈乳突状突起,下表皮气孔较多,气孔以不定式为主;粉末中可见草酸钙针晶和导管。3批峨眉金线兰中金线莲苷和斑叶兰苷(goodyeroside A)的含量分别为32.66~35.21 mg/g和134.41~137.72 mg/g,分别在100~500μg/mL和200~1000μg/mL质量浓度范围内呈良好的线性关系,平均加样回收率分别为100.51%(RSD=1.56%)和97.50%(RSD=1.54%)。以上特征可为峨眉金线兰的生药鉴别提供参考依据。

关键词：峨眉金线兰生药鉴别高效液相蒸发散射法含量测定

Sleep fragmentation as an important clinical characteristic of sleep disorders in Parkinson's disease: a preliminary study

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Chinese Medical Journal 2019年第15期132卷 1788-1795页

作者： Guo-En Cai Shan Luo Li-Na Chen Jian-Ping Lu yu-Jie Huang Qin-Yong Ye Department of Neurology Fujian Medical University Union Hospital Fuzhou Fujian 350001 China Department of Radiology Longyan First Hospital Affiliated to Fujian Medical University Longyan Fujian 364000 China Department of Ultrasound Mengchao Hepatobiliary Hospital of Fujian Medical University Fuzhou Fujian 350025 China

Background:Sleep disorders are one of the earliest non-motor symptoms of Parkinson's disease (PD).Sleep disorders could,therefore,have value for recognition and diagnosis in ***,no unified classification and diagnostic criteria exist to evaluate sleep disorders by polysomnography (PSG).Utilizing PSG to monitor sleep processes of patients with PD and analyze sleep disorder characteristics and their relationship with demographic parameters could aid in bridging this *** preliminary study aimed to evaluate the clinical characteristic of sleep disorders in PD using ***:PSG was used to evaluate sleep disorders in 27 patients with PD and 20 healthy volunteers between August 2015 and July 2018 in Fujian Medical University Union *** sleep time (TST),sleep efficiency (SE),total wake time,and other parameters were compared between the two ***,the correlation between sleep disorders and age,disease duration,Unified Parkinson's Disease Rating Scale-Ⅲ scores,Hoehn-Yahr stage,and levodopa dose were *** main statistical methods included Chi-square test,two independent samples t test,Fisher exact test,and Pearson ***:Sleep fragmentation in the PD group was significantly increased (74.1%) while difficulty falling asleep and early awakening were not,as compared to healthy *** significant differences were found in time in bed,sleep latency (SL),non-rapid eye movement (NREM) stage 1 (N1),N1%,N2,N2%,N3%,and NREM% between PD and control groups;but TST (327.96± 105.26 min vs.414.67 ± 78.31 min,P =0.003),SE (63.26%± 14.83% vs.76.8%± 11.57%,P =0.001),R N3 (20.00 [39.00] min vs.61.50 [48.87] min,P=0.001),NREM (262.59 ± 91.20 min vs.337.17± 63.47 min,P=0.003),rapid-eyemovement (REM)(32.50 [33.00] min vs.85.25 [32.12] min,P < 0.001),REM%(9.56 ± 6.01 vs.15.50 ± 4.81,P =0.001),REM sleep latency (157.89 ± 99.04 min vs.103.47 ± 71.70 min,P =0.034) were significantly reduced in PD ***:This preliminary study supp

关键词： Parkinson's disease Sleep fragmentation Polysomnography Clinical characteristic

2022—2023年哈尔滨市蜱叮咬就诊人群森林脑炎、阿龙山病毒感染状况

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中华疾病控制杂志 2024年第11期28卷 1349-1354页

作者：路雅贤王伟张露彭晓红陈登辉张宇周梦超田行李婉婷吕首旭吴文忠侯志军黑龙江省森工总医院蜱媒疫病研究中心哈尔滨150040 东北林业大学野生动物与自然保护地学院虫媒疫病与病原生态学实验室哈尔滨150040

目的探究2022—2023年在黑龙江省森工总医院就诊的哈尔滨市蜱叮咬人群中森林脑炎(tick-borne encephalitis virus,TBEV)、阿龙山病毒(Alongshan virus,ALSV)的感染情况。方法利用2022—2023年在黑龙江省森工总医院就诊的哈尔滨市蜱叮咬... 详细信息

目的探究2022—2023年在黑龙江省森工总医院就诊的哈尔滨市蜱叮咬人群中森林脑炎(tick-borne encephalitis virus,TBEV)、阿龙山病毒(Alongshan virus,ALSV)的感染情况。方法利用2022—2023年在黑龙江省森工总医院就诊的哈尔滨市蜱叮咬人群的检测数据,通过流行病学调查和系统发育树构建,探究森林脑炎和阿龙山热的感染情况。结果2022—2023年在黑龙江省森工总医院就诊的哈尔滨市蜱叮咬的人数为159人,其中阿城区和宾县分别占该院总哈尔滨市蜱叮咬就诊人群的30.19%(48/159)和16.35%(26/159);哈尔滨市的主城区为松北区、道外区、道里区、南岗区、香坊区,分别有7、1、3、7、7名人员被蜱叮咬后到黑龙江省森工总医院就诊。在该院哈尔滨市蜱叮咬就诊人群中,森林脑炎和阿龙山热病毒的感染率分别为37.74%(60/159)和10.06%(16/159)。在该院就诊的哈尔滨市蜱叮咬的人群中检出的TBEV为远东亚型。结论在哈尔滨市的市区和周边县(市)均有被蜱叮咬的风险,并可能感染TBEV和ALSV;除森林脑炎和阿龙山热外,哈尔滨市还可能流行莱姆病、斑点热等其他蜱媒疫病,应加强哈尔滨市蜱传疾病流行情况的监测,广泛宣传预防蜱媒疫病的知识。

关键词：蜱媒疫病森林脑炎病毒阿龙山病毒发热

近5届奥运会中国游泳队奖牌分布及成绩特征分析

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体育科技文献通报 2022年第5期30卷 17-20页

作者：孙秀洁于杰赵鲁南吴奕君杨铄史碧莹刘鑫姜孟超赵淑君曲阜师范大学体育科学学院山东曲阜273165 曲阜师范大学公共外语教学部山东曲阜273165 宁波大学体育学院浙江宁波315211

运用文献资料法、对比分析法、逻辑分析法等研究方法,对近5届夏季奥运会我国游泳队的成绩进行统计分析可知:(1)世界竞技游泳项目呈现出“以美国为主,澳大利亚为辅,其余国家上下波动”的现象,我国游泳项目总成绩位于第3位,共获得30枚奖牌... 详细信息

运用文献资料法、对比分析法、逻辑分析法等研究方法,对近5届夏季奥运会我国游泳队的成绩进行统计分析可知:(1)世界竞技游泳项目呈现出“以美国为主,澳大利亚为辅,其余国家上下波动”的现象,我国游泳项目总成绩位于第3位,共获得30枚奖牌,其竞技实力稍有提升,但与美国、澳大利亚相比,仍存在差距。(2)从运动员身体形态看,我国运动员的身高呈现“高大化”的特征,BMI指数较好;从年龄特征看,我国女子游泳运动员的优势年龄是18、19和23岁,男子运动员在25岁左右易发挥最好成绩;从金牌统治力上来看,女运动员明显高于男运动员。(3)我国男子游泳队有6个项目获得过奖牌,女子游泳队有11个项目获得过奖牌,男子在400米自由泳项目上表现突出,女子在200米蝶泳项目上表现优异。(4)从整体上看,我国游泳队的竞技能力、综合实力发挥很不稳定,需要进一步巩固加强。

关键词：奥运会中国游泳队成绩特征

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