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Chinese Chemical Letters 2014年第9期25卷 1275-1278页

作者： An-Qi Ju meng-juan li Miao Luo Ming-Qiao Ge Key Laboratory of Eco-textiles Ministry of EducationJiangnan University College of Textile & Clothing Jiangnan University School of Pharmacy East China University of Science and Technology

In order to improve the stabilization and spinnability of polyacrylonitrile, a bifunctional comonomer containing both ester and amide groups was synthesized to prepare poly（acrylonitrile-co-3- aminocarbonyl-3-butenoic acid methyl ester） [P（AN-co-ABM）] copolymers used as the carbon fiber precursor instead of poly（acrylonitrile-acrylamide-methyl acrylate） [P（AN-AM-MA）] terpolymer. The differential scanning calorimetry and thermogravimetry results show that the stabilization of P（AN-co- ABM） have been remarkably improved by ABM compared with P（AN-AM-MA） terpolymer, such as lower initiation temperature, broadened exothermic peak and smaller activation energy. Moreover, the spinnability of P（AN-co-ABM） is also improved by ABM due to the lubrication of ester groups in ABM. This study clearly shows that P（AN-co-ABM） copolymer is a better material for use as a carbon fiber precursor than P（AN-AM-MA） terpolymer.

关键词： Polymerization Stabilization DSC Spinnability Carbon fiber

In situ polymerization of aniline in electrospun microfibers

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Chinese Chemical Letters 2014年第1期25卷 83-86页

作者： Xiao-Qiang li Wan-Wan liu Shui-Ping liu meng-juan li Yong-Gui li Ming-Qiao Ge Key Laboratory of Eco-textiles Ministry of EducationJiangnan University College of Textile & Clothing Jiangnan University

Conductive microfibers with an average diameter of ca. 1.0 μm were prepared by in situ polymerization of aniline, in which poly（vinylchloride-acrylonitrile）（PVC-AN） was used as the filament-material in electrospinning to form precursor microfibers and carry the aniline monomers. Fourier-transform infrared （FTIR） results demonstrated that PANi was successfully polymerized in the microfibers. The morphology of the PVC-AN-PANi microfibers was observed by scanning electron microscopy （SEM）. Results of differential scanning calorimetry indicated that the polymer composite of PVC-AN-PANi formed via molecular interactions. Although the conductivity of PVC-AN-PANi microfibers was still limited （2.2 × 10^-8 S/cm）, this method provided an effective and convenient approach for preparing highly uniform and soft microfibrous electrodes.

关键词： Conductive microfibers Electrospinning Polymer composite Polyaniline

Preparation,characterization and biocompatibility of aspartic acid modified CdTe quantum dots

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Chinese Chemical Letters 2014年第6期25卷 933-936页

作者： Shui-Ping liu Jia-Jia Fu meng-juan li lin lin Xiao-Qiang li Ming-Qiao Ge Key Laboratory of Eco-Textiles Ministry of Education(Jiangnan University) College of Textile & Clothing Jiangnan University School of Food & Biological Engineering Jiangsu University Technical University of Denmark DTU FoodSoltofts Plads B227.2800 Kgs.LyngbyDenmark

This study aims at preparing water soluble aspartic acid （ASP） modified CdTe quantum dots with tunable fluorescence emission controlled by reaction time. The size of the synthesized CdTe quantum dots was evaluated using transmission electron microscope （TEM） and also calculated based on their UV-vis spectra. The optical properties of TGA-CdTe quantum dots were characterized by UV-vis and fluorescence （FL） spectroscopy. The red-shift in the UV-vis absorption and FL emission with the increase of reaction time was observed. The biocompatibility examination indicated that the ASP modified CdTe QDs had low cytotoxicity.

关键词： Water-soluble quantum dots CdTe Surface modification Biocompatibility

Synthesis, Resolution, and Enantiomeric Purity Assay of 2-n-Butylbutanedioic Acid 4-t-Butyl Esters

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Chemical Research in Chinese Universities 2006年第5期22卷 584-588页

作者： ZHANG Da-tong TANG li-da DUAN Gui-yun ZHAO Gui-long XU Wei-ren meng li-juan WANG Jian-wu School of Chemistry and Chemical Engineering Shandong University Jinan 250100 P. R. China The Pharmaceutical Research Institute of Tianjin Tianjin 300193 P. R. China

Racemic 2-n-butylbutanedioic acid 4-t-butyl esters were synthesized from methyl hexanoate and t-butyl α-iodoacetate via alkylation and subsequently selective hydrolyzation. The （R）-and （S）-2-n-butylbutanedioic acid 4-t-butyl esters were obtained by the resolution of the above-mentioned racemic compounds with（S）-（ - ） or（R）-（＋）-α- methylbenzylamine, respectively. The e.e. values of the two optical active products were determined to be above 99% by HPLC after the formation of two pairs of diastereoisomers with（R）-（＋）-α-methylbenzylamine and（S）- phenylalanine methyl ester.

关键词： Methyl hexanoate 4-t-Butyl 2-n-butylbutanedioic acid Resolution e.e. Value

Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging

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Science China Chemistry 2025年第1期68卷 26-34页

作者： Yutao Zhang juan li Wei-Hong Zhu Zhiqian Guo Shanghai Key Laboratory of Functional Materials Chemistry Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology State Key Laboratory of Bioreactor Engineering Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell MetabolismEast China University of Science & Technology

Sequence-activated chemiluminescence(CL) technique offers a unique approach to detecting specific biomolecules or cellular events with high sensitivity and spatial resolution. The fundamental principle behind sequence-activated CL probes involves tailoring highly-controllable CL signals in response to specific sequences or events of interest, thus enabling high-contrast signals under complex physiological conditions. This sequential activation could be triggered by enzymes, reactive oxygen species(ROS), biothiols or changes in the microenvironment. These unique sequence-activated CL probes bestow several advantages, including minimal background, deep-tissue penetration, and the ability of non-invasive or minimally invasive detection. The sequence-activated CL techniques represent a significant advancement in molecular imaging and diagnostics. In this mini-review, we focus on the latest developments in sequential CL probes, addressing the technical challenges and discussing the future trajectory by harnessing CL signaling and molecular recognition.

关键词： chemiluminescnece sequence-activation in-vivo bioimaging cyclic peroxide

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我国农产品营销渠道优化:日本经验与启示

价格月刊 2016年第2期 85-89页

作者：孟莉娟河南财政税务高等专科学校河南郑州451464

为适应农业现代化和农产品国际化竞争局面,日本根据本国农产品生产规模、标准化和科技化程度,逐步形成了独具特色的农产品营销渠道模式。"它山之石,可以攻玉",在对日本农产品营销渠道实践经验进行总结的基础上,结合我国农产品营销渠道... 详细信息

为适应农业现代化和农产品国际化竞争局面,日本根据本国农产品生产规模、标准化和科技化程度,逐步形成了独具特色的农产品营销渠道模式。"它山之石,可以攻玉",在对日本农产品营销渠道实践经验进行总结的基础上,结合我国农产品营销渠道现状及存在的问题,提出了我国农产品营销渠道模式优化的对策建议。

关键词：农产品营销渠道模式优化日本经验借鉴

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan Jiao lingyan meng Kang Du Xuezhi li School of Mental Health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

回到“原点”——高职商务英语专业人才培养模式初探

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教育学术月刊 2009年第1期 107-109页

作者：孟丽娟辽宁渤海大学高职学院

在市场需求的强势指引下,我国许多高校相继设置了商务英语专业,学历层次上呈现出一种多样化态势,高职商务英语的设置也正是迎合了这一社会需求。那么,如何根据高职的特色设置商务英语专业人才的培养模式便凸显在我们的面前。本文试从回... 详细信息

在市场需求的强势指引下,我国许多高校相继设置了商务英语专业,学历层次上呈现出一种多样化态势,高职商务英语的设置也正是迎合了这一社会需求。那么,如何根据高职的特色设置商务英语专业人才的培养模式便凸显在我们的面前。本文试从回到"原点",重新缕析了商务英语专业的学科定位及高职商务英语专业的培养目标,并从宏观与微观两个方面探讨了高职商务英语专业人才的培养模式。

关键词：商务英语高职商务英语专业人才培养模式

Dual contour edge information fusion for 3D aircraft skin circular hole detection

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Optoelectronics Letters 2025年第2期21卷 105-112页

作者： liU Hongjun ZHANG Naiwen meng Fanxi li Boyuan School of Mechanical and Electrical Engineering Shenyang University of Aeronautics and Astronautics

To address the challenges of varied aircraft skin hole detection types and susceptibility to noise,this paper proposes a method based on the perspective of dual contour edge information *** core method combines stereoscopic vision and structured light dual contour information consistently,focusing on extracting edge point information around the hole edge to achieve precise detection of circular *** this approach,a line multi-directional gradient feature detector (LMGFD) is introduced for locating the holes from plane stereoscopic ***,we establish a three-dimensional (3D) circular hole detection method (BPCircle) based on the dual contour edge information ***,experiments demonstrate that our proposed method achieves superior accuracy and robustness based on public benchmark dataset and our own collected standard IPCDS dataset (including two-dimensional (2D)images,3D point clouds,and measured data of three-coordinate measuring machine).The dataset and code can be found from https://***/Nicholsdqw/123.

关键词： Stereo image processing

国外引进红三叶种质在甘肃中部地区的生长特性及生产性能初步评价

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草业学报 2015年第9期24卷 30-42页

作者：孟丽娟赵桂琴甘肃农业大学草业学院草业生态系统教育部重点实验室中-美草地畜牧业可持续发展研究中心

为丰富我国红三叶种质资源,给红三叶品种选育提供优异材料,探讨国外引进资源在甘肃中部地区的综合表现,本文以来自俄罗斯、加拿大和美国的31份红三叶种质为供试材料,对其形态特征、农艺性状、生产性能等方面的14个指标进行了测定,发现... 详细信息

为丰富我国红三叶种质资源,给红三叶品种选育提供优异材料,探讨国外引进资源在甘肃中部地区的综合表现,本文以来自俄罗斯、加拿大和美国的31份红三叶种质为供试材料,对其形态特征、农艺性状、生产性能等方面的14个指标进行了测定,发现其在生育期、株高、分枝数、叶面积、茎叶比、再生速度和干草产量等指标上差异非常显著。来源地对供试材料的形态特征和生产性能也有影响。个别种质材料在单一性状上表现优异,可直接应用于生产。通过主成分分析,选取方差累计贡献率达78.94%的前5个主成分对供试材料进行综合评价,结果表明,31份种质中,来自俄罗斯的ZXY2008P-4996综合得分最高,表现最优,其次是来自美国的Scarlett和Star fireⅡ;ZXY2008P-5419综合得分最低,适应性最差。依据主成分向量可将31份红三叶种质聚为4类。

关键词：红三叶种质资源主成分分析聚类分析适应性评价