检索结果-南通市图书馆

Toxic keratopathy associated with abuse of topical anesthetics and amniotic membrane transplantation for treatment

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第5期8卷 938-944页

作者： Ozlem Yalcin Tok Levent Tok Inci meltem Atay Tugba cakmak Argun Nazire Demirci Alime Gunes Department of Ophthalmology Süleyman Demirel University Research and Education Hospital Department of Psychiatry Süleyman Demirel University Research and Education Hospital

AIMTo evaluate the clinical findings of toxic keratopathy associated with abuse of topical anesthetics and the treatment efficacy of amniotic membrane transplantation (AMT).METHODSFifteen eyes of 10 patients with abuse of topical anesthetics were included in this study. The data collected included patients' demographic information, initial best corrected visual acuity (BCVA), clinical findings, time to AMT, duration of epithelization, additional treatments, posttreatment BCVA, and the results of psychiatric *** patients were male, with the mean age of 37.9±5.4y. The patients had received 0.5% proparacaine hydrochloride due to pain resulting from foreign bodies, such as welding flash burns and car battery explosions, for a mean of 18.2±12.4d. The mean initial BCVA of the patients was 0.069±0.100. All patients had persistent epithelial defects, stromal infiltration, ring ulcer, and corneal edema. Initially, medical treatment was attempted in all cases. Because of severe pain, persistent epithelial defects and progressing stromal thinning did not improve with medical treatment, thus, the patients underwent AMT. The mean posttreatment BCVA of the patients was 0.33±0.27. All of them, except for two patients, showed improved visual acuity. One patient underwent evisceration for corneal melting and endophthalmitis in another center, and one patient underwent evisceration for severe pain of unknown origin. All 5 patients who consented to a psychiatric examination had depression, had personality disorder, and used *** appears to be an effective method for pain relief, rapid epithelial and stromal healing; however, visual prognosis is still poor despite medical and surgical interventions.

关键词： amniotic membrane transplantation ring stromal infiltration topical anesthetic abuse toxic keratopathy

The fatty acid compositions of predator Piocoris luridus （Heteroptera： Lygaeidae） and its host Monosteria unicostata （Heteroptera： Tingidae） reared on almond

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2007年第6期14卷 461-466页

作者： OZLEM cakmak MEHMET BASHAN HALIL BOLU Department of Biology Education Faculty Department of Biology Science and Art Faculty Department of Plant Protection AgricultureFaculty Dicle University 21280 Diyarbakir Turkey

The changes in fatty acid compositions during nutritional interaction among almond Amygdalus communis Linnaeus （Rosales： Rosaceae）（host plant）, lacebug Monosteria unicostata （Mulsant and Rey）（Heteroptera： Tingidae） and its predator Piocoris luridus Fieber （Heteroptera： Lygaeidae） were determined by gas chromatography and gas chromatography-mass spectrometry analyses. The fatty acid profiles of phospholipids and triacylglycerols were substantially different. Unlike the general observations for virtually most terrestrial insects, arachidonic and eicosapentaenoic acids were detected in high proportions of phospholipid fractions in both insects, especially in P. luridus. Also the almond tissues provide very little oleic acid to the herbivore diet, yet both insect species developed high proportions of this component. Our data reveals instances of specific accumulation of fatty acid biosynthesis, elongation/desaturation, and not incorporating selected fatty acids into cellular lipids.

关键词： Arachidonic acid insect fatty acid Monosteria unicostata Piocoris luridus,phospholipids triacylglycerols

Notes on Curves at a Constant Distance from the Edge of Regression on a Curve in Galilean 3-Space G_(3)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2023年第6期135卷 2731-2742页

作者： Ali cakmak Sezai Kızıltug Gokhan Mumcu Department of Mathematics Faculty of Arts and SciencesBitlis Eren UniversityBitlis13000Turkey Graduate School of Natural and Applied Sciences Erzincan Binali Yıldırım UniversityErzincan24002Turkey Department of Mathematics Faculty of Arts and ScienceErzincan Binali Yıldırım UniversityErzincan24002Turkey

In this paper,we define the curve rλ=r+λd at a constant distance from the edge of regression on a curve r(s)with arc length parameter s in Galilean ***,d is a non-isotropic or isotropic vector defined as a vector tightly fastened to Frenet trihedron of the curve r(s)in 3-dimensional Galilean *** build the Frenet frame{Tλ,Nλ,Bλ}of the constructed curve rλwith respect to two types of the vector d and we indicate the properties related to the curvatures of the curve rλ.Also,for the curve rλ,we give the conditions to be a circular ***,we discuss ruled surfaces of type A generated via the curve rλand the vector D which is defined as tangent of the curve rλin 3-dimensional Galilean *** constructed ruled surfaces also appear in two *** first is constructed with the curve rλ(s)=r(s)+λT(s)and the non-isotropic vector *** second is formed by the curve rλ=r(s)+λ2N+λ3B and the non-isotropic vector *** calculate the distribution parameters of the constructed ruled surfaces and we show that the ruled surfaces are ***,we provide examples and visuals to back up our research.

关键词： Edge of regression Galilean space curvature helix ruled surface

Synergistic and antagonistic interactions between potassium and magnesium in higher plants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2021年第2期9卷 249-256页

作者： Kailiu Xie Ismail cakmak Shiyu Wang Fusuo Zhang Shiwei Guo Jiangsu Provincial Key Lab of Solid Organic Waste Utilization Jiangsu Collaborative Innovation Center of Solid Organic WastesEducational Ministry Engineering Center of Resource-saving FertilizersNanjing Agricultural UniversityNanjing 210095JiangsuChina School of Land Resources and Environment Jiangxi Agricultural UniversityNanchang 330045JiangxiChina Faculty of Engineering and Natural Sciences Sabanci University34956 IstanbulTurkey International Magnesium Institute College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina College of Resources and Environmental Sciences China Agricultural UniversityBeijing 100193China

Magnesium(Mg)affects various critical physiological and biochemical processes in higher plants,and its deficiency impedes plant growth and *** potassium(K)-induced Mg deficiency in agricultural production is widespread,the specific relationship of K with Mg and especially its competitive nature is poorly *** review summarizes current knowledge on the interactions between K and Mg with respect to their root uptake,root-to-shoot translocation and distribution in *** synergistic effects on certain physiological functions are also *** antagonistic effect of K on Mg is stronger than that of Mg on K in root absorption and transport within plants,indicating that the balanced use of K and Mg fertilizers is necessary for sustaining high plant-available Mg and alleviating K-induced Mg deficiency,especially in plant species with high K demand or in highavailable-K *** relationship between Mg and K in plant tissues may be antagonistic or synergistic depending on plant species,cell type,leaf age,source-and sink *** are synergistic effects of K and Mg on photosynthesis,carbohydrate transport and allocation,nitrogen metabolism,and turgor *** of optimal K/Mg ratios for soils and plant tissues is desirable for maintaining proper nutritional status in plants,leading to a physiological state supporting crop *** research should concentrate on identifying the physiological and molecular mechanisms underlying the interactions between K and Mg in a given physiological function.

关键词： Antagonism Functional replacement Magnesium Potassium Synergy

Cold activeα-amylase obtained from Cladophora hutchinsiae-Purification,biochemical characterization and some potential applications

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第6期50卷 725-732页

作者： Ummuhan cakmak Fulya Oz Tuncay Yakup Kolcuoğlu Faculty of Science Department of ChemistryKaradeniz Technical UniversityTrabzonTurkey

The amylase obtained from Cladophora hutchinsiae was purified by the starch affinity method(11.4-fold and specific activity of 89.7±2.6 U/mg protein)and examined for its biochemical characterization,thermodynamic properties,and use in some industrial *** a result of SDS-PAGE analysis,the presence of a single band of 66.2 kDa was *** was determined that the enzyme showed optimum activity at pH 6.00 and 10°*** the presence of soluble starch as substrate,Km,Vmax and kcat values were calculated as 1.49±0.03 mg/mL,0.18±0.01 U and 0.003 s−*** enzyme demonstrated remarkable pH *** activity was investigated in a medium containing some organic solvent and *** amylase was inhibited by ethanol,acetonitrile,glycerol,and acetone(10%),no change in activity was observed in the presence of *** addition,it was determined that while Cu2+and Hg2+metal ions(5 mM)effectively inhibited the amylase enzyme,Ca2+ion activates the amylase *** activation energy(Ea)was calculated as at 28.3 kJ mol−*** was also found to be effective in releasing the reducing sugar from different fruit juice and fish *** amount of reducing sugar released as a result of incubation of fruit juices with enzyme for 3 h was observed the most in apple juice(from 1658.3±33.8μg/mL to 1945.6±36.7μg/mL)and the increase in the amount of reducing sugar was found to be 1.53 times in fish *** to the results obtained from the study,it can be said that the amylase obtained from seaweed can be used in different industrial areas.

关键词： Seaweed Cladophora hutchinsiae Purification α-Amylase

Long term diazotrophic cultivation induces phycobiliprotein production in Anabaena variabilis IMU8

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIOCELL 2019年第4期43卷 327-333页

作者： MOHAMMED FADHIL HADDAD TUGBA DAYIOGLU BARBAROS NALBANTOGLU TURGAY cakmak Department of Molecular Biology and Genetics Faculty of Engineering and Natural SciencesIstanbul Medeniyet University34730IstanbulTurkey Department of Chemistry Faculty of Arts and SciencesYildiz Technical University34220IstanbulTurkey Mosul Technical Institute Northern Technical University41002MosulIraq

Cyanobacteria are considered as a sustainable feedstock for the production of biochemically active compounds such as phycobiliproteins(PBPs).In this study,the impact of nitrogen(N)and phosphorus(P)availability on PBP production of“N-free acclimated”Anabaena variabilis IMU8 was *** isolation and identification,the cyanobacterium has been maintained in N-free BG-11 medium for more than 20 *** experimentation,the strain was incubated in N-replete,N-depleted,N-P-depleted BG-11 ***-term diazotrophic cultivation of *** IMU8 resulted in elevated PBP productivity with a limited impact on *** compared to N-depleted ones,N supply stimulated a slight induction of growth and total saccharide production,but total protein content did not change while PBP production *** the other hand,N-P-depletion resulted in decreased growth rate along with reduced total protein and PBP production while rapid induction of total saccharide production was *** transform infrared spectroscopy results refer that membrane-bound oligosaccharides may have regulatory roles for PBP production in *** IMU8 during long term diazotrophic cultivation.

关键词： Cyanobacteria Nitrogen Phosphorus Phycobiliprotein

A 3D in vitro co-culture model for evaluating biomaterial-mediated modulation of foreign-body responses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2022年第3期5卷 465-480页

作者： Betul cakmak Pelin Saglam-Metiner Goze Beceren Yu S.Zhang Ozlem Yesil-Celiktas Department of Bioengineering Faculty of EngineeringEge University35100 IzmirTurkey Division of Engineering in Medicine Brigham and Women’s HospitalDepartment of MedicineHarvard Medical SchoolCambridgeMAUSA

The immune response after implantation of a biomaterial may shorten the functional life of the implant,depending on the degree of the *** this study,we used a polyacrylamide-alginate(PAAm-Alg)hydrogel,which has been previously characterized as a biocompatible material and shown to enhance regeneration of cartilage in vivo,along with a graphiteenhanced hydrogel(PAAm-Alg-G)as a non-biocompatible counterpart,to evaluate macrophage attachment and polarization to pro-or anti-inflammatory *** performance of each biomaterial in the presence of fibroblasts and chondrocytes was validated by an in vitro model which demonstrated modulation of the foreign-body response.A blend of 5%gelatin methacryloyl and 0.1%methacrylated hyaluronic acid was optimized to mimic the extracellular matrix(ECM)and support cell viability,proliferation,migration,and functionality at an initial concentration of 3.25×10^(5) cells/*** PAAm-Alg-G hydrogel localized in the simulated ECM showed cytotoxic and genotoxic effects for both fibroblasts and chondrocytes,while exhibiting a proliferative effect on macrophages with elevated immune *** M1/M2 ratio was 0.73 for PAAm-Alg hydrogel but 2.64 for PAAm-Alg-G,leading to significant M1 dominance(p0.05).The interleukin-6(IL-6)concentration secreted in the presence of PAAm-Alg hydrogel(4.58 pg/mL)significantly decreased(p<0.0001)on day 13,while the increase(p<0.0001)in interleukin-10(IL-10)concentration(120.73 pg/mL)confirmed the switch from a pro-inflammatory to an anti-inflammatory *** immune responses by developing a simplistic yet powerful three-dimensional in vitro model provides advantages in preparing for clinical use of biomaterials.

关键词： Biomaterial Macrophage polarization Genotoxicity Biocompatibility Immune response

Corneal white-to-white distance and mesopic pupil diameter

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2012年第4期5卷 505-509页

作者： Hasan Basri cakmak Nurullah Cagil Huseyin Simavli Sabri Raza Yildirim Beyazit Universitesi Ataturk Egitimve Arastirma HastanesiBilkent yolu No: 3 Bilkent Ankara Turkey Bolu State Hospital Bolu Turkey Ankara Atatürk Education and Research Hospital Ankara Turkey

·AIM:To study the relationship between corneal white-to- white (WTW) distance and mesopic pupil diameter. ·METHODS:This study is composed of 30 cases that underwent photorefractive keratotomy (PRK). Pupil size measurements were performed with Schwind ORK wavefront analyzer in mesopic conditions. WTW distance was measured with a measuring caliper. Also, A-scan ultrasound examination was performed in all patients. The relationship among the mesopic pupil diameter and age, sex, axial length, lens thickness, anterior chamber depth(ACD), horizontal WTW distance, vertical WTW distance, spherical equivalent, and average keratometry were analyzed with univariate and multivariate regression analysis. ·RESULTS:Mean pupil diameter was (6.39±0.80)mm (range:3.70mm to 7.73mm. Horizontal WTW distance measurements were between 11.00mm and 12.50mm and mean horizontal WTW distance was (11.79±0.43)mm. On the other hand, vertical WTW distances ranged between 10.00mm and 13.00mm, and their mean was(11.42±0.72)mm. Bivariate correlation between pupil diameter and other variables showed that the axial length, ACD, spherical equivalent, and horizontal WTW distance had a moderate correlation with mesopic pupil diameter. Multiple regression analysis revealed that spherical equivalent and horizontal WTW distances were significantly associated with mesopic pupil diameter (R =0.598, R 2=0.358 P =0.02). ·CONCLUSION:This study shows that mesopic pupil diameter is closely related to horizontal WTW distance. These two factors must be taken in consideration together in preoperative ablation zone planning.

关键词： mesopic pupil diameter photorefractive keratectomy white-to-white distance

A statistical approach to classification of keratoconus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2016年第9期9卷 1355-1357页

作者： Murat Ucar Hasan Basri cakmak Baha Sen Department of Computer Engineering Karabk University Faculty of Engineering Department of Ophthalmology Hacettepe University Faculty of Medicine Department of Computer Engineering Yildirim Beyazit University Faculty of Engineering and Natural Sciences

INTRODUCTIONThe front portion of the eye consists of a transparent layer called the *** cornea is an important optical component for vision and plays a role in the specific refraction of the *** cornea normally has convexity but the amount of protrusion progressively increases in patients with *** other words,the cornea prolapses *** is a bilateral,typically asymmetric and non-inflammatory degeneration of the cornea caused by corneal protrusion as a result of progressive thinning of the corneal *** thinning generally occurs in the inferior,inferotemporal or central regions of the cornea.

关键词： A statistical approach to classification of keratoconus