检索结果-南通市图书馆

Serological investigation of IgG and IgE antibodies against food antigens in patients with inflammatory bowel disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第16期7卷 2189-2203页

作者： Hai-Yang Wang Yi li Jia-Jia li Chun-Hua jiao Xiao-Jing Zhao Xue-Ting li mei-jiao Lu Xia-Qiong Mao Hong-Jie Zhang Department of Gastroenterology The Affiliated Sir Run Run HospitalNanjing Medical UniversityNanjing 211100Jiangsu ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina

BACKGROUND Food antigens have been shown to participate in the etiopathogenesis of inflammatory bowel disease (IBD),but their clinical value in IBD is still *** To analyze the levels of specific immunoglobulin G (IgG) and E (IgE) antibodies against food antigens in IBD patients and to determine their clinical value in the pathogenesis of *** We performed a retrospective study based on patients who visited the First Affiliated Hospital of Nanjing Medical University between August 2016 and January 2018.A total of 137 IBD patients,including 40 patients with ulcerative colitis (UC) and 97 patients with Crohn’s disease (CD),and 50 healthy controls (HCs),were *** food-specific IgG antibodies were detected by semiquantitative enzyme-linked immunosorbent assay,and serum food-specific IgE antibodies were measured by Western *** value of food-specific IgG antibodies was compared among different groups,and potent factors related to these antibodies were explored by binary logistic *** Food-specific IgG antibodies were detected in 57.5% of UC patients,in 90.72% of CD patients and in 42% of HCs.A significantly high prevalence and titer of foodspecific IgG antibodies were observed in CD patients compared to UC patients and *** number of IgG-positive foods was greater in CD and UC patients than in HCs (CD vs HCs,P = 0.000;UC vs HCs,P = 0.029).The top five food antigens that caused positive specific IgG antibodies in CD patients were tomato (80.68%),corn (69.32%),egg (63.64%),rice (61.36%),and soybean (46.59%).The foods that caused positive specific IgG antibodies in UC patients were egg (60.87%),corn (47.83%),tomato (47.83%),rice (26.09%),and soybean (21.74%).Significantly higher levels of total food-specific IgG were detected in IBD patients treated with anti-TNFα therapy compared to patients receiving steroids and immunosuppressants (anti-TNFα vs steroids,P = 0.000;anti-TNFα vs immunosuppressants,P = 0.000;anti-TNFα vs steroids

关键词： Inflammatory bowel disease Food-specific immunoglobulin G Food intolerance

Internal state variable models for micro-structure in high temperature deformation of titanium alloys

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2008年第11期51卷 1921-1929页

作者： LUO jiao li MiaoQuan li Xiaoli School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China

There exists an interaction between microstructural evolution and deformation behavior in high temperature deformation of titanium alloys. And the microstruc- ture of titanium alloys is very sensitive to the process parameters of plastic de- formation process. In this paper, on the basis of plastic deformation mechanism of metals and alloys, a microstructural model including dislocation density rate equa- tion and grain growth rate equation is established with the dislocation density rate being an internal state variable. Applying the model to the high temperature de- formation process of Ti60 titanium alloy, the average relative errors of grain sizes between the experiments and the predictions are 9.47% for sampled data, and 13.01% for non-sampled data.

关键词： titanium alloy grain size dislocation density models parameter recognition

Changes in the esophagogastric junction outflow obstruction manometric feature based on the Chicago Classification updates

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第30期28卷 4163-4173页

作者： Yue-Yuan li Wen-Ting Lu Jian-Xiang liu li-Hong Wu Meng Chen Hong-mei jiao Department of Geriatrics Peking University First HospitalBeijing 100034China Department of Gastroenterology and Hepatology Peking University First HospitalBeijing 100034China

BACKGROUND The critical diagnostic criteria for esophagogastric junction outflow obstruction(EGJOO)were published in the latest Chicago Classification version 4.0(CCv4.0).In addition to the previous criterion[elevated integrated relaxation pressure(IRP)in supine position],manometric diagnosis of EGJOO requires meeting the criteria of elevated median-IRP during upright wet swallows and elevated intrabolus ***,with the diagnostic criteria modification,the change in manometric features of EGJOO remained *** To evaluate the esophageal motility characteristics of patients with EGJOO and select valuable parameters for confirming the diagnosis of *** We performed a retrospective analysis of 370 patients who underwent highresolution manometry with 5 mL water swallows×10 in supine,×5 in upright position and the rapid drink challenge(RDC)with 200 mL water from November 2016 to November 2021 at Peking University First ***-one patients with elevated integrated supine IRP and evidence of peristalsis were enrolled,with 24 patients meeting the updated manometric EGJOO diagnosis(CCv4.0)as the EGJOO group and 27 patients not meeting the updated EGJOO criteria as the isolated supine IRP elevated group(either normal median IRP in upright position or less than 20%of supine swallows with elevated IBP).Forty-six patients with normal manometric features were collected as the normal high-resolution manometry(HRM)*** esophageal sphincter(UES),esophageal body,and lower esophageal sphincter(LES)parameters were compared between *** Compared with the normal HRM group,patients with EGJOO(CCv4.0)had significantly lower proximal esophageal contractile integral(PECI)and proximal esophageal length(PEL),with elevated IRP on RDC(Plities in the esophagogastric junction than isolated supine IRP elevate

关键词： Esophagogastric junction outflow obstruction High-resolution manometry Esophageal motility disorders Upper esophageal sphincter Proximal esophagus

Resonances in Positron Hydrogen Scattering above the H (n=2) Threshold

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2012年第5期29卷 93-96页

作者： YU Rong-mei CHENG Yong-Jun jiao li-Guang ZHOU Ya-Jun Center for Theoretical Atomic and Molecular Physics Academy of Fundamental and Interdisciplinary ScienceHarbin Institute of TechnologyHarbin 150080

We investigate high partial wave resonances in positron-hydrogen scattering using the momentum-space coupledchannels optical method above the H (n =2) *** with angular momenta of L =0-6 are *** continuum and positronium formation channels are included via a complex equivalent local *** with the existing theoretical results are presented.

关键词： potential momentum

Multi-physical field coupling simulation of TCVI process for preparing carbon/carbon composites

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2009年第11期52卷 3173-3179页

作者： jiao YanQiong li HeJun li KeZhi Research Center of Carbon/Carbon Composites Laboratory of Thermostructure Composite MaterialsNorthwestern Polytechnical UniversityXi’an 710072China

To prepare Carbon/Carbon (C/C) composites with advanced performance, the thermal gradient chemical vapor infiltration (TCVI) process has been optimized by simulation. A 2D axisymmetric unstable model was built, which included convection, conduction, diffusion, densification reactions in the pores and the evolution of the porous medium. The multi-physical field coupling model was solved by finite element method (FEM) and iterative calculation. The time evolution of the fluid, temperature and preform density field were obtained by the calculation. It is indicated that convection strongly affects the temperature field. For the preform of carbon/carbon composites infiltrated for 100 h by TCVI, the radial average densities from simulation agrees well with those from experiment. The model is validated to be reliable and the simulation has capability of forecasting the process.

关键词： C/C composites TCVI multi-physical field coupling simulation

Numerical and experimental analyses of methane leakage in shield tunnel

在线全文

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2023年第7期17卷 1011-1020页

作者： Jie HE Hehua ZHU Xiangyang WEI Rui JIN Yaji jiao mei YIN College of Civil Engineering Tongji UniversityShanghai 200092China State Key Laboratory for Disaster Reduction in Civil Engineering Tongji UniversityShanghai 200092China Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Tongji UniversityShanghai 200092China d Department of Civil and Environmental EngineeringBrunel UniversityLondon UB83PHUK

Tunnels constructed in gas-bearing strata are affected by the potential leakage of harmful gases,such as methane *** on the basic principles of computational fluid dynamics,a numerical analysis was performed to simulate the ventilation and diffusion of harmful gases in a shield tunnel,and the effect of ventilation airflow speed on the diffusion of harmful gases was *** the airflow speed increased from 1.8 to 5.4 m/s,the methane emission was diluted,and the methane accumulation was only observed in the area near the methane leakage *** influence of increased ventilation airflow velocity was dominant for the ventilation modes with two and four *** addition,laboratory tests on methane leakage through segment joints were *** results show that the leakage process can be divided into“rapid leakage”and“slight leakage”,depending on the leakage pressure and the state of joint *** on the numerical and experimental analysis results,a relationship between the safety level and the joint deformation is established,which can be used as guidelines for maintaining utility tunnels.

关键词： shield tunnel harmful gas leakage numerical analysis laboratory test

A real-time inversion attack on the GMR-2 cipher used in the satellite phones

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2018年第3期61卷 157-174页

作者： jiao HU Ruilin li Chaojing TANG College of Electronic Science National University of Defense Technology

The GMR-2 cipher is a type of stream cipher currently being used in some inmarsat satellite phones. It has been proven that such a cipher can be cracked using only one single-frame（15 bytes） known keystream but with moderate executing time. In this paper, we present a new thorough security analysis of the GMR-2 cipher. We first study the inverse properties of the cipher's components to reveal a bad one-way character of the cipher. By then introducing a new concept called "valid key chain" according to the cipher's key schedule, we propose an unprecedented real-time inversion attack using a single-frame keystream. This attack comprises three phases:（1） table generation;（2） dynamic table look-up, filtration and combination;and（3） verification. Our analysis shows that, using the proposed attack, the size of the exhaustive search space for the 64-bit encryption key can be reduced to approximately 213when a single-frame keystream is available. Compared with previous known attacks, this inversion attack is much more efficient. Finally, the proposed attack is carried out on a 3.3-GHz PC, and the experimental results thus obtained demonstrate that the 64-bit encryption-key could be recovered in approximately 0.02 s on average.

关键词： satellite phone stream cipher GMR-2 cryptanalysis inversion attack

Individual aircraft life monitoring： An engineering approach for fatigue damage evaluation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2018年第4期31卷 727-739页

作者： Rui jiao Xiaofan HE Yuhai li School of Aeronautic Science and Engineering Beihang University Beijing 100083 China A viation Industry Corporation of China Beijng 100022 China

Individual aircraft life monitoring is required to ensure safety and economy of aircraft structure, and fatigue damage evaluation based on collected operational data of aircraft is an integral part of it. To improve the accuracy and facilitate the application, this paper proposes an engineering approach to evaluate fatigue damage and predict fatigue life for critical structures in fatigue monitoring. In this approach, traditional nominal stress method is applied to back calculate the S-N curve parameters of the realistic structure details based on full-scale fatigue test data. Then the S-N curve and Miner＇s rule are adopted in damage estimation and fatigue life analysis for critical locations under individual load spectra. The relationship between relative small crack length and fatigue life can also be predicted with this approach. Specimens of 7 B04-T74 aluminum alloy and TA15 M titanium alloy are fatigue tested under two types of load spectra, and there is a good agreement between the experimental results and analysis results. Furthermore, the issue concerning scatter factor in individual aircraft damage estimation is also discussed.

关键词： Fatigue damage Fatigue monitoring Fatigue test Scatter factor S-N curve

Support vector classifier based on principal component analysis

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2008年第1期19卷 184-190页

作者： Zheng Chunhong jiao licheng li Yongzhao School of Electronic Engineering Xidian Univ. Xi'an 710071 P. R. China

Support vector classifier （SVC） has the superior advantages for small sample learning problems with high dimensions, with especially better generalization ability. However there is some redundancy among the high dimensions of the original samples and the main features of the samples may be picked up first to improve the performance of SVC. A principal component analysis （PCA） is employed to reduce the feature dimensions of the original samples and the pre-selected main features efficiently, and an SVC is constructed in the selected feature space to improve the learning speed and identification rate of SVC. Furthermore, a heuristic genetic algorithm-based automatic model selection is proposed to determine the hyperparameters of SVC to evaluate the performance of the learning machines. Experiments performed on the Heart and Adult benchmark data sets demonstrate that the proposed PCA-based SVC not only reduces the test time drastically, but also improves the identify rates effectively.

关键词： support vector classifier principal component analysis feature selection genetic algorithms