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Chinese Physics B 2021年第4期30卷 535-541页

作者： Lu Xue Yi Li mei ge mei-Yu Wang You-Hua Zhu School of Information Science and Technology&Tongke School of Microelectronics Nantong UniversityNantong 226019China

The optical properties of AlGaN-based quantum well(QW)structure with two coupled thin well layers are investigated by the six-by-six K-P *** with the conventional structure,the new structure,especially the one with lower Al-content in the barrier layer,can enhance the TE-/TM-polarized total spontaneous emission rate due to the strong quantum confinement and wide recombination *** the conventional QW structure,the reduction of well thickness can lead the degree of polarization(DOP)to decrease and the internal quantum efficiency(IQE)to *** using the coupled thin well layers,the DOP for the structure with high Al-content in the barrier layer can be improved,while the DOP will further decrease with low Al-content in the barrier *** can be attributed to the band adjustment induced by the combination of barrier height and well layer *** IQE can also be further enhanced to 14.8%-20.5%for various Al-content of barrier layer at J=100 A/cm^(2).In addition,the efficiency droop effect can be expected to be suppressed compared with the conventional structure.

关键词： Al Ga N-based quantum well K-P method internal quantum efficiency degree of polarization

Enhanced valley splitting of WSe_(2)in twisted van der Waals WSe_(2)/CrI_(3)heterostructures

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npj Computational Materials 2022年第1期8卷 277-283页

作者： mei ge Han Wang Jizheng Wu Chen Si Junfeng Zhang Shengbai Zhang School of Physics and Information Engineering Shanxi Normal UniversityTaiyuanChina Chemical Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCAUSA School of Materials Science and Engineering Beihang UniversityBeijingChina Department of Physics Applied Physicsand AstronomyRensselaer Polytechnic InstituteTroyNYUSA

Van der Waals(vdW)heterostructures composed of different two-dimensional(2D)materials offer an easily accessible way to combine properties of individual materials for *** to the discovery of a set of unanticipated physical phenomena,the twisted 2D vdW heterostructures have gained considerable attention ***,we report enhanced valley splitting in twisted 2D vdW WSe_(2)/CrI_(3)*** particular,the splitting can be 1200%(or 5.18 meV)of the value for a non-twisted *** to the k·p model,this value is equivalent to a~20 T external magnetic field applied perpendicular to the 2D *** thermodynamic stability of 2D vdW WSe_(2)/CrI_(3)heterostructures,on the other hand,depends linearly on the interlayer twisting angle.

关键词： twisted splitting gained

Assessment of the potential toxicity of insecticidal compounds to Peristenus spretus,a parasitoid of mirid bugs

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Journal of Integrative Agriculture 2022年第5期21卷 1424-1435页

作者： ZHAO Man LI Yun-he NIU Lin-lin CHEN Lin LIANG ge-mei State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China College of Plant Protection Henan Agricultural UniversityZhengzhou 450002P.R.China

With the increased cultivation of Bt crops in China,Apolygus lucorum and other mirid bugs have emerged as important agricultural pests because they are insensitive to the Bt *** addition,the reduction of pesticide applications after planting Bt crops also increases the severity of mirid bug *** spretus is a parasitoid of mirid nymphs,but its sensitivity to Bt proteins is not *** the current study,we developed a dietary exposure assay to assess the effects of Bt proteins(Cry1Ab,Cry1Ac,Cry1F,Cry2Aa,and Cry2Ab)on *** adults using a diet consisting of a 10% honey solution with or without Bt proteins at 400μg g^(-1) *** results showed that the survival and reproduction of *** adults were reduced by the cysteine protease inhibitor E-64(a positive control)but were not affected by any of the five Bt *** activities of digestive,detoxifying,and antioxidant enzymes in *** were also unaffected by diets containing the Cry proteins,but they were significantly affected by the diet containing *** then developed a tritrophic bioassay to determine the effects of the five Bt proteins on *** larvae and *** this assay,*** nymphs fed an artificial diet containing Cry proteins were used as the hosts for *** results of the tri-trophic assay indicated that neither the pupation rate nor the eclosion rate of the *** parasitoids were significantly affected by the presence of high concentrations of Bt proteins in the parasitized *** *** overall results indicate that these two assays can be used to evaluate the toxicity of insecticidal compounds to *** and that the tested Cry proteins are not toxic to ***.

关键词： transgenic crops plant bugs parasitic natural enemy Cry proteins non-target risk assessment

Effect of surface plasmon coupling with radiating dipole on the polarization characteristics of AlGaN-based light-emitting diodes

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Chinese Physics B 2022年第7期31卷 573-578页

作者： Yi Li mei ge meiyu Wang Youhua Zhu Xinglong Guo School of Information Science and Technology&Tongke School of Microelectronics Nantong UniversityNantong 226019China

The optical polarization characteristics of surface plasmon(SP)coupled Al Ga N-based light emitting diodes(LEDs)are investigated theoretically by analyzing the radiation recombination process and scattering process *** the Al_(0.5)Ga_(0.5)N/Al/Al_(2)O_(3)slab structure,the relative intensity of TE-polarized and TM-polarized spontaneous emission(SE)rate into the SP mode obviously depends on the thickness of the Al *** calculation results show that TM dominated emission will be transformed into TE dominated emission with the decrease of the Al thickness,while the emission intensities of both TE/TM polarizations will decrease *** addition,compared with TM polarized emission,TE polarized emission is easier to be extracted by SP *** the Al_(0.5)Ga_(0.5)N/Al nano-particle structure,the ratio of transmittance for TE/TM polarized emission can reach~3.06,while for the Al free structure,it is only ***,the degree of polarization of SP coupled LED can be improved by the reasonable structural design.

关键词： surface plasmon AlGaN-based light emitting diodes FDTD K-P method

Performance of Three Adelphocoris spp.(Hemiptera: Miridae) on Flowering and Non-flowering Cotton and Alfalfa

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Journal of Integrative Agriculture 2014年第8期13卷 1727-1735页

作者： GAO Zhen PAN Hong-sheng LIU Bing LU Yan-hui LIANG ge-mei State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences

The genus Adelphocoris（Hemiptera： Miridae） is a group of key insect pests in cotton fields in China that includes three dominant species： A. suturalis（Jakovlev）, A. lineolatus（Goeze） and A. fasciaticollis（Reuter）. Previous field surveys have found that adults of these Adelphocoris species usually move onto specific host plants when the plants enter the flowering stage. To determine the potential trade-offs for this host-plant preference behavior, the performance of these three Adelphocoris spp. on flowering and non-flowering cotton and alfalfa were compared in the laboratory. The results showed that Adelphocoris spp. had significantly higher nymphal developmental and survival rates, along with increased adult longevity and fecundity on flowering cotton and alfalfa than on non-flowering plants of either species. In addition, compared with cotton plants, alfalfa generally promoted better performance of these three Adelphocoris species, especially for A. lineolatus. Simple correlation analysis indicated that female adult longevity was positively correlated to male adult longevity and female fecundity, and female fecundity was positively correlated to nymphal development and survival rates. This study demonstrated a positive correlation between adult preference and offspring/adult performance for all three Adelphocoris species, with no evidence of any trade-offs for this preference for flowering host plants. These findings support the hypothesis that hemimetabolous insects such as mirid bugs have positive adult preference-adult/nymphal performance relationships, which is likely due to the similar feeding habits and nutritional requirements of adults and nymphs.

关键词： Adelphocoris lineolatus Adelphocoris suturalis Adelphocoris fasciaticollis preference-performance relationship cotton alfalfa flowering stage

Synthesis and VEGF inhibitory activity of 16,17-pyrazo-annulated steroids

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Chinese Chemical Letters 2011年第7期22卷 757-760页

作者： Hong Shan Liu Hu Ling Zheng mei ge Peng Xia Ying Chen Department of Medicinal Chemistry School of Pharmacy Fudan University Shanghai 201203 China Laiyi Biological Drug Research and Development Center Co. Ltd. Shanghai 201203 China

Eight 16,17-pyrazo-annulated steroidal derivatives were synthesized and evaluated in vitro vascular endothelial growth factor （VEGF） inhibitory activity with 2-methoxyestradiol （2-ME） as the reference compound. Most of the compounds showed potent VEGF inhibitory activity with ECs0 values of micromolar or submicromolar range. Among them, the compounds 3 and 8 exhibited similar EC50 values and obviously better TI values compared with 2-ME.

关键词： Pyrazo-annulated steroid 2-Methoxyestradiol (2-ME) VEGF inhibitory activity

Alanine-substituted mutant on Gly^(373) and Asn^(375) of Cry1Ai-h-loop 2 causes reduction in both toxicity and binding against Helicoverpa armigera

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Journal of Integrative Agriculture 2019年第5期18卷 1064-1071页

作者： LIU Yu-xiao ZHOU Zi-shan LIANG ge-mei SONG Fu-ping ZHANG Jie State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences

Cry1Ai-h-loop 2 is a mutant of Cry1Ai constructed by exchanging loop 2 from Cry1Ah protein and shows insecticidal activity against Helicoverpa armigera. The toxicity of Cry1 Ai-h-loop 2, in contrast to the very low toxicity of Cry1Ai, is closely associated with the eleven residues in the loop 2 region. To characterize the key sites of loop 2 in Cry1Ai-h-loop 2, alaninesubstituted mutants were generated. The toxicity of these mutants against H. armigera indicated that dual-mutant on Gly373 and Asn375 caused a significant decrease in toxic activity. ELISA binding and competition binding assays demonstrated that the reduction of toxicity in the mutant of interest was correlated with decreased binding affinity.

关键词： Bacillus thuringiensis Cry1Ai Domain Ⅱ-loop2 Helicoverpa armigera binding affinity

Application of endoscopic hemoclips for nonvariceal bleeding in the upper gastrointestinal tract

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World Journal of Gastroenterology 2009年第34期15卷 4322-4326页

作者： Shi-Bin Guo Ai-Xia Gong Jing Leng Jing Ma Lin-mei ge Department of Gastroenterology the Affiliated First Hospital of Dalian Medical University Dalian 116001 Liaoning Province China

AIM： To investigate acute nonvariceal bleeding in the upper gastrointestinal （GI） tract and evaluate the effects of endoscopic hemoclipping. METHODS： Sixty-eight cases of acute nonvariceal bleeding in the upper GI tract were given endoscopic treatment with hemoclip application. Clinical data, endoscopic findings, and the effects of the therapy were evaluated. RESULTS： The 68 cases （male：female = 42：26, age from 9 to 70 years, average 54.4） presented with hernatemesis in 26 cases （38.2%）, melena in nine cases （13.3%）, and both in 33 cases （48.5%）. The causes of the bleeding included gastric ulcer （29 cases）, duodenal ulcer （11 cases）, Dieulafoy＇s lesion （11 cases）, Mallory-Weiss syndrome （six cases）, post-operative （three cases）, post-polypectomy bleeding （five cases）, and post-sphincterotomy bleeding （three cases）; 42 cases had active bleeding. The mean number of hemoclips applied was four. Permanent hemostasis was obtained by hemoclip application in 59 cases; 6 cases required emergent surgery （three cases had peptic ulcers, one had Dieulafoy＇s lesion, and two were caused by sphincterotomy）; three patients died （two had Dieulafoy＇s lesion and one was caused by sphincterotomy）; and one had recurrent bleeding with Dieulafoy＇s lesion 10 mo later, but in a different location. CONCLUSION： Endoscopic hemoclip application was an effective and safe method for acute nonvariceal bleeding in the upper GI tract with satisfactory outcomes.

关键词： Gastrointestinal hemorrhage Endoscopy Hemoclip Hemostasis

An eIF3a gene mutation dysregulates myocardium growth with left ventricular noncompaction via the p-ERK1/2 pathway

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genes & Diseases 2021年第4期8卷 545-554页

作者： mei ge Xuehan Bai Aoyi Liu Lingjuan Liu Jie Tian Tiewei Lu Department of Cardiology Children’s Hospital of Chongqing Medical UniversityChongqing401122PR China China International Science and Technology Cooperation Center for Child Development and Critical Disorders Chongqing Key Laboratory of PediatricsMinistry of Education Key Laboratory of Child Development and DisordersChongqing401122PR China

Left ventricular noncompaction(LVNC)is a heterogeneous disorder with undlear genetic causes and an unknown ***3a,an important member of the Eukaryotic translation initiation factor 3(elF3)family,is involved in multiple biological processes,indluding cell prolif eration and migration during myocardial development,suggesting it could play a role in LVNC *** investigate the association between a novel variant(C.1145 A->G)in elF3a and LVNC,and explore potential mechanisms that could lead to the development of LVNC.A novel elF3a variant,C.1145 A->G,was identified by whole-exome sequencing in a familial pedigree with *** vectors containing wild-type elF 3a and the mutated version were constructed and co-infected into H9C2 *** proliferation,apoptosis,cell migration,and differentiation,as well as phosphorylation of ERK1/2 were stud-ied and were measured by proliferation assays,flow cytometry,real-time PCR and Westem blot,*** elF3a mutation inhibited the proliferation of H9C2 cells,induced apoptosis,promoted cell migration,and inhibited the dif ferentiation of human induced plurip-otent stem cell-derived cardiomyocytes(hiPSC-CMs).The effect of the elF3a mutation may be attributed to a decrease in expression of p-ERK1/2.A novel elF3a gene mutation disrupted the p-ERK1/2 pathway and caused decreased myocardium proliferation,differentiation,acceler-ated *** finding may provide some insight into the mechanism involved in LVNC development.

关键词： Differentiation eIF3a mutation Left ventricular noncompaction(LVNC) Migration p-ERK1/2 Proliferation

Rutile in HP Rocks from the Western Tianshan,China:Mineralogy and Its Economic Implications

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Journal of Earth Science 2018年第5期29卷 1049-1059页

作者： Wen Su Jilei Li Qian Mao Jun Gao Xin Liu Fei Chen Xiao-mei ge State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Key Laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Beijing Institute of geology for Mineral Resources Beijing 100012China

Rutile is a common Ti-bearing accessory mineral in high pressure （HP） metamorphic rocks of the western Tianshan. Distribution of rutile in the HP rocks varies from 0.5% in the greenschist to 30% in the rutile-bearing vein. Rutile can be subdivided into three groups based on the variation of trace elements： The first group has an averaged Zr content of 18 ppm-44 ppm and Hf content of 0.8 ppm-2.4 ppm, which correspond to occurrence of rutile from vein; the second group Zr of 59 ppm-63 ppm, Hf of 3.5 ppm-3.7 ppm; and the third group Zr of 150 ppm-160 ppm and Hf of 3.9 ppm, corresponding to rutile in the matrix of blueschist and eclogite, respectively. Rutile has been retrograded to ilmenite and titanite partly or completely, reducing the value of the ore. But rutile of HP rocks in the western Tianshan usually has the lowest content of uranium （〈1 ppm U）, which might become an attractive raw material for the Ti industry. Therefore, rutile-bearing HP rocks in the western Tianshan as a mineral resource will be the focus of considerable attention.

关键词： Ti resource rutile HP vein eclogite western Tianshan.