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Evaluation of All-Sky Assimilation of FY-3C/MWHS-2 on mei-yu Precipitation Forecasts over the Yangtze-Huaihe River Basin

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Advances in Atmospheric Sciences 2021年第8期38卷 1397-1414页

作者： yu LI Keyi CHEN Zhipeng XIAN School of Atmospheric Sciences Chengdu University of Information TechnologyChengdu 610025China International Center for Climate and Environment Sciences Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China

All-sky (i.e., clear, cloudy, and precipitating conditions) assimilation of microwave observations shows potentially positive impacts on the improvement of the forecasts of cloud-associated weather processes. In this study, a typical mei-yu heavy precipitation event that occurred in 2017 was investigated, and the Weather Research and Forecasting data assimilation (WRFDA) as well as its 3D-Var assimilation scheme (excluding cloud and precipitation control variables) were applied to assimilate the Fengyun-3C (FY-3C) Microwave Humidity Sounder-2 (MWHS-2) observations under clear- sky (excluding the observations that are strongly affected by ice clouds and precipitation) and all-sky conditions. Three experiments including a control experiment without assimilating any observations, clear-sky, and all-sky experiments with only FY-3C/MWHS-2 observations assimilated were carried out. The results show that the all-sky assimilation approach that provides more cloud and precipitation information and increased more than 10% of the satellite data usage than the clear-sky experiment. Meanwhile, as compared with the control experiment, the all-sky assimilation reduced nearly 0.5% of the root mean square errors in the humidity fields, leading to more accurate forecast performances regarding the distribution and intensity of heavy rainfall;but it exhibited a neutral to negative impacts on the wind and temperature. Although the system used to conduct all-sky assimilation is only able to adjust control variables for moisture-, wind-, and temperature- related variables in the presence of cloud and does not benefit directly from cloud or precipitation information, the positive effects on heavy rainfall forecasts achieved in this study indicate a potential future benefit regarding disaster prevention and mitigation.

关键词： all-sky assimilation FY-3C MWHS-2 mei-yu rainfall

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Formation of Low-Level Jets over Southern China in the mei-yu Season

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Advances in Atmospheric Sciences 2023年第10期40卷 1731-1748页

作者： Xuanyu LIU Guixing CHEN Sijia ZHANG yu DU School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen UniversityZhuhai 519082China Key Laboratory of Tropical Atmosphere-Ocean System(Sun Yat-sen University) Ministry of EducationZhuhai 519082China

This study examines the diversity of low-level jet(LLJ)formation and related physical processes over southern China.A total of 171 LLJ formation events with enhanced daily southwesterlies and early-morning maximum wind speeds were observed during the mei-yu seasons of 1989–*** LLJs can be further categorized into four types based on the increases in the daily mean and diurnal amplitude of the low-level *** of the synoptic-scale disturbances shows that the two types of LLJ formation(Q1 and Q4),which feature large increases of daily southerly wind components,are mainly induced by west-east dipole patterns of pressure change,in association with the enhanced southwest vortex and/or the western Pacific subtropical high(WPSH).In contrast,the other two types(Q2 and Q3),which feature relatively large increases in their daily westerly components,are related to a northwest-southeast dipole pattern of pressure change due to the mid-latitude trough and the *** further analyze the considerable variations in the diurnal thermal forcing among the LLJ formation *** strong(weak)daytime heating of solar radiation leads to relatively large(small)increases in the diurnal amplitude of low-level winds in Q1 and Q2(Q3 and Q4)***,different combinations of synopticscale disturbances and diurnal thermal forcings are found to account for the diversity in LLJ formation and associated differences in downstream rainfall *** results help to improve our understanding and prediction of the formation of LLJs.

关键词： low-level jets formation processes diurnal variations synoptic-scale disturbances

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A comparison of two kinds of eastward-moving mesoscale vortices during the mei-yu period of 2010

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Science China Earth Sciences 2013年第2期56卷 282-300页

作者： FU ShenMing yu Fei WANG DongHai XIA RuDi State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences International Center for Climate and Environment Sciences Institute of Atmospheric PhysicsChinese Academy of Sciences Graduate University of Chinese Academy of Sciences

During the mei-yu period,the east edge of the Tibetan Plateau and the Dabie Mountain are two main sources of eastward-moving mesoscale vortices along the mei-yu front(MYF).In this study,an eastward-moving southwest vortex(SWV) and an eastward-moving Dabie vortex(DBV) during the mei-yu period of 2010 have been investigated to clarify the main similarities and differences between *** synoptic analyses reveal that the SWV and DBV were both located at the lower troposphere;however,the SWV developed in a "from top down" trend,whereas the DBV developed in an opposite *** were obvious surface closed low centers corresponding to the DBV during its life span,whereas for the SWV,the closed low center only appeared at the mature *** and warm air intersected intensely after the formation of both the vortices,and the cold advection in the SWV case was stronger than that in the DBV case,whereas the warm advection in the DBV case was more intense than that in the SWV *** Bay of Bengal and the South China Sea were main moisture sources for the SWV,whereas for the DBV,in addition to the above two moisture sources,the East China Sea was also an important moisture *** vorticity budget indicates that the convergence was the most important common factor conducive to the formation,development,and maintenance of the SWV and DBV,whereas the conversion from the vertical vorticity to the horizontal one(tilting) was the most important common factor caused the dissipation of both of the *** kinetic energy(KE) budget reveals that the KE generation by the rotational wind was the dominant factor for the enhancement of KE associated with the SWV,whereas for the DBV,the KE transport by the rotational wind was more important than the KE *** KE associated with the SWV and the DBV weakened with different mechanisms during the decaying ***,the characteristics of baroclinic and barotropic energy conversions during the life spans of both vor

关键词： southwest vortex mei-yu vorticity kinetic energy baroclinic energy conversion barotropic energy conversion

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Ground-Based Radar Reflectivity Mosaic of mei-yu Precipitation Systems over the Yangtze River–Huaihe River Basins

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Advances in Atmospheric Sciences 2016年第11期33卷 1285-1296页

作者： Yali LUO Weimiao QIAN yu GONG Hongyan WANG Da-Lin ZHANG State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences Beijing 100081 China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science & Technology Nanjing 210044 China Shijiazhuang Meteorological Bureau Shijiazhuang 050081 China National Meteorological Center of China Beijing 100081 China Department of Atmospheric and Oceanic Science University of Maryland College Park Collage Park Maryland 20742 USA

The 3D radar reflectivity produced by a mosaic software system, with measurements from 29 operational weather radars in the Yangtze River–Huaihe River Basins（YRHRB） during the mei-yu season of 2007, is compared to coincident TRMM PR observations in order to evaluate the value of the ground-based radar reflectivity mosaic in characterizing the 3D structures of mei-yu precipitation. Results show reasonable agreement in the composite radar reflectivity between the two datasets,with a correlation coefficient of 0.8 and a mean bias of -1 dB. The radar mosaic data at constant altitudes are reasonably consistent with the TRMM PR observations in the height range of 2–5 km, revealing essentially the same spatial distribution of radar echo and nearly identical histograms of reflectivity. However, at altitudes above 5 km, the mosaic data overestimate reflectivity and have slower decreasing rates with height compared to the TRMM PR observations. The areas of convective and stratiform precipitation, based on the mosaic reflectivity distribution at 3-km altitude, are highly correlated with the corresponding regions in the TRMM products, with correlation coefficients of 0.92 and 0.97 and mean relative differences of -7.9% and -2.5%, respectively. Finally, the usefulness of the mosaic reflectivity at 3-km altitude at 6-min intervals is illustrated using a mesoscale convective system that occurred over the YRHRB.

关键词： reflectivity Yangtze TRMM convective reasonably altitude mesoscale season Precipitation mosaic

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Anomaly of the Moist Potential Vorticity Substance with Mass Forcing and Its Application in Diagnosing mei-yu Front Rainfall

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Atmospheric and Oceanic Science Letters 2015年第1期8卷 39-44页

作者： ZHOU yu-Shu ZHU Ke-Feng ZHANG Zhe Laboratory for Cloud-Precipitation Physics and Severe Storms (LACS) Institute of Atmospheric Physics Chinese Academy of Sciences School of Atmospheric Sciences Nanjing University University of Chinese Academy of Sciences

The effects of precipitation on the moist potential vorticity substance(MPVS) are investigated by analyzing the MPVS with precipitation mass forcing and its impermeability in daily 1°× 1° data of the National Centers for Environmental Prediction/National Center for Atmospheric Research(NCEP/NCAR) over the Yangtze River Basin from 21 June to 2 July 1999. The results show that the positive MPVS anomalies appear mainly along the mei-yu front, where the maximum MPVS collocates with the maximum surface rainfall. Rain case diagnoses indicate that the MPVS anomaly may be used as a dynamical signal to detect the location and shift of the rain band when its impermeability is considered.

关键词： moist potential vorticity substance mass forcing i

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Palladium installed copper-organic framework for C–C coupling reactions

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Science China Chemistry 2025年

作者： yu-mei Wang mei-Xia Tao Kai-Ming Mo Xu Chen Shu-Hua Zhong Elena S Shubina Guo-Hong Ning Dan Li College of Chemistry and Materials Science Guangdong Provincial Key Laboratory of Supramolecular Coordination ChemistryJinan University A.N.Nesmeyanov Institute of Organoelement Compounds Russian Academy of Sciences

The formation of C–C bonds is a crucial aspect of organic synthesis. Synthesists' long-term objective is to identify novel catalysts to optimize reaction systems based on traditional transition metal catalysis. This study explores the synthesis and catalytic potential of palladium-installed covalent metal-organic frameworks(CMOFs) based on copper cyclic trinuclear units(Cu-CTUs). By incorporating palladium ions into the imine-based framework JNM-7 through a straightforward immersion method, we achieved a notable enhancement in catalytic activity for critical C–C coupling reactions, including C–H arylation and Sonogashira cross-coupling. The resulting JNM-7-Pd demonstrated remarkable stability and recyclability, maintaining its efficiency over at least three cycles without any decline in efficiency.

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Correlations of the expression of Cx43,SCF^(FBXW7),p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in colon cancer tissues

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 207-213页

作者： Rong-Gang Luan Ming-Da Liu Zi-Feng Deng Cong-Lan Lu mei-Ling yu Ming-yu Zhang Rong Liu Ran An You-Liang Yao Dong-Bei Guo Yong-Xing Zhang Lei Zhao Department of Gastrointestinal Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen 361102Fujian ProvinceChina Trauma Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina Department of Orthopaedics Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina

BACKGROUND Previous cellular studies have demonstrated that elevated expression of Cx43 promotes the degradation of cyclin E1 and inhibits cell proliferation through ***,reduced expression results in a loss of this capacity to facilitate cyclin E *** ubiquitination and degradation of cyclin E1 may be associated with phosphorylation at specific sites on the protein,with Cx43 potentially enhancing this process by facilitating the phosphorylation of these critical *** To investigate the correlation between expression of Cx43,SKP1/Cullin1/F-box(SCF)FBXW7,p-cyclin E1(ser73,thr77,thr395)and clinicopathological indexes in colon *** Expression levels of Cx43,SCF^(FBXW7),p-cyclin E1(ser73,thr77,thr395)in 38 clinical colon cancer samples were detected by immunohistochemistry and were analyzed by statistical methods to discuss their *** Positive rate of Cx43,SCF^(FBXW7),p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in detected samples were 76.32%,76.32%,65.79%,5.26%and 55.26%*** expressions of these proteins were not related to the tissue type,degree of tissue differentiation or lymph node ***43 and SCF^(FBXW7)(r=0.749),p-cyclin E1(Ser73)(r=0.667)and p-cyclin E1(Thr395)(r=0.457),SCF^(FBXW7) and p-cyclin E1(Ser73)(r=0.703)and p-cyclin E1(Thr395)(0.415)were correlated in colon cancer(P<0.05),and expressions of the above proteins were positively correlated in colon *** Cx43 may facilitate the phosphorylation of cyclin E1 at the Ser73 and Thr195 sites through its interaction with SCF^(FBXW7),thereby influencing the ubiquitination and degradation of cyclin E1.

关键词： Colon cancer Cx43 SCF^(FBXW7) Phosphorylation of cyclin E1 Sites of cyclin E1 Correlation analysis

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Machine learning model-based prediction of postpancreatectomy acute pancreatitis following pancreaticoduodenectomy:A retrospective cohort study

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World Journal of Gastroenterology 2025年第8期31卷 9-23页

作者： Ji-Ming Ma Peng-Fei Wang Liu-Qing Yang Jun-Kai Wang Jian-Ping Song yu-mei Li Yan Wen Bing-Jun Tang Xue-Dong Wang Hepatopancreatobiliary Center Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Information Administration Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Radiology Beijing Tsinghua Changgung HospitalBeijing 102218China Organ Transplantation Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina Department of Otorhinolaryngology Xiangyang No.1 People’s HospitalXiangyang 441000Hubei ProvinceChina

BACKGROUND The International Study Group of Pancreatic Surgery has established the defi-nition and grading system for postpancreatectomy acute pancreatitis(PPAP).There are no established machine learning models for predicting PPAP following pancreaticoduodenectomy(PD).AIM To explore the predictive model of PPAP,and test its predictive efficacy to guide the clinical *** Clinical data from consecutive patients who underwent PD between 2016 and 2024 were retrospectively *** analysis of PPAP risk factors was performed,various machine learning algorithms[logistic regression,random forest,gradient boosting decision tree,extreme gradient boosting,light gradient boosting machine,and category boosting(CatBoost)]were utilized to develop predictive *** feature elimination was employed to select several variables to achieve the optimal machine *** The study included 381 patients,of whom 88(23.09%)developed *** patients exhibited a significantly higher incidence of postoperative pancreatic fistula(55.68%vs 14.68%,P<0.001),grade C postoperative pancreatic fistula(9.09%vs 1.37%,P=0.001).The CatBoost algorithm outperformed other algorithms with a mean area under the receiver operating characteristic curve of 0.859[95%confidence interval(CI):0.814-0.905]in the training cohort and 0.822(95%CI:0.717-0.927)in the testing *** to shapley additive explanations analysis,pancreatic texture,main pancreatic duct diameter,body mass index,estimated blood loss,and surgery time were the most important variables based on recursive feature *** CatBoost algorithm based on selected variables demonstrated superior performance,with an area under the receiver operating characteristic curve of 0.837(95%CI:0.788-0.886)in the training cohort and 0.812(95%CI:0.697-0.927)in the testing *** We developed the first machine learning-based predictive model for PPAP following *** predictive model can assist surgeons in an

关键词： Pancreaticoduodenectomy Postoperative complication Acute pancreatitis Machine learning Predictive value

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In vivo self-assembled bispecific fluorescence probe for early detection of bladder cancer and metastasis

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Science Bulletin 2025年第3期70卷 407-418页

作者： Da-Yong Hou Ni-yuan Zhang Peng Zhang Xiang-Peng Li Jiong-Cheng Wu mei-yu Lv Zhi-Jia Wang Xing-Jie Hu Jian-Xiao Liang Hong-Lei Wang yue-Ze Wang Hui-Hui You Hong-Wei An Hao Wang Wanhai Xu NHC Key Laboratory of Molecular Probe and Targeted Theranostics Heilongjiang Key Laboratory of Scientific Research in UrologyHarbin Medical UniversityHarbin 150001China Department of PET-CT/MRI Harbin Medical University Cancer HospitalHarbin 150001China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology(NCNST)Beijing 100190China

Tumor metastasis accounts for over 90%of tumor-related deaths,prompting the development of fluorescently labeled tumor-specific molecular imaging agents for differentiating tumors from normal ***,early detection of metastasis lesions by tracking tumor markers alone has proven to be ***,we reported a glycopeptide-based bispecific fluorescence probe(bsProbe)for earlier detection of bladder cancer and *** simultaneously recognition(tumor&tumor microenvironment)and in vivo self-assembly,the tumor accumulation of bsProbe(12.3%ID/g)was obviously increased by∼6 fold compared with that in CXCR4 specific fluorescence probe(sProbe),indicating the obvious advantages of bsProbe over existing tumor metastasis detection ***,bsProbe substantially broadens the tumor diagnosis window and enhances the detection signal to noise ratio(SNR:approximately 9.5),permitting early diagnosis of lung micro-metastasis(∼1 mm),precise identifying of tumor boundaries and micro-tumors in orthotopic tumor *** importantly,bsProbe was demonstrated to distinguish malignant from benign specimen with a specificity of 90.48%and sensitivity of 92.22%in 195 clinical specimens of bladder cancer *** together,this novel synergetic targeting(CD206×CXCR4)strategy provides an attractive method for earlier detection of bladder cancer and metastasis,which might be further extended to the imaging-guided surgery of clinical invisible tumors.

关键词： Self-assembly Peptide Nanomaterial Fluorescence imaging Bladder cancer

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Clinical observation of coiling dragon needling plus chin tuck against resistance training for post-stroke deglutition disorders

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Journal of Acupuncture and Tuina Science 2025年第1期23卷 49-55页

作者： TANG Liying ZHU Lili ZHOU Ying yu mei ZHANG yuan Wenzhou TCM Hospital of Zhejiang Chinese Medical University Wenzhou 325000China

Objective:To explore the clinical efficacy of coiling dragon needling plus chin tuck against resistance(CTAR)training for post-stroke deglutition disorders and its impact on surface ***:A total of 100 patients with post-stroke deglutition disorders were randomly divided into two groups,with 50 cases in each *** groups received the same CTAR training,and the observation group was treated with additional coiling dragon *** groups were treated for 2 *** clinical efficacy,swallowing function,average value of the maximum amplitude of surface electromyography,quality of life,and the difference in adverse reactions were compared between the two ***:The total effective rate of the observation group was higher than that of the control group(P0.05).Conclusion:Compared to CTAR treatment alone,coiling dragon needling plus CTAR treatment can enhance the clinical efficacy in treating patients with

关键词： Acupuncture Therapy Coiling Dragon Needling Poststroke Syndrome Deglutition Disorders Resistance Training Surface Electromyography Randomized Controlled Trial

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