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Electrochemical determination of an anti-hyperlipidimic drug pitavastatin at electrochemical sensor based on electrochemically pre-treated polymer film modified GCE

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Journal of Pharmaceutical Analysis 2017年第4期7卷 258-264页

作者： Umar J.Pandit Gowhar A.Naikoo mehraj ud din sheikh Gulzar A.Khan K.K.Raj S.N.Limaye Department of Chemistry Dr. Harisingh Gour UniversitySagarM.P.India Department of Mathematics and Sciences College of Arts and Applied SciencesDofar UniversitySalalahOman

An electrochemically pretreated silver macroporous(Ag MP) multiwalled carbon nanotube modified glassy carbon electrode(PAN-Ag MP-MWCNT-GCE) was fabricated for the selective determination of an antihyperlipidimic drug, pitavastatin(PST). The fabricated electrochemical sensor was characterized by cyclic voltammetry(CV) and electrochemical impedance spectroscopy(EIS). The fabricated electrode was employed in quantifying and determining PST through differential pulse adsorptive stripping voltammetry(DPAdSV) and CV. The electrode fabrication proceeded with remarkable sensitivity to the determination of PST. The effect of various optimized parameters such as pH, scan rate(ν), accumulation time(t_(acc)), accumulation potential(U_(acc))and loading volumes of Ag MP-MWCNT suspension were investigated to evaluate the performance of synthesized electrochemical sensor and to propose a simple, accurate, rapid and economical procedure for the quantification of PST in pharmaceutical formulations and biological fluids. A linear response of PST concentration in the range 2.0×10^(-7)–1.6×10^(-6)M with low detection(LOD) and quantification(LOQ) limits of 9.66 ± 0.04 nM and 32.25 ± 0.07 nM, respectively, were obtained under these optimized conditions.

关键词： Pitavastatin Electrochemical sensor Adsorptive stripping voltammetry Biological fluids Pharmaceutical formulations

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Human Verification over Activity Analysis via Deep Data Mining

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Computers, Materials & Continua 2023年第4期75卷 1391-1409页

作者： Kumar Abhishek sheikh Badar ud din Tahir Senior Member IEEESeattle98103USA Department of Software Engineering Capital University of Science and Technology(CUST)Islamabad44000Pakistan

Human verification and activity analysis(HVAA)are primarily employed to observe,track,and monitor human motion patterns using redgreen-blue(RGB)images and *** human interaction using RGB images is one of the most complex machine learning tasks in recent *** models rely on various parameters,such as the detection rate,position,and direction of human body components in RGB *** paper presents robust human activity analysis for event recognition via the extraction of contextual intelligence-based *** use human interaction image sequences as input data,we first perform a few denoising ***,human-to-human analyses are employed to deliver more precise *** phase follows feature engineering techniques,including diverse feature ***,we used the graph mining method for feature optimization and AdaBoost for *** tested our proposed HVAA model on two benchmark *** testing of the proposed HVAA system exhibited a mean accuracy of 92.15%for the Sport Videos in theWild(SVW)*** second benchmark dataset,UT-interaction,had a mean accuracy of 92.83%.Therefore,these results demonstrated a better recognition rate and outperformed other novel techniques in body part tracking and event *** proposed HVAA system can be utilized in numerous real-world applications including,healthcare,surveillance,task monitoring,atomic actions,gesture and posture analysis.

关键词： AdaBoost classification deep features mining graph mining human detection human verification

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Stability analysis of a fractional-order cancer model with chaotic dynamics

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International Journal of Biomathematics 2021年第6期14卷 239-261页

作者： Parvaiz Ahmad Naik Jian Zu mehraj-ud-din Naikt School of Mathematics and Statistics Xi’an Jiaotong University Xi’anShaanxi 710049P.R.China Department of Chemical Engineering College of Engineering Jazan UniversityJazan 45142Saudi Arabia

In this paper,we develop a three-dimensional fractional-order cancer *** proposed model involves the interaction among tumor cells,healthy tissue cells and activated effector *** detailed analysis of the equilibrium points is ***,the existence and uniqueness of the solution are *** fractional derivative is considered in the Caputo *** simulations are performed to illustrate the effectiveness of the obtained theoretical *** outcome of the study reveals that the order of the fractional derivative has a significant effect on the dynamic ***,the calculated Lyapunov exponents give the existence of chaotic behavior of the proposed ***,it is observed from the obtained results that decrease in fractional-order p increases the chaotic behavior of the model.

关键词： Cancer model Caputo fractional derivative chaos stability analysis.

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Buckling Strength Analysis of Stiffened Panels of Ship Structures Using Non-linear FEM

Buckling Strength Analysis of Stiffened Panels of Ship Struc...

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作者： sheikh Ahsen-ud-din 哈尔滨工程大学

学位级别：硕士

加筋板是钢板或者铝合金板板结构中基本的强度单元。船舶和海洋结构物都是由加筋板组成的。加筋的板和壳体单元多年来一直应用于多种工程结构中。在造船工程领域中，加筋板用于船体的建造，而在航空航天领域中，加筋板用于飞机的机身和... 详细信息

加筋板是钢板或者铝合金板板结构中基本的强度单元。船舶和海洋结构物都是由加筋板组成的。加筋的板和壳体单元多年来一直应用于多种工程结构中。在造船工程领域中，加筋板用于船体的建造，而在航空航天领域中，加筋板用于飞机的机身和机翼的建造。所以加筋板的屈曲对整个结构的强度至关重要。船体结构的屈曲和极限强度近年来被广泛研究，主要通过理论分析方法，实船实验，经验公式和非线性有限元计算。理论分析方法采用第一准则并且十分精确，许多的研究已经完成。由于课题的复杂性，理论研究的办法主要处理简单的情况。由于建模和计算的耗时耗力等原因，对于设计要求来说加筋板的非线性有限元计算并不切合实际。在上一个十年中，由于计算机计算能力的提升和技术的普及，能给出特殊载荷下结构准确的力学行为且不受弹性范围的限制的非线性有限元分析变得尤为重要起来。目前研究工作旨在利用现有的有限元软件ANSYS完成对加筋板和平板结构的非线性屈曲分析，并且比较理论分析结果和线性屈曲分析结果。分析计算采用两种方法，一种是基于结构强度理论，一种是船级社的设计规范，如ABS,CSR,等等。非线性屈曲分析可以通过ANSYS软件完成。模型的生成和整个分析过程完全采用APDL （ANSYS参数化语言设计）完成。这种方法的优势在于模型的生成和分析过程更加灵活。并且在改变模型参数需要多次迭代计算的情况下能节省大量时间。分析不同的载况并且最后的结果与其他有名望的研究人的理论分析和有限元分析结构相比较，来检验分析结果的准确性。整个过程证明非线性有限元对于了解结构在不同载况下的屈曲行为非常重要。另外，开发一种新的单元初步应用于半解析有限元技术——理想结构单元法。基于理想结构单元理论，用MATLAB编写了能实现几何非线性平板分析的程序。

关键词：加筋板分析屈曲极限强度 APDL 非线性FEM

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Foliar Application of Cytokinin Modulates Gas Exchange Features,Water Relation and Biochemical Responses to Improve Growth Performance of Maize under Drought Stress

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Phyton-International Journal of Experimental Botany 2022年第3期91卷 633-649页

作者： M.Rafiqul Islam M.Shahinur Islam Nurunnaher Akter Mohammed Mohi-ud-din Mohammad Golam Mostofa Department of Agronomy Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Crop Botany Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Biochemistry and Molecular Biology Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Institute of Genomics for Crop Abiotic Stress Tolerance Department of Plant and Soil ScienceTexas Tech UniversityLubbockTX 79409USA

Improvement of plant performance under drought stress is crucial to sustaining agricultural *** current study investigated the ameliorative effects of foliar-applied kinetin,an adenine-type cytokinin(CK),on growth and gas exchange parameters,water relations and biochemical attributes of maize plants under drought ***-day-old maize plants were subjected to drought by maintaining soil moisture content at 25%field capacity for 8 days followed by foliar application of kinetin at 0,75,150 and 225 mg L^(−1)(CK0,CK75,CK150 and CK225,respectively)to the plants for two-times at the 9-day *** revealed that drought stress markedly reduced stem diameter,dry weight,chlorophyll content,gas exchange parameters and water balance but increased proline,malondialdehyde and soluble sugar contents,electrolyte leakage and senescence in maize *** of exogenous CK remarkably improved maize performance by modulating growth,gas exchange-and water relation-related parameters in a dose-dependent manner under drought ***225 increased chlorophyll content(by 61.54%),relative water content(by 49.14%),net photosynthesis rate(by 39.94%)and transpiration rate(by 121.36%)and also delayed leaf senescence but decreased internal CO_(2)concentration(by 7.38%),water saturation deficit(by 40.40%)and water uptake capacity(by 42.49%)in both well-watered and droughtstressed ***,CK application considerably decreased electrolyte leakage,proline,malondialdehyde and soluble sugar levels in drought-stressed maize plants,as also supported by heatmap and cluster *** together,exogenous CK at proper concentration(225 mg L^(−1))successfully improved maize performance under drought conditions,thereby suggesting CK application as a useful approach to alleviate drought-induced adverse effects in maize plants,and perhaps in other important crop plants.

关键词： Cytokinin drought maize osmoprotection photosynthesis water-use-efficiency

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