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Role of early transjugular intrahepatic portosystemic stent-shunt in acute variceal bleeding:An update of the evidence and future directions

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World Journal of Gastroenterology 2021年第44期27卷 7612-7624页

作者： faisal Khan Dhiraj Tripathi Gastroenterology Unit University Hospitals Birmingham NHS Foundation TrustBirmingham B152THUnited Kingdom Liver Unit University Hospitals Birmingham NHS Foundation TrustBirmingham B152THUnited Kingdom NIHR Birmingham Biomedical Research Centre University Hospitals BirminghamNHS Foundation Trust and University of BirminghamBirmingham B152THUnited Kingdom Institute of Immunology and Immunotherapy University of BirminghamBirmingham B152THUnited Kingdom

Variceal bleeding is a serious complication of cirrhosis and portal *** the improvement in management of acute variceal bleed(AVB),it still carries significant *** pressure is the main driver of variceal bleeding and also a main predictor of *** in portal pressure has been the mainstay of management of variceal *** intrahepatic porto-systemic stent shunt(TIPSS)is a very effective modality in reducing the portal hypertension and thereby,controlling portal hypertensive ***,its use in refractory bleeding(rescue/salvage TIPSS)is still associated with high mortality.“Early”use of TIPSS as a“pre-emptive strategy”in patients with AVB at high risk of failure of treatment has shown to be superior to standard treatment in several *** patients with Child C cirrhosis(up to 13 points)clearly benefit from early-TIPSS strategy,it’s role in less severe liver disease(Child B)and more severe disease(Child C>13 points)remains less ***,standard of care has improved in the last decade leading to improved 1-year survival in high-risk patients with AVB as compared to earlier“early”TIPSS *** in the real world,only a minority of patients with AVB fulfil the stringent criteria for early ***,there is unmet need to explore role of early TIPSS in management of AVB in well-designed prospective studies. In this review, we have appraised the role of early TIPSS, patient selection anddiscussed future directions in the management of patients with AVB.

关键词： Transjugular intrahepatic portosystemic stent-shunt Early transjugular intrahepatic portosystemic stent-shunt Salvage transjugular intrahepatic portosystemic stent-shunt Portal hypertension Acute variceal bleed Hepatic encephalopathy

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Early Diagnosis of Alzheimer’s Disease Based on Convolutional Neural Networks

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Computer Systems Science & Engineering 2022年第10期43卷 305-315页

作者： Atif mehmood Ahed Abugabah Ahmed Ali AlZubi Louis Sanzogni College of Technological Innovation Zayed UniversityAbu Dhabi CampusFF2-0-056UAE Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Nathan Campus Griffith UniversityBrisbaneAustralia

Alzheimer’s disease(AD)is a neurodegenerative disorder,causing the most common dementia in the elderly *** AD patients are rapidly increasing in each year and AD is sixth leading cause of death in *** resonance imaging(MRI)is the leading modality used for the diagnosis of *** learning based approaches have produced impressive results in this *** early diagnosis of AD depends on the efficient use of classification *** address this issue,this study proposes a system using two convolutional neural networks(CNN)based approaches for an early diagnosis of AD *** the proposed system,we use segmented MRI *** data samples of three classes include 110 normal control(NC),110 mild cognitive impairment(MCI)and 105 AD subjects are used in this *** data is acquired from the ADNI database and gray matter(GM)images are obtained after the segmentation of MRI subjects which are used for the classification in the proposed *** proposed approaches segregate among NC,MCI,and *** testing both methods applied on the segmented data samples,the highest performance results of the classification in terms of accuracy on NC *** are 95.33%and 89.87%,*** proposed methods distinguish between NC *** and MCI *** patients with a classification accuracy of 90.74%and 86.69%.The experimental outcomes prove that both CNN-based frameworks produced state-of-the-art accurate results for testing.

关键词： Alzheimer’s disease neural networks intelligent systems gray matter

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Simple Woods-Saxon-type form for Ωα and Ξα interactions using folding model

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Chinese Physics C 2020年第5期44卷 87-91页

作者： faisal Etminan Mohammad Mehdi Firoozabadi Department of Physics Faculty of SciencesUniversity of BirjandBirjand 97175-615Iran

We derive a simple Woods-Saxon-type form for potentials between Y=Ξ,Ωandαusing a single-folding potential method,based on a separable Y-nucleon *** PotentialsΞ+αandΩ+αare accordingly obtained using the ESC08 c Nijmegens potential(in 3 S1 channel)and HAL QCD collaborationΩN interactions(in lattice QCD),*** deriving the potential between Y andα,the same potential between Y and N is *** binding energy,scattering length,and effective range of the Y particle on the alpha particle are approximated by the resulting *** depths of the potentials inΩαandΞαsystems are obtained at-61 MeV and-24.4 MeV,*** the case of theΞαpotential,a fairly good agreement is observed between the single-folding potential method and the phenomenological potential of the Dover-Gal *** potentials can be used in 3-,4-and 5-body cluster structures ofΩandΞhypernuclei.

关键词： single-folding potential Ωα Ξα Woods-Saxon type

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Manipify:An Automated Framework for Detecting Manipulators in Twitter Trends

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Journal of Social Computing 2023年第1期4卷 46-61页

作者： Soufia Kausar Bilal Tahir Muhammad Amir mehmood Al-Khawarizmi Institute of Computer Science University of Engineering and Technology Lahore Pakistan

The rapid adoption of online social media platforms has transformed the way of communication and *** these platforms,discussions in the form of trending topics provide a glimpse of events happening around the world in ***,these trends are used for political campaigns,public awareness,and brand ***,these trends are sensitive to manipulation by malicious users who aim to mislead the mass *** this article,we identify and study the characteristics of users involved in the manipulation of Twitter trends in *** propose“Manipify”-a framework for automatic detection and analysis of malicious users in Twitter *** framework consists of three distinct modules:(1)user classifier,(2)hashtag classifier,and(3)trend *** user classifier module introduces a novel approach to automatically detect manipulators using tweet content and user behaviour ***,the module classifies human and bot ***,the hashtag classifier categorizes trending hashtags into six categories assisting in examining manipulators behaviour across different ***,the trend analyzer module examines users,hashtags,and tweets for hashtag reach,linguistic features,and user *** user classifier module achieves 0.92 and 0.98 accuracy in classifying manipulators and bots,*** further test Manipify on the dataset comprising 652 trending hashtags with 5.4 million tweets and 1.9 million *** analysis of trends reveals that the trending panel is mostly dominated by political *** addition,our results show a higher contribution of human accounts in trend manipulation as compared to bots.

关键词： trend manipulation bot classification user analysis text classification manipulator detection

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Optimization of Neutrino Oscillation Parameters Using Differential Evolution

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Communications in Theoretical Physics 2013年第3期59卷 324-330页

作者： Ghulam Mustafa faisal Akram Bilal Masud Centre for High Energy Physics University of the PunjabLahore(54590)Pakistan

We show how the traditional grid based method for finding neutrino oscillation parameters △m2 and tan2θ can be combined with an optimization technique, Differential Evolution （DE）, to get a significant decrease in computer processing time required to obtain minimal chi-square （χ2） in four different regions of the parameter space. We demonstrate efficiency for the two-neutrinos case. For this, the χ2 function for neutrino oscillations is evaluated for grids with different density of points in standard allowed regions of the parameter space of △m2 and tan2θ using experimental and theoretical total event rates of ehlorine （Homestake）, Gallex＋GNO, SAGE, Superkamiokande, and SNO detectors. We find that using DE in combination with the grid based method with smail density of points can produce the results comparable with the one obtained using high density grid, in much lesser computation time.

关键词： solar neutrinos neutrino masses and mixing numerical optimization

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Optimal Rotor Poles and Structure for Design of Consequent Pole Permanent Magnet Flux Switching Machine

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Chinese Journal of Electrical Engineering 2021年第1期7卷 118-127页

作者： Wasiq Ullah faisal Khan Muhammad Umair Department of Electrical and Computer Engineering COMSATS University Islamabad(Abbottabad Campus)Abbottabad 22040Pakistan

Permanent magnet flux switching machines(PMFSM)have attracted significant research interest and are considered as competent candidates when higher torque density is primary ***,conventional PMFSMs uses excessive rare earth PM volumes which ultimately increases machine the machine weight and PM ***,the PMs extended at the stator yoke results in stator leakage flux which degrades the *** suppress the leakage flux and diminish the PM volume,the consequent pole PMFSM(CPPMFSM)with flux bridges and barriers encompassing partitioned circumferential and radial magnetized PMs is proposed,thereby ensuring an alternate magnetic path for the working harmonics which improves the modulation effect and flux ***,the influence of the rotor pole number on seven different rotor structures namely,curved rotor,trapezoidal rotor,wide rotor tooth tip,wide rotor base width,rectangular segmented and eccentric rotors are investigated based on the electromagnetic performance and stress *** element analysis(FEA)reveals that the 12S-13P CPPMFSM with a wider rotor base offers comparatively better electromagnetic *** to the conventional PMFSM,the proposed CPPMFSM reduces the PM volume which minimizes the overall machine cost and weight,suppresses the torque ripples by 16.49%,diminishes total harmonic distortion(THD)by 35.24%and decreases cogging torque by 32.88%.Furthermore,the torque and power density are enhanced by 7.028%and 7.025%respectively.

关键词： AC Machine consequent pole flux bridge flux switching machine permanent magnet rotor pole number rotor structure stress analysis

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Laminar and Turbulent Characteristics of the Acoustic/Fluid Dynamics Interactions in a Slender Simulated Solid Rocket Motor Chamber

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Computer Modeling in Engineering & Sciences 2021年第5期127卷 437-467页

作者： Abdelkarim Hegab faisal Albatati Mohammed Algarni Department of Mechanical Engineering Faculty of Engineering at RabighKing Abdulaziz UniversityRabigh21911Saudi Arabia

In this paper,analytical,computational,and experimental studies are integrated to examine unsteady acoustic/vorticity transport phenomena in a solid rocket motor chamber with end-wall disturbance and side-wall ***-fluid dynamic interactions across the chamber may generate intense unsteady vorticity with associated shear *** stresses may cause scouring and,in turn,enhance the heat rate and erosional burning of solid propellant in a real rocket *** this modelling,the unsteady propellant gasification is mimicked by steady-state flow disturbed by end-wall *** analytical approach is formulated using an asymptotic technique to reduce the full governing *** equations that arise from the analysis possess wave properties are solved in an initial-boundary value *** numerical study is performed by solving the parabolized Navier–Stokes equations for the DNS simulation and unsteady Reynolds-averaged Navier–Stokes equations along with the energy equation using the control volume approach based on a staggered grid system with the turbulence *** v2-f turbulence model has been *** results show that an unexpectedly large amplitude of unsteady vorticity is generated at the injection side-wall of the chamber and is then penetrated downstream by the bulk motion of the internal *** stresses may cause a scouring effect and large transient heat transfer on the combustion surface.A comparison between the analytical,computational,and experimental results is performed.

关键词： Acoustic waves solid rocket motor chamber sidewall injection perturbation analysis acoustic instability turbulence models manuscript

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Does financial depth impact economic growth in North Cyprus?

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Financial Innovation 2018年第1期4卷 192-204页

作者： Turgut Türsoy faisal faisal Near East University NicosiaNorth CyprusMersin 10Turkey Institute of Business studies and leadership Faculty of Business and EconomicsAbdul Wali Khan UniversityMardanKPPakistan

This study purpose is to connect the proxy of financial development which is total banking sector’s deposits with the economic growth in North *** reason for using the total deposit differently with the existing literature is because North Cyprus is bank-based financial ***,this study provides an analysis of the connection between finance-growth nexus in North Cyprus from 1978 through 2015,using the autoregressive distributed lag(ARDL)model and combined cointegration to evaluate and verify the *** addition,this research added the inflation rate to the model specification to investigate the inflation-growth *** results revealed that both methods of cointegration provided robust evidence for a long-run relationship between financial debt and *** ARDL long-run and short-run coefficients showed the positive impact of depth and the negative impact of inflation on economic growth,thereby confirming the strength of the financegrowth and inflation-growth ***,financial depth had a larger coefficient than the inflation ***,the VECM Granger causality test provided evidence for unidirectional causality from the total deposits and inflation rate to economic growth in North *** results are significant for the policymakers of North Cyprus because the findings show that economic growth can be improved by enhancing the deposit rates in the financial system.

关键词： Financial depth Inflation rate Economic growth ARDL Granger causality

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Superplastic deformation behavior of Mg alloys: A-review

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Journal of Magnesium and Alloys 2022年第1期10卷 107-121页

作者： faisal Nazeer Jianyu Long Zhe Yang Chuan Li School of Mechanical Engineering Dong guan University of TechnologyDongguan 523808China

The magnesium alloys are the next-generation lightweight metal materials;however, the production of the complex shape components of thermo-mechanical processed magnesium alloys is very limited in comparison to their die-casted counterparts. Both high strain rate and low-temperature processing are required to save time and cost for the project. Uniaxial tensile testing has been vastly used for determining the plasticity of magnesium alloys at elevated temperatures. Therefore, this review article sheds light on superplastic behaviors under the uniaxial tensile loading of different magnesium alloys. This review also emphasizes low and high-temperature superplasticity, high strain rate superplasticity, deformation mechanism, thermal stability, texture evaluation, and fracture mechanism of extruded/rolled and severe plastic deformed magnesium alloys. At the end of the review, some technical issues have been addressed which can be beneficial for further enhancement in the superplasticity of magnesium alloys.

关键词： Superplasticity LTSP HSRSP Thermal stability Texture Fracture

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Topological evolution of laminar juncture flows under different critical parameters

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Science China(Technological Sciences) 2014年第7期57卷 1342-1351页

作者： YOUNIS Muhammad Yamin ZHANG Hua HU Bo mehmood Saqib National Key Laboratory of Fluid Mechanics School of Aeronautical Science and Engineering Beihang University School of Astronautics Beihang University

Horseshoe vortex topological structure has been studied extensively in the past,traditional"saddle of separation"and new"attachment saddle point"topologies found in literature both have theoretical basis and experimental and computational evidences for *** laminar incompressible juncture flows at low Reynolds numbers especially are observed to have new *** concerning the existence of the new topology though found in literature,the topological evolution and its dependency on various critical flow parameters require further investigation.A Particle Image Velocimetry based analysis is carried out to observe the effect of aspect ratio,?*/D and shape of the obstacle on laminar horseshoe vortex topology for small *** in aspect ratio evolves the topology from the traditional to new for all the cases *** circular cross section obstacles are found more apt to having the new topology compared to square cross *** is noted that the sweeping effect of the fluid above the vortex system in which horseshoe vortex is immersed plays a critical role in this *** evolution is observed not only in the most upstream singular point region of horseshoe vortex system but also in the corner *** corner vortex topology evolves from the traditional type to new one before the topological evolution of the most upstream singular point,resulting in a new topological pattern of the laminar juncture flows"separation-attachment combination".The study may help extend the understanding of the three-dimensional boundary layer separation phenomenon.

关键词： horseshoe vortex saddle of attachment saddle of separation topological evolution sweeping effect

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