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Coccinia grandis:Phytochemistry,pharmacology and health benefits

Clinical Traditional Medicine and Pharmacology 2024年第3期5卷 125-143页

作者： mdsabbir hossain Ishrat Jahan Mumtasin Islam Jannatun Nayeem Tahseen Sharika Anzum Nusyba Aktar Afrin Farjana Karim Mim Md.Kamrul Hasan Department of Biochemistry and Molecular Biology Tejgaon CollegeNational UniversityGazipur 1700Bangladesh Department of Public Health North South UniversityDhaka 1229Bangladesh

Background:Coccinia grandis(L.)Voigt,commonly known as Ivy gourd,is a plant of the Cucurbitaceae family that has been used in traditional medicinal systems for *** most common traditional use is managing diabetes mellitus which has been scientifically proven along with other pharmacological ***:This review aims to thoroughly explore the scientific evidence of various pharmacological activities of *** and its therapeutic ***:A thorough search of the literature was carried out to identify relevant research on *** the combination of the plants’scientific names,different keywords,such as“Coccinia grandis”“Coccinia indica”“tra-ditional medicine”“ethnobotany”“ethnomedicine”“phytochemistry”“bioactive compounds”“pharmacology”“health benefit”“side effect”“toxicity”and“clinical trial”,have been used for search using Boolean *** articles were strictly screened to maintain inclusion *** hundred and sixty-nine papers were eventually chosen for this review after a thorough examination of the retrieved articles that matched the inclusion and exclusion ***:*** was found to have a number of compounds that are biologically active and exhibit anti-diabetic,anti-dyslipidemic,anti-obesity,anti-oxidant,anti-inflammation,anti-cancer,analgesic,anti-oxidant,antinocicep-tive,antipyretic,anthelmintic,analgesic,spasmolytic,wound-healing,anti-ulcerogenic,anti-convulsant,hepato-protective and immunomodulatory activities without obvious side *** produced from the plant and different extracts of the plant show excellent anti-microbial ***:The scientific evidence encourages exploring more in-depth experimental studies regarding the phar-macological activities to develop *** as a novel therapeutic agent.

关键词： C.grandis Ivy gourd Cucurbitaceae Pharmacological activities Anti-diabetic Nanoparticles

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