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Reno-protective effect of garlic extract against immobilization stress induced changes in rats

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Asian Pacific Journal of Tropical Biomedicine 2015年第5期5卷 364-369页

作者： Syed Kashif Zaidi Shakeel Ahmed Ansari Ghulam md.Ashraf Mohammad Alam Jafri Shams tabrez Naheed Banu Center of Excellence in Genomic Medicine Research King Abdulaziz University King Fahd Medical Research Center King Abdulaziz University College of Medical Rehabilitation Qassim University

Objective: To examine immobilization stress-induced antioxidant defense alterations in rat kidney and the antioxidant effects of aqueous garlic extract in pre and post stress extract treatments. Methods: Albino rats were treated with aqueous extract of garlic both before and 6 h of immobilization stress. Pro-oxidant eminence of rat kidney was assessed by determining the levels of glutathione, thiobarbituric acid reactive substances, aspartate aminotransferase, alanine aminotransferase, glucose, uric acid, alkaline phosphatase and antioxidant enzymes activities. Results: In response to 6 h of immobilization stress, a significant rise in the level of kidney enzymes was recorded. However, antioxidant enzyme activities showed a sharp decline. Conclusions: The extract treatment before and after the stress reverted the activities of above mentioned enzymes towards their control values. Hence, garlic extract can be given as nutritional supplement for scavenging the free radicals generated in rat kidney.

关键词： Stress Antioxidant enzymes AST ALT mdA Garlic

Features Desired in Public Transport in a Developing City: Users’ Perspective

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Journal of Transportation Technologies 2023年第4期13卷 632-643页

作者： md. nafis Imtiyaz md. Golam Sobhani Mostafiz Emtiaz Arcadis US Inc. Houston USA Ardaman and Associates Inc. St. Rose USA RRP Consulting Engineers LLC Houston USA

Excessive growth of population and urbanization in the developing countries set an increasing demand of mobility services. To meet this demand, public transport plays a significant role by providing an easy and affordable mobility service. Public transport service is a process evolving over time nevertheless is not always directly responsive to the changing demand of the passengers. Recently in developing countries, the unpleasant experience in public transport services is seen as one of the main reasons behind increased passenger car share, which eventually lead to traffic congestion. However, the situation can be ameliorated if the features of the public transport are improved by addressing the users’ demand. In this study, the primary features desired and demanded by the passengers of a developing country are identified by three phase survey. These identified features are also categorized based on public responses. And finally, the required features in an appropriate public transport mode are prioritized by using a common Multi Criteria Decision Making approach (AHP—Analytic Hierarchy Process). The study suggests that residents of the developing city are not that much concern on the outlook and ambience of the service rather they are concerned about finishing their trips safely in time at an affordable rate. The findings of this research will help planners and decision makers to make the best use of the investment in public transport services and infrastructure to promote these modes over privately owned vehicle.

关键词： Public Transport Feature Analytical Hierarchy Process (AHP) Questionnaire Respondents Weightage

Characterization of Coal Spoil Recovered from Coal Mine Drainage Water

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Journal of Geoscience and Environment Protection 2017年第11期5卷 227-236页

作者： Aninda nafis Ahmed md. Anwar Arfien Khan Madhu Sudan Saha Sharmin Sultana Pilot Plant and Process Development Centre (PP & PDC) BCSIR Dhaka Bangladesh Leather Research Institute (LRI) BCSIR Savar Dhaka Bangladesh Institute of Mining Mineralogy and Metallurgy (IMMM) BCSIR Joypurhat Bangladesh

Barapukuria Coal Mine situated in the district Dinajpur. Bangladesh is playing an important role in the economy of this country by the mining of top quality coal. With coal mining, mine waste is also generated called coal spoil. Coal spoil can impose environmental threat if not treated carefully. In contrast, it can also be converted to value added product. In the present work, coal spoils collected from Barapukuria coal mine drainage water were investigated to determine the quality of the samples by physico-chemical analysis (proximate and ultimate analysis) as well as by heating value determination. 50% of carbon was detected in the samples after elemental analysis, with sulfur content less than 0.4%. Calorific value around 9300 btu/lb was obtained for the coal spoil. Moreover, moisture content, ash, volatile matter content and fixed carbon also provided fruitful information regarding the quality and economic prospect of the samples in comparison to the quality of Barapukuria coal.

关键词： Coal Spoil Calorific Value XRF XRD Particle Size Analysis Thermal Analysis

Status of Renal and Liver Function in Rheumatoid Arthritis (RA) Patients of Chattogram, Bangladesh Treated with Methotrexate (MTX)

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Journal of Biosciences and Medicines 2023年第9期11卷 114-126页

作者： Mohammad Razuanul Hoque md. Abdur Razzaque Abrar nafis Mohammad Shahriar Zawad Sharaf Wasima Rahman Department of Biochemistry and Molecular Biology University of Chittagong Chattogram Bangladesh Department of Rheumatology Chittagong Medical College Hospital Chattogram Bangladesh

Rheumatoid Arthritis (RA) is a chronic autoimmune disorder that is usually manifested as inflammation in multiple joints and several extra-articular symptoms, involving the liver, kidney, eye, skin, blood, blood vessels, heart, lungs, nervous system, and other organs. Methotrexate (MTX) is the anchor drug that treats RA. As renal and liver abnormalities are more common during disease conditions as well as during the treatment period, we tried to find out if there is any impact of MTX in these organs during the treatment of RA patients. Once the disease complications are developed, it is quite difficult to reverse the disease, and treatment in this situation is not very effective. Consequently, patients suffer a lot. So, early evaluation of renal and liver function is essential for the treatment of RA patients and it might also help prevent different complications which are usually very frequently observed. This was a cross-sectional study. A total of 150 RA patients treated with MTX were evaluated for the study where female and male respondents were 115 and 35 respectively. In this study, we found that 82% of RA patients had creatinine levels ≤ 1.1 mg/dL although the normal range of serum creatinine is below 1.4 mg/dL. Usually, a 15% increase in Serum creatinine level from the baseline is considered renal impairment. We found 4% of such cases. Moreover, 2% of RA patients had creatinine levels above the normal range of 1.4 mg/dL and those patients were hypertensive as well. So, a total (4 + 2 = 6)% had renal impairments. Among them, 5% had diabetes mellitus. On the other hand, the ultrasonogram (USG) of RA patients with kidney disease showed signs of renal parenchymal disease and 3% of RA patients having renal problems whose serum creatinine level was within the normal range showed signs of chronic kidney disease (CKD). On the other hand, 2% of RA patients showed signs of hepatic parenchymal disease. In this study, 69% of RA patients had ALT levels ≤ 50 mg/dL, 23% ha

关键词： Rheumatoid Arthritis Renal Function Liver Function C-Reactive Protein Methotrexate