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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 50-52页

作者： Mamun-Al Mahtab Salimur Rahman Mobin Khan md.fazal karim Department of Hepatology Bangabandhu Sheikh Mujib Medical University

BACKGROUND:Acute-on-chronic liver failure(ACLF) is common in *** viral E hepatitis is sporadically encountered in this country each year,with a rising incidence in the rainy *** study aimed to identify the etiology of ACLF in Bangladesh. METHODS:In this retrospective study,69 ACLF patients were *** presented to our department at the Bangabandhu Sheikh Mujib Medical University in *** of diseases was recorded and appropriate investigations were conducted in all patients. RESULTS:Acute hepatitis E virus(HEV)infection was positive in 21.7%(15/69)of the patients,while 14.5% (10/69)had *** gastrointestinal tract hemorrhage was seen in 4.3%of the patients(3/69),while another 4.3%(3/69)had a positive history for alcohol or *** of the patients tested positive for hepatitis A virus infection and no evidence of hepatitis B virus flare was found in any *** specific cause for ACLF could be identified. CONCLUSIONS:Acute HEV infection is a leading cause of ACLF in *** patients were thought to have decompensation of cirrhosis,but subsequently were recognized as having ACLF by a retrospective review according to the definition of the Asian Pacific Association for the Study of the Liver Working Party Meeting on ACLF in New Delhi in early 2008.

关键词： acute-on-chronic liver failure hepatitis E virus septicemia

Epidemiology of hepatitis B virus in Bangladeshi general population

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Hepatobiliary & Pancreatic Diseases International 2008年第6期7卷 595-600页

作者： Mamun-Al Mahtab Salimur Rahman md.fazal karim Mobin Khan Graham Foster Susannah Solaiman Shahrin Afroz Department of Hepatology Bangabandhu Sheikh Mujib Medical University Digestive Diseases Research Centre Bart's and the London Queen Mary's School of Medicine and Dentistry Department of Gastroenterology Bangabandhu Sheikh Mujib Medical University

BACKGROUND:Hepatitis B virus(HBV)is encountered sporadically the year round in *** results in a wide range of liver diseases,with asymptomatic acute hepatitis at one end to hepatocellular carcinoma(HCC)at the other end of the spectrum. METHODS:All 1018 individuals of different age groups and sex with varied religious,educational and social backgrounds were tested for HBsAg by *** positive samples were further tested by ELISA for *** testing,blood samples were preserved at-20℃.The study was conducted in a semi-urban location on the outskirts of Dhaka. RESULTS:Of the 1018 individuals,5.5%tested positive for *** were tested positive for *** the HBsAg-positive population,58.93%were HBeAg- positive and the rest 41.07%*** was a male predominance and those who were tested positive were mostly between 16 and 50 years of *** risk factors for exposure to HBV appeared to be injudicious use of injectable medications,treatment by unqualified, traditional practitioners,mass-vaccination against cholera and smallpox,barbers and body piercing. CONCLUSION:HBV remains a major cause of morbidity and mortality in Bangladesh and we have a long way to go before we may bid farewell to this deadly menace.

关键词： hepatitis B virus prevalence general population Banglandesh

Thornthwaite moisture index and depth of suction change under current and future climate‒An Australian study

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1761-1775页

作者： md Rajibul karim Bikash Devkota md Mizanur Rahman Hoang Bao Khoi Nguyen UniSA STEM University of South AustraliaMawson Lakes CampusMawson LakesSouth Australia5095Australia

Climate change is one of the major global challenges and it can have a significant influence on the behaviour and resilience of geotechnical *** changes in moisture content in soil lead to effective stress changes and can be accompanied by significant volume changes in reactive/expansive *** volume change leads to ground movement and can exert additional stresses on structures founded on or within a shallow depth of such *** change is likely to amplify the ground movement potential and the associated problems are likely to *** effect of atmospheric boundary interaction on soil behaviour has often been correlated to Thornthwaite moisture index(TMI).In this study,the long-term weather data and anticipated future projections for various emission scenarios were used to generate a series of TMI maps for *** changes in TMI were then correlated to the depth of suction change(H s),an important input in ground movement *** all climate scenarios considered,reductions in TMI and increases in H s values were observed.A hypothetical design scenario of a footing on expansive soil under current and future climate is *** is observed that a design that might be considered adequate under the current climate scenario,may fail under future scenarios and accommodations should be made in the design for such events.

关键词： Climate change Future prediction Thornthwaite moisture index(TMI) Characteristic surface movement Infrastructure resilience

An Enhanced Hybrid Model Based on CNN and BiLSTM for Identifying Individuals via Handwriting Analysis

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1689-1710页

作者： md.Abdur Rahim Fahmid Al Farid Abu Saleh Musa Miah Arpa Kar Puza md.Nur Alam md.Najmul Hossain Sarina Mansor Hezerul Abdul karim Department of Computer Science and Engineering Pabna University of Science and TechnologyPabna6600Bangladesh Faculty of Engineering Multimedia UniversityCyberjaya63100Malaysia Department of Computer Science and Engineering Bangladesh Army University of Science and TechnologySaidpur5311Bangladesh Department of Mathematics Pabna University of Science and TechnologyPabna6600Bangladesh Department of Electrical Electronic and Communication EngineeringPabnaUniversity of Science and TechnologyPabna6600Bangladesh Department of Electrical and Communication Engineering Pabna University of Science and TechnologyPabna6600Bangladesh

Handwriting is a unique and significant human feature that distinguishes them from one *** are many researchers have endeavored to develop writing recognition systems utilizing specific signatures or symbols for person identification through ***,such systems are susceptible to forgery,posing security *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** innovative method is intricately designed,encompassing five distinct phases:data collection,preprocessing,feature extraction,significant feature selection,and *** key advancement lies in the creation of a novel dataset specifically tailored for Bengali handwriting(BHW),setting the foundation for our comprehensive ***-preprocessing,we embarked on an exhaustive feature extraction process,encompassing integration with kinematic,statistical,spatial,and composite *** meticulous amalgamation resulted in a robust set of 91 *** enhance the efficiency of our system,we employed an analysis of variance(ANOVA)F test and mutual information scores approach,meticulously selecting the most pertinent *** the identification phase,we harnessed the power of cutting-edge deep learning models,notably the Convolutional Neural Network(CNN)and Bidirectional Long Short-Term Memory(BiLSTM).These models underwent rigorous training and testing to accurately discern individuals based on their handwriting ***,our methodology introduces a groundbreaking hybrid model that synergizes CNN and BiLSTM,capitalizing on fine motor features for enhanced individual ***,our experimental results unde

关键词： Bengali handwriting(BHW) person identification convolutional neural network(CNN) BiLSTM

Heat and Mass Transfer on Non-Newtonian Peristaltic Flow in a Channel in Presence of Magnetic Field: Analytical and Numerical Analysis

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Applied Mathematics 2024年第8期15卷 568-583页

作者： md. Maruf Hasan md. Enamul karim md. Abdus Samad Department of Mathematics Comilla University Comilla Bangladesh Department of Applied Mathematics University of Dhaka Dhaka Bangladesh

A study has been arranged to investigate the flow of non-Newtonian fluid in a vertical asymmetrical channel using peristalsis. The porous medium allows the electrically conductive fluid to flow in the channel, while a uniform magnetic field is applied perpendicular to the flow direction. The analysis takes into account the combined influence of heat and mass transfer, including the effects of Soret and Dufour. The flow’s non-Newtonian behavior is characterized using a Casson rheological model. The fluid flow equations are examined within a wave frame of reference that has a wave velocity. The analytic solution is examined using long wavelengths and a small Reynolds number assumption. The stream function, temperature, concentration and heat transfer coefficient expressions are derived. The bvp4c function from MATLAB has been used to numerically solve the transformed equations. The flow characteristics have been analyzed using graphs to demonstrate the impacts of different parameters.

关键词： Stream Function Mass Transfer Vertical Channel Casson Fluid

Risk Factors Categorizations of Ischemic Heart Disease in South-Western Bangladesh

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Data Intelligence 2024年第3期6卷 834-868页

作者： M.Raihan Sami Azam Laboni Akter md.Mehedi Hassan Ryana Quadir Asif karim Saikat Mondal Arun More Department of Computer Science and Engineering North Western UniversityKhulna 9100Bangladesh Faculty of Science and Technology Charles Darwin UniversityNT 0909Australia Departmentof Biomedical Engineering Khulna University of Engineering&TechnologyKhulnaBangladeh Computer Science and Engineering Discipline Khulna UniversityKhulna 9208Bangladesh Department of Computer Science and Engineering Daffodil International University(DIU)Bangladesh Department of Cardiology Ter Institute of Rural Health and ResearchMurud-413510India

Ischemic heart disease(IHD)is one of the leading causes of death ***,different geographic regions show different variations of the risk factors of this disease based on the different lifestyles of *** study examines the current IHD condition in southern Bangladesh,a Southeast Asian middle-income *** main approach to this research is an Al-based proposal of a reduced set of the greatest impact clinical traits that may cause *** approach attempts to reduce IHD morbidity and mortality by early detection of risk factors using the reduced set of clinical ***,diagnostic,and symptomatic features were considered for analysing this clinical *** pre-processing utilizes several machine learning techniques to select significant features and make meaningful interpretations.A proposed voting mechanism ranked the selected 138 features by their impact *** this regard,diverse patterns in correlations with variables,including age,sex,career,family history,obesity,etc.,were calculated and explained in terms of voting *** the 138 risk factors,three labels were categorized:high-risk,medium-risk,and low-risk features;19 features were regarded as high,25 were medium,and 94 were considered low impactful *** research's technological methodology and practical goals provide an innovative and resilient framework for addressing IHD,especially in less developed cities and townships of Bangladesh,where the general population's socioeconomic conditions are often *** data collection,pre-processing,and use of this study's complete and comprehensive IHD patient dataset is another innovative *** believe that other relevant research initiatives will benefit from this work.

关键词： Ischemic heart disease Machine learning CVD Data categorization Medical data

Cumulative Air Quality Impacts from Twenty-Two Major Power Plants

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Journal of Environmental Science and Engineering(A) 2024年第1期13卷 1-14页

作者： md M.karim Navin Bindra Arub Masud Environment Health and Safety DepartmentGEEC Ltd.108 Earlsbridge Blvd.BramptonOntarioL7A 3W7Canada Department of Health Science University of WaterlooWaterlooOntarioN2L 3G1Canada

Cumulative assessment is a tool for the project developer to try and take into consideration not only their contribution to cumulative impacts but also other projects and external factors that may place their developments at *** study assessed the cumulative impacts of air emissions from 22 major power plants in southeast Bangladesh planned to generate 21,550 MW of *** also includes anticipated growth in small to medium size industries,brickfields,highway traffic,inland water transport,transhippers,jetty,and vessel transports used for transporting fuel resources for these power plants.A 50 km by 50 km airshed is considered for air quality *** analysis indicates that predicted MGLCs(Maximum Ground Level Concentrations)of NO2 and CO are complying with both Bangladesh NAAQS(National Ambient Air Quality Standards)and WBG(World Bank Group)*** daily average MGLC of PM_(2.5)(62.45µg/m^(3))from all sources complies with NAAQS,however,exceeds the WBG *** PM_(2.5) concentration(15.45µg/m^(3))exceeds NAAQS and WBG *** PM10 concentration complies with the NAAQS for both 24-hour and annual averaging *** average concentration(23.12µg/m^(3))exceeds WBG *** average SO2 concentration(102.49µg/m^(3))complies with the NAAQS however,it exceeds the WBG guideline *** concentrations of PM_(2.5) and SO2 are due to the contribution of transboundary emissions and secondary pollutants in the *** dispersion modeling outcome can be used by the policymakers for the pollution reduction strategy.

关键词： CIA(Cumulative Impact Assessment) dispersion modeling power generation Bangladesh.

Coccinia grandis:Phytochemistry,pharmacology and health benefits

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Clinical Traditional Medicine and Pharmacology 2024年第3期5卷 125-143页

作者： mdSabbir Hossain Ishrat Jahan Mumtasin Islam Jannatun Nayeem Tahseen Sharika Anzum Nusyba Aktar Afrin Farjana karim Mim md.Kamrul Hasan Department of Biochemistry and Molecular Biology Tejgaon CollegeNational UniversityGazipur 1700Bangladesh Department of Public Health North South UniversityDhaka 1229Bangladesh

Background:Coccinia grandis(L.)Voigt,commonly known as Ivy gourd,is a plant of the Cucurbitaceae family that has been used in traditional medicinal systems for *** most common traditional use is managing diabetes mellitus which has been scientifically proven along with other pharmacological ***:This review aims to thoroughly explore the scientific evidence of various pharmacological activities of *** and its therapeutic ***:A thorough search of the literature was carried out to identify relevant research on *** the combination of the plants’scientific names,different keywords,such as“Coccinia grandis”“Coccinia indica”“tra-ditional medicine”“ethnobotany”“ethnomedicine”“phytochemistry”“bioactive compounds”“pharmacology”“health benefit”“side effect”“toxicity”and“clinical trial”,have been used for search using Boolean *** articles were strictly screened to maintain inclusion *** hundred and sixty-nine papers were eventually chosen for this review after a thorough examination of the retrieved articles that matched the inclusion and exclusion ***:*** was found to have a number of compounds that are biologically active and exhibit anti-diabetic,anti-dyslipidemic,anti-obesity,anti-oxidant,anti-inflammation,anti-cancer,analgesic,anti-oxidant,antinocicep-tive,antipyretic,anthelmintic,analgesic,spasmolytic,wound-healing,anti-ulcerogenic,anti-convulsant,hepato-protective and immunomodulatory activities without obvious side *** produced from the plant and different extracts of the plant show excellent anti-microbial ***:The scientific evidence encourages exploring more in-depth experimental studies regarding the phar-macological activities to develop *** as a novel therapeutic agent.

关键词： C.grandis Ivy gourd Cucurbitaceae Pharmacological activities Anti-diabetic Nanoparticles

Autophagy as a targeted therapeutic approach for skin cancer:Evaluating natural and synthetic molecular interventions

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Cancer Pathogenesis and Therapy 2024年第4期2卷 231-245页

作者： md.Liakot Ali Amdad Hossain Roky S.M.Asadul karim Azad Abdul Halim Shaikat Jannatul Naima Meem Emtiajul Hoque Abu Mohammed Fuad Ahasan Mohammed Murshedul Islam md.Saifur Rahaman Arif md.Saqline Mostaq md.Zihad Mahmud Mohammad Nurul Amin mdAshiq Mahmud Department of Pharmacy University of ChittagongChattogram 4331Bangladesh Pratyasha Health Biomedical Research Center Dhaka 1230Bangladesh Department of Pharmacy International Islamic University ChittagongChattogram 4318Bangladesh Department of Pharmacy Daffodil International UniversityDhaka 1216Bangladesh Department of Pharmacy BGC Trust University BangladeshChattogram 4381Bangladesh School of Basic Pharmaceutical and Toxicological Sciences College of PharmacyUniversity of Louisiana at MonroeMonroeLA 71209-0497USA Pioneer Dental College and Hospital Dhaka 1229Bangladesh

Skin cancer,a prevalent malignancy worldwide,poses significant health concerns owing to its increasing ***,a natural cellular process,is a pivotal event in skin cancer and has advantageous and detrimental *** duality has prompted extensive investigations into medical interventions targeting autophagy modulation for their substantial therapeutic *** systematic review aimed to investigate the relationship between skin cancer and autophagy and the contribution and mechanism of autophagy modulators in skin *** outlined the effectiveness and safety of targeting autophagy as a promising therapeutic strategy for the treatment of skin *** comprehensive review identified a diverse array of autophagy modulators with promising potential for the treatment of skin *** of these compounds demonstrates efficacy through distinct physiological mechanisms that have been elucidated in ***,findings from a literature search indicated that none of the natural,synthetic,or semisynthetic compounds exhibited notable adverse effects in either human or animal ***,this review offers novel mechanistic and therapeutic perspectives on the targeted modulation of autophagy in skin cancer.

关键词： Autophagy Skin cancer Autophagy inducers Autophagy inhibitors Nature-derived compounds Synthetic compounds

Viral load speaks little about toll on liver

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Hepatobiliary & Pancreatic Diseases International 2007年第5期6卷 483-486页

作者： Mamun-Al Mahtab Salimur Rahman Mobin Khan md Kamal Ayub Al Mamun md.fazal karim Department of Hepatology Bangabandhu Sheikh Mujib Medical University DhakaBangladesh Department of Pathology Bangabandhu Sheikh Mujib Medical University DhakaBangladesh

BACKGROUND:Bangladesh is situated in the intermediate prevalence region of hepatitis B virus (HBV).The lifetime risk of acquiring HBV infection in Bangladesh is greater than 40%.It has been estimated that this virus is responsible for 10%-35%cases of acute viral hepatitis,35.7%cases of fulminant hepatic failure, 33.3%-40.5%cases of chronic hepatitis and 46.8%cases of hepatocellular carcinoma in *** aim of this study is to compare the correlation between HBV DNA load and grade and stage of liver disease in patients with chronic hepatitis B(CHB). METHODS:Percutaneous liver biopsies done in 159 CHB patients revealed 62.9%(100 patients)had wild type HBV infection and the rest 37.1%(59)had pre-core/core promoter mutant HBV *** DNA load was measured using PCR in all patients. RESULTS:In the wild type CHB group,97%(97 patients) had moderate to high HBV DNA load and 3%(3)had low to moderate HBV *** the pre-core/core promoter mutant group,74.6%(44 patients)had moderate to high HBV DNA and the rest 25.4%(15)had low to moderate HBV *** patients with moderate to high HBV DNA of the patients with wild type CHB,78.4%(76 patients) had minimal to mild chronic hepatitis(HAI-NI 0-8)and 21.6%(21)had moderate to severe chronic hepatitis(HAI- NI 9-18).66.6%(2 patients)and 33.3%(1)patients with low to moderate HBV DNA load had minimal to mild and moderate to severe chronic hepatitis *** the moderate to high HBV DNA group,77.3%(75 patients) patients had minimal to moderate fibrosis(HAI-F 0-2)and 22.7%(22)(HAI-F 3-4)had severe fibrosis to *** figures were 33.3%(1 patient)and 66.6% (2)respectively in the patients with low to moderate HBV DNA *** the other hand in case of patients with pre-core/core promoter mutant type CHB,in the moderate to high HBV DNA group,79.5%(35 patients)had minimal to mild chronic hepatitis(HAI-NI 0-8)and 20.5%(9)had moderate to severe chronic hepatitis(HAI-NI 9-18).93.3% (14)and 6.7%(1)patients with low to mod

关键词： HBV DNA chronic hepatitis B hepatic necro-inflammation hepatic fibrosis