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Autophagy in neuroinflammation after traumatic brain injury

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Neural Regeneration Research 2024年第5期19卷 951-952页

作者： Chinmoy sarkar Marta M.Lipinski Shock Trauma and Anesthesiology Research(STAR)CenterDepartment of AnesthesiologyUniversity of Maryland School of MedicineBaltimoreMDUSA Department of Anatomy and Neurobiology University of Maryland School of MedicineBaltimoreMDUSA

Traumatic brain injury(TBI)is an acquired injury of the brain caused by the impact of external forces on the brain(Maas et al.,2008).It is a major cause of death and disability among people of all ages(Maas et al.,2008).The primary mechanical injury to the brain initiates a cascade of secondary biochemical events that lead to acute and chronic neurodegeneration and activation of inflammatory pathways(Maas et al.,2008).Both brain-resident microglia and blood-derived myeloid cells-macrophages and monocytes that infiltrate the brain due to injury-induced blood-brain barrier damage,contribute to the inflammatory responses after TBI(Morganti et al.,2015).

关键词： damage death after

Designing an Effective Method for Automatic Electric Vehicle Charging Stations in a Static Environment

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Journal of Power and Energy Engineering 2024年第1期12卷 15-28页

作者： md. Robiul Islam Maisha Islam Tania sarkar Hanif Mia md. Asadullah Department of Electrical Engineering Hohai University Nanjing China Institute of Science Trade & Technology (ISTT) Dhaka Bangladesh

This article outlines an Effective Method for Automatic Electric Vehicle Charging Stations in a Static Environment. It consists of investigated wireless transformer structures with various ferrite forms. WPT technology has rapidly advanced in the last few years. At kilowatt power levels, the transmission distance grows from a few millimeters to several hundred millimeters with a grid to load efficiency greater than 90%. The improvements have made the WPT more appealing for electric vehicle (EV) charging applications in both static and dynamic charging scenarios. Static and dynamic WEVCS, two of the main applications, are described, and current developments with features from research facilities, academic institutions, and businesses are noted. Additionally, forthcoming concepts based WEVCS are analyzed and examined, including “dynamic” wireless charging systems (WCS). A dynamic wireless power transfer (DWPT) system, which can supply electricity to moving EVs, is one of the feasible alternatives. The moving secondary coil is part of the dynamic WPT system, which also comprises of many fixed groundside (primary) coils. An equivalent circuit between the stationary system and the dynamic WPT system that results from the stationary system is demonstrated by theoretical investigations. The dynamic WPT system’s solenoid coils outperform circular coils in terms of flux distribution and misalignment. The WPT-related EV wireless charging technologies were examined in this study. WPT can assist EVs in overcoming their restrictions on cost, range, and charging time.

关键词： Dynamic Wireless Power Transfer (DWPT) Wireless Charging System (WCS) Electric Vehicle (EV) Dynamic Performance

Post Thyroidectomy Assessment of Intact Parathyroid Hormone for Early Prediction of Hypocalcaemia

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第2期13卷 71-84页

作者： md. Masum Billah Ripon Kumar sarkar md. Yousuf Ali Saad Zaman md. Nazmul Hasan md. Shehab Uddin md. Mosleh Uddin Kazi Shameemus Salam Farzana Binte Abedin Leera Department of Otolaryngology-Head & Neck Surgery Universal Medical College Hospital Dhaka Bangladesh Department of Otolaryngology-Head & Neck Surgery National Institute of Ear Nose and Throat Dhaka Bangladesh Shaheed Ahsan Ullah Master General Hospital Gazipur Bangladesh Department of Otolaryngology-Head & Neck Surgery Cumilla Medical College Cumilla Bangladesh Department of ENT Oncology National Institute of Cancer Research & Hospital Dhaka Bangladesh Department of ENT Outdoor Rajshahi Medical College Hospital Rajshahi Bangladesh Department of Otolaryngology-Head & Neck Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Biochemistry Delta Medical College Hospital Dhaka Bangladesh

Background: As the half-life of intact parathyroid hormone (iPTH) is very low, it reflects parathyroid insufficiency within minutes to hours after total thyroidectomy. Therefore, iPTH level assessment in the postoperative period can be used to predict the development of hypocalcaemia. The optimal time point to measure serum iPTH is important for the accurate prediction of hypocalcaemia. Aim: This paper aims to evaluate the ability of iPTH as an early predictive marker of hypocalcaemia and determine which time iPTH is more able to predict postoperative hypocalcaemia. Method: This prospective observational study was conducted in the Department of Otolaryngology-Head & Neck Surgery, BSMMU, Dhaka, from July 2020 to December 2021, with 67 patients who underwent total thyroidectomy. iPTH levels were measured on the day before the operation and at 1 hour, 4 hours, and 24 hours after the operation. *** levels were measured on the day before the operation and 1st postoperative day. All the data were compiled and sorted properly and were analyzed statistically. Results: Postoperative hypocalcaemia developed in 18 cases, with an incidence of 26.9%. Pearson correlation showed a significant correlation between postoperative iPTH at 1 hr, 4 h, and 24 hr with 1st postoperative calcium value. The Receiver operating characteristic (ROC) curve was processed for the postoperative iPTH at 1 hr, 4 h, and 24 hr. The sensitivity, specificity, cut-off value, and mean AUC found 93.9%, 94.4%, ≤14.0, 0.988;95.9%, 94.4%, ≤09.5, 0.993 and 91.8%, 94.4%, ≤11.0, 0.993 respectively. Conclusion: iPTH can be used as an early predictor of post-thy-roidectomy hypocalcaemia. 4 hr iPTH showed more sensitivity and specificity for a cut-off value near the laboratory reference range.

关键词： Total Thyroidectomy Hypocalcaemia Serum Intact Parathyroid Hormone Early Predictor of Hypocalcaemia

Optimization of process parameters for the bioconversion of activated sludge by Penicillium corylophilum, using response surface methodology

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Journal of Environmental Sciences 2007年第1期19卷 23-28页

作者： sarkar Mannan Ahmadun Fakhru'l-Razi md Zahangir Alam Department of Chemical and Environmental Engineering Faculty of Engineering University Putra Malaysia (UPM)43400 UPM SerdangSelangorD.E.Malaysia. Department of Biotechnology Engineering Faculty of Engineering International Islamic University Malaysia (IIUM)Jalan Gombak53100 Kuala LumpurMalaysia.

The optimization of process parameters for the bioconversion of activated sludge by Penicillium corylophilum was investigated using response surface methodology （RSM）. The three parameters namely temperature of 33℃, agitation of 150 r/min, and pH of 5 were chosen as center point from the previous study of fungal treatment. The experimental data on chemical oxygen demand （COD） removal （%） were fitted into a quadratic polynomial model using multiple regression analysis. The optimum process conditions were determined by analyzing response surface three-dimensional surface plot and contour plot and by solving the regression model equation with Design Expert software. Box-Behnken design technique under RSM was used to optimize their interactions, which showed that an incubation temperature of 32.5℃, agitation of 105 r/min, and pH of 5.5 were the best conditions. Under these conditions, the maximum predicted yield of COD removal was 98.43%. These optimum conditions were used to evaluate the trail experiment, and the maximum yield of COD removal was recorded as 98.5%.

关键词： optimization response surface methodology Penicillium activated sludge domestic wastewater sludge

Efficient removal of heavy metals from electroplating wastewater using polymer ligands

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Frontiers of Environmental Science & Engineering 2016年第2期10卷 352-361页

作者： md. Lutfor RAHMAN Shaheen M. sarkar Mashitah Mohd YUSOFF Faculty of Industrial Sciences & Technology Universiti Malaysia Pahang 26300 Gambang Kuantan Malaysia

Poly（hydroxamic acid）-poly（amidoxime） che- lating ligands were synthesized from poly（methyl acrylate-co-acrylonitrile） grafted acacia cellulose for removing toxic metal ions from industrial wastewaters. These ligands showed higher adsorption capacity to copper （2.80 mmol. g-l） at pH 6. In addition, sorption capacities to other metal ions such as iron, zinc, chromium, and nickel were also found high at pH 6. The metal ions sorption rate （tl/2） was very fast. The rate of adsorption of copper, iron, zinc, chromium, nickel, cobalt, cadmium and lead were 4, 5, 7, 5, 5, 8, 9 and 11 min, respectively. Therefore, these ligands have an advantage to the metal ions removal using the column technique. We have successfully investigated the known concentration of metal ions using various parameters, which is essential for designing a fixed bed column with ligands. The wastewater from electroplating plants used in this study, having chromium, zinc, nickel, copper and iron, etc. For chromium wastewater, ICP analysis showed that the Cr removal was 99.8% and other metal ions such as Cu, Ni, Fe, Zn, Cd, Pb, Co and Mn removal were 94.7%, 99.2%, 99.9%, 99.9%, 99.5%, 99.9%, 95.6% and 97.6%, respectively. In case of cyanide wastewater, the metal removal, especially Ni and Zn removal were 96.5 and 95.2% at higher initial concentra- tion. For acid/alkali wastewater, metal ions removing for Cd, Cr and Fe were 99.2%, 99.5% and 99.9%, respectively. Overall, these ligands are useful for metal removal by column method from industrial wastewater especially plating wastewater.

关键词： heavy metals adsorption wastewater chelat-ing ligands plating industry

Two New Records of Snapper(Perciformes, Lutjanidae) from Saint Martin's Island, Bangladesh

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Journal of Ocean University of China 2021年第2期20卷 439-444页

作者： sarkar Provakar ISLAM md Jayedul HABIB AHMShafiullah NEOGI Amit Kumer HABIB Kazi Ahsan Department of Zoology Jagannath UniversityDhaka 1100Bangladesh Aquatic Bioresource Research Laboratory Department of Fisheries Biology and GeneticsSher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh Department of Fisheries Biology and Genetics Faculty of FisheriesAquaculture and Marine ScienceSher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh

The present work documented two snapper species, Lutjanus fulvus Forster, 1801 and Lutjanus erythropterus Bloch, 1790, recently collected from the Saint Martin's Island, Bay of Bengal, Bangladesh, during a survey on coral associated fishes of Bangladesh from July 2017 to September 2018. These two species were identified with morphological characteristics and by analyzing partial mitochondrial COI sequences. The document also included an updated checklist of snappers available in Bangladesh.

关键词： Lutjanus fulvus Lutjanus erythropterus DNA barcoding Bay of Bengal

Synthesis and photoswitching properties of azobenzene liquid crystals with a pentafluorobenzene terminal

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Chinese Chemical Letters 2014年第12期25卷 1611-1614页

作者： md Lutfor Rahman Gurumuthy Hegde Shaheen M.sarkar Mashitah Mohd Yusoff Faculty of Industrial Sciences  Technology Universiti Malaysia PahangKuantan 26300Malaysia

The fluorine-substituted benzoate ester rod-shaped liquid crystals containing an azobenzene side chain linked with terminal double bonds were synthesized and *** mesophase and photoswitching properties were determined by polarizing optical microscopy（POM）,differential scanning calorimetry（DSC） and UV-visible *** rod-shaped compound 4a having an odd number of carbon atoms in the alkyl chains exhibits nematic phase and SmA type phase whereas compound 4b having an even number of carbon atoms showed only nematic *** fluorinecontaining compounds 4c and 4d showed only SmA type *** photoswitching properties of these compounds showed a rate of trans to cis isomerization ranging 19-20 s,whereas reverse process took around 230 min in *** materials may be ideal in the field of optically rewritable applications where both on and off rates should be crucial.

关键词： Liquid crystals Azobenzene Photoswitching Fluorine compounds

Experimental evaluation of asphalt mixtures with emerging additives against cracking and moisture damage

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Journal of Road Engineering 2023年第4期3卷 336-349页

作者： md.Tanvir A.sarkar Mostafa A.Elseifi Department of Civil and Environmental Engineering Louisiana State UniversityBaton RougeLA 70803USA

The objective of this study was to evaluate and recommend an asphalt mixture design with emerging additive technologies that would provide superior performance against asphalt concrete(AC)stripping and *** achieve this objective,a laboratory test program was developed to evaluate the use of nanomaterials(nanoclay and graphene nanoplatelet),an emerging anti-stripping agent(adhere),and warm-mix asphalt technologies(ZycoTherm,Sasobit,and EvoTherm).Two mix types were evaluated,which were a stone-matrix asphalt(SMA)and a dense-graded binder *** addition,the modified Lottman test(AASHTO T 283)and the indirect tensile asphalt cracking test(IDEAL-CT)test were used as performance indicators of moisture damage resistance and cracking *** were analyzed statistically to identify and quantify the effects of the design variables and selected additives on the performance,moisture damage resistance,and durability of asphalt *** on the cracking test results,a superior cracking resistance performance was observed with ZycoTherm,irrespective of the mix *** had the lowest average cracking indices for both mix types,which suggest that it would not perform as well as the other additives in terms of cracking ***,SMA mixes displayed greater cracking resistance than the dense-graded mixtures,which may have been the result of the reclaimed asphalt pavement(RAP)material used in the dense-graded mix and its lower asphalt binder *** terms of moisture resistance,both nanomaterials(graphene nanoplatelet and nanoclay)did not perform well as they did not meet the minimum required tensile strength ratio(TSR)criterion(>0.80).In addition,nanomaterials showed the lowest TSR values in both mix types suggesting that their effectiveness against moisture-induced damage may not be as good as warm-mix *** the other hand,warm-mix additives were expected to show enhanced performance in terms of moisture resistance as compared to the o

关键词： Pavement Asphalt concrete Moisture damage Cracking Laboratory testing Nanomaterials

Kenaf cellulose-based poly(amidoxime) ligand for adsorption of rare earth ions

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Rare Metals 2019年第3期38卷 259-269页

作者： md Lutfor Rahman Mohd Sani Sarjadi Sazmal Effendi Arshad Mashitah M. Yusoff Shaheen M. sarkar Baba Musta Faculty of Science and Natural Resources Universiti Malaysia Sabah Faculty of Industrial Sciences and Technology University Malaysia Pahang

A well-known adsorbent, poly(amidoxime)ligand, was prepared from polyacrylonitrile(PAN) grafted kenaf cellulose, and subsequent characterization was performed by Fourier transform infrared spectroscopy(FTIR),field emission scanning electron microscope(FESEM) and inductively coupled plasma mass spectrometry(ICP-MS).The adsorption capacities of the prepared ligand for rare earth metals are found to be excellent, with adsorptions of La^(3+), Ce^(3+), Pr^(3+), Gd^(3+) and Nd^(3+) experimentally determined to be 262, 255, 244, 241 and 233 mg·g^(-1), respectively, at pH 6. The experimental values of the adsorption of rare earth metals are well matched with the pseudosecond-order rate equation. The reusability of the adsorbent is examined for seven cycles of sorption/desorption,demonstrating that the proposed adsorbent could be reused for over seven cycles without any significant loss in the original removal capability of the ligand.

关键词： Adsorption Poly(amidoxime) Rare earths Separation Kenaf cellulose