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Tackling global health security by building an academic community for One Health action

Infectious Diseases of Poverty 2023年第4期12卷 93-98页

作者： Xiao-Xi Zhang Xin-Chen Li Qi-Yu Zhang Jing-Shu Liu Le-Fei Han Zohar Lederman Janna M.Schurer Patrícia Poeta md.Tanvir rahman Shi-Zhu Li Kokouvi Kassegne Kun Yin Yong-Zhang Zhu Shang Xia Lu He Qin-Qin Hu Le-Shan Xiu Jing-Bo Xue Han-Qing Zhao Xi-Han Wangv Logan Wu Xiao-Kui Guo Zhao-Jun Wang Bernhard Schwartländer Ming-Hui Ren Xiao-Nong Zhou School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China Institute of One Health Shanghai Jiao Tong UniversityShanghaiPeople’s Republic of China Medical Ethics and Humanities Unit Hong Kong UniversityHong KongPeople’s Republic of China Center for One Health University of Global Health EquityButaroRwanda Microbiology and Antibiotic Resistance Team Department of Veterinary SciencesUniversity of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Green Chemistry Chemistry DepartmentUniversity Nova of LisbonLisbonPortugal Veterinary and Animal Research Centre University of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Animal and Veterinary Sciences University of Trás-os-Montes and Alto DouroVila RealPortugal Department of Microbiology and Hygiene Bangladesh Agricultural UniversityMymensinghBangladesh National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghaiPeople’s Republic of China Walter and Eliza Hall Institute ParkvilleAustralia Department of Medical Biology University of MelbourneMelbourneAustralia German Ministry of Foreign Affairs(Former Assistant Director General and Chef de Cabinet of Dr Tedros at the World Health Organization) BerlinGermany School of Public Health Peking UniversityBeijingPeople’s Republic of China

Background One Health approach is crucial to tackling complex global public health threats at the interface of humans, animals, and the environment. As outlined in the One Health Joint Plan of Action, the international One Health community includes stakeholders from different sectors. Supported by the Bill & Melinda Gates Foundation, an academic community for One Health action has been proposed with the aim of promoting the understanding and real-world implementation of One Health approach and contribution towards the Sustainable Development Goals for a healthy *** text The proposed academic community would contribute to generating high-quality scientific evidence, distilling local experiences as well as fostering an interconnected One Health culture and mindset, among various stakeholders on different levels and in all sectors. The major scope of the community covers One Health governance, zoonotic diseases, food security, antimicrobial resistance, and climate change along with the research agenda to be developed. The academic community will be supported by two committees, including a strategic consultancy committee and a scientific steering committee, composed of influential scientists selected from the One Health information database. A workplan containing activities under six objectives is proposed to provide research support, strengthen local capacity, and enhance global *** The proposed academic community for One Health action is a crucial step towards enhancing communication, coordination, collaboration, and capacity building for the implementation of One Health. By bringing eminent global experts together, the academic community possesses the potential to generate scientific evidence and provide advice to local governments and international organizations, enabling the pursuit of common goals, collaborative policies, and solutions to misaligned interests.

关键词： One Health Global health Academic community

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南亚国家对中国“一带一路”倡议的看法

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中国周边外交学刊 2016年第1期 63-78页

作者：穆希伯·拉赫曼陈妙玲孟加拉共和国国家战略研究所复旦大学中国与周边国家关系研究中心

本文重点关注印度、孟加拉和斯里兰卡对中国＂21世纪海上丝绸之路＂倡议（MSR,简称＂海丝路＂）做出的回应。对于从古至今与中国有着密切往来的南亚地区而言,这一倡议已产生重大的影响。尽管将＂海丝路＂视为海上往来沟通的桥梁已经是... 详细信息

本文重点关注印度、孟加拉和斯里兰卡对中国＂21世纪海上丝绸之路＂倡议（MSR,简称＂海丝路＂）做出的回应。对于从古至今与中国有着密切往来的南亚地区而言,这一倡议已产生重大的影响。尽管将＂海丝路＂视为海上往来沟通的桥梁已经是一个普遍的共识,但南亚国家在落实具体决策时仍旧面临外交和政策困境。虽然经济的相互依存、基础建设发展的需求以及国家经济向海洋定位的方向为中国与南亚国家创造了大量合作互补的可能性,但小国所要承担的地缘和外交压力以及国内政治共识的缺乏,使它们很难对中国的倡议做出有效的回应。尤其是孟加拉和斯里兰卡一直在努力寻求以一种务实平衡的方式加入丝绸之路倡议。与此相比,印度仍然对中国＂海丝路＂倡议的长远动机存疑,并采取模糊立场。尽管认识到＂海丝路＂倡议有符合印度重要经济利益的潜力,但印度对中国崛起的地缘政治担忧以及对中国在印度洋日益增强的影响力的不安,使＂海丝路＂在印度的发展充满坎坷。

关键词：南亚印度斯里兰卡孟加拉国 “一带一路”

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Rapid Detection of Wheat Blast Pathogen Magnaporthe oryzae Triticum Pathotype Using Genome-Specific Primers and Cas12a-mediated Technology

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Engineering 2021年第9期7卷 1326-1335页

作者： Houxiang Kang Ye Peng Kangyu Hua Yufei Deng Maria Bellizzi Dipali Rani Gupta Nur Uddin Mahmud Alfredo S.Urashima Sanjoy Kumar Paul Gary Peterson Yilin Zhou Xueping Zhou md.Tofazzal Islam Guo-Liang Wang State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Department of Plant Pathology The Ohio State UniversityColumbusOH 43210USA Institute of Biotechnology and Genetic Engineering(IBGE) Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityDhaka 1706Bangladesh Centro de Ciências Agrárias Universidade Federal de São CarlosArarasSP CEP 13600-000Brazil Foreign Disease-Weed Science Research Unit(FDWSRU) United States Department of Agriculture-Agricultural Research Service(USDA-ARS)Ft.DetrickMD 21702USA

Wheat blast,caused by the fungus Magnaporthe oryzae Triticum(MoT)pathotype,is a devastating disease persistent in South America and *** MoT generally fails to cause visual symptoms in wheat until the heading stage when the infection would have advanced,disease control by fungicide application solely based on the detection of visual symptoms is *** develop an accurate and sensitive method to detect MoT at the seedling and vegetative stages for disease control,we sequenced the genomes of two MoT isolates from Brazil and identified two DNA fragments,MoT-6098 and MoT-6099,that are present in the MoT genome but not in the genome of the rice-infecting Magnaporthe oryzae Oryzae(MoO)*** polymerase chain reaction(PCR),we confirmed the specificity of the two markers in 53 MoT and MoO isolates from South America and *** test the efficiency of the two markers,we first established a loop-mediated isothermal amplification(LAMP)method to detect MoT at isothermal conditions,without the use of a PCR *** this,we used the Cas12a protein and guide RNAs(gRNAs)to target the MoT-6098 and MoT-6099 *** activated Cas12a showed indiscriminate single-stranded deoxyribonuclease(ssDNase)*** then combined targetdependent Cas12a ssDNase activation with recombinase polymerase amplification(RPA)and nucleic acid lateral flow immunoassay(NALFIA)to develop a method that accurately,sensitively,and cost-effectively detects MoT-specific DNA sequences in infected wheat *** novel technique can be easily adapted for the rapid detection of wheat blast and other important plant diseases in the field.

关键词： Wheat blast Magnaporthe oryzae Triticum Cas12a Nucleic acid rapid lateral flow immunoassay Field detection

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Effect of Microwave Power and Clamping Pressure on the Microwave Welding of Polypropylene Using Silicon Carbide Nanowhiskers as Microwave Susceptor

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Chinese Journal of Polymer Science 2022年第11期40卷 1466-1481页

作者： Phey Yee Foong Chun Hong Voon Bee Ying Lim Pei Leng Teh Mohd Afendi Bin Rojan Nor Azizah Parmin Subash C.B.Gopinath Mohd Khairuddin md.Arshad Foo Wah Low Savisha Mahalingam Abreeza Manap Ruslinda A.Rahim Uda Hashim Institute of Nano Electronic Engineering Universiti Malaysia PerlisSeriabKangarPerlis01000Malaysia Faculty of Chemical Engineering Technology Universiti Malaysia PerlisJejawiPerlis Arau02600Malaysia Faculty of Mechanical Engineering Technology Universiti Malaysia PerlisPauhPerlis Arau02600Malaysia Department of Electrical&Electronic Engineering Lee Kong Chian Faculty of Engineering&ScienceUniversiti Tunku Abdul RahmanBandar Sungai LongKajangSelangor43000Malaysia Institute of Sustainable Energy Universiti Tenaga NasionalJalan IKRAM-UNITENKajangSelangor43000Malaysia

Due to their excellent dielectric properties and the rapid response to microwave irradiation,silicon carbide nanowhiskers(SiCNWs)were employed as microwave susceptor in this study to absorb microwave and locally melt the surrounding polypropylene(PP)substrates for the joining of PP *** welded joint is formed after the melted PP was cooled and *** than microwave susceptor,SiCNWs also acted as the nanofillers in strengthening the welded joint through the formation of SiCNWs reinforced PP nanocomposite at the interface of PP ***,the effect of microwave power on the microwave welding of PP substrates using SiCNWs as susceptor was studied and *** was found that the tensile strength and modulus of elasticity of the welded joint improved as microwave power ***,it deteriorates the flexibility of the welded joint as high stiffness SiCNWs were incorporated deeper into the PP matrix which restricted the PP chain *** from microwave power,clamping pressure is also critical in determining the mechanical properties of a welded *** compared to unclamped welded joint,the tensile strength,modulus of elasticity and flexibility of welded joint subjected to clamping pressure improved ***,the tensile strength of welded joint increased when the clamping pressure was increased from P1 to P3,but decreased when the clamping pressure was further increased to P4 due to the occurrence of flashing at welded *** formation mechanism of SiCNWs reinforced PP welded joint was also proposed in this *** to conventional welding,this welding process is easy,straightforward and is able to produce welded joint with outstanding mechanical properties via precise controlling of the processing ***,microwave welding is thought to offer an option for the joining of thermoplastics and other applications.

关键词： Microwave welding Silicon carbide Nanowhiskers Joining Susceptor

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Tribo-Mechanical and Electrochemical Properties of Carbonitrided 316 Austenitic Stainless Steel by rf Plasma for Biomedical Applications

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Advances in Materials Physics and Chemistry 2018年第9期8卷 358-377页

作者： F. M. El-Hossary M. Raaif A. M. Abd El-rahman M. Abo EL-Kassem Physics Department Faculty of Science Sohag University Sohag Egypt

AISI 316 austenitic stainless steel was carbonitrided using rf plasma with purpose of using low-cost orthopedic implant materials in biomedical applications besides the manufacturing requests. The plasma treatment process was accomplished at low working gas pressure of 0.075 mbar in nitrogen-acetylene gaseous mixture. The plasma-processing time was fixed at 10 min while the plasma-processing power was varied from 450 to 650 watt. The effect of plasma treatment power on the structure, tribological, mechanical, electrochemical and biocompatibility of AISI 316 has been investigated. The structural results demonstrated the formation of nitrogen and carbon solid solutions, chromium nitride, iron carbide and iron nitride phases in the treated samples. The microhardness of the treated layer increases with increasing the processing power to reach a maximum value of approximately 1300 HV0.1 at 600 W which represents more than 6-folds increase in microhardness in comparison with the untreated matrix. The wear and corrosion resistance of the treated AISI 316 were enhanced compared to the untreated one. The friction coefficient was reduced from nearly 0.5 for the untreated substrate to nearly 0.3 for the carbonitrided sample. The surface energy and wettability of the carbonitrided samples were augmented as the plasma-processing power increased. Furthermore, the numbers of grown mesenchymal stem cells are higher for carbonitrided samples compared to the untreated one. The formation of nitrogen and carbon solid solution, chromium nitride, iron nitride and iron carbide hard phases after carbonitriding process is responsible for achieving good mechanical, tribological, biocompatibility and electrochemical properties for AISI 316 alloys.

关键词： Plasma-Material Interactions 52.40.Hf Surface Hardening 81.65.Lp Mechanical Properties 62.20.Qp Surface Energy 68.35.md Biocompatibility 87.85.Jj

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Blossoming Characteristics in Black Cumin Genotypes in Relation Seed Yield Influenced by Sowing Time

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American Journal of Plant Sciences 2015年第8期6卷 1167-1183页

作者： md.Ziaul Haq M. Mofazzal Hossain M. Moynul Haque Mira Rani Das Muhammad Shamsul Huda Seed Science and Technology Unit Bangabandhu Sheikh Mujibur Rahman Agricultural University Gazipur Bangladesh Department of Horticulture Bangabandhu Sheikh Mujibur Rahman Agricultural University Gazipur Bangladesh Agriculture Training Institute Gazipur Bangladesh Scientific Officer Farm Division Bangladesh Agricultural Research Institute Joydebpur Gazipur Bangladesh

Black cumin (Nigella sativa L.;Family-Ranunculaceae) is an important spice crop. Mature seeds are consumed for edible and medical purposes and also used as a food additive and flavour. Seed of black cumin has great potentiality as spice crop due to nutritive and medicinal values. The experiments were carried out at Bangabandhu Sheikh Mujibur rahman Agricultural University, Gazipur during 2011 to 2012 to determine optimum planting time for seed production of black cumin. The experiment was two factorials. Factor A: 4 genotypes were V1: Exotic, Iran;V2: BARI kalozira-1;V3: Local, Faridpur and V4: Local, Natore. Factor B: sowing date: D1: 16 October;D2: 1 November;D3: 16 November and D4: 1 December. Therefore, treatment combinations were 16 in total. So, in 3 replications total plot was 48. Result revealed that significantly the highest 2.37 t/ha in V1, followed by V2 (1.96 t/ha). V2 and V3 (1.97 t/ha) were statistically similar and maximum yield was obtained from D2 (2.65 t/ha). In combined effect, maximum yield 3.00 t/ha was obtained in V1D2.. Investigation on time of sowing revealed that performance of black cumin was better in earlier sowings (16 October, 1 November) than later ones. The highest yield (4g plant-1;2.65 tha-1) was obtained when the crop was sown on 1 November. Among the genotypes, the exotic one with sowing in 1 November gave the highest seed yield (4.54 g·plant-1;3.00 t·ha-1).

关键词： Black Cumin Flower Blooming Capsule Seed Yield Sowing Time

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Towards an actionable One Health approach

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Infectious Diseases of Poverty 2024年第2期13卷 77-82页

作者： Xiao-Xi Zhang Zohar Lederman Le-Fei Han Janna M.Schurer Li-Hua Xiao Zhi-Bing Zhang Qiu-Lan Chen Dirk Pfeiffer Michael P.Ward Banchob Sripa Sarah Gabriël Kuldeep Dhama Krishna Prasad Acharya Lucy J.Robertson Sharon L.Deem Cécile Aenishaenslin Filipe Dantas-Torres Domenico Otranto Delia Grace Yang Wang Peng Li Chao Fu Patrícia Poeta md.Tanvir rahman Kokouvi Kassegne Yong-Zhang Zhu Kun Yin Jiming Liu Zhao-Jun Wang Xiao-Kui Guo Wen-Feng Gong Bernhard Schwartländer Ming-Hui Ren Xiao-Nong Zhou School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China Institute of One Health Shanghai Jiao Tong UniversityShanghaiPeople’s Republic of China Medical Ethics and Humanities Unit Hong Kong UniversityHong KongPeople’s Republic of China Center for One Health University of Global Health EquityButaroRwanda College of Veterinary Medicine South China Agricultural UniversityGuangzhouPeople’s Republic of China School of Ecology and Environment Hainan UniversityHaikouHainanPeople’s Republic of China Branch of animal and vector-borne diseases Division of Infectious Disease ControlChinese Center for Disease Control and PreventionBeijingPeople’s Republic of China Centre for Applied One Health Research and Policy Advice Department of Infectious Diseases and Public HealthJockey Club College of Veterinary Medicine and Life SciencesCity University of Hong KongHong Kong SARPeople’s Republic of China Department of Pathobiology and Population Sciences Royal Veterinary CollegeLondonUnited Kingdom Sydney School of Veterinary Science The University of SydneyCamdenAustralia Tropical Disease Research Center Department of Tropical MedicineFaculty of MedicineKhon Kaen UniversityKhon KaenThailand Laboratory of foodborne parasitic zoonoses Department of translational physiologyinfectiology and public healthChair Faculty Committee on InternationalisationFaculty of Veterinary MedicineGhent UniversityMerelbekeBelgium Division of Pathology ICAR-Indian Veterinary Research Institute(IVRI)BareillyUttar PradeshIndia Department of Livestock Services Animal Quarantine Office-KathmanduBudhanilkanthaKathmanduNepal Parasitology Department of Paraclinical SciencesFaculty of Veterinary MedicineNorwegian University of Life SciencesÅsNorway One Government Drive Saint Louis Zoo Institute for Conservation MedicineSt.LouisUSA Groupe de Recherche enÉpidémiologie des Zoonoses et SantéPublique(GREZOSP) Facultéde médecine v

Background Despite the increasing focus on strengthening One Health capacity building on global level,challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific *** these gaps,the One Health Action Commission(OHAC)was established as an academic community for One Health action with an emphasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of,and motivation for,the recently formed *** the urgent need for evidence to support the formulation of necessary action plans,OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses,antimicrobial resistance,addressing food safety,and to enhance capacity building for context-sensitive One Health *** By promoting broader engagement and connection of multidisciplinary stakeholders,OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge,distilled practical experience and actionable policy advice,guided by strong ethical principles of One Health.

关键词： One Health Global Health One Health Action Commission Research agenda

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利用基因组特异性引物和Cas12a介导技术快速检测稻瘟菌小麦致病型

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Engineering 2021年第9期7卷 279-299页

作者：康厚祥彭烨 Kangyu Hua 邓雨飞 Maria Bellizzi Dipali Rani Gupta Nur Uddin Mahmud Alfredo S.Urashima Sanjoy Kumar Paul Gary Peterson 周益林周雪平 md.Tofazzal Islam 王国梁 State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural Sciences Department of Plant Pathology The Ohio State University Institute of Biotechnology and Genetic Engineering (IBGE) Bangabandhu Sheikh Mujibur Rahman Agricultural University Centro de Ciências Agrárias Universidade Federal de S?o Carlos Foreign Disease-Weed Science Research Unit (FDWSRU) United States Department of Agriculture-Agricultural Research Service (USDA-ARS)

麦瘟病由稻瘟菌小麦致病型（MoT）引起，是一种存在于南美洲和孟加拉国的毁灭性病害。由于MoT通常不会在抽穗期之前使小麦显现染病症状，但在抽穗期其侵染会一直加剧，因此仅根据肉眼观察来使用杀菌剂是无效的。为了开发一种在苗期和营... 详细信息

麦瘟病由稻瘟菌小麦致病型（MoT）引起，是一种存在于南美洲和孟加拉国的毁灭性病害。由于MoT通常不会在抽穗期之前使小麦显现染病症状，但在抽穗期其侵染会一直加剧，因此仅根据肉眼观察来使用杀菌剂是无效的。为了开发一种在苗期和营养期准确、灵敏检测MoT以控制病害蔓延的方法，我们对来自巴西的两个MoT分离株的基因组进行了测序，并确定了两个DNA片段：MoT-6098和MoT-6099，它们存在于麦瘟病菌（MoT）基因组中，但不存在于感染稻瘟病菌（MoO）的水稻基因组中。利用聚合酶链反应（PCR），我们在来自南美洲和孟加拉国的53株MoT和MoO分离株中证实了这两对标记引物的特异性。为了测试这两对标记引物的有效性，我们首先建立了一种环介导等温扩增（LAMP）方法。在等温条件下，这种方法在不使用常规PCR仪器的情况下也能检测MoT。随后，我们使用Cas12a蛋白及导向RNA(g RNAs)靶向MoT-6098和MoT-6099序列，两个靶标被识别后，均能激活Cas12a非特异切割单链脱氧核糖核酸酶（ss DNAase）的活性，我们将依赖靶向Cas12a激活ss DNase活性，同时将重组酶聚合酶扩增（RPA）和核酸侧流免疫分析法（NALFIA）相结合，开发出一种准确、灵敏且经济高效地检测受感染小麦植株中MoT特异性DNA序列的方法。这种新技术可应用于田间麦瘟病和其他重要植物病害的快速检测。

关键词：麦瘟病稻瘟菌小麦致病型 Cas12a 核酸侧流免疫分析田间检测

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