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Performance Evaluation of a miniPET Camera for Brain Scanning

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2015年第1期4卷 71-75页

作者： Arif Mahmud md. moshiur rahman Department of Physics BGMEA University of Fashion and Technology Dhaka Bangladesh Department of Physics Jahangirnagar University Dhaka Bangladesh

A nuclear miniPET camera was constructed with 2 bucket rings, each having 8 BGO detector modules for brain scanning. After calibration of the camera, an experimental investigation of sensitivity was carried out to evaluate the performance of this PET scanner. The characteristics of NECR were examined for comparisons of count rate considering the statistical noise due to scattered and random events. NECR performance was observed using 10 cm diameter phantom filled with 1 L water and 240 MBq of 18F. All data were acquired in 2D acquisition mode but without septa. Randoms were estimated by introducing delay into the coincidence circuit which was an extra 100 ns time delay. Multiples were recorded simultaneously with the prompt and delayed events. The true plus scattered coincidence events were calculated as the difference between prompt and random plus multiple events. After recording all the data, the noise equivalent count rate (NECR) was calculated and graphically presented. It is observed that NEC value is significantly lower than other similar scanners. Comparing the individual components of the count rate, a much higher randoms rate is observed for the camera because of the absence of any side shielding, so that out of field activity contributes significantly to the randoms rate and hence reduces the NECR value.

关键词： PET BGO NECR Prompt-Events Detector-Module & Septa

Factors Affecting Children’s Cholesterol Levels with a View to Prevent Cardiovascular Disease—The Unique Benefits of Health Screening at the Elementary School

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Health 2017年第1期9卷 172-188页

作者： Akihiro Kihara Hiromi Kawasaki Satoko Yamasaki Mika Nishiyama md. moshiur rahman Graduate School of Biomedical & Health Sciences Hiroshima University Hiroshima Japan Institute of Biomedical & Health Sciences Hiroshima University Hiroshima Japan Department of Welfare Hiroshima Bunkyo Women’s University Hiroshima Japan

Background: The prevention of cardiovascular disease (CVD) can substantially contribute to reducing the mortality rate across countries. The level of interest in cholesterol among experts increases when the subjects are elderly and obese individuals. However, specialists do not recommend that children should receive the cholesterol test. The objective of this study was to investigate the distribution of cholesterol levels among the children of public school and their parents’ lifestyles that are associated with cholesterol levels, and to assess the need for and utility of cholesterol testing in school settings. Methods: The study investigated a group of 226 fourth-grade public school children aged between 9 and 10 years and guardians in Akitakatacity of Hiroshima Prefecture, Japan. Multiple regression analyses were performed with the logarithmic value of cholesterol levels as a response variable, awareness about lifestyles and health of children as an explanatory variable, and child’s sex and body mass index (BMI) as moderating variables. Using questionnaires about lifestyles, the step-down procedure was applied in multiple regression analyses to narrow down relevant lifestyle variables. Results: The percentage of children with the high total cholesterol (TC) value was about 15 and with low-density lipoprotein (LDL) cholesterol value was about 10. Children with low high-density lipoprotein (HDL) cholesterol value were 5%. Treatment was not required according to the comprehensive assessment. Cholesterol levels were associated with the situation of the children and their guardians as follows, guardian need to consider the food, and child has the correct knowledge about food like how to eat snacks. Conclusions: Children had poor cholesterol levels. From childhood, along with the parents, there is a need to learn about appropriate level of cholesterol for CVD prevention.

关键词： Children’s Lifestyle-Related Disease Cardiovascular Disease Health Promotion for Family School Health

Outcome of Long Segment Transpedicular Screw Fixation in Unstable Thoracolumbar Spine Injury with Incomplete Neurological Deficit

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Journal of Biosciences and Medicines 2020年第3期8卷 166-187页

作者： Shah md. Rezaul Karim A. K. M. Shahidur rahman Syed Abdus Sobhan md. Shahidul Islam Akon Muhammad Akter Hossain Ashraf Ali Shah Newas md. Ruhul Quddus md. moshiur rahman Mollick Department of Surgery Sheikh Hasina Medical College Hospital Habiganj Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Orthopaedic Surgery Dhaka Medical College Hospital (DMCH) Dhaka Bangladesh Department of Anatomy Chandpur Medical College Chandpur Bangladesh Department of Cardiology Abdul Malek Ukil Medical College Hospital Noakhali Bangladesh Department of Orthopaedic Surgery National Institute of Traumatology and Orthopedic Rehabilitation (NITOR) Dhaka Bangladesh Department of Biochemistry Pabna Medical College Pabna Bangladesh Department of Orthopaedic Surgery Sheikh Hasina Medical College Hospital Habiganj Bangladesh

Background: Long segment transpedicular screw fixation in thoracolumbar spine injury has gained popularity in the last decades as it provides immediate stability, prevents further risk of complications and allows early mobilization of patient. Objectives: Evaluation of clinical and functional outcome after long segment transpedicular screw fixation in unstable thoracolumbar spine injury with incomplete neurological deficit patients. Methods: This quasi experimental study was conducted at Dhaka Medical College and Hospital (DMCH), Dhaka, Bangladesh from January 2016 to December 2017. A total of twenty four (24) patients with traumatic unstable fracture of the thoracolumbar spine with incomplete neurological deficit underwent long segment transpedicular screw fixation were included in this study. Clinical and radiologic outcomes were assessed pre-operatively and post-operatively. Results: A total of 24 patients aged between 20 - 60 years of both sexes (Male-21, Female-03) were included in this study. Their mean (±SD) age was 33.12 (±8.57) years. Most of them were farmer [09 (37.5%)] and day labour [08 (33.33%)]. Motor vehicle accidents were the most common [16 (66.67%)] cause of injury and then fall from height [08 (33.33%)]. The most common level of injury involved was L1-10 (41.67%) patients, followed by L2-07 (29.17%), T12-05 (20.83%) and T11-02 (8.33%) of the study patients. Burst fracture was the commonest [22 (91.67%)] type of fracture followed by Chance fracture [02 (8.33%)]. Pre-operative mean (±SD) Cobb angle, Kyphotic deformation of vertebral body, Beck index and vertebral compression deformity were 21.83 ± 4.5 degrees, 22.09 ± 4.40 degrees, 0.78 ± 2.65 and 0.18 ± 0.93 mm respectively, after procedure which were significantly (p Conclusions: Long segment transpedicular screw fixation is an effective method of treatment in patients having thoracolumbar spine injury with incomplete neurological deficit.

关键词： Neurological Deficit Transpedicular Screw Fixation Unstable Thoracolumbar Spine Injury

The link between intracellular calcium signaling and exosomal PD-L1 in cancer progression and immunotherapy

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Genes & Diseases 2024年第1期11卷 321-334页

作者： md.Rakibul Alam md.Mizanur rahman Zhiguo Li Department of Toxicology and Cancer Biology College of MedicineUniversity of KentuckyLexingtonKY 40506USA Department of Medicine(Nephrology) Faculty of Medicine and DentistryUniversity of AlbertaEdmontonAlberta T6E2H7Canada

Exosomes are small membrane vesicles containing microRNA,RNA,DNA fragments,and proteins that are transferred from donor cells to recipient *** cells release exo-somes to reprogram the factors associated with the tumor microenvironment(TME)causing tu-mor metastasis and immune *** evidence revealed that cancer cell-derived exosomes carry immune inhibitory molecule program death ligand 1(PD-L1)that binds with re-ceptor program death protein 1(PD-1)and promote tumor progression by escaping immune ***,some FDA-approved monoclonal antibodies are clinicallyused for cancer treatment by blocking PD-1/PD-L1 *** notable treatment outcomes,some pa-tients show poor drug *** PD-L1 plays a vital role in lowering the treatment response,showing resistance to PD-1/PD-L1 blockage therapy through recapitulating the ef-fect of cell surface *** enhance therapeutic response,inhibition of exosomal PD-L1 is *** signaling is the central regulator of tumorigenesis and can regulate exosome biogenesis and secretion by modulating Rab GTPase family and membrane fusion ***-mune checkpoints are also connected with calcium signaling and calcium channel blockers like amlodipine,nifedipine,lercanidipine,diltiazem,and verapamil were also reported to suppress cellular PD-L1 ***,to enhance the PD-1/PD-L1 blockage therapy response,the reduction of exosomal PD-L1 secretion from cancer cells is in our therapeutic *** this review,we proposed a therapeutic strategy by targeting calcium signaling to inhibit the expression of PD-L1-containing exosome levels that could reduce the anti-PD-1/PD-L1 therapy resistance and increase the patient's drug response rate.

关键词： Calcium signaling CD8^(+)T cells Exosomal PD-L1 Exosomes biogenesis Immunosuppression Immunotherapy

Adequate Closed Form Wave Solutions to the Generalized KdV Equation in Mathematical Physics

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Journal of Applied Mathematics and Physics 2024年第6期12卷 2069-2082页

作者： md. Munnu Miah md. Al Amin Meia md. Matiur rahman Sarker Ahammodullah Hasan Department of Mathematics Islamic University Kushtia Bangladesh Department of Mathematics Government Titumir College Dhaka Bangladesh Department of Pharmacy University of Asia Pacific Dhaka Bangladesh

In this paper, we consider the generalized Korteweg-de-Vries (KdV) equations which are remarkable models of the water waves mechanics, the shallow water waves, the quantum mechanics, the ion acoustic waves in plasma, the electro-hydro-dynamical model for local electric field, signal processing waves through optical fibers, etc. We determine the useful and further general exact traveling wave solutions of the above mentioned NLDEs by applying the exp(−τ(ξ))-expansion method by aid of traveling wave transformations. Furthermore, we explain the physical significance of the obtained solutions of its definite values of the involved parameters with graphic representations in order to know the physical phenomena. Finally, we show that the exp(−τ(ξ))-expansion method is convenient, powerful, straightforward and provide more general solutions and can be helping to examine vast amount of travelling wave solutions to the other different kinds of NLDEs.

关键词： The Generalized KdV Equation The exp(-τ(ξ)) -Expansion Method Travelling Wave Solitary Wave

Remote condition monitoring of rail tracks using distributed acoustic sensing(DAS):A deep CNN-LSTM-SW based model

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Green Energy and Intelligent Transportation 2024年第5期3卷 70-85页

作者： md.Arifur rahman Suhaima Jamal Hossein Taheri The Laboratory for Advanced Non-Destructive Testing In-situ Monitoringand Evaluation(LANDTIE)Department of Manufacturing EngineeringGeorgia Southern UniversityStatesboro 30458GAUSA Information Technology Department Georgia Southern UniversityStatesboro 30458GAUSA

Railroad condition monitoring is paramount due to frequent passage through densely populated *** significance arises from the potential consequences of accidents such as train derailments,hazardous materials leaks,or collisions which may have far-reaching impacts on communities and the surrounding *** a solution to this issue,the use of distributed acoustic sensing(DAS)-fiber optic cables along railroads provides a feasible tool for monitoring the health of these extended ***,analyzing DAS data to assess railroad health or detect potential damage is a challenging *** to the large amount of data generated by DAS,as well as the unstructured patterns and substantial noise present,traditional analysis methods are ineffective in interpreting this *** paper introduces a novel approach that harnesses the power of deep learning through a combination of CNNs and LSTMs,augmented by sliding window techniques(CNN-LSTM-SW),to advance the state-of-the-art in the railroad condition monitoring *** well as it presents the potential for DAS and fiber optic sensing technologies to revolutionize the proposed CNN-LSTM-SW model to detect conditions along the rail track *** insights from the data of High tonnage load(HTL)-a 4.16 km fiber optic and DAS setup,we were able to distinguish train position,normal condition,and abnormal conditions along the ***,our investigation demonstrated that the proposed approaches could serve as efficient techniques for processing DAS signals and detecting the condition of railroad infrastructures at any remote distance with DAS-Fiber optic cable ***,in terms of pinpointing the train's position,the CNN-LSTM architecture showcased an impressive 97%detection *** a sliding window,the CNN-LSTM labeled data,the remaining 3%of misclassified labels have been improved dramatically by predicting the exact locations of each type of ***,these prop

关键词： Distributed acoustic sensing(DAS)-Fiber optic cable Railroad condition monitoring and anomaly detection High tonnage load(HTL) Convolutional neural network-long short-term memory-sliding window(CNN-LSTM-SW)

Rural Resilience: A Comprehensive Study on Water Supply, Sanitation, Disease Patterns, and Hygiene Practices in Munshiganj, Bangladesh

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Journal of Environmental Protection 2024年第1期15卷 63-75页

作者： Jubayer Hoque Rifat Islam md. Mustafizur rahman md. Golam Rabbani md. Selim Reja Saifur rahman Soykat Saim Raiyan md. Shafiqul Ahsan Emon Sakil Khan Department of Environmental Science and Disaster Management Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalgnj Bangladesh Department of Political Science Bangabandhu Sheikh Mujibur Rahman Science and Technology University GopalgnjBangladesh Department of Statistics Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalgnj Bangladesh

This research project investigates the current status of water supply, sanitation, and hygiene practices in Munshiganj District, Bangladesh. Data collection involved a structured questionnaire and a reconnaissance survey. Findings reveal that 30% of individuals rely on surface water (hand-tube wells, rivers, and ponds), prioritized as canal > river > pond, while 70% depend on groundwater (subterranean electric motor, deep tube-well). Drinking water is generally sufficient, with 95% reporting adequacy throughout the year. About 45% use hand tube-well water, 28% use deep tube-well water, and 11% use supply tap water for various purposes. Bathing trends include underground water through electric motor > pond > hand tube-well water > river, while for cooking, the order is underground water through electric motor > pond > hand tube-well water > river. Toilet water supply ranks as supply tap water > hand tube-well water > deep tube-well water. Although sanitation awareness is high, some lack knowledge of good hygiene practices. After defecating, handwashing methods include soap, ash, soil, or water. Children’s waste disposal varies, with some discarding it in open areas. Approximately 40% suffer from diseases like Diarrhoea due to unsafe water, primarily affecting children and elders. Training exists, but a significant portion lacks sanitation education. Dry skin or exposure to cold water may cause temporary irritation. Local government involvement in sanitation efforts is less active compared to non-governmental organizations. Results emphasize the need to enhance community awareness of safe water supplies and sanitation practices. .

关键词： Water Supply Sanitation Practices Hygiene Awareness Groundwater Dependency Community Health Intervention

Tracking of microplastics distribution patterns and their characterisation in deposited road dust from Dhaka city,Bangladesh

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Emerging Contaminants 2024年第3期10卷 386-399页

作者： Mohammad Toha R-Rafiul rahman Sadia Sikder md.Ahedul Akbor md.Mostafizur rahman Department of Environmental Science Bangladesh University of ProfessionalsMirpurCantonmentDhaka1216Bangladesh Department of Environmental Sciences Jahangirnagar UniversitySavarDhaka1342Bangladesh Laboratory of Environmental Health and Ecotoxicology Department of Environmental SciencesJahangirnagar UniversitySavarDhaka1342Bangladesh Institute of National Analytical Research and Service(INARS) Bangladesh Council of Scientific and Industrial Research(BCSIR)DhanmondiDhaka1205Bangladesh

The widespread presence of microplastics(MPs)in road dust has considerable concern regarding their potential risks to ecosystems and human *** the massive production of plastic,the erudition of MPs distribution patterns in various sizes of deposited road dust is still limited around the ***,the aim of this research is to provide an unambiguous picture of MPs distributional pattern,identification,classification,quantification,and features from road dust in various zones and types of roadways in Dhaka,*** study examined MPs in road dust samples with particle sizes ranging from 300 to 150 mm(Group-A),149-75 mm(Group-B),andunpaved road(325 items/5 g)>soil samples(294 items/5 g),roadside dust samples(284 items/5 g),and mid-road(283 items/5 g).By taking into account all sizes of road dust samples,the MPs were classified as fiber(70.26%),fragment(26.12%),beads(0.66%),films(1.32%),and foams(1.58%).It was found that adults inhaled MPs an average of 1612 items/day,while they ingested an average of 880 items/*** had an inhalation rate of 1232 items/day and an ingestion rate of 10267 items/day,which was 4e17 times greater than in other *** study identified 22 MPs polymer types,and SEM results show that MPs surfaces are being weathered into nanoplastics,creating a more hazardous environment.

关键词： Microplastics Road dust SEM FTIR Health impact Distribution pattern

Thornthwaite moisture index and depth of suction change under current and future climate‒An Australian study

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1761-1775页

作者： md.Rajibul Karim Bikash Devkota md.Mizanur rahman Hoang Bao Khoi Nguyen UniSA STEM University of South AustraliaMawson Lakes CampusMawson LakesSouth Australia5095Australia

Climate change is one of the major global challenges and it can have a significant influence on the behaviour and resilience of geotechnical *** changes in moisture content in soil lead to effective stress changes and can be accompanied by significant volume changes in reactive/expansive *** volume change leads to ground movement and can exert additional stresses on structures founded on or within a shallow depth of such *** change is likely to amplify the ground movement potential and the associated problems are likely to *** effect of atmospheric boundary interaction on soil behaviour has often been correlated to Thornthwaite moisture index(TMI).In this study,the long-term weather data and anticipated future projections for various emission scenarios were used to generate a series of TMI maps for *** changes in TMI were then correlated to the depth of suction change(H s),an important input in ground movement *** all climate scenarios considered,reductions in TMI and increases in H s values were observed.A hypothetical design scenario of a footing on expansive soil under current and future climate is *** is observed that a design that might be considered adequate under the current climate scenario,may fail under future scenarios and accommodations should be made in the design for such events.

关键词： Climate change Future prediction Thornthwaite moisture index(TMI) Characteristic surface movement Infrastructure resilience