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Cutaneous Abnormalities in Chronic Kidney Disease Patients with and without Dialysis

Journal of Biosciences and Medicines 2020年第1期8卷 64-76页

作者： md. Obaidur Rahman Muhammad Rafiqul Alam Asia Khanam md. Rezaul Alam md. kabir hossain A. K. M. Shahidur Rahman Fahmida Haque Department of Nephrology Cumilla Medical College & Hospital Cumilla Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Dermatology CARe Medical College & Hospital Dhaka Bangladesh

Background: Chronic kidney disease (CKD) is increasingly prevalent worldwide. CKD may present with different cutaneous manifestations. Objectives: To evaluate the dermatological manifestations and compare these manifestations between patients with maintenance hemodialysis (MHD) and non-dialysis groups. Methods: It was a cross sectional study conducted in the Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from April 2013 to March 2014. A total of 150 hospital admitted CKD patients were evaluated for dermatological manifestations. Age, gender, haemoglobin level, 24-hours urinary total protein (UTP), serum creatinine, serum fasting lipid profile, estimated glomerular filtration rate (e-GFR) and dermatological manifestations of the study subjects were recorded accordingly. Inter-group comparisons were made between patients with and those without cutaneous abnormality. Results: Out of 150 study subjects, 99 (66%) were male and 51 (34%) were female, 69 (46%) patients were on MHD and 81 (54%) patients were without dialysis, their mean (±SD) age was 44.6 ± 12.3 year. A Total of 126 (84%) patients had cutaneous abnormalities;among them 69 (54.76%) were pre-dialytic and 57 (45.24%) were on MHD group. The mean (±SD) serum creatinine was relatively higher but haemoglobin level was significantly lower (p = 0.021), while UTP was significantly higher (p = 0.038) among patients with cutaneous abnormality. There was no relationship between lipid profile with cutaneous abnormality. Among 126 (84%) patients with cutaneous abnormality;pallor was the most common cutaneous abnormality (72%) followed by xerosis (68.66%), pruritus (65.33%), half and half nails (38.66%), pigmentation (33.33%), purpura/ecchymosis (16.66%), fungal infection (16%), ulcerative stomatitis (10.66%) and bacterial infection (10%). Pigmentation (52.6%), purpura (35.1%), ulcerative stomatitis (21.1%) and bacterial infection (19.3%) were significantly higher in MHD gro

关键词： Chronic Kidney Disease (CKD) Cutaneous Manifestations Maintenance Hemodialysis (MHD)

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Serum Vitamin D Associated with Insulin Secretory Function in Impaired Fasting Glucose Subjects

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Journal of Biosciences and Medicines 2019年第1期7卷 83-98页

作者： A. K. M. Shahidur Rahman md. Arifuzzaman Sohel Farjana Rahman Bhuiyan Fahad Al Shatil Ashrafee md. kabir hossain Syed Fazlul Islam Mohammad Ibrahim Ali Rahelee Zinnat Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Biochemistry & Cell Biology Bangladesh University of Health Sciences (BUHS) Dhaka Bangladesh Department of Urology Dhaka Medical College Hospital Dhaka Bangladesh

Background: Impaired fasting glucose (IFG) is a prediabetic condition and is a high-risk state for developing diabetes and associated complications. The aim of this study was to explore the association of vitamin D with insulin secretory function among the IFG subjects. Materials and Methods: This was a prospective cross-sectional study conducted in the Department of Biochemistry and Cell Biology, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh;from June 2016 to May 2017, on forty-six (46) IFG subjects. Serum blood glucose was measured by glucose-oxidase method, Fasting serum lipid profile (Total cholesterol, TG and HDL-c);liver enzyme like alanine aminotransferase (ALT) was measured by enzymatic-colorimetric method;Serum creatinine was measured by colorimetric kinetic method;Serum Insulin and vitamin D [25(OH)D] were measured by ELISA method;insulin secretory capacity (HOMA%B) and insulin sensitivity (HOMA%S) were calculated by Homeostasis Model Assessment (HOMA) using HOMA-CIGMA software. Results: Among 46 IFG subjects, 22 (47.8%) were male and rest 24 (52.2%) were female and their mean age was 40 (±8) years. Mean fasting serum glucose level of the study subjects was 6.33 (±0.23) mmol/l and mean postprandial serum glucose level was 7.23 (±0.41) mmol/l. Mean serum vitamin D level of the study subjects was 26.54 (±8.83) ng/ml. Mean HOMA%S, HOMA%B and HOMA%IR of the total study subjects were 48.34 (±16.70), 102.16 (±23.13) and 2.28 (±0.70) respectively. Insulin secretory capacity (HOMA%B) was significantly higher (p = 0.047) in the subjects having higher vitamin D [25(OH)D level ≥ 20 ng/ml] compared to the subjects having lower vitamin D [25(OH)D levels Conclusion: High prevalence of hypovitaminosis D exists among IFG subjects. Vitamin D is associated with insulin secretory function in IFG subjects. Population based prospective studies using larger sample size should be done to confirm the results.

关键词： Impaired Fasting Glucose (IFG) Insulin Secretory Capacity Insulin Sensitivity Prediabetes Vitamin D

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Multi-species probiotics enhance survival,growth,intestinal microbiota and disease resistance of rohu(Labeo rohita)larvae

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Water Biology and Security 2024年第1期3卷 71-79页

作者： Zannatul Ferdous md.kabir hossain md.Hadiuzzaman SMRafiquzzaman KM Abdul Halim Tanvir Rahman md.Ali Reza Faruk Zulhisyam Abdul Kari md.Shahjahan Laboratory of Fish Ecophysiology Department of Fisheries ManagementBangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Aquaculture Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Fisheries Matshoy BhabanDhakaBangladesh Department of Fisheries Biology&Aquatic Environment Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Agricultural Sciences Faculty of Agro-Based IndustryUniversiti Malaysia KelantanJeli Campus17600JeliKelantanMalaysia

Multi-strain probiotics provide the most dependable approaches to improve health,immune response,and disease resistance in farmed *** the present study,we examined the effects of multi-species probiotics on the survival,growth,immune response,and disease resistance of rohu(Labeo rohita)*** hatched larvae from the day of first feeding(average weight of 0.003 g)were reared with multi-species probiotics having a combination of Bacillus subtilis(109 colony forming units(cfu)/mL)and Lactobacillus spp.(Lactobacillus plantarum,Lactobacillus buchneri-1011 cfu/mL)in water containing doses of 0(control-C),0.5 mL/L(treatment 1-T1),and 1.0 mL/L(treatment 2-T2)in triplicates for 90 *** the experiment,a challenge test was performed to assess the fish's resistance to pathogenic Aeromonas *** higher survival was recorded in larvae of treated groups(87%in T2 and 79%in T1)compared to the control(62%).Significantly higher growth performance(weight gain and specific growth rate—SGR)was shown by the probiotic-treated larval groups compared to the *** supplementation resulted in significantly higher counts of total viable colony(TVC)and lactic acid bacteria(LAB)in the *** immunological parameters(mucosal fold fattening,goblet cell abundance,expansion of lamina propria and enterocytes)of the gut were significantly better in probiotic-treated *** liver of treated fish showed irregular shape nuclei turning into regular shape and reducing spaces between the hepatic ***-treated fish had the highest post-challenge survival rate(90%)against *** *** erythrocytes of challenged fish treated with probiotics had significantly lower frequencies of various nuclear and cellular *** findings suggest that multi-species probiotic supplements could improve the survival,growth,health status,and immune response of rohu in the early stages of its development.

关键词： Aquaculture Disease resistance Immunity Labeo rohita Probiotics

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Incidence, Risk Factors and Short Term Outcome of Acute Kidney Injury among Patients with Acute Coronary Syndrome

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Journal of Biosciences and Medicines 2020年第5期8卷 177-188页

作者： md. kabir hossain Muhammad Rafiqul Alam Asia Khanam A. K. M. Shahidur Rahman Rafi Nazrul Islam Syed Fazlul Islam Mohammad Kamrul Ahsan S. K. Mamun-Ar-Rashid Tanvir Rahman md. Nazmul Hasan Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Nephrology & Dialysis BIRDEM General Hospital Dhaka Bangladesh Holy Family Red Crescent Medical College Hospital (HFRCMCH) Dhaka Bangladesh Department of Medicine Khulna Medical College Hospital Khulna Bangladesh Department of Nephrology United Hospital Limited Dhaka Bangladesh Department of Cardiology Ad-din Medical College Hospital Dhaka Bangladesh

Background: Cardio-renal syndrome is the leading cause of death globally. Acute kidney injury (AKI) is a major complication among patients admitted in Coronary Care Unit (CCU) with acute coronary syndrome (ACS). AKI in ACS patients is associated with higher morbidity, mortality and prolong hospital stay. Objective: To determine the incidence, risk factors and short term outcome of acute kidney injury (AKI) among the patients admitted in CCU with ACS. Methods: This cross sectional study was conducted at Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2013 to December 2013. Following selection criteria a total of two hundred (200) patients with ACS were studied. AKI was defined according to the KDIGO guideline and further categorized by RIFLE criteria. Data of patients with AKI and those without AKI were analyzed and compared by statistical tests. Results: Majority of the study patients were male (79.5%). AKI was developed in 40 of the 200 study patients (20.0%). The mean (±SD) age of the study patients was 60.1 ± 11.1 years in patients with AKI and 55.9 ± 10.1 years in patients without AKI. Our data analysis showed that older age (>65 years), diabetes mellitus, dyslipidemia and smoking were significantly correlated to the development of AKI. Mortality was significantly high in AKI group (7.15%) compared to no AKI group (1.25%). Out of 27 patients who achieved renal recovery most (80.8%) belonged to risk class. Severity of AKI showed significant effect on renal recovery and final outcome. Conclusion: This study demonstrated that, incidence of AKI among patients with ACS was 20%. Elderly patients, diabetes mellitus, dyslipidemia, and exposure to smoking were significantly associated with development of AKI in ACS.

关键词： Acute Kidney Injury (AKI) Acute Coronary Syndrome (ACS) Cardio-Renal Syndrome

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Nipah Virus Unveiled: A Review Article

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Advances in Bioscience and Biotechnology 2024年第3期15卷 161-173页

作者： Munama Magdum md. Abir Tazim Chowdhury Mahmuda Khandaker Razdip Datta md. Naheed Rayhan md. Siffat Uddin md. Junayed Imam Bhuiyan md. Ahaduzzaman md. Abdullah Al-Mahammud kabir Mohammad Zishan Uddin md. Estiak Ullah Sahid Subrata Saha Department of Community Medicine Shaheed Monsur Ali Medical College Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Microbiology Shaheed Monsur Ali Medical College Dhaka Bangladesh Department of Anesthesia Dhaka Dental College & Hospital Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Medicine Times Multicare Hospital Ltd. Dhaka Bangladesh Barking Havering and Redbridge University Hospitals NHS Trust Romford UK

Nipah virus (NiV) is a highly infectious zoonotic pathogen that poses a significant threat to human and animal health. First identified in Malaysia in 1998, NiV has since caused several outbreaks in Southeast Asia, with sporadic cases reported in Bangladesh and India. The virus is primarily transmitted to humans through direct contact with infected animals, primarily fruit bats, or through the consumption of contaminated fruits and their juices. NiV infection presents a wide spectrum of clinical features, ranging from mild respiratory illness to severe encephalitis, with a high case fatality rate. The incubation period typically ranges from 4 to 14 days, during which patients develop fever, headache, myalgia, and respiratory symptoms such as cough and sore throat. As the disease progresses, neurological signs become prominent, including altered consciousness, seizures, and focal deficits. Severe cases may exhibit acute respiratory distress syndrome and multi organ failure. Laboratory findings often include lymphocytopenia, thrombocytopenia, and elevated liver enzymes. Diagnosis of NiV infection requires specialized laboratory testing, including reverse transcription-polymerase chain reaction (RT-PCR) and serological assays. Currently, no specific antiviral treatment exists for NiV infection, and management primarily focuses on supportive care. Prevention and control strategies encompass public health interventions, surveillance, and raising awareness among healthcare providers and the general population. The emergence and re-emergence of NiV highlight the urgent need for continued research, improved diagnostic capabilities, and the development of effective vaccines and therapeutics to mitigate the impact of this deadly virus.

关键词： Nipah Virus Zoonotic Pathogen Outbreaks Surveillance

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Structural Style and Hydrocarbon Prospectivity of the Growth Faults Related Structures in the Bengal Basin

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Journal of Geoscience and Environment Protection 2024年第8期12卷 197-218页

作者： md. Fazle Rabbi Joy md. Mostafizur Rahman S. M. Mainul kabir Tamanna Binte Arfan Farhad Hsossain Department of Geology University of Dhaka Dhaka Bangladesh

The structural and tectonic evolution of the Bengal Basin is characterized by a complex interplay of factors, including sedimentation, the rise of the Himalayan Mountains, and the movements of Jurassic syn-rift faults. This study aims to comprehend the progression of growth faults inside the basin by examining fault geometry, basin development, and structural relief patterns. We used high-quality 2D seismic lines from the PK-MY-8403, classical seismic interpretation techniques and modeling were carried out to reveal the plate tectonic conditions, stratigraphy, and sedimentation history of the basin. The break-up unconformity, Paleocene and Eocene submerged conditions, and crucial geological formations including the Sylhet Limestone, Barail Group, and Surma Group were among the notable features recognized in seismic section. With an emphasis on growth strata and pre-growth strata, significant variations in layer thickness and relief were remarked in different stratigraphic levels. Basin development events like the evolution of the Miocene remnant ocean basin, sedimentation in Oligocene, Eocene Himalayan collision, and the Pliocene reverse fault development are analyzed. In the early the Pliocene compressional forces outpaced sedimentation rates and syn-depositional normal faults of Oligocene time began to move in opposite direction. Syn-depositional growth faults may have formed in the Bengal Basin as a result of this reversal. This research provides a detailed comprehensive knowledge of growth fault development in the Bengal Basin following the seismic interpretation, modelling, and thickness/relief analysis. The outcomes point to a substantial hydrocarbon potential, especially in regions like the Eocene Hinge Zone, where the prospectivity of the area is enhanced by carbonate reefs and Jalangi shale. However, the existence of petroleum four-way closure in the investigated region requires further investigation.

关键词： Plate Tectonic Subsidence History Structural Relief Syn-Depositional Model Growth Fault Petroleum System

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Pattern of Eye Diseases among Tea Workers

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Open Journal of Ophthalmology 2024年第2期14卷 117-127页

作者： Rifat Binth Rezayee md. Showkat kabir Mohammed Moinul Hoque Nirupam Chowdhury Mohammad Shish Rahman Nawreen Binte Anwar Shah-Noor Hassan Department of Community Ophthalmology Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Ophthalmology Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh

Background: Bangladesh’s tea industry is essential to the country’s economic expansion. Since tea workers in Bangladesh are marginalized within our community, they have limited access to comprehensive eye care services. Productivity and well-being are cornerstones of comprehensive health care strategy. Ocular disorders are influenced by life expectancy, sociodemographic status, and the epidemiological transition. In this context, the state of ocular health and the many eye illnesses remain to be significantly addressed. Purpose: To evaluate the pattern of eye diseases among tea workers in a tea estate of Bangladesh. Methods: This cross-sectional observational study was carried out in Halda Valley Tea Estate, Nazirhat, Fatickchari, Chattogram, Bangladesh, under the supervision of the Department of Community Ophthalmology, BSMMU, following ethical clearance and approval by the IRB board of BSMMU. With informed written consent and approval from the authority of the tea estate, a total of 110 tea workers were recruited. Socio-demographic characteristics, ocular findings, and patterns of eye diseases were determined and recorded. Results: The mean age of the study participants was 39.60 ± 11.63 years. The maximum (58.1%) study participants were 31 - 50 years old, female (64.5%), illiterate (82.7%), and tribal (71.8%) indigenes. Eye diseases were found in 94.5% of workers. Presbyopia (28.2%), cataracts (27.3%), and refractive error (26.4%) were the most common. Tea workers with eye diseases were significantly older than those who did not have any eye diseases (40.20 ± 11.57 vs. 29.17 ± 7.31 years, p Conclusion: A significant number of tea workers had eye diseases, of which presbyopia, cataracts, and refractive error were the most common.

关键词： Tea Workers Eye Diseases Presbyopia Cataract Refractive Errors

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Nipah Virus Unveiled: A Review Article

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Advances in Bioscience and Biotechnology（生命科学与技术进展） 2024年第3期 161页

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Temperature Effect on Stabilizing TiO2/Ag Composite Nanoparticles on Polyester Fabric for the Enhancement of Antibacterial Durability

Temperature Effect on Stabilizing TiO2/Ag Composite Nanopart...

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作者： Shawon md. Rashidul kabir 浙江理工大学

学位级别：硕士

Metal nanoparticles（MNPs）are recognized as a class of antimicrobial reagent for textile ***,their weak adhesion on polymeric fibers will cause unwanted loss of MNPs,resulting in an unsatisfied antibacterial durability,and even serious impact on the environment and human *** enhance the stability of the MNPs immobilized on fabrics,several approaches have been investigated by the other researchers so far,but achievement of stable immobilization and antibacterial durability still remain *** such as Cu,Fe,Ag,TiO2,Zn,and Ag are highly used in the textile sector for antibacterial *** these NPs have poor washing durability without ***,we propose a heating process for stabilizing TiO2 and Ag NPs on a plasma-treated polyester fabric without using any *** fabric was fabricated by dipping in solution followed by one step heat pressing and reduction using sodium *** polyester fabric is functionalized using cold plasma treatment for enhancing the adhesion and stabilizing of Titanium and Silver Nano *** process was repeated until the significant amounts of the TiO2-Ag NPs were *** temperature effect on the immobilization of the inorganic particles was *** surface morphology of the coated fabric samples was analyzed using Field Emission Scanning Electron Microscope,as well as the elemental analysis was achieved using X-ray powder diffraction,Fourier-transform infrared spectroscopy *** results showed that the surface of the fabric after plasma modification,the fiber surface was highly loaded with Ag-TiO2 *** adhesion and fixation of the NPs were significantly improved the increasing the *** higher temperature range showed higher fixation of the NPs inside the *** found that the heating process could endow the finishing fabric with superior antibacterial ability and durability when the temperature was higher than 150℃,as the bacterial reduction

关键词： OxygenPlasma heat-press antibacterial performance washingdurability nanoparticles

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Design of a High-Gain 2 × 1 Array Antenna for S-Band Applications

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World Journal of Engineering and Technology 2023年第2期11卷 293-302页

作者： md. Imran hossain md. Ariful Islam md. Tofail Ahmed md. Humaun kabir Department of Electrical Electronic and Communication Engineering Pabna University of Science and Technology Pabna Bangladesh Department of Electrical and Electronic Engineering Pabna University of Science and Technology Pabna Bangladesh Department of Information and Communication Engineering Pabna University of Science and Technology Pabna Bangla-desh Department of Computer Science and Engineering Bangamata Sheikh Fojilatunnesa Mujib Science & Technology University Jamalpur Bangladesh

Antennas are an indispensable element in wireless networks. For long-distance wireless communication, antenna gains need to be very strong (highly directive) because the signal from the antenna loses a lot of strength as it travels over long distances. This is true in the military with missile, radar, and satellite systems, etc. Antenna arrays are commonly employed to focus electromagnetic waves in a certain direction that cannot be achieved perfectly with a single-element antenna. The goal of this study is to design a rectangular microstrip high-gain 2 × 1 array antenna using ADS Momentum. This microstrip patch array design makes use of the RT-DUROID 5880 as a substrate with a dielectric constant of 2.2, substrate height of 1.588 mm, and tangent loss of 0.001. To achieve efficient gain and return loss characteristics for the proposed array antenna, RT-Duroid is a good choice of dielectric material. The designed array antenna is made up of two rectangular patches, which have a resonance frequency of 3.3 GHz. These rectangular patches are excited by microstrip feed lines with 13 mm lengths and 4.8 mm widths. The impedance of the patches is perfectly matched by these transmission lines, which helps to get better antenna characteristics. At a resonance frequency of 3.3 GHz, the suggested antenna array has a directivity of 10.50 dB and a maximum gain of 9.90 dB in the S-band. The S parameters, 3D radiation pattern, directivity, gain, and efficiency of the constructed array antenna are all available in ADS Momentum.

关键词： Microstrip Patch Antenna Array Antenna Microstrip Feed Rectangular Patch Gain Efficiency Directivity ADS

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