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Growth inhibitory response and ultrastructural modification of oral-associated candidal reference strains (ATCC) by Piper betle L. extract

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International Journal of Oral Science 2014年第1期6卷 15-21页

作者： Mohd-Al-Faisal Nordin Wan Himratul-Aznita Wan Harun Fathilah Abdul Razak md yusoff musa Department of Oral Biology and Biomedical Sciences Faculty of Dentistry University of Malaya Institute of Biological Sciences Faculty of ScienceUniversity of Malaya

Candida species have been associated with the emergence of strains resistant to selected antifungal agents. Plant products have been used traditionally as alternative medicine to ease mucosal fungal infections. This study aimed to investigate the effects of Piper betle extract on the growth profile and the ultrastructure of commonly isolated oral candidal cells. The major component of Po betle was identified using liquid chromatography-mass spectrophotometry （LC-MS/MS）. Seven ATCC control strains of Candida species were cultured in yeast peptone dextrose broth under four different growth environments：（i） in the absence of P. betle extract; and in the presence of P. beUeextract at respective concentrations of （ii） 1 ***-1; （iii） 3 ***-1; and （iv） 6 ***- 1 The growth inhibitory responses of the candidal cells were determined based on changes in the specific growth rates （μ）. Scanning electron microscopy （SEM） was used to observe any ultrastructural alterations in the candida colonies. LC-MS/MS was performed to validate the presence of bioactive compounds in the extract. Following treatment, it was observed that the p-values of the treated cells were significantly different than those of the untreated cells （P〈0.05）, indicating the fungistatic properties of the P. beUe extract. The candidal population was also reduced from an average of 13.44× 10^6 to 1.78×10^6 viable cell counts （CFU）.mL-1, SEM examination exhibited physical damage and considerable morphological alterations of the treated cells. The compound profile from LC-MS/MS indicated the presence of hydroxybenzoic acid, chavibetol and hydroxychavicol in P. betle extract. The effects of P. betle on candida cells could potentiate its antifungal activity.

关键词： antifungal activity Candida cell morphology growth inhibitory effect Piperbetle L.

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Bioluminescent fungi from Peninsular Malaysia-a taxonomic and phylogenetic overview

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Fungal Diversity 2015年第1期70卷 149-187页

作者： Audrey L.C.Chew Dennis E.Desjardin Yee-Shin Tan md yusoff musa Vikineswary Sabaratnam Mushroom Research Centre University of Malaya50603 Kuala LumpurMalaysia Institute of Biological Sciences Faculty of ScienceUniversity of Malaya50603 Kuala LumpurMalaysia Department of Biology San Francisco State University1600 Holloway Ave.San FranciscoCA 94132USA

Fifteen bioluminescent fungi recently collected from Peninsular Malaysia are analysed *** phylogeny of the Malaysian bioluminescent fungi and closely related taxa were evaluated with molecular data from the nuclear ribosomal large subunit(LSU),RNA polymerase 2 second largest subunit(RPB2)and internal transcribed spacers(ITS)gene *** sequences data support the circumscription of species based on the morphological species concept,but was unable to fully support the current sectional delimitation of genus *** the 15 taxa analysed here,four are novel species described herein,*** gombakensis,***,*** and Panellus luxfilamentus;while four taxa of Mycena *** were recently described as *** species(***)represents a new distribution record to Peninsular Malaysia,and six species(Neonothopanus nambi,Filoboletus manipularis,***,Roridomyces pruinosoviscidus,*** and ***)have been previously *** pruinosoviscidus is accepted as a new combination based on morphological and phylogenetic *** morphology data indicate its potential for taxon delimitation as axenic cultures of each species produced unique and distinguishable *** descriptions,illustrations and photographs are provided on basidiome and culture morphology.A key to aid in species identification,comparisons with allied species and data on basidiome and mycelium luminescence are also *** study gives the first report on mycelial luminescence for ***,***,*** as well as all new species described *** reports in this study bring the total known luminescent fungi worldwide to 81 species.

关键词： Basidiomycete Biodiversity Culture morphology Filoboletus Mycena Neonothopanus Panellus Phylogeny Roridomyces Systematics Taxonomy

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Japanese Sign Language Recognition by Combining Joint Skeleton-Based Handcrafted and Pixel-Based Deep Learning Features with Machine Learning Classification

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2605-2625页

作者： Jungpil Shin md.Al Mehedi Hasan Abu Saleh musa Miah Kota Suzuki Koki Hirooka School of Computer Science and Engineering The University of AizuAizuwakamatsu965-8580Japan Department of Computer Science&Engineering Rajshahi University of Engineering&TechnologyRajshahi6204Bangladesh

Sign language recognition is vital for enhancing communication accessibility among the Deaf and hard-of-hearing *** Japan,approximately 360,000 individualswith hearing and speech disabilities rely on Japanese Sign Language(JSL)for ***,existing JSL recognition systems have faced significant performance limitations due to inherent *** response to these challenges,we present a novel JSL recognition system that employs a strategic fusion approach,combining joint skeleton-based handcrafted features and pixel-based deep learning *** system incorporates two distinct streams:the first stream extracts crucial handcrafted features,emphasizing the capture of hand and body movements within JSL ***,a deep learning-based transfer learning stream captures hierarchical representations of JSL gestures in the second ***,we concatenated the critical information of the first stream and the hierarchy of the second stream features to produce the multiple levels of the fusion features,aiming to create a comprehensive representation of the JSL *** reducing the dimensionality of the feature,a feature selection approach and a kernel-based support vector machine(SVM)were used for the *** assess the effectiveness of our approach,we conducted extensive experiments on our Lab JSL dataset and a publicly available Arabic sign language(ArSL)*** results unequivocally demonstrate that our fusion approach significantly enhances JSL recognition accuracy and robustness compared to individual feature sets or traditional recognition methods.

关键词： Japanese Sign Language(JSL) hand gesture recognition geometric feature distance feature angle feature GoogleNet

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An Enhanced Hybrid Model Based on CNN and BiLSTM for Identifying Individuals via Handwriting Analysis

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1689-1710页

作者： md.Abdur Rahim Fahmid Al Farid Abu Saleh musa Miah Arpa Kar Puza md.Nur Alam md.Najmul Hossain Sarina Mansor Hezerul Abdul Karim Department of Computer Science and Engineering Pabna University of Science and TechnologyPabna6600Bangladesh Faculty of Engineering Multimedia UniversityCyberjaya63100Malaysia Department of Computer Science and Engineering Bangladesh Army University of Science and TechnologySaidpur5311Bangladesh Department of Mathematics Pabna University of Science and TechnologyPabna6600Bangladesh Department of Electrical Electronic and Communication EngineeringPabnaUniversity of Science and TechnologyPabna6600Bangladesh Department of Electrical and Communication Engineering Pabna University of Science and TechnologyPabna6600Bangladesh

Handwriting is a unique and significant human feature that distinguishes them from one *** are many researchers have endeavored to develop writing recognition systems utilizing specific signatures or symbols for person identification through ***,such systems are susceptible to forgery,posing security *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** innovative method is intricately designed,encompassing five distinct phases:data collection,preprocessing,feature extraction,significant feature selection,and *** key advancement lies in the creation of a novel dataset specifically tailored for Bengali handwriting(BHW),setting the foundation for our comprehensive ***-preprocessing,we embarked on an exhaustive feature extraction process,encompassing integration with kinematic,statistical,spatial,and composite *** meticulous amalgamation resulted in a robust set of 91 *** enhance the efficiency of our system,we employed an analysis of variance(ANOVA)F test and mutual information scores approach,meticulously selecting the most pertinent *** the identification phase,we harnessed the power of cutting-edge deep learning models,notably the Convolutional Neural Network(CNN)and Bidirectional Long Short-Term Memory(BiLSTM).These models underwent rigorous training and testing to accurately discern individuals based on their handwriting ***,our methodology introduces a groundbreaking hybrid model that synergizes CNN and BiLSTM,capitalizing on fine motor features for enhanced individual ***,our experimental results unde

关键词： Bengali handwriting(BHW) person identification convolutional neural network(CNN) BiLSTM

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Peat properties of a tropical forest reserve adjacent to a fire-break canal

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Journal of Forestry Research 2024年第1期35卷 155-167页

作者： Dayang Nur Sakinah musa Mohd Zahirasri Mohd Tohir Xinyan Huang Luqman Chuah Abdullah Mohamad Syazaruddin md Said Muhammad Firdaus Sulaiman Safety Engineering Interest Group(SEIG) Department of Chemical and Environmental EngineeringFaculty of EngineeringUniversiti Putra Malaysia43400 UPM SerdangSelangorMalaysia International Tropical Forestry Programme Faculty of Tropical ForestryUniversiti Malaysia SabahSabahMalaysia Department of Land Management Faculty of AgricultureUniversiti Putra MalaysiaSelangorMalaysia Research Centre for Fire Safety Engineering Department of Building Environment and Energy EngineeringThe Hong Kong Polytechnic UniversityHong KongPeople’s Republic of China

Tropical peat comprises decomposed dead plant material and acts like a sponge to absorb water,making it fully ***,drought periods dry it readily and increases its vulnerability to *** fires emit greenhouse gases and particles contributing to haze,and prevention by constructing fire-break canals to reduce fire spread into forest reserves is *** paper aims to determine peat physical and chemical properties near a fire-break canal at different fire frequency *** sampling was conducted at two forest reserves in Malaysia which represent low fire frequency and high fire frequency *** results show that peat properties were not affected by the construction of a fire-break canal,however lignin and cellulose content increased significantly from the distance of the canal in both *** study concluded that fire frequency did not significantly influence peat properties except for *** higher fibre content in the high frequency area did not influence moisture content nor the ability to regain ***,fire frequency might contribute differently to changes in physical and chemical properties,hence management efforts to construct fire-break canals and restoration efforts should protect peatlands from further *** findings will benefit future management and planning for forest reserves.

关键词： Peat fire Peat properties Fire-break canals Forest reserves

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Virtual Keyboard:A Real-Time Hand Gesture Recognition-Based Character Input System Using LSTM and Mediapipe Holistic

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Computer Systems Science & Engineering 2024年第2期48卷 555-570页

作者： Bijon Mallik md Abdur Rahim Abu Saleh musa Miah Keun Soo Yun Jungpil Shin Department of Computer Science and Engineering Pabna University of Science and TechnologyPabna6600Bangladesh School of Computer Science and Engineering The University of AizuAizuwakamatsuFukushima965-8580Japan School of Computer and Information Technology Ulsan CollegeDong-guUlsan44610South Korea

In the digital age,non-touch communication technologies are reshaping human-device interactions and raising security concerns.A major challenge in current technology is the misinterpretation of gestures by sensors and cameras,often caused by environmental *** issue has spurred the need for advanced data processing methods to achieve more accurate gesture recognition and *** study presents a novel virtual keyboard allowing character input via distinct hand gestures,focusing on two key aspects:hand gesture recognition and character input *** developed a novel model with LSTM and fully connected layers for enhanced sequential data processing and hand gesture *** also integrated CNN,max-pooling,and dropout layers for improved spatial feature *** model architecture processes both temporal and spatial aspects of hand gestures,using LSTM to extract complex patterns from frame sequences for a comprehensive understanding of input *** unique dataset,essential for training the model,includes 1,662 landmarks from dynamic hand gestures,33 postures,and 468 face landmarks,all captured in real-time using advanced pose *** model demonstrated high accuracy,achieving 98.52%in hand gesture recognition and over 97%in character input across different *** excellent performance in real-time testing underlines its practicality and effectiveness,marking a significant advancement in enhancing human-device interactions in the digital age.

关键词： Hand gesture recognition M.P.holistic open CV virtual keyboard LSTM human-computer interaction

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Groundwater arsenic poisoning in a primary educational institution:health risks to school-going children

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Acta Geochimica 2022年第6期41卷 1069-1082页

作者： md.Sohel Rana md.Jahangir Alam mdAbu musa Sazal Kumar md.Aminur Rahman Zonal Laboratory Department of Public Health Engineering(DPHE)RangpurBangladesh Department of Chemistry Carmichael CollegeRangpurBangladesh Department of Applied Chemistry and Chemical Engineering Islamic UniversityKushtia7003Bangladesh School of Environmental and Life Sciences The University of NewcastleCallaghanNSW2308Australia Global Centre for Environmental Remediation(GCER) College of EngineeringScience and EnvironmentThe University of NewcastleCallaghanNSW2308Australia Zonal Laboratory Department of Public Health Engineering(DPHE)Jashore-7400Bangladesh

This study aimed to estimate arsenic(As)and iron(Fe)content in tubewell water(n=58)in primary educational institutions and subsequently assess the health risks to school-going *** described that the As concentration ranged between 0.002 and 0.994 mg L^(-1)with an average value of 0.044 mg L^(-1);which exceeded the World Health Organization(WHO)provisional guideline value of 0.01 mg L^(-1).Similarly,the Fe content varied from 0.05 to 10 mg L^(-1)averaging to 2.84 mg L^(-1).Samples of 55.17%contained a greater As concentration than0.01 mg L^(-1)and 18.97%greater than Bangladesh drinking water quality(BDWQ)standard of 0.05 mg L^(-1),***,75.86%of samples contained a higher Fe concentration than the maximum Bangladesh permissible limit of 1 mg L^(-1).Health risk assessment indicated that girls are more vulnerable than boys *** average hazard quotients(HQs)for As intake through drinking water were 6.01±17.85 and 7.41±22.03 for boys and girls,respectively,implying non-carcinogenic health risks to both *** HQs for Fe intake were less than threshold value of 1 indicating no health issues may arise from Fe intake ***,consumption of As and Fe may trigger health risks to students as indicated by the hazard index(HI),which was higher than *** average cancer risk(CR)values for both boys(0.0027±0.008)and girls(0.0033±0.0099)exceeded the threshold limit of 10-6-10-4,suggesting a possibility of lifetime cancer risks to the school-going ***,school authorities should find alternative ways to ensure safe drinking water for school-going children to avoid possible cancer and non-cancer health risks through consumption of As-poisoning water.

关键词： Arsenic Iron Human health risks Groundwater

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Rotation,Translation and Scale Invariant Sign Word Recognition Using Deep Learning

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Computer Systems Science & Engineering 2023年第3期44卷 2521-2536页

作者： Abu Saleh musa Miah Jungpil Shin md.Al Mehedi Hasan md Abdur Rahim Yuichi Okuyama School of Computer Science and Engineering The University of AizuAizuwakamatsuFukushima965-8580Japan Department of Computer Science and Engineering Pabna University of Science and TechnologyPabnaBangladesh

Communication between people with disabilities and people who do not understand sign language is a growing social need and can be a tedious *** of the main functions of sign language is to communicate with each other through hand *** of hand gestures has become an important challenge for the recognition of sign *** are many existing models that can produce a good accuracy,but if the model test with rotated or translated images,they may face some difficulties to make good performance *** resolve these challenges of hand gesture recognition,we proposed a Rotation,Translation and Scale-invariant sign word recognition system using a convolu-tional neural network(CNN).We have followed three steps in our work:rotated,translated and scaled(RTS)version dataset generation,gesture segmentation,and sign word ***,we have enlarged a benchmark dataset of 20 sign words by making different amounts of Rotation,Translation and Scale of the ori-ginal images to create the RTS version *** we have applied the gesture segmentation *** segmentation consists of three levels,i)Otsu Thresholding with YCbCr,ii)Morphological analysis:dilation through opening morphology and iii)Watershed ***,our designed CNN model has been trained to classify the hand gesture as well as the sign *** model has been evaluated using the twenty sign word dataset,five sign word dataset and the RTS version of these *** achieved 99.30%accuracy from the twenty sign word dataset evaluation,99.10%accuracy from the RTS version of the twenty sign word evolution,100%accuracy from thefive sign word dataset evaluation,and 98.00%accuracy from the RTS versionfive sign word dataset ***,the influence of our model exists in competitive results with state-of-the-art methods in sign word recognition.

关键词： Sign word recognition convolution neural network(cnn) rotation translation and scaling(rts) otsu segmentation

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Kappaphycus alvarezii waste biomass:A potential biosorbent for chromium ions removal

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Journal of Environmental Sciences 2011年第6期23卷 918-922页

作者： Oon Lee Kang Nazaruddin Ramli Mamot Said musa Ahmad Suhaimi md Yasir Arbakariya Ariff School of Chemical Sciences and Food Technology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 BangiSelangorMalaysia School of Sciences and Technology Universiti Malaysia Sabah88400 Kota KinabaluSabahMalaysia Faculty of Biotechnology and Biomolecular Science Universiti Putra Malaysia43400 SerdangSelangorMalaysia

The Cr（III） sorption experiments onto Kappaphycus alvarezii waste biomass were conducted at different pH values（2-6） under the conditions of initial metal concentration of 10-50 mg/L and the chemical compositions of Cr-Cu and *** Cr（III） sorption capacities were slightly dependent on pH,and the maximum sorption capacity was 0.86 mg/g at pH *** sorption capacities increased with increase in the initial metal concentration,whereas it was suppressed by the presence of Cu（II） and Cd（III） in the *** Cr（III） sorption equilibrium was evaluated using Langmuir,Freundlich and BET *** sorption mechanisms were characterised using scanning electron microscopy and Fourier transform infrared *** main mechanisms were ion exchange coupled with a complexation *** alvarezii waste biomass represents a potential for Cr（III） ion removal from aqueous solution.

关键词： biosorption chromium Kappaphycus alvarezii

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Free fatty acid-induced miR-22 inhibits gluconeogenesis via SIRT-1-mediated PGC-1α expression in nonalcoholic fatty liver disease

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iLIVER 2023年第1期2卷 1-9页

作者： Ajay K.Yadav Teja Naveen Sata Daksh Verma Amrendra K.Sah Amit K.Mishra Mrinalini md.musa Hossain Kishor Pant Senthil K.Venugopal Faculty of Life Sciences and Biotechnology South Asian UniversityAkbar BhawanChanakyapuriNew Delhi 110021India The Hormel Institute University of MinnesotaAustinMN55912 USA

Background and aims:Free fatty acids(FFAs)are one of the important regulators of the progression of nonalcoholic fatty liver *** FFAs are shown to modulate the metabolic status of the liver by modulating several cellular pathways in ***,we elucidated the role of miR-22 in modulating FFAs-mediated ***:Huh7 and WRL68 cells were transfected with nonspecific miRNA,miR-22 premiRs or anti-miR-22 oligos followed by incubation with palmitic acid,oleic acid,and linoleic acid(300μM each)for 48 and 72 h after *** expression of miR-22 was performed using real-time polymerase chain reaction and Western blots were performed for SIRT-1,PGC-1α,PEPCK,and *** groups of C57BL/6 mice(6 mice per group)were fed with standard diet,choline sufficient L-amino acid defined diet or choline-deficient L-amino acid defined(CDAA)diet for 6,18,32,or 54 *** content was measured in the *** of miR-22 and the protein expression of gluconeogenic enzymes were analyzed in the tissue ***:Incubation of miR-22-transfected cells with FFAs inhibited the expression of SIRT-1,PGC-1α,PEPCK,and glucose-6-phosphatase,while miR-22 expression was *** changes were reversed when the cells were transfected with anti-miR-22 ***-fed mice showed the significant increase in triglycerides content and miR-22 expression,while there was an inhibition of SIRT-1,PGC-1α,PEPCK,and glucose-6-phosphatase expression in CDAA-fed mice.

关键词： NASH Gluconeogenesis SIRT-1 CSAA CDAA microRNA-22

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