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Epidemiological Characteristics of COVID-19 Confirmed Cases in Muscat Governorate, Sultanate of Oman

Open Journal of Epidemiology 2021年第1期11卷 56-69页

作者： Lamya al Balushi Fatma al Fahdi Thamra al Ghafri Mohammed Amin Jeffrey Singh Balqees al Siyabi Mariam al Kalbani maya al kindi Fatma al Balushi Haleema al Ghazaili Malak al alwai Salwa al Mashari Hanan al kindi Ahlam al Rumhi Ibtisam al Shidhani Zainb al Balushi Padmamohan J. Kurup Fatma al Ajmi Disease Surveillance and Control Directorate General for Health Services Muscat Governorate Ministry of Health Muscat Oman Directorate General for Health Services Muscat Governorate Ministry of Health Muscat Oman Primary Health Care Directorate General for Health Services Muscat Governorate Ministry of Health Muscat Oman Directorate General of Khoula Hospital Muscat Oman Directorate General for Disease Surveillance and Control Ministry of Health Muscat Oman

Introduction: The coronavirus disease 2019 (COVID-19) was declared as pandemic by WHO by March 11th. First case reported in Oman was on 24th February 2020 and later the country went through stages of epidemic progression. This study describes the sociodemographic and epidemiological characteristics of confirmed COVID-19 cases in Muscat governorate and related outcomes. Materials and Methods: This is a descriptive, exploratory analysis of all lab confirmed COVID 19 cases that were reported from 1st February to 31st May 2020. Data for the study was primarily extracted from notifications system established for surveillance (Tarassud). Secondary data sources were, contact listings and hospital medical records. Results: 11,648 initial cases of confirmed COVID-19 infections were included. The mean age was 35 years, 84.7% (N = 9862) were males, 25.9% (N = 3017) were Omanis, and 74.1% (N = 8631) were expatriates of which Indian origin were the majority (37%). Fever and cough were the most common presentations (46.3% and 29.5% respectively). Diabetes and hypertension were the most common comorbidities (4.9% and 4.6% respectively). Hospital admission was required for 7% (N = 811) of the total reported cases, out of them 171 cases (21%) were admitted to ICU, where 107 (13.2%) were ventilated. The case fatality rate (CFR) was 0.9%. 158 clusters containing 2949 contacts were identified from case records and categorised into 3 groups based on their exposure settings. The incubation period measured was 8 days (IQR 4.0 - 15.0) for workplace, 8 days (IQR 4 - 17) for dormitory and 4 days (IQR 2.0 - 7.0) for family groups. The secondary attack rate (SAR) estimated was 41.6% (95% CI: 0.34 - 0.48), 52% (95% CI: 0.40 - 0.63) and 33% (95% CI: 0.27 - 0.38) for workplace, dormitory and family groups, respectively. Conclusion: Results of this study, determine the transmission trend of COVID-19 in a country with high immigran

关键词： COVID-19 Epidemiological Characteristics Infectious Disease Cluster

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Epidemiological Characteristics of COVID-19 Confirmed Cases in Muscat Governorate,Sultanate of Oman

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Open Journal of Epidemiology 2021年第1期

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Green synthesis of bentonite-supported iron nanoparticles as a heterogeneous Fenton-like catalyst:Kinetics of decolorization of reactive blue 238 dye

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Water Science and Engineering 2020年第4期13卷 286-298页

作者： Ahmed Khudhair Hassan Ghayda Yaseen al-kindi Dalal Ghanim Environment and Water Directorate Ministry of Science and TechnologyBaghdad 10070Iraq Sanitary and Environmental Branch Civil Engineering DepartmentUniversity of TechnologyBaghdad 10009Iraq

This study aimed to synthesize green tea nano zero-valent iron(GT-NZVI)and bentonite-supported green tea nano zero-valent iron(BGT-NZVI)nanoparticles using green tea extracts in an environmentally sustainable *** was used as a support material because it disperses and stabilizes GT-NZVI,and it helps to reduce the cost,increase the adsorption capacity of GT-NZVI,and decrease the optimum amount of GT-NZVI used in Fenton-like oxidation.A scanning electron microscope,an atomic force microscope,and a Fourier transform infrared spectroscope were used to characterize GT-NZVI and B-GT-NZVI,while the zeta potential was measured to evaluate the stability of iron *** decolorization kinetics of reactive blue 238(RB 238)dye in the aqueous phase in the Fenton-like oxidation process were investigated as *** effects of various experimental conditions such as reaction time,dosages of catalysts,concentration of H2O2,temperature,addition of inorganic salts,and other parameters were *** results show that the oxidative degradation efficiencies of RB 238 dye catalyzed by GT-NZVI and B-GT-NZVI were 93.5%and 96.2%,respectively,at the optimum reaction conditions as follows:c(H2O2)¼5 mmol/L,r(GT-NZVI)¼0.5 g/L or r(B-GT-NZVI)¼0.5 g/L,c(RB 238 dye)¼0.05 mmol/L,and pH¼2.5 at 180 *** best catalytic performance was exhibited when B-GT-NZVI was *** kinetic models were employed,and the second-order model was found to be the best model representing the experimental kinetic data of RB 238 *** value of activation energy decreased from 38.22 kJ/mol for GT-NZVI to 14.13 kJ/mol for *** indicates that the effect of B-GT-NZVI in decreasing the energy barrier is more pronounced than that of the GT-NZVI catalyst,leading to improved Fenton-like oxidation processes.©2020 Hohai *** and hosting by Elsevier *** is an open access article under the CC BY-NC-ND license(http://***/licenses/by-nc-nd/4.0/).

关键词： Green synthesis Bentonite-supported iron nanoparticles Azo dye Fenton-like process Kinetics

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Incidence and trends of cardiovascular mortality after common cancers in young adults:Analysis of surveillance, epidemiology and end-results program

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World Journal of Cardiology 2016年第6期8卷 368-374页

作者： Sadeer G al-kindi Guilherme H Oliveira Onco-Cardiology Center University Hospitals Seidman Cancer Center and Harrington Heart and Vascular Institute

AIM: To describe the incidence of cardiovascular mortality(CVM) in survivors of major cancers and identify its trends over the past two decades. METHODS: We used the surveillance, epidemiology and end-results 19 registry to identify young adults(20-49 years), diagnosed with the following major primary cancers: Lung, breast, liver/intrahepatic bile duct, pancreas, prostate, colorectal, and ovarian from 1990 through 2012 and identified the cumulative incidence of CVM after adjusting for confounding factors. RESULTS: We identified a total of 301923 cancers(breast 173748, lung 38938, colorectal 31722, prostate 22848, ovary 16065, liver 9444, pancreas 9158). A total of 2297(0.8%) of patients had incident CVM. Lung(10-year cumulative CVM 2.4%) and liver(1.73%) cancers had the highest incidence of CVM, while breast(0.6%) and prostate(1.2%) had the lowest CVM mortality, even after multiple adjustments(P all, there was a significant improvement in CVM since 1990 [2005-2012 vs 1990-1994, adjusted HR 0.63(0.54-0.72), P ally significant improvement in CVM among survivors of colorectal, pancreatic, liver, or prostate ***: The risk of CVM differs among different cancers, and is highest among survivors of lung and liver cancers. The incidence of CVM has decreased over the past 2 decades mainly among survivors of lung and breast cancers.

关键词： Cardiovascular disease Cancer Trends Cardiovascular mortality Type of Cancer

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Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk

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World Journal of Gastroenterology 2010年第27期16卷 34332-3436页

作者： Mansour S al-Moundhri Manal al-Khanbashi Mohammed al-kindi Maryam al-Nabhani Ikram A Burney Abdulaziz al-Farsi Bassim al-Bahrani Medical Oncology Unit Department of MedicineCollege of Medicine and Health SciencesSultan Qaboos University Department of Clinical Genetics College of Medicine and Health SciencesSultan Qaboos University Department of Biochemistry College of Medicine and Health SciencesSultan Qaboos University National Oncology Center Royal Hospital

AIM:To investigate the associations between CDH1 gene polymorphisms and gastric cancer(GC) risk ***:We analyzed four CDH1 polymorphisms(+54 T>C,-160 C>A,-616 G>C,-3159 T>C) in an Omani population,by extraction of genomic DNA from the peripheral blood of 192 patients with GC and 170 control participants and performed CDH1 genotyping using DNA ***:CDH1-160-AA genotype was associated with an increased risk of GC(OR = 3.6,95% CI:1.1-11.8)(P = 0.03).There was no significant association between the other polymorphisms and GC *** haplotype analysis of +54 T>C,-160 C>A,-616 G>C,-3159 T>C genotypes revealed that the OR of CCGC and CAGC haplotypes was 1.5(95% CI:0.7-3.5) and 1.5(95% CI:0.2-3.0),but did not reach statistical ***:The current study suggests that the-160 AA genotype was associated with an increased risk of GC in Oman.

关键词： Gastric cancer Polymorphism CDH1

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NAT2 polymorphism in Omani gastric cancer patients-risk predisposition and clinicopathological associations

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World Journal of Gastroenterology 2007年第19期13卷 2697-2702页

作者： Mansour S al-Moundhri Mohamed al-kindi Maryam al-Nabhani Bassim al-Bahrani Ikram A Burney ali al-Madhani Shyam S Ganguly Misbah Tanira Medical Oncology Unit Department of Medicine College of Medicine and Health Sciences Sultan Qaboos University Sultanate of Oman Department of Biochemistry and Genetics Sultan Qaboos University Sultanate of Oman National Cancer Institute Royal Hospital Sultanate of Oman Department of Medicine Sohar Hospital Sultanate of Oman Department of Epidemiology and Medical Statistics Sultan Qaboos University Sultanate of Oman Department of Pharmacology Sultan Qaboos University Sultanate of Oman

AIM： To study whether N-acetyltransferase 2 （NAT2） genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and to study the clinico-pathological correlations and the prognostic significance of NAT2. METHODS： Genomic DNA was extracted from peripheral blood of 100 gastric cancer patients and 100 control subjects. NAT2 genotyping was performed using DNA sequencing. The prognostic significance of NAT2 and other clinicopathological features was assessed by univariate and multivariate analyses. RESULTS： We observed no significant association between NAT2 genotypes and phenotypes and gastric cancer risk. The IVAT2 phenotype polymorphisms and gastric cancer risk predisposition were not modified by concomitant Hpylori infection and smoking. There was no significant association between NAT2 and clinicopathological features, and NAT2 had no independent prognostic significance. CONCLUSION： In the current study, NAT2 genotypes and phenotypes are not associated with gastric cancer risk predisposition. Moreover NAT2 phenotypes had no clinicopathological associations or prognostic significance.

关键词： Gastric cancer Polymorphism NAT2 Hpylori Arab Omani

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Contemporary characteristics and outcomes of adults with familial dilated cardiomyopathy listed for heart transplantation

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World Journal of Cardiology 2019年第1期11卷 38-46页

作者： Mohamed Khayata Sadeer G al-kindi Guilherme H Oliveira Cardiology Section Department of Internal Medicine University Hospitals Cleveland Medical Center Harrington Heart and Vascular Institute

BACKGROUND Familial dilated cardiomyopathy(FDCM) account for 20%-30% of non-ischemic cardiomyopathies(NICM). Previous published data showed that some patients with FDCM tend to have rapidly progressive disease; however, five-year mortality was not significantly different in the familial and non-familial forms of NICM with optimal medical *** To better define the characteristics and clinical outcomes of FDCM patients listed for heart transplantation(HT).METHODS We queried the United Network for Organ Sharing Registry to identify FDCM patients listed for HT between January 2008 and September 2015 and compared them to NICM and ischemic cardiomyopathy(ICM) patients. We included all patients ≥ 18 years old and we separated patients to three groups: FDCM, NICM and ICM. Chi-square test was used to compare between categorical variables, the t-test was used to compare between continues variables, and Cox-proportional hazards model was used to perform time-dependent survival *** Of the 24809 adults listed for HT, we identified 677 patients(2.7%) with the diagnosis of FDCM. Compared to patients with NICM and ICM, FDCM patients were younger(FDCM 43.9 ± 13.5 vs NICM 50.9 ± 12.3, P al artificial heart(FDCM 1.3% vs NICM 0.6%, P = 0.039; vs ICM 0.4%, P =0.002). Additionally, patients with FDCM were less frequently delisted for clinical deterioration or death and more likely to be transplanted compared to those with NICM [hazard ratio(HR): 0.617, 95% confidence interval(CI): 0.47-0.81; HR: 1.25,95%CI: 1.14-1.37, respectively], and ICM(HR: 0.5, 95%CI: 0.38-0.66; HR: 1.18,95%CI: 1.08-1.3, respectively). There was more frequent rejection among patients with FDCM(FDCM 11.4% vs NICM 9.8%, P = 0.28; vs I

关键词： Familial dilated cardiomyopathy End-stage heart failure Wait list Transplant Outcomes

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The Incidence of Splenic Injury Following Blunt Abdominal Trauma (BAT), Sultan Qaboos University Hospital Experience

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Surgical Science 2017年第7期8卷 312-318页

作者： Abdullah al-Busaidi Tariq al-Shafei Huda al-Moqbali Sara al-kindi Mohammed al-Saadi Nadya al-Busaidi Hani al-Qadhi College of Medicine & Health Sciences Sultan Qaboos University Muscat Sultanate of Oman

The aim of the study was to review traumatic splenic injury following blunt abdominal trauma (BAT), during the period from January 2009 to January 2015 at SQUH. The data for this study was retrospectively collected. It included 768 patients admitted to SQUH general surgery department following BAT. 43 patients with splenic injury were identified (34 males, 9 females). The mean age of patients with splenic injury was 36.0 years (34.4 years for males, 42.1 years for females). The most common mechanism of injury was motor vehicle collision (90.7%). Grade I, II are the most common grades of splenic injury. Non-Omani patients accounted for (51.2%) and most of them were pedestrians at the time of trauma. Ribs fracture is the most common injury associated with splenic injury. 36 (83.7%) patients were managed conservatively and 7 (16.3%) patients were splenectomized. Angioembolization was done for 11 (30.6%) patients. Despite the small population of Oman, high incidence of motor vehicle collision (MVC) increases the incidence of splenic injury among young age group.

关键词： Spleen Splenic Injury Blunt Abdominal Trauma Motor Vehicle Collision

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Critical Technical Awakenings

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Journal of Social Computing 2021年第4期2卷 365-384页

作者： maya Malik Momin M.Malik the School of Social Work McGill UniversityMontréalH3A 0G4Canada the Institute in Critical Quantitative Computational&Mixed MethodologiesJohns Hopkins UniversityBaltimoreMD 21218USA

Starting with Philip ***’s 1997 essay on“critical technical practice”,we consider examples of writings from computer science where authors describe“waking up”from a previously narrow technical approach to the world,enabling them to recognize how their previous efforts towards social change had been *** use these examples first to talk about the underlying assumptions of a technology-centric approach to social problems,and second to theorize these awakenings in terms of Paulo Freire’s idea of critical ***,understanding these awakenings among technical practitioners as examples of this more general phenomenon gives guidance for how we might encourage and guide critical awakenings in order to get more technologists working effectively towards positive social change.

关键词： critical technical practice critical consciousness perspective transformation education machine learning

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Open Journal of Epidemiology 2021年第2期11卷 135-151页

作者： Fatma al Fahdi Padmamohan J. Kurup Lamya al Balushi Mohammed Amin Balqees al Siyabi Mariam al Kalbani Haleema al Ghazaili Salwa al Mashari Hanan al kindi Disease Surveillance and Control Directorate General of Health Services Muscat Governorate Ministry of Health Muscat Oman Directorate General of Disease Surveillance & Control Ministry of Health Muscat Oman Primary Health Care Directorate General of Health Services Muscat Governorate Ministry of Health Muscat Oman

Introduction: The coronavirus disease 2019 epidemic emerged in December 2019 and spread worldwide. Since workplaces are high-risk location for occupational exposure, understanding of the dynamics of COVID-19 clusters... 详细信息

align="justify"> Introduction: The coronavirus disease 2019 epidemic emerged in December 2019 and spread worldwide. Since workplaces are high-risk location for occupational exposure, understanding of the dynamics of COVID-19 clusters in occupational settings helps reduce the transmission of infectious disease in workplaces. This study presents an overview of the epidemiological characteristics of COVID-19 workplace clusters, preventive strategies adopted and outbreak responses undertaken in Muscat governorate. Materials and Methods: This is a descriptive study on the epidemiological characteristics of cases and distribution of workplace-related clusters of COVID-19 in Muscat Governorate in Oman. Results: A total of 36,798 COVID-19 cases were confirmed in Muscat from 24th February to 31st July 2020 in which 40.5% was belonging to clusters. Out of them 61% were Workplace-Dormitory clusters, predominantly expatriates. 78.6% of employees were symptomatic at time of examination. Fever and cough were the two most common symptoms reported in workplace related clusters. The number of affected employees ranged from 2 to 358 per cluster. Construction, retail, food, beverages, services, industrial manufacturing, oil & gas and transportation were identified as most at risk settings. Within the cases in workplace-related clusters, there was significant higher prevalence of diabetes, hypertension and obesity among females compared to males as also Omani nationals compared to expatriates and smoking among expatriate males compared to Omani males. In conclusion, understanding the epidemiological characteristics of the affected cases in organization setting will assist the policymakers to understand patterns of epidemiological spread and plan for robust interventions. <

关键词： COVID-19 Epidemiology Clusters Occupational Workplace Dormitories

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