检索结果-南通市图书馆

The Relationship between Serum 25-Hydroxyvitamin D and Resistin Levels in Saudi Diabetic Patients

Open Journal of.Endocrine and Metabolic Diseases 2016年第2期6卷 102-108页

作者： Ahmed El-Tahir Abdulaziz f. AL-Kaabbab Muaawia Ahmed Hamza Abdullah A. Saeed Abdulshakour Abdalla may f. almohareb Hana S. Alf.leh Gwiria M. H. Satti f.culty of.Medicine King Fahad Medical City Ministry of Health Kingdom of Saudi Arabia f.culty of.Medicine Al-Imam Mohammed Ibn Saud Islamic University Kingdom of Saudi Arabia f.culty of.Medicine University of Khartoum Sudan

Objectives: The aim of.this study was to investigate the relationship between the levels of.25-hydroxyvitamin D and the adipokine resistin in Saudi diabetic patients and those at high risk to develop atherosclerotic cardiovascular diseases. Methodology: One hundred and sixty seven subjects were recruited f.r the cross-sectional study at King f.had Medical City, Saudi Arabia. Blood samples were analyzed f.r biochemical parameters. Serum 25-hydroxyvitamin D and resistin levels were measured f.r all the participants. Result: f.f.y six type-1, 55 type-2 diabetic patients and 56 healthy controls were recruited. Serum 25-hydroxyvitamin D level in the control group was 44.21 ± 41.80 μg/ml compared to 50.67 ± 35.60 μg/ml in the diabetic group (P = 0.427) with no signif.cant dif.erent between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.628). Resistin level in the control group was 14.00 ± 7.39μg/ml compared to 20.21 ± 16.94 μg/ml in the diabetic group (P ≤ 0.01), no signif.cant dif.erence between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.817). Resistin in those taking vitamin D supplementation was 21.34 ± 18.27 μg/ml;and in those not taking vitamin D supplementation, it was 17.4 ± 11.19 μg/ml;(P = 0.237). There was signif.cant negative correlation between 25-hydroxyvitamin D and resistin in type-2 diabetes mellitus (P ≤ 0.043) and no signif.cant correlation was f.und between vitamin 25 (OH) D and resistin level in type-1 diabetes mellitus (P = 0.538). Blood urea and creatinine showed signif.cant positive correlation with vitamin 25 (OH) D in one hand and resistin level on the other hand. Discussion and Conclusions: Several in vitro and in vivo studies have conf.rmed that the vitamin 25 (OH) D have numerous important f.nctions in the body. The circulating vitamin 25 (OH) D and resistin levels were associated with general inf.ammation in renal diseases. This study showed signif.cant negative correlation between resistin level and vitamin 25

关键词： 25-Hydroxyvitamin D Resistin Diabetes Mellitus Kingdom of.Saudi Arabia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evolution of.blockchain consensus algorithms: a review on the latest milestones of.blockchain consensus algorithms

引用

Cybersecurity 2024年第3期7卷 80-101页

作者： Ziad Hussein may A.Salama Sahar A.El-Rahman Electrical Engineering Department Faculty of Engineering-ShoubraBenha UniversityCairoEgypt

Blockchain technology has gained widespread adoption in recent years due to its ability to enable secure and trans-parent record-keeping and data transf.r.A critical aspect of.blockchain technology is the use of.consensus algorithms,which allow distributed nodes in the network to agree on the state of.the *** this review paper,we exam-ine various consensus algorithms that are used in blockchain systems,including proof.of.work,proof.of.stake,and hybrid *** go over the trade-of.s and f.ctors to think about when choosing a consensus algorithm,such as energy ef.iciency,decentralization,and *** also look at the strengths and weaknesses of.each algorithm as well as their potential impact on the scalability and adoption of.blockchain technology.

关键词： Blockchain Consensus Proof.of.work Proof.of.stake Decentralization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

碰撞激活诱导的双势阱势能面可以实现9-甲基-8-氧鸟嘌呤-9-甲基腺嘌呤碱基对阳离子自由基的质子转移

引用

Chinese Journal of.Chemical Physics 2024年第2期37卷 330-340,I0022-I0039,I0104页

作者： may Myat Moe 刘剑波美国纽约城市大学皇后学院化学与生物化学系纽约11367 美国纽约城市大学研究生院纽约10016

8-氧鸟嘌呤(OG)是最常见的核碱基氧化损伤,它在复制过程中可以用Hoogsteen的模式与腺嘌呤(A)错误配对.0G.A碱基对不仅可以诱发G·C→T·A的颠换突变,而且由于OG的电离势和氧化电位低于天然DNA碱基更容易受到电离辐射和单电子氧化的影响... 详细信息

8-氧鸟嘌呤(OG)是最常见的核碱基氧化损伤,它在复制过程中可以用Hoogsteen的模式与腺嘌呤(A)错误配对.0G.A碱基对不仅可以诱发G·C→T·A的颠换突变,而且由于OG的电离势和氧化电位低于天然DNA碱基更容易受到电离辐射和单电子氧化的影响,本文报道了[9MOG·9MA]^(·+)碱華对阳离子自由基的形成.和碰撞诱导解离,该碱基对利用9-甲基8-氧鸟嘌呤(9MOG)和9-甲基腺嘌呤(9MA)模拟相对应的核苷酸.实验通过电喷雾产生Cu(Ⅱ)碱基复合物继之以氧化分离产生[9MOG·9MA]^(·+),并使用导向离子束串级质谱仪检测[9MOG·9MA]^(·+)的碰撞诱导解离、通过测量在不同碰撞能量下的解离产物和反应截面,可以得出[9MOG-H]+[9MA+H]^(+)(主要解离通道)和9MOG^(·+)+9MA(次要通道)的0 K解离阈能分别为1.8和1.65 eV.使用密度泛函理论对[9MOG·9MA]^(·+)的结构计算发现其所有重要构象都发生了质子转移生成[9MOG-H]^(·)·[9MA+H]^(+).另一方面,9MOG^(·+)+9MA的解离通道却需要9MOG^(·+)9MA作为中间体.看似矛盾的结果可以用碰撞活化后反应势能面上出现的双重势阱和由此触发的激发态质子转移平衡([9MOG-H]^(·)·[9MA+H]^(+))^(*)→←(9MOG6(·+)·9MA)^(*)来解释.本文实验和理论研究揭示了这种生物学上重要的非规范碱基对如何在氧化和电离损伤时发生解离.

关键词：碱基对阳离子自由基碰撞诱导解离碱基对内质子转移反应势能面电喷雾电离质谱导向离子束散射

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of.lysosomal traf.icking regulator in autophagic lysosome ref.rmation in neurons:a disease perspective

引用

Neural Regeneration Research 2024年第5期19卷 957-958页

作者： Prashant Sharma Jenny Serra-Vinardell Wendy J.Introne may Christine V.Malicdan NIH Undiagnosed Diseases Program Common FundOffice of the DirectorNational Institutes of HealthBethesdaMDUSA Human Biochemical Genetics Section Medical Genetics BranchNational Human Genome Research InstituteNational Institutes of HealthBethesdaMDUSA(Serra-Vinardell JIntrone)

Lysosomes are discrete organelles that act as recycling centers f.r extracellular and intracellular materials,playing a pivotal role in maintaining cellular *** acidic environment,maintained by numerous hydrolytic enzymes,f.cilitates substrate *** in lysosomal processes can lead to abnormal substrate degradation,signif.cantly impacting cellular *** energy-demanding cells,such as post-mitotic neurons,are especially vulnerable to these changes,of.en resulting in neurological ***,a conserved catabolic process,requires extensive lysosomal *** plays a key role in removing unnecessary intracellular components,ensuring cellular homeostasis,and promoting cell survival during stress conditions such as starvation,inf.ction,or cellular damage.

关键词： homeostasis lysosomal removing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Two-Stream Approximation to the Radiative Transf.r Equation:A New Improvement and Comparative Accuracy with Existing Methods

引用

Advances in Atmospheric Sciences 2024年第2期41卷 278-292页

作者： f.Momo TEMGOUA L.Akana NGUIMDO DNJOMO Environmental Energy Technologies Laboratory(EETL) Faculty of SciencesUniversity of YaoundéPO Box 812 YaoundéCameroon Department of.Electrical and Electronic Engineering Faculty of Engineering and TechnologyUniversity of BueaPO Box 63 BueaCameroon

Mathematical modeling of.the interaction between solar radiation and the Earth's atmosphere is f.rmalized by the radiative transf.r equation(RTE), whose resolution calls f.r two-stream approximations among other methods. This paper proposes a new two-stream approximation of.the RTE with the development of.the phase f.nction and the intensity into a third-order series of.Legendre polynomials. This new approach, which adds one more term in the expression of.the intensity and the phase f.nction, allows in the conditions of.a plane parallel atmosphere a new mathematical f.rmulation of.γparameters. It is then compared to the Eddington, Hemispheric Constant, Quadrature, Combined Delta f.nction and Modif.ed Eddington, and second-order approximation methods with ref.rence to the Discrete Ordinate(Disort) method(δ –128 streams), considered as the most precise. This work also determines the conversion f.nction of.the proposed New Method using the f.ndamental def.nition of.two-stream approximation(f.TSA) developed in a previous work. Notably,New Method has generally better precision compared to the second-order approximation and Hemispheric Constant methods. Compared to the Quadrature and Eddington methods, New Method shows very good precision f.r wide domains of.the zenith angle μ 0, but tends to deviate f.om the Disort method with the zenith angle, especially f.r high values of.optical thickness. In spite of.this divergence in ref.ectance f.r high values of.optical thickness, very strong correlation with the Disort method(R ≈ 1) was obtained f.r most cases of.optical thickness in this study. An analysis of.the Legendre polynomial series f.r simple f.nctions shows that the high precision is due to the f.ct that the approximated f.nctions ameliorate the accuracy when the order of.approximation increases, although it has been proven that there is a limit order depending on the f.nction f.om which the precision is lost. This observation indicates that increasing the order of.app

关键词： Radiative Transf.r Equation two-stream method Legendre polynomial optical thickness moments of.specif.c intensity conversion f.nction transmittance ref.ectance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Importance of.Posterior Tibial Slope in TKR: Pre and Post-Operative Measurements in United States Osteoarthritic Patients

引用

Open Journal of.Orthopedics 2024年第8期14卷 374-379页

作者： f.ederick f. Buechel Sr f.ederick f. Buechel Jr Rutgers New Jersey Medical School Department of Orthopaedic Surgery Newark USA Lenox Hill Hospital Department of Orthopaedic Surgery New York USA

Background: Sagittal plane placement of.the tibial component in total knee replacement (TKR) has important implications f.r maximizing the range of.f.exion motion, allowing collateral ligaments to f.nction more normally, as well as providing ideal compressive loading on the tibial bone-prosthesis interf.ce. This study attempts to quantif. the normal posterior tibial slope (PTS) angle pre-operatively and post-operatively in osteoarthritic patients af.er using a conventional extramedullary tibial resection guide to assess its ef.ectiveness. Methods: f.rty-nine primary cementless total knee replacements in 34 osteoarthritic patients were measured radiographically pre-operatively and one year post-operatively to determine the PTS and its ef.ect on range of.motion. Lateral X-rays, using the anterior cortical line of.the tibia, were employed f.r all measurements. Results: Pre-operative PTS measured 11.83˚ (range 5˚ - 18˚), while post-operative PTS of.implanted tibial components measured 11.30o (range 4˚ - 18˚). The pre-operative range of.motion of.112˚ (range 30˚ to 135˚) was improved to 119˚ (range 90˚ to 135˚) post-operatively af.er 1 year. Conclusions: Anterior tibial shaf. ref.rencing using a conventional extramedullary tibial resection guide provides an easy and convenient method f.r reproducing the anatomical PTS during TKR. This methodology provided improvement in average range of.motion f.om 112˚ pre-operatively to 119˚ post-operatively at one year.

关键词： Posterior Tibial Slope Posterior Tibial Inclination Extramedullary Tibial Resection Guide Total Knee Alignment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluating transient behaviour of.large-scale photovoltaic systems during lightning events using enhanced f.nite dif.erence time domain method with variable cell size approach

引用

HIGH VOLTAGE 2024年第3期9卷 636-647页

作者： Hetita, Ibrahim Mansour, Diaa-Eldin A. Han, Yang Yang, Ping Wang, Congling Darwish, Mohamed M. f. Lehtonen, Matti Zalhaf. Amr S. Univ Elect Sci & Technol China UESTC Sch Mech & Elect Engn Chengdu Peoples R China Helwan Univ Fac Engn Elect Power & Machines Engn Dept Cairo Egypt Tanta Univ Fac Engn Elect Power & Machines Engn Dept Tanta Egypt Egypt Japan Univ Sci & Technol Fac Engn Dept Elect Power Engn Alexandria Egypt Benha Univ Fac Engn Shoubra Dept Elect Engn Cairo Egypt Aalto Univ Sch Elect Engn Dept Elect Engn & Automation Espoo Finland GMC Dept Med Srinagar Jammu And Kashm India

Photovoltaic (PV) arrays are usually installed in open areas; hence, they are vulnerable to lightning strikes that can result in cell degradation, complete damage, service disruption, and increased maintenance costs. As a result, it is imperative to develop an ef.ective and ef.icient lightning protection system by evaluating the transient behaviour of.PV arrays during lightning events. The aim is to evaluate the transient analysis of.large-scale PV systems when subjected to lightning strikes using the f.nite dif.erence time domain (f.TD) technique. Transient overvoltages are calculated at various points within the mounting system. To optimise the f.TD method's execution time and make it more suitable f.r less powerf.l hardware, a variable cell size approach is employed. Specif.cally, larger cell dimensions are used in the earthing system and smaller cell dimensions are used in the mounting system. The f.TD method is utilised to calculate the temporal variation of.transient overvoltages f.r large-scale PV systems under dif.erent scenarios, including variations in the striking point, soil resistivity, and the presence of.a metal f.ame. Simulation results indicate that the highest transient overvoltages occur at the striking point, and these values increase with the presence of.a PV metal f.ame as well as with higher soil resistivity. f.rthermore, a comparison is perf.rmed between the overvoltage results obtained f.om the f.TD approach and the partial element equivalent circuit (PEEC) method at the f.ur corner points of.the mounting systems to demonstrate the superior accuracy of.the f.TD method. Besides, a laboratory experiment is conducted on a small-scale PV system to validate the simulation results. The calculated overvoltages obtained f.om the f.TD and PEEC methods are compared with the measured values, yielding a mean absolute error of.5% and 11% f.r the f.TD and PEEC methods, respectively, thereby conf.rming the accuracy of.the f.TD simulation model.

关键词： f.TD METHOD MODEL

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acetabular cup size trends in total hip arthroplasty

引用

World Journal of.Orthopedics 2024年第1期15卷 39-44页

作者： Daniel Patrick McKenna Alex Price Timothy McAleese Darren Dahly Paul McKenna may Cleary Department of.Trauma and Orthopaedics University Hospital WaterfordWaterford X91 ER8EIreland Department of.Epidemiology and Public Health University College CorkCork T12 XF62Ireland

BACKGROUND Total hip arthroplasty(THA)is a common procedure f.r end stage *** learning curve f.r THA is complex and *** of.the most dif.icult skills to master is acetabular *** wish to identif. if.experience in arthroplasty leads to preservation of.more bone *** To investigate if.increasing surgeon experience will predict an ever decreasing acetabular cup *** A retrospective case series of.f.ur attending orthopaedic surgeons was *** uncemented elective total hip arthroplasties since appointment were selected f.r *** size of.acetabular cup used was noted and logistic regression was used to identif. if.a trend to smaller cups *** A total of.1614 subjects were included with a mean age of.64 *** cups were on average 0.18mm smaller per year(95%conf.dence interval-0.25 to-0.11,Pf.r surgeon A,0.02 mm/year f.r surgeon B,0.15 mm/year f.r surgeon C and 0.29 mm/year f.r surgeon *** of.the f.ur surgeons had a more pronounced trend to smaller cups f.r male subjects than their f.male *** We f.und increasing surgeon experience to be associated with an ever-decreasing acetabular cup *** acetabular cup size may act as a surrogate marker of.surgical prof.ciency by virtue of.decreased acetabular reaming.

关键词： Hip Arthroplasty Acetabulum Cup Learning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Macroscopic Traversable Wormholes: Minimum Requirements

引用

International Journal of.Astronomy and Astrophysics 2024年第3期14卷 230-243页

作者： Peter K. f. Kuhf.ttig Department of.Mathematics Milwaukee School of Engineering Milwaukee USA

While wormholes are just as good a prediction of.Einstein’s theory as black holes, they are subject to severe restrictions f.om quantum f.eld theory. To allow f.r the possibility of.interstellar travel, a macroscopic wormhole would need to maintain suf.iciently low radial tidal f.rces. It is proposed in this paper that the assumption of.zero tidal f.rces, i.e., the limiting case, is suf.icient f.r overcoming the restrictions f.om quantum f.eld theory. The f.asibility of.this approach is subsequently discussed by 1) introducing the additional conditions needed to ensure that the radial tidal f.rces can indeed be suf.iciently low and 2) by viewing traversable wormholes as emergent phenomena, thereby increasing the likelihood of.their existence.

关键词： Morris-Thorne Wormholes Traversability Minimum Requirements Stability Compatibility with Quantum f.eld Theory

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

On an Invariant of.Tournament Digraphs

引用

Journal of.Applied Mathematics and Physics 2024年第7期12卷 2711-2722页

作者： Boris f. Melnikov Bowen Liu f.culty of.Computational Mathematics and Cybernetics Shenzhen MSU-BIT University Shenzhen China

To date, it is unknown whether it is possible to construct a complete graph invariant in polynomial time, so f.st algorithms f.r checking non-isomorphism are important, including heuristic algorithms, and f.r successf.l implementations of.such heuristics, both the tasks of.some modif.cation of.previously described graph invariants and the description of.new invariants remain relevant. Many of.the described invariants make it possible to distinguish a larger number of.graphs in the real time of.a computer program. In this paper, we propose an invariant f.r a special kind of.directed graphs, namely, f.r tournaments. The last ones, f.om our point of.view, are interesting because when f.xing the order of.vertices, the number of.dif.erent tournaments is exactly equal to the number of.undirected graphs, also with f.xing the order of.vertices. In the invariant we are considering, all possible tournaments consisting of.a subset of.vertices of.a given digraph with the same set of.arcs are iterated over. f.r such subset tournaments, the places are calculated in the usual way, which are summed up to obtain the f.nal values of.the points of.the vertices;these points f.rm the proposed invariant. As we expected, calculations of.the new invariant showed that it does not coincide with the most natural invariant f.r tournaments, in which the number of.points is calculated f.r each participant. So f.r, we have conducted a small number of.computational experiments, and the minimum value of.the pair correlation between the sequences representing these two invariants that we f.und is f.r dimension 15.

关键词： Graph Directed Graph Tournament ?nvariant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：