检索结果-南通市图书馆

DetEEktor:Mask R-CNN based neural network for energy plant identification on aerial photographs

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

能源与人工智能(英文) 2021年第3期5卷 104-118页

作者： maximilian Schulz Bilel Boughattas Frank Wendel Institute of Energy Economics and Rational Energy Use(IER) University Stuttgart70565 StuttgartGermany

Decentralized renewable energies(RE)represent one of the most important elements for future energy *** an optimal integration,a comprehensive knowledge of the installed RE systems and their characteristics is *** Germany,the’Marktstammdatenregister’(MaStR)gives access to most of this information but has significant deficits in terms of up to date data covering all installed systems,later illustrated using a ground truth data set,and completely neglects some plant types *** thermal *** address this,we developed the novel model’DetEEktor’,with which six different RE plant types can be simultaneously detected and characterized on aerial photographs by means of a Mask R convolutional neural *** first contribution of this paper,we give a detailed overview of the structure,design and data base of the ***,we contribute by demonstrating its capability to attack the lack of knowledge of existing RE systems:Dependent on the plant type,we succeed in detecting 63 to 75%of the existing *** on the ground truth use case,we reduce the number of missing photovoltaic systems in the MaStR by 44%and identify 72%of the existing solarthermal *** to a high RE share use case,we identified an estimated number of about 1,468 photovoltaic(including 18 free-field),1,063 solarthermal,6 biomass and 4 wind power plants missing in the *** conclusion,with our presented’DetEEktor’,we aim to contribute to a more detailed data basis of existing RE systems.

关键词： Instance segmentation Renewable energies Convolutional neuronal networks

Resistance to chemoimmunotherapy in non-small-cell lung cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Drug Resistance 2020年第3期3卷 445-453页

作者： maximilian Johannes Hochmair Respiratory Oncology Unit Vienna North Hospital-Klinik FloridsdorfVienna 1210Austria.

Recent clinical trials evaluating the combination of chemotherapy with immune checkpoint inhibition for the primary treatment of lung cancer showed increased progression-free and overall survival compared with chemotherapy ***,the combination of these two modalities is less than additive and the mechanisms of resistance to this therapeutic intervention are discussed *** far,the conventional biomarkers for immunotherapy,namely programmed death-ligand 1 expression or tumor mutational burden are poor predictors of the efficacy of immunochemotherapy,and the optimal sequence of chemotherapy and immunotherapy has yet to be defined.

关键词： Lung cancer chemotherapy immunotherapy combination pembrolizumab resistance

Seeing through a new lens: exploring the potential of city walking tour videos for urban analytics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2023年第1期16卷 2555-2573页

作者： maximilian C.Hartmann Ross S.Purves Department of Geography University of ZurichZurichSwitzerland

City Walking Tour Videos(CWTVs)are a novel source of Volunteered Geographic Information providing street-level imagery through video sharing platforms such as *** demonstrate that these videos contain rich information for urban analytical applications,by conducting a mobility *** detect transport modes with a focus on active(pedestrians and cyclists)and motorised mobility(cars,motorcyclists and trucks).We chose the City of Paris as our area of interest given the rapid expansion of the bicycle network as a response to the Covid-19 pandemic and compiled a video corpus encompassing more than 66 hours of video *** the detection of street names in the video and placename containing timestamps we extracted and georeferenced 1169 locations at which we summarise the detected transport *** results show high potential of CWTVs for studying urban mobility *** detected significant shifts in the mobility mix before and during the pandemic as well as weather effects on the volumes of pedestrians and *** with the observed increase in data availability over the years we suggest that CWTVs have considerable potential for other applications in the field of urban analytics.

关键词： Street-level imagery city walking tour videos transport modes mobility object detection geolocation

A DIAGONALLY-IMPLICIT TIME INTEGRATION SCHEME FOR SPACE-TIME MOVING FINITE ELEMENTS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computational Mathematics 2019年第3期37卷 360-383页

作者： Randolph E.Bank maximilian S.Metti Department of Mathematics University of CaliforniaSan DiegoLa JollaCA 92093-0112USA Adtile Technologies 11750 Sorrento Valley RoadSan DiegoCA 92121USA

In this paper,we analyze and provide numerical experiments for a moving finite element method applied to convection-dominated,time-dependent partial differential *** follow a method of lines approach and utilize an underlying tensor-product finite element space that permits the mesh to evolve continuously in time and undergo discontinuous reconfigurations at discrete time *** employ the TR-BDF2 method as the time integrator for piecewise quadratic tensor-product spaces,and provide an almost symmetric error estimate for the *** numerical results validate the efficacy of these moving finite elements.

关键词： TR-BDF2 Moving firdte elements Method of characteristics Convection-dominated Moving mesh methods Error analysis

基于模块化教学的高校创新创业课程体系构建策略探索

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

教育教学研究前沿

教育教学研究前沿 2024年第3期2卷 72-75页

作者：马西米利安·施密特索菲·布朗莱比锡孔子学院德国萨克森州04155

随着社会经济的快速发展和科技创新的不断推进,高校创新创业教育已经成为现代教育的重要组成部分。然而,当前高校创新创业课程体系存在一些问题,亟待改革和创新。模块化教学作为一种新型的教学方法,具有灵活性强、适应性广、便于评估等... 详细信息

随着社会经济的快速发展和科技创新的不断推进,高校创新创业教育已经成为现代教育的重要组成部分。然而,当前高校创新创业课程体系存在一些问题,亟待改革和创新。模块化教学作为一种新型的教学方法,具有灵活性强、适应性广、便于评估等优点,可以有效提升高校创新创业课程的教学质量和效果。将其应用在高校创新创业课程体系中,可以为学生提供更具实践性和创新性的学习体验,促进其创新能力和创业精神的培养。因而研究基于模块化教学的高校创新创业课程体系构建策略有重要意义。对此,通过阐述高校创新创业课程体系现状,分析基于模块化教学构建高校创新创业课程体系的意义,在此基础上探究基于模块化教学构建高校创新创业课程体系的策略,以期为高校创新创业教育提供新的思路和方法,推动学生全面发展和社会创新创业能力的提升。

关键词：模块化教学高校创新创业课程体系

A review on current anode materials for rechargeable Mg batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2020年第4期8卷 963-979页

作者： Dajian Li Yuan Yuan Jiawei Liu maximilian Fichtner Fusheng Pan Karlsruhe Institute of Technology Institute for Applied Materials-Applied Materials Physics(IAM-AWP)Hermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany National Engineering Research Center for Magnesium Alloys(CCMG) College of Materials Science and EngineeringChongqing University400044 ChongqingChina Karlsruhe Institute of Technology Institute of Nanotechnology(1NT)Hermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany Helmholtz-Institute Ulm(HIU) Helmholtzstr.1189081 UlmGermany

There is an increasing demand for rechargeable batteries in high-performance energy storage *** current dominating Li-ion batteries are limited by price,resource availability,as well as their theoretical *** that the community has started to explore alternative battery *** a promising multivalent battery type,rechargeable magnesium batteries(RMBs)have attracted increasing attention because of high safety,high volumetric energy density,and low cost thanks to abundant resource of ***,the development of high-performance anodes is still hampered by formation of passivating layers on the Mg ***,dendrites can also grow under certain conditions with pure Mg anodes,which requires further studies for reliable operation window and ***,this review specifically aims to provide an overview on the often overlooked yet very important anode materials of RMBs,with the hope to inspire more attention and research efforts for the achievement of over-all better performance of future RMBs.c 2020 Published by Elsevier *** behalf of Chongqing University.

关键词： Rechargeable Mg batteries Anode materials

Innate immune recognition and modulation in hepatitis D virus infection

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第21期26卷 2781-2791页

作者： Stephanie Jung Sebastian maximilian Altstetter Ulrike Protzer Institute of Virology Technical University of Munich/Helmholtz Zentrum MünchenMunich D-81675Germany German Center for Infection Research(DZIF) Munich Partner SiteMunich D-81675Germany

Hepatitis D virus(HDV)is a global health threat with more than 15 million humans *** treatment options are largely unsatisfactory leaving chronically infected humans at high risk to develop liver cirrhosis and hepatocellular *** is the only human satellite virus *** encodes only two proteins,and requires Hepatitis B virus(HBV)envelope protein expression for productive virion release and spread of the *** HDV could evolve and why HBV was selected as a helper virus remains *** the discovery of Na+-taurocholate co-transporting polypeptide as the essential uptake receptor for HBV and HDV,we are beginning to understand the interactions of HDV and the immune *** HBV is mostly regarded a stealth virus,that escapes innate immune recognition,HBV-HDV coinfection is characterized by a strong innate immune *** RNA sensor melanoma differentiation antigen 5 has been reported to recognize HDV RNA replication and activate innate *** immunity,however,seems not to impair HDV replication while it inhibits *** this review,we describe what is known up-to-date about the interplay between HBV as a helper and HDV’s immune evasion strategy and identify where additional research is required.

关键词： Hepatitis D virus Hepatitis B virus Innate immunity Pathogen-associated molecular pattern molecules Immune evasion Immunosuppression

Screening for pancreatic cancer in individuals with genetic susceptibility

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2023年第3期12卷 421-423页

作者： Robert Grützmann maximilian Brunner Department of General and Visceral Surgery Friedrich-Alexander-University(FAU)Erlangen-NurembergErlangenGermany

Pancreatic cancer is a highly lethal disease with a five-year survival rate of only about 10%(1).Early detection is crucial for improving patient outcomes,but pancreatic cancer is often diagnosed at an advanced stage when treatment options are limited(2).Individuals with a genetic susceptibility to pancreatic cancer,such as those with a strong family history or a genetic mutation associated with the disease,are at higher risk of developing pancreatic cancer than the general *** these high-risk individuals could potentially lead to earlier detection and improved outcomes.

关键词： Pancreatic cancer screening genetic susceptibility guideline BRCA

Update on acute myeloid leukemia stem cells:New discoveries and therapeutic opportunities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2016年第10期8卷 316-331页

作者： maximilian Stahl Tae Kon Kim Amer M Zeidan Section of Hematology Department of Internal MedicineYale School of Medicine

The existence of cancer stem cells has been wellestablished in acute myeloid leukemia. Initial proof of the existence of leukemia stem cells(LSCs) was accomplished by functional studies in xenograft models making use of the key features shared with normal hematopoietic stem cells(HSCs) such as the capacity of self-renewal and the ability to initiate and sustain growth of progenitors in vivo. Significant progress has also been made in identifying the phenotype and signaling pathways specific for LSCs. Therapeutically, a multitude of drugs targeting LSCs are in different phases of preclinical and clinical development. This review focuses on recent discoveries which have advanced our understanding of LSC biology and provided rational targets for development of novel therapeutic agents. One of the major challenges is how to target the selfrenewal pathways of LSCs without affecting normal HSCs significantly therefore providing an acceptable therapeutic window. Important issues pertinent to the successful design and conduct of clinical trials evaluating drugs targeting LSCs will be discussed as well.

关键词： Leukemia stem cells Cancer stem cells Acute myeloid leukemia Stem cell niche Xenotransplantation Plerixafor NF-κ B C-X-C chemokine receptor type 4