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The roles of Ventralin,Ventralin-like and HCA127 in Xenopus Neural Development

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The Roles of Ventralin,Ventralin-like and HCA127 in Xenopus ...

A Possible Periodicity in the radio Light Curves of 3C 454.3

中国遗传学会“发育、遗传和疾病”研讨会

作者： Qinghua Kong Bingyu Mao max-Planck Junior Scientist Group on Developmental Biology,Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming 650223,China

Vertebrate neural plate is induced from the ectoderm and then patterned along anterior-posterior and dorsal-ventral axes by different signaling *** is a novel gene specifically expressed in the Xenopus ventral neural tube screened out by large scale whole-mount in situ *** ventralin related gene,named ventralin-like,shows very similar expression patterns with *** XVentralin specific morpholino was injected into one side of the embryos,the embryos curved to the injected sides and have defects in eye development,suggesting potential roles of ventralin in neural and eye *** encodes a 417 amino acids protein with a ring-finger domain at its C-terminus, which is characteristic of a family of ubiquitin e3 *** identify the potential target proteins of ventralin,we performed yeast two hybrid screens using ventralin or ventralin-like as the bait and a Xenopus embryonic cDNA *** hepatocellular carcinoma-associated antigen 127(HCA-127)was isolated by both ventralin and ventralin-like and their interactions were confirmed by ***127 is well conserved among species and is co-expressed with ventralin in the nervous system during Xenopus early *** of function of Xenopus HCA127 by morpholino injection leads to similar phenotype as ventralin morpholino,namely curved body,shortened and ventrally bent tail,and also eye development defect,indicating potential fun(?)tional interactions of the two *** studies have revealed new players in the patterning of vertebrate neural tube and eye development.

关键词： The roles of Ventralin,Ventralin-like and HCA127 in Xenopus Neural Development HCA

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Chinese Journal of Astronomy and Astrophysics 2007年第3期7卷 364-374页

作者： Shan-Jie Qian N. A. Kudryavtseva S. Britzen T. e Krichbaum Long Gao A. Witzel J. A. Zensus M. e Aller H. D. Aller Xi-Zhen Zhang National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 max-Planck-institut ftir radioastronomie Auf dem HUgel 69 53121 Bonn Germany Astronomy Department University of Michigan Ann Arbor MI 48109 USA Astronomical Institute of St.-Petersberg State University Petrodvoretz St.-Petersburg Russia International max-Planck research School for radio and Infrared Astronomy at the Universities of Bonn and Cologne

During the period 1966.5-2006.2 the 15 GHz and 8 GHz light curves of 3C 454.3 （z = 0.859） show a quasi-periodicity of ,-12.8 yr （-6.9 yr in the rest frame of the source） with a double-bump structure. This periodic behaviour is interpreted in terms of a rotating double-jet model in which the two jets are created from the black holes of a binary system and rotating with the period of the orbital motion. The periodic variations in the radio fluxes of 3C 454.3 are suggested to be mainly due to the lighthouse effects （or the variation in Doppler boosting） of the precessing jets caused by the orbital motion. In addition, variations in the rate of mass accreting onto the black holes may be also involved.

关键词： radio continuum galaxies - Quasars individual 3C 454.3

共振光泵X射线激光的抽运谱线和吸收谱线波长匹配实验

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物理学报 1996年第2期45卷 205-209页

作者：范品忠 e.FILL 中国科学院上海光学精密机械研究所 max-Planck-Institut fur Quantenoptik Garching85748 Germany

用octadecyl hydrogen maleate(OHM)晶体谱仪进行了4.5nm附近如下三组共振光泵X射线激光的抽运谱线和吸收谱线对波长匹配实验研究:SiXⅡ3d—2p,4.4021nm,MgX2s—4p,4.4050nm;CuXIX4f—3d, 4.7329nm,MgX2p—4d,4.7310nm;和AIXI3p—2s,4.8... 详细信息

关键词： X射线激光抽运谱线吸收谱线波长匹配

Influence of zone formation on stability of continuous fluidized bed layering granulation with external product classification

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Particuology 2015年第6期13卷 1-7页

作者： C. Dreyschultze C. Neugebauer S. Palis A. Buck e. Tsotsas S. Heinrich A. Kienle Otto yon Guericke University Universit~tsplatz 2 D-39106 Magdeburg Germany max Planck Institute for Dynamics of Complex Technical Systems Sandtorstraabe 1 D-39106 Magdeburg Germanyc Hamburg University of Technology Denickestrae 15 D-21073 Hamburg Germany

Continuous fluidized bed layering granulation with external product classification and a sieve-mill cycle can show instability in the form of self-sustained nonlinear oscillations of the particle size distribution. In the present study, the stability and bifurcation analysis of this process is presented. The underlying process models explicitly account for compartmentalization of the fluidized bed into a granulation and a drying zone, which is an important feature of many technical processes. Implications for plant operations are discussed with the help of stability diagrams as a function of zone size, residence time within different zones, the addition of external seeds and particular properties of the sieve-mill cycle.

关键词： Fluidized bed Granulation Population balance Stability Bifurcation

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低能电子在外层导电屏蔽的玻璃锥管中的传输

物理学报 2017年第12期66卷 107-114页

作者：钱立冰李鹏飞靳博靳定坤宋光银张琦魏龙牛犇万成亮周春林 Arnold Milenko Müller max Dobeli 宋张勇杨治虎 reinhold Schuch 张红强陈熙萌兰州大学核科学与技术学院兰州730000 中国核动力研究设计院成都610005 eTH Swiss Federal Institute of Technology 中国科学院近代物理研究所兰州730000 Physics Department Stockholm University

采用新的具有常数锥角的玻璃锥管,并对玻璃锥管进行了外表面导电屏蔽,通过对电子穿越玻璃锥管的二维角分布随时间演化的观测,研究了低能电子与玻璃管相互作用的机制.发现电子穿越完全放电的玻璃锥管时穿透率先下降后平稳,整个过程中角... 详细信息

采用新的具有常数锥角的玻璃锥管,并对玻璃锥管进行了外表面导电屏蔽,通过对电子穿越玻璃锥管的二维角分布随时间演化的观测,研究了低能电子与玻璃管相互作用的机制.发现电子穿越完全放电的玻璃锥管时穿透率先下降后平稳,整个过程中角分布中心发生微小移动,但角分布的半高宽几乎保持不变.这与我们之前发表的工作(2016 Acta ***.65 204103)不同,这是由于对玻璃锥管进行外表面导电屏蔽会阻止外界不确定的快速充放电的影响,并形成了新的稳定放电通道,有利于实现电子的稳定穿透.电子的穿透率随倾角呈类似矩形的分布,透射电子的角分布中心伴随倾角的变化而移动,其穿透所容许的倾角与几何穿透一致.

关键词：电子导电效应玻璃管

An Improved Convolutional Neural Network Model for DNA Classification

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Computers, Materials & Continua 2022年第3期70卷 5907-5927页

作者： Naglaa.F.Soliman Samia M.Abd-Alhalem Walid el-Shafai Salah eldin S.e.Abdulrahman N.Ismaiel el-Sayed M.el-rabaie Abeer D.Algarni Fathi e.Abd el-Samie Department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadhSaudi Arabia Department of electronics and electrical Communications engineering Faculty of Electronic EngineeringMenoufia UniversityMenoufia32952Egypt Department of Computer Science and engineering Faculty of Electronic EngineeringMenoufia UniversityMenoufia32952Egypt

recently,deep learning(DL)became one of the essential tools in bioinformatics.A modified convolutional neural network(CNN)is employed in this paper for building an integratedmodel for deoxyribonucleic acid(DNA)*** any CNN model,convolutional layers are used to extract features followed by max-pooling layers to reduce the dimensionality of features.A novel method based on downsampling and CNNs is introduced for feature *** downsampling is an improved form of the existing pooling layer to obtain better classification *** two-dimensional discrete transform(2D DT)and two-dimensional random projection(2D rP)methods are applied for *** convert the high-dimensional data to low-dimensional data and transform the data to the most significant feature ***,there are parameters which directly affect how a CNN model is *** this paper,some issues concerned with the training of CNNs have been *** CNNs are examined by changing some hyperparameters such as the learning rate,size of minibatch,and the number of *** and assessment of the performance of CNNs are carried out on 16S rrNA bacterial *** results indicate that the utilization of a CNN based on wavelet subsampling yields the best trade-off between processing time and accuracy with a learning rate equal to 0.0001,a size of minibatch equal to 64,and a number of epochs equal to 20.

关键词： DNA classification CNN downsampling hyperparameters DL 2D DT 2D rP

Fe Nanoclusters on the Ge（001） Surface Studied by Scanning Tunneling Microscopy, Density Functional Theory Calculations and X-ray Magnetic Circular Dichroism

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Nano research 2011年第10期4卷 971-978页

作者： Olaf LUbben Sergey A. Krasnikov Alexei B. Preobrajenski Barry e. Murphy Igor V. Shvets Centre for research on Adaptive Nanostructures and Nanodevices （CrANN） School of Physics Trinity College Dublin Dublin 2 Ireland max-lab Lund University Box 118. 22100 Lund Sweden

The growth of Fe nanoclusters oN the Ge（001） surface has been studied using low-temperature scanning tunneling microscopy （STM） and density functional theory （DFT） calculations. STM results indicate that Fe nucleates on the Ge（001） surface, forming well-ordered nanoclusters of uniform size. Depending on the preparation conditions, two types of nanoclusters were observed having either four or sixteen Fe atoms within a nanocluster. The results were confirmed by DFT calculations. Annealing the nanoclusters at 420 K leads to the formation of nanorow structures, due to cluster mobility at such temperature. The Fe nanoclusters and nanorow structures formed on the Ge（001） surface show a superparamagnetic behaviour as measured by X-ray magnetic circular dichroism.

关键词： Ge(001) iron nanoclusters self-assembly scanning tunnelling microscopy X-ray magnetic circular dichroism density functional theory calculations

Automated high-throughput Wannierisation

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npj Computational Materials 2020年第1期6卷 1091-1108页

作者： Valerio Vitale Giovanni Pizzi Antimo Marrazzo Jonathan r.Yates Nicola Marzari Arash A.Mostofi Cavendish Laboratory Department of PhysicsUniversity of Cambridge19 JJ Thomson AvenueCambridgeUK Departments of Materials and Physics and the Thomas Young Centre for Theory and Simulation of MaterialsImperial College LondonLondon SW72AZUK Theory and Simulation of Materials(THeOS)and National Centre for Computational Design and Discovery of Novel Materials(MArVeL) École Polytechnique Fédérale de LausanneLausanneSwitzerland Department of Materials University of OxfordParks RoadOxford OX13PHUK

maximally-localised Wannier functions(MLWFs)are routinely used to compute from first-principles advanced materials properties that require very dense Brillouin zone integration and to build accurate tight-binding models for scale-bridging *** the same time,high-throughput(HT)computational materials design is an emergent field that promises to accelerate reliable and cost-effective design and optimisation of new materials with target *** use of MLWFs in HT workflows has been hampered by the fact that generating MLWFs automatically and robustly without any user intervention and for arbitrary materials is,in general,very *** address this problem directly by proposing a procedure for automatically generating MLWFs for HT *** approach is based on the selected columns of the density matrix method and we present the details of its implementation in an AiiDA *** apply our approach to a dataset of 200 bulk crystalline materials that span a wide structural and chemical *** assess the quality of our MLWFs in terms of the accuracy of the band-structure interpolation that they provide as compared to the band-structure obtained via full first-principles ***,we provide a downloadable virtual machine that can be used to reproduce the results of this paper,including all first-principles and atomistic simulations as well as the computational workflows.

关键词： generating high details

Analysis of the Interface between Primary and Secondary Metabolism in Catharanthus roseus Cell Cultures Using ^13C-Stable Isotope Feeding and Coupled Mass Spectrometry

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Molecular Plant 2013年第2期6卷 581-584页

作者： Carla Antonio Natali r. Mustafa Sonia Osorio Takayuki Tohge Patrick Giavalbco Lothar Willmitzer Heiko rischer Kirsi-Marj Oksman-Caldentey robert Verpoorte Alisdair r. Fernie Central Metabolism Group Max Planck Institute of Molecular Plant Physiology Am Muehlenberg 1 D-14476 Potsdam-Golm Germany Natural Products Laboratory Institute of Biology Leiden University Einsteinweg 55 2300 RA Leiden The Netherlands Present address: Departamento de Biologia Molecular y Bioquimica Universidad de M.~laga 29071 M=~laga Spain Genes and Small Molecules Group Max Planck Institute of MolecularPlant Physiology Am Muehlenberg 1 D-14476 Potsdam-Golm Germany VTT Technical research Centre of Finland PO Box 1000 F1-02044 VTT (Espoo) Finland

Dear editor, The tropical plant Madagascar periwinkle Catharanthus roseus （L.） *** is a rich source of plant-derived medicinal ter-penoid indole alkaloids （TIAs）, including the anti-hypertensive ajmalicine, the sedative compound serpentine, and the anti-cancer drugs vinblastine and vincristine. However, the latter two compounds are produced in C. roseus plants only in very low amounts. elicitors such as hormones （e.g. jasmonates or salicylic acid） activate plant natural defense responses, includ-ing increased secondary metabolite production （eI-Sayed and Verpoorte, 2007; Lackman et al.. 2011）.

关键词： GAS-CHrOMATOGrAPHY BIOSYNTHeSIS ArABIDOPSIS