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Journal of Integrative Agriculture 2024年第3期23卷 876-887页

作者： Liyao Su Min Wu Tian Zhang Yan Zhong Zongming(max) Cheng State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjing210095China

Rosa roxburghii fruit is rich in flavonoids, but little is known about their biosynthetic pathways. In this study, we employed transcriptomics and metabolomics to study changes related to the flavonoids at five different stages of R. roxburghii fruit development. Flavonoids and the genes related to their biosynthesis were found to undergo significant changes in abundance across different developmental stages, and numerous quercetin derivatives were identified. We found three gene expression modules that were significantly associated with the abundances of the different flavonoids in R. roxburghii and identified three structural UDP-glycosyltransferase genes directly involved in the synthesis of quercetin derivatives within these modules. In addition, we found that RrBEH4, RrLBD1 and RrPIF8could significantly increase the expression of downstream quercetin derivative biosynthesis genes. Taken together,these results provide new insights into the metabolism of flavonoids and the accumulation of quercetin derivatives in R. roxburghii.

关键词： Rosa roxburghii quercetin derivatives weighted gene co-expression network analysis transcription factor transcriptome metabolome

Enabling heterogeneous catalysis to achieve carbon neutrality: Directional catalytic conversion of co_(2) into carboxylic acids

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Carbon Energy 2024年第3期6卷 1-35页

作者： Xiaofei Zhang Wenhuan Huang Le Yu max García-Melchor Dingsheng Wang Linjie Zhi Huabin Zhang KAUST Catalysis Center(KCC) King Abdullah University of Science and Technology(KAUST)ThuwalSaudi Arabia Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and TechnologyXi'anChina State Key Lab of Organic-Inorganic composites Beijing University of Chemical TechnologyBeijingChina School of Chemistry CRANN and AMBERResearch CentresTrinity College DublinCollege GreenDublinIreland Department of Chemistry Tsinghua UniversityBeijingChina Advanced Chemical Engineering and Energy Materials Research Center China University of Petroleum(East China)QingdaoChina

The increase in anthropogenic carbon dioxide(co_(2))emissions has exacerbated the deterioration of the global environment,which should be controlled to achieve carbon *** to the core goal of achieving carbon neutrality is the utilization of co_(2) under economic and sustainable ***,the strong need for carbon neutrality has led to a proliferation of studies on the direct conversion of co_(2) into carboxylic acids,which can effectively alleviate co_(2) emissions and create high-value *** purpose of this review is to present the application prospects of carboxylic acids and the basic principles of co_(2) conversion into carboxylic acids through photo-,electric-,and thermal *** attention is focused on the regulation strategy of the activity of abundant catalysts at the molecular level,inspiring the preparation of high-performance *** addition,theoretical calculations,advanced technologies,and numerous typical examples are introduced to elaborate on the corresponding process and influencing factors of catalytic ***,challenges and prospects are provided for the future development of this *** is hoped that this review will contribute to a deeper understanding of the conversion of co_(2) into carboxylic acids and inspire more innovative breakthroughs.

关键词： carbon neutrality carboxylic acids co_(2)conversion heterogeneous catalyst in situ technology

A study on wildfire impacts on greenhouse gas emissions and regional air quality in South of Orléans,France

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Journal of Environmental Sciences 2024年第1期135卷 521-533页

作者： Chaoyang Xue Gisèle Krysztofiak Yangang Ren Min Cai Patrick Mercier Frédéric Le Fur corinne Robin Benoit Grosselin Véronique Daele max RMcGillen Yujing Mu Valéry Catoire Abdelwahid Mellouki Laboratoire de Physique et Chimie de l’Environnement et de l’Espace(LPC2E) CNRS–UniversitéOrléans–CNES(UMR 7328)Orléans Cedex 245071France Institut de combustion AérothermiqueRéactivitéEnvironnement(ICARE)CNRSOrléans Cedex 245071France Research Centre for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Lig’Air-Association de surveillance de la qualitéde l’air en région Centre-Val de Loire Saint-Cyr-en-Val 45590France Mohammed V University RabatMorocco

Wildfire events are increasing globally which may be partly associated with climate change,resulting in significant adverse impacts on local,regional air quality and global *** September 2020,a small wildfire(burned area:36.3 ha)event occurred in Souesmes(Loiret-Cher,Sologne,France),and its plume spread out over 200 km on the following day as observed by the MODIS *** on measurements at a suburban site(~50 km northwest of the fire location)in Orléans and backward trajectory analysis,young wildfire plumes were *** increases in gaseous pollutants(co,CH_(4),N_(2)O,VOCs,etc.)and particles(including black carbon)were found within the wildfire plumes,leading to a reduced air *** factors,defined as EF(X)=ΔX/Δco(where,X represents the target species),of various trace gases and black carbon within the young wildfire plumes were determined accordingly and compared with previous *** in the ambient ions(such as ammonium,sulfate,nitrate,chloride,and nitrite in the particle-and gasphase)and aerosol properties(e.g.,aerosol water content,aerosol p H)were also quantified and ***,we estimated the total carbon and climate-related species(e.g.,co_(2),CH_(4),N_(2)O,and BC)emissions and compared them with fire emission *** biomass burning emission inventories have uncertainties in estimating small fire burned areas and *** instance,we found that the Global Fire Assimilation System(GFAS)may underestimate emissions(e.g.,co)of this small wildfire while other inventories(GFED and FINN)showed significant *** that it is the first time to record wildfire plumes in this region,related atmospheric implications are presented and discussed.

关键词： Wildfire Air quality Emission factor Emission inventory VOLTAIRE supersite

Data democracy–increased supply of geospatial information and expanded participatory processes in the production of data

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International Journal of Digital Earth 2015年第9期8卷 679-693页

作者： max Craglia Lea Shanley European commission Joint Research CentreIspraItaly Gaylord Nelson Institute for Environmental Studies University of WisconsinMadisonWIUSA

The global landscape in the supply,co-creation and use of geospatial data is changing very rapidly with new satellites,sensors and mobile devices reconfiguring the traditional lines of demand and supply and the number of actors *** this paper we chart some of these technology-led developments and then focus on the opportunities they have created for the increased participation of the public in generating and contributing information for a wide range of uses,scientific and *** all this information is open or geospatial,but sufficiently large portions of it are to make it one of the most significant phenomena of the last *** fact,we argue that while satellite and sensors have exponentially increased the volumes of geospatial information available,the participation of the public is transformative because it expands the range of participants and stakeholders in society using and producing geospatial information,with opportunities for more direct participation in science,politics and social action.

关键词： citizen science volunteered geographic information geospatial data

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谦逊可人的优雅

潇洒 2006年第11期 76-83页

作者： max&co

如果你拥有一种天生的知性气质,那么再结合楚楚的衣着,就能很好的把女性的柔美动人展露出来。这样的你,也许会显得无所不知,但也会是谦逊可人。这是一种非传统的折中主义,服装的魅力,让大家在你的身上找到许多或许是矛盾的元素,却又显... 详细信息

如果你拥有一种天生的知性气质,那么再结合楚楚的衣着,就能很好的把女性的柔美动人展露出来。这样的你,也许会显得无所不知,但也会是谦逊可人。这是一种非传统的折中主义,服装的魅力,让大家在你的身上找到许多或许是矛盾的元素,却又显得么和谐可爱……

关键词：折中主义性气质

Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS

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Journal of Pharmaceutical Analysis 2020年第3期10卷 233-239页

作者： max Sauter Philipp Uhl Jürgen Burhenne Walter E.Haefeli Department of Clinical Pharmacology and Pharmacoepidemiology Heidelberg University HospitalIm Neuenheimer Feld 41069120HeidelbergGermany

Exenatide is the first approved glucagon-like peptide 1 receptor agonist subcutaneously or intramuscularly injected for the treatment of type 2 diabetes *** therapeutic plasma concentrations are in the low pg/mL range,therefore requiring ultra-sensitive *** enable the accurate evaluation of pharmacokinetic studies,we established a UPLC-MS/MS assay with a lower limit of quantification(LLOQ)of 5 pg/mL(1.2 pM)using 200μL of plasma,validated acco rding to FDA's and EMA's pertinent *** was isolated from plasma with solid phase extraction utilizing anionexchange *** was performed with positive electrospray ionization tandem mass spectrometry in the selected reaction monitoring *** calibrated concentration range of 5-10,000 pg/mL was linear showing co rrelation coefficients>*** and intraday accuracy ranged from 97.5%to 105.4%with corre sponding precision ofcorresponding precision ofconcentrations and pharmacokinetics after intravenous and nasal administration to beagle dogs.

关键词： Exenatide Nasal Intravenous UPLC Tandem mass spectrometry Pharmacokinetics

Simulator coupled with Distributed co-Simulation Protocol for Automated Driving Tests

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Automotive Innovation 2021年第4期4卷 373-389页

作者： max-Arno Meyer Lina Sauter Christian Granrath Hassen Hadj-Amor Jakob Andert Teaching and Research Area Mechatronics in Mobile Propulsion RWTH Aachen UniversityAachenGermany FEV Software and Testing Solutions SAS TrappesFrance

To meet the challenges in software testing for automated vehicles,such as increasing system complexity and an infinite number of operating scenarios,new simulation methods must be ***-loop simulations for automated driving(AD)require highly complex simulation models for multiple controlled vehicles with their perception systems as well as their surrounding *** the realization of such models,different simulation domains must be coupled with ***,widely supported model integration standards such as functional mock-up interface(FMI)lack native support for distributed platforms,which is a key feature for AD due to the computational intensity and platform exclusivity of certain *** newer FMI companion standard distributed co-simulation protocol(DCP)introduces platform coupling but must still be used in conjunction with AD *** part of an assessment framework for AD,this paper presents a DCP compliant implementation of an interoperable interface between a 3D environment and vehicle simulator and a co-simulation platform.A universal Python wrapper is implemented and connected to the simulator to allow its control as a DCP slave.A C-code-based interface enables the co-simulation platform to act as a DCP master and to realize cross-platform data exchange and time synchronization of the environment simulation with other integrated models.A model-in-the-loop use case is performed with the traffic simulator CARLA running on a Linux machine connected to the co-simulation master xMOD on a Windows computer via *** virtual vehicles are successfully controlled by cooperative adaptive cruise controllers executed outside of *** standard compliance of the implementation is verified by exemplary connection to prototypic DCP solutions from 3rd party *** exemplary application demonstrates the benefits of DCP compliant tool coupling for AD simulation with increased tool interoperability,reuse potential,and per

关键词： Distributed co-simulation protocol co-simulation Automated driving Traffic simulation Tool coupling

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约会平安夜

潇洒 2006年第12期 38-39页

作者： WENDY max&co LANCEL bally

平安夜就像中国的情人节一样,许多情侣都会在这时逛街,吃饭,看电影等都是他们必不可少节目,如何你才能紧紧地抓住他的眼光?我们精心为你推荐的几款浪漫搭配,让他的眼里只有你。

关键词：平安夜女人味中裤上受生户系带

Temporal and Spatial Effects on Some Physiological Parameters of the Bivalve <i>Lithophaga lithophaga</i>(Linnaeus, 1758) from coastal Regions of Alexandria, Egypt

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Open Journal of Ecology 2014年第12期4卷 732-743页

作者： eman Hashem Radwan Sherifa Shaker Hamed Gaber Ahmed Saad Department of Zoology Faculty of Science Alexandria University Alexandria Egypt Department of Zoology Faculty of Science Damnhour University El Behara Egypt Department of Zoology College of Science King Saud University Saudi Arabia KSA Department of Biology College of Medicine Dammam University Saudi Arabia KSA

The date clam, Lithophaga lithophaga is a popular edible bivalve. It was collected from three different locations (Abo-Quir, Miami and El-Mex) along the coast of Alexandria-Egypt to determine the effect of two heavy metals as copper (Cu) and cadmium (Cd). The three organs were selected: gill, mantle and digestive gland. The enzymatic change is correlated with the concentration of metals. The present results suggest that Miami water is less polluted with Cu and Cd as compared to the two other locations. The physicochemical parameters are not significant among the three locations. Water of Abu-Quir and El-max may be hazardous to bivalves. The order of levels of Cu and Cd was: gill > digestive gland > mantle. The present study illustrated that, in Abu Quir, there was a high positive correlation between Cd and Succinate dehydrogenase (SDH) as r = 0.969 whereas Cu and SDH as r = -0.91.

关键词： Lithophaga lithophaga Heavy Metals Cu Enzyme Activities

超声处理改善羊乳理化性质及其酶凝胶流变学特性

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食品科学 2021年第17期42卷 84-90页

作者：张书文 eman Saad RAGAB 张雨萌王童逄晓阳芦晶蒋士龙冷友斌吕加平中国农业科学院农产品加工研究所北京100193 黑龙江飞鹤乳业有限公司黑龙江哈尔滨150030

在超声频率20 kHz,超声功率800 W,超声时间15、20、25、30 min的条件下处理生羊乳,分析超声处理对羊乳粒径、Zeta-电位、表面疏水性和二级结构的影响,并通过流变学分析和扫描电子显微镜观察进一步研究添加凝乳酶对羊乳酶凝胶的流变学特... 详细信息

在超声频率20 kHz,超声功率800 W,超声时间15、20、25、30 min的条件下处理生羊乳,分析超声处理对羊乳粒径、Zeta-电位、表面疏水性和二级结构的影响,并通过流变学分析和扫描电子显微镜观察进一步研究添加凝乳酶对羊乳酶凝胶的流变学特性和微观结构的影响。结果表明,超声处理降低了羊乳样品的粒径,使蛋白质的二级结构发生明显变化,β-折叠和无规卷曲相对含量增加,α-螺旋和β-转角相对含量降低,β-折叠结构相对含量与表面疏水性呈正相关(r=0.74)。与对照组(未处理的生羊乳和巴氏杀菌羊乳)相比,较长时间(超过20 min)超声处理能显著提高最大储能模量(G’max)(P<0.05),但超声处理25、30 min的羊乳凝乳时间缩短。扫描电子显微镜结果显示超声处理羊乳样品的凝胶微观结构更加致密。综上,超声处理可以有效改善羊乳酶凝胶品质,在实际生产中具有潜在的应用价值。

关键词：羊乳超声处理凝乳酶诱导凝胶流变学微观结构