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The mechanisms of color production in black skin versus red skin on the heads of New World vultures

Avian Research 2023年第1期14卷 86-92页

作者： Nicholas M.justyn matthew j.powers Geoffrey E.Hill Kayla Alexander Adrián Naveda-Rodríguez Scott A.Rush Department of Biological Sciences Auburn UniversityAuburnALUSA College of Veterinary Medicine Mississippi State UniversityMississippiStateMSUSA Department of Wildlife Fisheriesand AquacultureMississippi State UniversityMississippi StateMSUSA

A determination of how the color of animal integument is produced is a starting point for investigations into the function and evolution of *** mechanisms that give rise to the color of bare skin of New World vultures are largely ***,we investigate the source of color production in the bare skin of Turkey Vultures(Cathartes aura)and Black Vultures(Coragyps atratus).Using UV-vis reflectance spectroscopy,we found evidence that hemoglobin is the primary pigment responsible for the red coloration of the bare skin on the heads of Turkey Vultures,and that eumelanin is responsible for the black coloration of the bare skin on the heads of Black *** microscopy of incisional skin samples further supported these mechanisms of color production by revealing the presence of numerous blood vessels near the surface of the Turkey Vulture skin,and a high concentration of melanosomes in the skin of Black *** high performance liquid chromatography(HPLC),we detected carotenoids within the skin of both species with significantly higher total concentrations of carotenoids in the skin of Turkey Vultures compared to the skin of Black *** carotenoids detected were dietary carotenoids that typically produce yellow coloration when accumulated in integument and were present in low *** hypothesize that the dietary carotenoids present do not contribute to the color of the skin,but rather help to compensate for the lack of melanosomes found in Turkey Vulture *** presence of additional carotenoids may act as an antioxidant to minimize UV damage when the bare Turkey Vulture head skin is exposed to direct sunlight for prolonged periods of time when soaring and scavenging for food.

关键词： Carotenoids Cathartes aura Coragyps atratus Hemoglobin High performance liquid chromatography Melanosomes Skin biopsies

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Expression analysis of abscisic acid(ABA) and metabolic signalling factors in developing endosperm and embryo of barley

Expression analysis of abscisic acid(ABA) and metabolic sign...

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2013全国植物生物学大会

作者： CHEN Zhiwei HUANG jianhua Nira MUTTUCUMARU Stephen j.powers Nigel G.HALFORD Biotechnology Research Institute Shanghai Academy of Agricultural Sciences Plant Biology and Crop Science Department Rothamsted Research Computational and Systems Biology Department Rothamsted Research

The expression of genes encoding components of the ABA and metabolic signalling pathway in developing barley endosperm and embryo was *** genes included HvRCAR3547387 and HvRCAR352538(e

关键词： Hordeum vulgare L. abscisic acid(ABA) seed development signalling

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The 10th Antarctic Meteorological Observation,Modeling,and Forecasting Workshop

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Advances in Atmospheric Sciences 2016年第5期33卷 I0001-I0003页

作者： Steve R.COLWELL Arthur M.CAYETTE matthew A.LAZZARA jordan G.powers David H.BROMWICH john j.CASSANO Scott CARPENTIER British Antarctic Survey CambridgeUnited Kingdom Space and Naval Warfare System Center Office of Polar Programs North Charleston SCUSA Antarctic Meteorological Research Center Space Science and Engineering Center University of Wisconsin-Madisonand Department of Physical SciencesSchool of Arts and SciencesMadison Area Technical CollegeMadison WIUSA National Center for Atmospheric Research Boulder COUSA Polar Meteorology Group Byrd Polar&Climate Research CenterThe Ohio State UniversityColumbus OHUSA Cooperative Institute for Research in Environmental Sciences and Department of Atmospheric and Oceanic Sciences University of Colorado-BoulderBoulder COUSA Bureau of Meteorology HobartTasmaniaAustralia

1. Overview The 10th Antarctic Meteorological Observation, Modeling, and Forecasting Workshop （hereinafter AMOMFW） took place june 17-19, 2015 in the historic city of Cambridge, United Kingdom. The meeting followed its purpose of connecting Antarctic atmospheric science to weatherrelated operational issues and advances in observing, modeling, forecasting, and understanding the Antarctic environment.

关键词： AMRC Modeling

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The 16th Workshop on Antarctic Meteorology and Climate and 6th Year of Polar Prediction in the Southern Hemisphere Meeting

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Advances in Atmospheric Sciences 2022年第3期39卷 536-542页

作者： David H.BROMWICH matthew A.LAZZARA Arthur M.CAYETTE jordan G.powers Kirstin WERNER john j.CASSANO Steven R.COLWELL Scott CARPENTIER Xun ZOU Byrd Polar and Climate Research Center The Ohio State UniversityColumbusOhio 43210USA Antarctic Meteorological Research Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWisconsin 53704USA Department of Physical Sciences Madison Area Technical CollegeMadisonWisconsin 53706 USA Naval Information Warfare Center CharlestonSouth Carolina 29406USA National Center for Atmospheric Research BoulderColorado 53706USA Year of Polar Prediction(YOPP)International Coordination Office Alfred Wegener InstituteHelmholtz Centre for Polar and Marine ResearchBremerhaven 27570Germany National Snow and Ice Data Center Cooperative Institute for Research in Environmental Sciences and Department of Atmospheric and Oceanic SciencesUniversity of ColoradoBoulderColorado 80309USA British Antarctic Survey Cambridge CB30ETUnited Kingdom Bureau of Meteorology Hobart 7001Australia

1. Overview In june 2021, the 16th Workshop on Antarctic Meteorology and Climate (WAMC) and the 6th Year of Polar Prediction in the Southern Hemisphere (YOPP-SH) Meeting (http://***/WAMC;021/) were held online and hosted by the Polar Meteorology Group at Byrd Polar and Climate Research Center, The Ohio State University, Columbus,Ohio (Fig. 1).

关键词： Antarctic Hemisphere Climate

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The 13th and 14th Workshops on Antarctic Meteorology and Climate

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Advances in Atmospheric Sciences 2020年第5期37卷 423-430页

作者： matthew A.LAZZARA Sophie A.ORENDORF Taylor P.NORTON jordan G.powers David H.BROMWICH Scott CARPENTIER john j.CASSANO Steven R.COLWELL Arthur M.CAYETTE Kirstin WERNER Antarctic Meteorological Research Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWI 53706USA Department of Physical Sciences School of Arts and SciencesMadison Area Technical CollegeMadison WI 53704USA Department of Atmospheric Sciences University of Wisconsin-MadisonMadisonWI 53706USA National Center for Atmospheric Research Boulder CO 53706USA Polar Meteorology Group Byrd Polar&Climate Research CenterThe Ohio State UniversityColumbus OH 43210USA Bureau of Meteorology HobartTasmania 7001Australia Cooperative Institute for Research in Environmental Sciences and Department of Atmospheric and Oceanic Sciences University of ColoradoBoulderCO 80309USA British Antarctic Survey Cambridge CB30ETUnited Kingdom Naval Information Warfare Center CharlestonSC 29406USA Year of Polar Prediction(YOPP)International Coordination Office Alfred Wegener InstituteHelmholtz Centre for Polar and Marine ResearchBremerhaven 27570Germany

*** In july 2018,the Antarctic community came together to meet at the 13th Workshop on Antarctic Meteorology and Climate(WAMC)in Madison,Wisconsin,USA(Fig.1);and in the following year in june 2019,the 14th WAMC was held in Charleston,South Carolina,USA(Fig.2).With a growing history,the WAMC addresses the topics of Antarctic meteorology and climate(Kameda et al.,2008;Colwell et al.,2016;Lazzara et al.,2018)as well as weather-related issues of scientific and operational *** workshops bring together researchers,operational forecasters,numerical modelers,observational specialists,and *** themes of both workshops included Antarctic meteorological observations,Antarctic atmospheric numerical modeling,Antarctic meteorological and climate research,and Antarctic weather forecasting and operational *** 2018 and 2019 WAMC were both followed by a one-day focus on the Year of Polar Prediction-Southern Hemisphere(YOPP-SH),when preparations and follow-up discussions were made with regard to the YOPP Special Observing Period from 16 November 2018 to 15 February 2019.

关键词： Antarctic weather meteorological

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A homozygous nonsense mutation in DNAjC30 causes Leber’s hereditary optic neuropathy with Leigh-like phenotypes

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Genes & Diseases 2023年第4期10卷 1165-1168页

作者： Chao Shen Kitty Wang Wei Li Alvaro Serrano Kelly powers Chengwan Zhang jianjun Chen Miao Sun Department of Systems Biology Beckman Research Institute of City of HopeMonroviaCA 91016USA Division of Medical Genetics Department of PediatricsChildren’s Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Division of Neurology Children’s Hospital Los AngelesLos AngelesCA 90027USA Division of Genomic Medicine Department of Pathology and Laboratory MedicineChildren’s Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA

Nuclear encoded genes can cause early-onset mitochon-dria-related disorders such as Leigh or Leigh-like *** in DNAjC30 have been implicated in mitochondria-related diseases such as Leber’s hereditary optic neuropa-thy(LHON)and Williams syndrome(WS).However,the role of DNAjC30 in disease progression concerning mitochon-drial dysfunction has yet to be fully *** we report a 12-year-old boy with acute dystonia onset at age 10.

关键词： Leigh Leber acute

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SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses

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Genomics, Proteomics & Bioinformatics 2022年第5期20卷 912-927页

作者： Alexandra j.Lee Dallas L.Mould jake Crawford Dongbo Hu Rani K.powers Georgia Doing james C.Costello Deborah A.Hogan Casey S.Greene Genomics and Computational Biology Graduate Program University of PennsylvaniaPhiladelphiaPA 19104USA Department of Microbiology and Immunology Geisel School of Medicine at DartmouthHanoverNH 03755USA Department of Systems Pharmacology and Translational Therapeutics University of PennsylvaniaPhiladelphiaPA 19104USA Wyss Institute for Biologically Inspired Engineering Harvard UniversityBostonMA 02115USA Department of Pharmacology University of Colorado School of MedicineDenverCO 80045USA Center for Health AI University of Colorado School of MedicineDenverCO 80045USA Department of Biochemistry and Molecular Genetics University of Colorado School of MedicineDenverCO 80045USA

Genome-wide transcriptome profiling identifies genes that are prone to differential expression(DE)across contexts,as well as genes with changes specific to the experimental *** genes that are specifically changed in a context of interest from common differentially expressed genes(DEGs)allows more efficient prediction of which genes are specific to a given biological process under ***,common DEGs or pathways can only be identified through the laborious manual curation of experiments,an inordinately time-consuming *** we pioneer an approach,Specific cOntext Pattern Highlighting In Expression data(SOPHIE),for distinguishing between common and specific transcriptional patterns using a generative neural network to create a background set of experiments from which a null distribution of gene and pathway changes can be *** apply SOPHIE to diverse datasets including those from human,human cancer,and bacterial pathogen Pseudomonas *** identifies common DEGs in concordance with previously described,manually and systematically determined common *** molecular validation indicates that SOPHIE detects highly specific but low-magnitude biologically relevant transcriptional ***’s measure of specificity can complement log2 fold change values generated from traditional DE *** example,by filtering the set of DEGs,one can identify genes that are specifically relevant to the experimental condition of ***,these results can inform future research *** scripts used in these analyses are available at https://***/greenelab/*** can access https://***/greenelab/sophie to run SOPHIE on their own data.

关键词： Neural network Transcriptomics Software Differential expression analysis Machine learning

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山水百家言中国园林中的政治几何学

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风景园林 2009年第3期16卷 96-108页

作者：包华石[美] 赵彩君（翻译）不详北京林业大学北京100083

人们通常认为美学、自然科学和社会科学采用的是三种不同的治学方法，但是历史学家认为事情并不总是如此。在数学物理出现之前，人们常常使用几何形式来代表社会或自然秩序。一些佛教宗派认为诸神和人的世界可以用个发散式的等级序列来... 详细信息

人们通常认为美学、自然科学和社会科学采用的是三种不同的治学方法，但是历史学家认为事情并不总是如此。在数学物理出现之前，人们常常使用几何形式来代表社会或自然秩序。一些佛教宗派认为诸神和人的世界可以用个发散式的等级序列来解释，其中包括许多不连续的，具有独特神力的侧面（图01）。主要寺庙的地理分布，甚至修建那些寺庙的贵族的地位层次也效仿这种等级式排列。

关键词：中国园林几何学政治社会科学自然科学治学方法历史学家数学物理

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补充抗氧化剂对急性心脑血管意外的老年病人血浆抗氧化剂水平的影响

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肠外与肠内营养 2010年第4期17卷 218-220,223页

作者：李青史琳娜樊俊 Hilary j.powers 广州市南方医院营养科广东广州510515 广州市南方医院神经外科广东广州510515 Human Nutrition Unit University of Sheffield

目的:观察补充外源性抗氧化剂对急性心脑血管意外老年病人血浆谷胱甘肽过氧化物酶(GSH-Px)的活性、维生素A(VitA)、维生素C(VitC)、维生素E(VitE)和硒(Se)水平的影响。方法:对105例急性心脑血管意外老年病人随机分为试验组(加用抗氧化剂... 详细信息

目的:观察补充外源性抗氧化剂对急性心脑血管意外老年病人血浆谷胱甘肽过氧化物酶(GSH-Px)的活性、维生素A(VitA)、维生素C(VitC)、维生素E(VitE)和硒(Se)水平的影响。方法:对105例急性心脑血管意外老年病人随机分为试验组(加用抗氧化剂)和对照组(服用安慰剂)。两组病人均每天服用1次,连续6周。两组病人在治疗前、治疗后3周和6周,清晨空腹采取肘静脉血3 ml。检测血浆GSH-Px活性、VitA、VitC、VitE和Se的水平变化。结果:治疗3周和6周后,试验组病人血浆GSH-Px活性,VitC、VitE和Se水平较对照组明显升高(P<0.05)。试验组病人治疗6周后VitA水平较对照组明显升高(P<0.05)。结论:对急性心脑血管意外老年病人补充外源性抗氧化剂,可在短时间内增加血浆VitA、VitC、VitE、Se的含量和GSH-Px的活性。

关键词：谷胱甘肽过氧化酶抗氧化剂急性心脑血管意外,老年病人

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美国心脏协会/美国卒中协会急性缺血性卒中血管内治疗早期管理指南(2015年版)

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中国脑血管病杂志 2015年第10期12卷 552-560页

作者： powers Wj Derdeyn CP Biller j 吴川杰薛芳焦力群朱凤水不详郑州大学第一附属医院神经内科 450052 河北医科大学第二附属医院神经内科首都医科大学宣武医院神经外科

自＂急性缺血性卒中早期管理指南2013年版＂发布以来,出现了大量关于急性缺血性卒中血管内治疗的高质量证据[1]。本版更新的指南主要基于2013年以来8项血管内治疗随机临床试验和其他相关数据的分析结果,同时兼顾了2013年指南的证据,并... 详细信息

自＂急性缺血性卒中早期管理指南2013年版＂发布以来,出现了大量关于急性缺血性卒中血管内治疗的高质量证据[1]。本版更新的指南主要基于2013年以来8项血管内治疗随机临床试验和其他相关数据的分析结果,同时兼顾了2013年指南的证据,并非对上版指南后的文献作全面回顾,而是依据最新的证据作出推荐。本指南与既往指南的重叠部分,以本指南的推荐为准。

关键词：缺血性卒中美国心脏协会科学声明卒中治疗动脉卒中治疗神经介入卒中治疗可回收支架

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