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The Use of Far Infrared Treatment Prior to Exercise in Horses: An mfBIA and Acoustic Myography Three Case Study

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Open Journal of Veterinary Medicine 2024年第4期14卷 69-89页

作者： Adrian harrison D.Phil Department for Veterinary and Animal Sciences (IVH) Faculty of Health & Medical Sciences University of Copenhagen K&#248benhavn Denmark

Background: Acute effects of Far Infrared (FIR) treatment in horses are unknown, especially short periods of 30 minutes, as is any effect on such muscle parameters as warm-up balance, overall exercise balance and laterality asymmetries. Aim: This study examines three equine cases in detail to measure any effects of a short period of FIR treatment. Methods: Multi-frequency bioimpedance (mfBIA) and acoustic myography (AMG), non-invasive techniques, were applied pre- and post-treatment with FIR to the back (T5-L4/5) and for *** dorsi and *** medius was recorded during a 15-minute warm-up regimen. mfBIA parameters included extracellular resistance (Re), centre frequency (fc), membrane capacitance (Mc), intracellular resistance (Ri) and phase angle (PA) which indicates level of training and health status. Results: FIR treatment responses for mfBIA parameters were found to be horse-specific and different, whilst in terms of AMG, FIR treatment for 30 minutes had a beneficial effect on overall balance in all three horses (5 out of 6 muscles), and a beneficial effect on the AMG parameter ST (force symmetry) in all three horses (6 out of 6 muscles). An overall improvement for combined balance and ST values for both muscles and all three horses of 86% was noted with FIR treatment, compared to 56% without. Conclusions: This preliminary study of FIR treatment in three horses, has been found to result in an overall improvement in combined balance and ST values for both muscles. FIR has potential as a promising treatment to reduce the risk of warm-up-related injuries in athletic horses.

关键词： Equine FIR Muscle Balance Muscle Force Injury Prevention

A flexible,thin-film microchannel electrode array device for selective subdiaphragmatic vagus nerve recording

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Microsystems & Nanoengineering 2024年第1期10卷 115-128页

作者： Jongcheon Lim Peter A.Zoss Terry L.Powley Hyowon Lee matthew P.Ward Weldon School of Biomedical Engineering Purdue UniversityWest LafayetteINUSA Birck Nanotechnology Center Purdue UniversityWest LafayetteINUSA Center for Implantable Devices Purdue UniversityWest LafayetteINUSA Department of Psychological Sciences Purdue UniversityWest LafayetteINUSA Purdue Institute of Integrative Neuroscience Purdue UniversityWest LafayetteINUSA Indiana University School of Medicine IndianapolisINUSA

The vagus nerve(VN)plays an important role in regulating physiological conditions in the gastrointestinal(GI)tract by communicating via the parasympathetic pathway to the enteric nervous system(ENS).However,the lack of knowledge in the neurophysiology of the VN and GI tract limits the development of advanced treatments for autonomic dysfunctions related to the *** better understand the complicated underlying mechanisms of the VN-GI tract neurophysiology,it is necessary to use an advanced device enabled by microfabrication *** several candidates including intraneural probe array and extraneural cuff electrodes,microchannel electrode array devices can be used to interface with smaller numbers of nerve fibers by securing them in the separate channel *** microchannel electrode array devices to interface teased nerve structures are relatively bulky with thickness around 200µ*** thick design can potentially harm the delicate tissue structures,including the nerve *** this paper,we present a flexible thin film based microchannel electrode array device(thickness:11.5µm)that can interface with one of the subdiaphragmatic nerve branches of the VN in a *** demonstrated recording evoked compound action potentials(ECAP)from a transected nerve ending that has multiple nerve ***,our analysis confirmed that the signals are from C-fibers that are critical in regulating autonomic neurophysiology in the GI tract.

关键词： electrode recording film

Effect of reaction and post-treatment conditions on physico-chemical properties of magnetic iron oxide nano-particles Author links open overlay panel

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Particuology 2024年第8期91卷 155-167页

作者： Masome Moeni Mohamed Edokali matthew Rogers Oscar Cespedes Louey Tliba Tamseela Habib Robert Menzel Ali Hassanpour School of Chemical and Process Engineering Faculty of Engineering and Physical ScienceUniversity of LeedsLeedsLS29JTUK School of Physics and Astronomy Faculty of Engineering and Physical ScienceUniversity of LeedsLeedsLS29JTUK Mechanical Engineering Department University of Engineering&TechnologyLahorePakistan School of Chemistry Faculty of Engineering and Physical ScienceUniversity of LeedsLeedsLS29JTUK

Poor stability and dispersibility,as well as aggregation are considered as major challenges in clinical application of iron oxide nanoparticles(IONPs).Several studies have shown that the synthesis parameters and post-synthesis treatments e.g.,drying methods,have the capability to improve the particles'***,we investigate the combined effect of synthesis and post-treatment parameters on the particle size,stability and magnetism of ***(Fe_(3)O_(4))NPs were prepared via co-precipitation and post-treated using different methods,i.e.(i)freeze dried at-53℃,0.133 mbar for 48 h(liquid nitrogen frozen(LFD)and freezer frozen(FFD)),(ii)vacuum oven dried(VOD)at 60℃for 24 h,and(iii)kept wet colloidal(WET),dispersed in deionized *** Fe_(3)O_(4)NPs’chemical functional groups,size,shape,crystallinity,stability,aggregation,porosity,and magnetic properties were further analysed using different characterisation *** results showed that,while the WET sample had the best stability and significantly less aggregation at different temperatures,amongst post-treated Fe_(3)O_(4)NPs,LFD sample exhibited the best stability(up to 37℃),dispersion and smallest polydispersity ***,all dried NPs had superparamagnetic characteristics,while,LFD Fe_(3)O_(4)NPs had better magnetic properties and stability than other drying methods.

关键词： Iron oxide nanoparticles Co-precipitation Stability Aggregation Magnetic properties

Simultaneous detection of flare-associated kink oscillations and extreme-ultraviolet waves

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Science China(Technological Sciences) 2024年第5期67卷 1592-1601页

作者： LI Dong HOU ZhenYong BAI XianYong LI Chuan FANG matthew ZHAO HaiSheng WANG JinCheng NING ZongJun Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing210023China Yunnan Key Laboratory of the Solar Physics and Space Science Kunming650216China School of Earth and Space Sciences Peking UniversityBeijing100871China National Astronomical Observatories Chinese Academy of SciencesBeijing100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing100049China School of Astronomy and Space Science Nanjing UniversityNanjing210023China Key Laboratory of Modern Astronomy and Astrophysics Ministry of EducationNanjing UniversityNanjing210023China Columbus Academy GahannaOhio43230USA Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China Yunnan Observatories Chinese Academy of SciencesKunming650216China

Kink oscillations,which are frequently observed in coronal loops and prominences,are often accompanied by extreme-ultraviolet(EUV)***,much more needs to be explored regarding the causal relationships between kink oscillations and EUV *** this article,we report the simultaneous detection of kink oscillations and EUV waves that are both associated with an X2.1 flare on 2023 March 03(SOL2023-03-03T17:39).The kink oscillations,which are almost perpendicular to the axes of loop-like structures,are observed in three coronal loops and one *** short loop shows in-phase oscillation within the same period of 5.2 min at three *** oscillation could be triggered by the pushing of an expanding loop and interpreted as the standing kink *** lags are found between the kink oscillations of the short loop and two long loops,suggesting that the kink wave travels in different *** kink oscillations of one long loop and the prominence are possibly driven by the disturbance of the coronal mass ejection(CME),and that of another long loop might be attributed to the interaction of the EUV *** onset time of the kink oscillation of the short loop is nearly same as the beginning of an EUV *** fact demonstrates that they are almost *** EUV wave is most likely excited by the expanding loop structure and shows two *** leading component is a fast coronal wave,and the trailing one could be due to the stretching magnetic field lines.

关键词： coronal loops solar flares solar prominence solar oscillations extreme-ultraviolet wave magnetohydrodynamic

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气候对格林兰岛冰盖不同位置融水的响应

气候对格林兰岛冰盖不同位置融水的响应

Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies

第34届中国气象学会年会

作者：刘永岗 Robert Hallberg Olga Sergienko Bonnie Samuels matthew harrison Michael Oppenheimer 北京大学大气与海洋科学系 Geophysical Fluid Dynamics Lab NOAA Princeton University

＜正＞格林兰岛冰盖在上一次间冰期期间（约11万5千年前）比现在的规模小很多,在未来气候变暖的情景下有可能会产生类似的冰盖融化和缩小。冰盖融化产生的淡水如果注入北大西洋,会抑制深对流和深水的形成,从而减弱大西洋经圈环流（AMOC... 详细信息

＜正＞格林兰岛冰盖在上一次间冰期期间（约11万5千年前）比现在的规模小很多,在未来气候变暖的情景下有可能会产生类似的冰盖融化和缩小。冰盖融化产生的淡水如果注入北大西洋,会抑制深对流和深水的形成,从而减弱大西洋经圈环流（AMOC）。由于大量的向极热量输送是由AMOC完成的,它的减弱对北半球的气候将有很大的影响。冰盖融水常常通过一些宽度很窄的冰流或出水口注入海洋中,而从不同位置注入海洋的淡水可能会作用于不同的深水形成区,或者对同一个深水形成区产生不同程度的抑制作用,最终导致不同位置的冰

关键词：格林兰岛冰盖冰川融水淡水强迫大西洋经圈环流 AMOC 深对流深水形成北欧海

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Neural Regeneration Research 2024年第4期19卷 788-799页

作者： R.Scott Duncan Sean M.Riordan matthew C.Gernon Peter Koulen Department of Ophthalmology School of MedicineUniversity of Missouri Department of Biomedical Sciences School of MedicineUniversity of Missouri

Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human *** have been studied in cellular and animal models as well as in human clinical trials for their therapeutic benefits in several human *** of these include central nervous system(CNS)diseases and dysfunctions such as forms of epilepsy,multiple sclerosis,Parkinson’s disease,pain and neuropsychiatric *** addition,the endogenously produced cannabinoid lipids,endocannabinoids,are critical for normal CNS function,and if controlled or modified,may represent an additional therapeutic avenue for CNS *** review discusses in vitro cellular,ex vivo tissue and in vivo animal model studies on cannabinoids and their utility as therapeutics in multiple CNS *** addition,the review provides an overview on the use of cannabinoids in human clinical trials for a variety of CNS *** and endocannabinoids hold promise for use as disease modifiers and therapeutic agents for the prevention or treatment of neurodegenerative diseases and neurological disorders.

关键词： anandamide cannabidiol cannabinoid endocannabinoid epilepsy multiple sclerosis neurodegeneration neuroprotection tetrahydrocannabinol

A three-dimensional feature extraction-based method for coal cleat characterization using X-ray μCT and its application to a Bowen Basin coal specimen

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 153-166页

作者： Yulai Zhang matthew Tsang Mark Knackstedt Michael Turner Shane Latham Euan Macaulay Rhys Pitchers ARC Training Centre for M3D Innovation Research School of PhysicsAustralian National UniversityCanberraACT2601Australia Department of Materials Physics Research School of PhysicsAustralian National UniversityCanberraACT2601Australia Anglo American Steelmaking Coal BrisbaneQLD4000Australia SCT Operations Pty Ltd. WollongongNSW2500Australia

Cleats are the dominant micro-fracture network controlling the macro-mechanical behavior of *** understanding of the spatial characteristics of cleat networks is therefore important to the coal mining *** fracture networks(DFNs)are increasingly used in engineering analyses to spatially model fractures at various *** reliability of coal DFNs largely depends on the confidence in the input cleat *** of these parameters can be made from image-based three-dimensional(3D)characterization of coal cleats using X-ray micro-computed tomography(m CT).One key step in this process,after cleat extraction,is the separation of individual cleats,without which the cleats are a connected network and statistics for different cleat sets cannot be *** this paper,a feature extraction-based image processing method is introduced to identify and separate distinct cleat groups from 3D X-ray m CT ***(filters)representing explicit cleat features of coal are built and cleat separation is successfully achieved by convolutional operations on 3D coal *** new method is applied to a coal specimen with 80 mm in diameter and 100 mm in length acquired from an Anglo American Steelmaking Coal mine in the Bowen Basin,Queensland,*** is demonstrated that the new method produces reliable cleat separation capable of defining individual cleats and preserving 3D topology after ***-parallel fractures are also identified and separated,which has his-torically been challenging to delineate and rarely reported.A variety of cleat/fracture statistics is measured which not only can quantitatively characterize the cleat/fracture system but also can be used for DFN ***,variability and heterogeneity with respect to the core axis are *** heterogeneity is observed and suggests that the representative elementary volume(REV)of the cleat groups for engineering purposes may be a complex problem requ

关键词： Cleat separation Cleat statistics Feature extraction Discrete fracture network(DFN)modeling

Skeletal stem cells in bone development,homeostasis,and disease

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Protein & Cell 2024年第8期15卷 559-574页

作者： Guixin Yuan Xixi Lin Ying Liu matthew B.Greenblatt Ren Xu The First Affliated Hospital of Xiamen University-ICMRS Collaborating Center for Skeletal Stem Cell State Key Laboratory of Cellular Stress BiologySchool of MedicineFaculty of Medicine and Life SciencesXiamen UniversityXiamen 361005China Xiamen Key Laboratory of Regeneration Medicine Fujian Provincial Key Laboratory of Organ and Tissue RegenerationOrgan Transplantation InstituteSchool of MedicineXiamen UniversityXiamen 361102China Department of Pathology and Laboratory Medicine Weill Cormell Medical CollegeNew YorkNY 10065USA Research Division Hospital for Special SurgeryNew YorkNY10065USA

Tissue-resident stem cells are essential for development and repair,and in the skeleton,this function is fulfilled by recently identified skeletal stem cells(SSCs).However,recent work has identified that SSCs are not monolithic,with long bones,craniofacial sites,and the spine being formed by distinct stem *** studies have utilized techniques such as fluorescence-activated cell sorting,lineage tracing,and single-cell sequencing to investigate the involvement of ssCs in bone development,homeostasis,and *** investigations have allowed researchers to map the lineage commitment trajectory of ssCs in different parts of the body and at different time ***,recent studies have shed light on the characteristics of ssCs in both physiological and pathological *** review focuses on discussing the spatiotemporal distribution of ssCs and enhancing our understanding of the diversity and plasticity of ssCs by summarizing recent discoveries.

关键词： skeletal stem cells bone development endochondral ossification intramembranous ossification lineage tracing

Navigating Silence: A Comprehensive Review of Parental Roles in the Rehabilitation of Children with Hearing Loss

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Open Journal of Pediatrics 2024年第2期14卷 364-378页

作者： Kondwani Hamanjila Marirajan Thiruppathi harrison Phiri Hearing and Speech Rehabilitation Institute Zhejiang Chinese Medical University Hangzhou China Research and Innovation Department Unicaf University Lusaka Zambia Department of Otolaryngology Lusaka ENT Clinic Lusaka Zambia

This narrative literature review delves into the multifaceted realm of parental involvement in the rehabilitation of children with permanent hearing loss. While existing research has made strides in elucidating parental roles in this context, critical gaps persist, necessitating a comprehensive exploration to inform future endeavors. Our review synthesizes a wide array of studies, identifying these gaps and emphasizing the significance of addressing them. Themes emerging from the literature include the varying degrees of parental engagement, the impact of cultural and socio-economic factors, and the challenges faced by families navigating rehabilitation processes. The synthesis of this literature not only highlights the current state of knowledge but also provides a roadmap for future research efforts. By addressing these gaps, we aim to contribute to a more nuanced understanding of parental involvement in the rehabilitation of children with permanent hearing loss, ultimately fostering improved support systems and holistic care for affected families.

关键词： Parental Involvement Rehabilitation Children Permanent Hearing Loss Socioeconomic Factors Cultural Influences