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Modified Atmospheric Packaging and Its Effect on Postharvest Cannabis Quality

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American Journal of Plant Sciences 2024年第3期15卷 222-234页

作者： luke l. Maclaughlin mason T. MacDonald Department of Plant Food and Environmental Sciences Faculty of Agriculture Dalhousie University Halifax NS Canada

Cannabis sativa l. is used as fiber, food, and medicine in several countries. Though it is illegal for recreational use in most of the world, there are some countries that have legalized production and sale. There is a lot of research on production of cannabis, but less so on storage technologies. Cannabis contains several high value compounds, such as cannabinoids and terpenoids, that are susceptible to degradation via light, temperature, and oxygen. Several studies have explored temperature and light, and industry has adjusted accordingly. However, less is known about oxygen-induced degradation. Biochemical studies have demonstrated oxidative degradation of high value compounds, and many producers use some form of modified atmospheric packaging (MAP) for storage. However, the efficacy of MAP is unclear. The objective of this paper is to review our current understanding of MAP in postharvest cannabis storage and identify avenues where additional research is needed.

关键词： Cannabinoids Cannabis sativa Marijuana Nitrogen Packaging Oxidation Postharvest Terpenoids THC

The Decarbonization of Construction—How Can Alkali-Activated Materials Contribute?

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Engineering 2024年第6期37卷 18-21页

作者： John l.Provis susan A.Bernal Zuhua Zhang Department of Materials Science and Engineering University of SheffieldSheffield S13JDUK Paul Scherrer Institut Villigen PSI 5232Switzerland School of Civil Engineering University of LeedsLeeds LS29JTUK School of Materials Sciences and Engineering Tongji UniversityShanghai 201804China

*** and context Enormous emphasis is currently being paid to the decarbonization of the global built environment as a leading priority for the engineering community and related industrial sectors[1].One of the main contributors to the overall emissions footprint of the built environment-and thus a cornerstone of efforts to achieve decarbonization-is the emissions profile of construction materials during their production and *** cement and concrete sector is the largest-volume contributor to the emissions incurred in meeting the world’s construction material needs and is therefore targeted in the discussion of the deep,rapid decarbonization that must be achieved in order to minimize irreversible damage to the Earth and its ecosystems.

关键词： Alkali corners irreversible

Therapeutic Potential of Thunbergia laurifolia *** in Gestational Diabetes Mellitus:Insights from a Rat Model

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Chinese Journal of Integrative Medicine 2024年第9期30卷 788-798页

作者： Sasitorn Kerdsuknirund Arreeya Kosinan Panida Khunkaewla Pakanit Kupittayanant Ratchadaporn Oonsivilai Pattama Tongdee Porntip Nimkuntod susan Wray Sajeera Kupittayanant School of Preclinical Sciences Institute of ScienceSuranaree University of TechnologyNakhon Ratchasima30000Thailand Biochemistry-Electrochemistry Research Unit School of BiochemistryInstitute of ScienceSuranaree University of TechnologyNakhon Ratchasima30000Thailand School of Animal Technology and Innovation Institute of Agricultural TechnologySuranaree University of TechnologyNakhon Ratchasima30000Thailand School of Food Technology Institute of Agricultural TechnologySuranaree University of TechnologyNakhon Ratchasima30000Thailand School of Obstetrics and Gynecology Institute of MedicineSuranaree University of TechnologyNakhon Ratchasima30000Thailand School of Internal Medicine Institute of MedicineSuranaree University of TechnologyNakhon Ratchasima30000Thailand Harris-Wellbeing Preterm Birth Research Centre Department of Women and Children’s Healththe Institute of Lifecourse and Medical SciencesUniversity of LiverpoolLiverpoolUK

Objective:To assess the effects of Thunbergia laurifolia ***(TlE)on gestational diabetes mellitus(GDM)in a rat ***:Thunbergia laurifolin *** were subjected to ethanolic *** vivo study,50 pregnant rats were randomly divided into 5 groups(10 for each):non-GDM group,GDM induced by streptozotocin(STZ,60 mg/kg i.p.),metformin(MET)100 mg/kg,TlE 50,and 500 mg/kg *** was performed on gestation day 7 until term(day 21).The effects of TlE on blood glucose,insulin levels,lipid profiles,liver enzymes,and maternal performances were *** in vitro study,the effect of TlE was examined using the organ bath for uterine force ***:In in vivo study,TlE significantly reduced blood glucose as compared to GDM(Plly increased insulin *** effect was consistent with islets of langerhans ***,the uterine muscular layer displayed a marked increase in fiber area in response to both doses as compared to GDM(Plly,TlE significantly reduced total cholesterol,triglyceride,and alanine transaminase levels(Ply,TlE also led to a notable augmentation in gravid uterus size,live fetuses count,and implantation numbers,while significantly reducing the post-implantation loss rate associated with fetal classification(Plose to those produced by *** in vitro study,TlE exerted a concentration-dependent inhibition of spontaneous uterine contractility(half-maximal inhibition concentration=1.2 mg/l).This inhibitory effect extended to potassium chloride depolarization and oxytocin-mediated *** combined with its major constituent,rosmarinic acid,TlE produced an enhanced inhibitory effect(Plusions:TlE ameliorated blood glucose levels,enhanced uterine muscular structure,and improved maternal and fetal performance in *** also displayed tocolytic *** findings underscore the need for further explor

关键词： myometrium gestational diabetes mellitus tocolytic oxytocin Thunbergia laurifolia l.

Causes of Cretaceous subduction termination below South China and Borneo:Was the Proto-South China Sea underlain by an oceanic plateau?

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Geoscience Frontiers 2024年第2期15卷 100-124页

作者： Suzanna H.A.van de lagemaat licheng Cao Junaidi Asis Eldert l.Advokaat Paul R.D.mason Mark J.Dekkers Douwe J.J.van Hinsbergen Department of Earth Sciences Utrecht UniversityUtrechtthe Netherlands College of Marine Science and Technology China University of GeosciencesWuhanChina Faculty of Science and Natural Resources Universiti Malaysia SabahKota KinabaluMalaysia

The South China,Indochina,and Borneo margins surrounding the South China Sea contain long-lived arcs that became inactive at approximately 85 Ma,even though an embayment of oceanic crust(the‘Proto-South China Sea’)remained in the intervening *** oceanic crust eventually subducted in the Cenozoic below Borneo and the Cagayan arc,while the modern South China Sea opened in its *** investigate the enigmatic cessation of Mesozoic subduction below South China and Borneo,we studied a fragment of oceanic crust and overlying trench-fill sediments that accreted to NW Borneo during the final stages of Paleo-Pacific *** on radiolarian biostratigraphy of cherts overlying the pillow basalts and detrital zircon geochronology of the trench-fill,we constrained the minimum age of the oceanic crust during accretion to 40 *** shows that subduction cessation was not related to ridge *** analysis of pillow basalts revealed an enriched mid-ocean ridge basalt signature comparable to oceanic *** paleomagnetism,we show that this fragment of oceanic crust was not part of the Izanagi Plate but was part of a plate(the‘Pontus’Plate)separated from the Izanagi Plate by a subduction *** on the minimum 40 Ma age of the oceanic crust and its geochemistry,we suggest that Mesozoic subduction below South China and Borneo stopped when an oceanic plateau entered the trench,while the eastern plate margin with the Izanagi Plate remained *** show how our findings offer opportunities to restore plate configurations of the Panthalassa-Tethys junction region.

关键词： Proto-South China Sea Paleomagnetism Geochemistry Borneo Paleo-Pacific Izanagi Plate

Resolving place names in Amdo and Kham:A gazetteer for the Hengduan Mountains region of Southwest China

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植物分类学报 2006年第6期44卷 721-732页

作者： susan l. KEllEY Arnold Arboretum and Harvard University Herbaria 22 Divinity Avenue Cambridge MA 02138-2020 U.S.A.

Perhaps no region on earth presents such a confusing array of place names as does the area made up of the former provinces of Kham and Amdo in historic Tibet (Xizang). Within these areas, cities, towns, villages, mountains, lakes and other geographic features have at least two names applied to them, one Tibetan, the other Chinese. Overlying this indigenous nomenclature are the names applied by outsiders, mostly Europeans, each of whom used their native language to transliterate the names they heard or read from Tibetan or Chinese script, and names in the languages of other ethnic minorities who live within the area. Adding to the confusion are the conflicting “standards” for transliterating Tibetan and Chinese names. To resolve the inconsistencies and uncertainties of place names in this region, a multilingual gazetteer and thesaurus was prepared. The gazetteer-thesaurus was compiled to be used as a tool for correlating the often radically different names assigned to a single place or feature and to provide the geographic coordinates for each. The impetus for this project was the need to assign geographic coordinates to plant specimens collected in the area since the latter part of the 19th century up until the advent and widespread use of Global Positioning System (GPS) receivers in the 1990s. Georeferencing specimens is necessary for plotting the historical distribution of species and for more completely understanding the information contained on specimen labels. Knowing the distribution of plants is important for answering phylogenetic questions, determining local and widespread biogeographical patterns, identifying areas of unusually high diversity or endemism, and determining areas in need of special protection. The value of such a gazetteer, however, extends well beyond the field of botany. It is intended to be of use to anyone with a desire to know the nomenclatural history of places in the area and for pinpointing with a fair degree of accuracy the location

关键词： Tibet (Xizang) Amdo Kham Hengduan Mountains gazetteer biodiversity Geographic Information Systems (GIS) herbarium conservation georeferencing.

Modified Atmospheric Packaging and Its Effect on Postharvest Cannabis Quality

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Role of calpain system in meat tenderness: A review

American Journal of Plant Sciences（美国植物学期刊） 2024年第3期 222页

作者： luke l.Maclaughlin mason T.MacDonald

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Food Science and Human Wellness 2018年第3期7卷 196-204页

作者： Z.F.Bhat James D.Morton susan l.mason Alaa El-Din A.Bekhit Department of Wine Food and Molecular Biosciences Faculty of Agriculture and Life SciencesLincoln UniversityLincoln7647ChristchurchNew Zealand Department of Food Sciences University of OtagoP.O.Box 56Dunedin 9054New Zealand

Aging is a popular method used by meat industry for improving the sensory attributes of *** the advent of many novel technologies,aging has not lost its charm and is still widely used commercially as a post-mortem intervention for *** improves the tenderness of meat through disruption of the muscle structure by intracellular proteolytic *** undergo various molecular changes that cause proteolysis of key myofibrillar and cytoskeletal proteins,disrupting the overall integrity of muscle *** several endogenous proteolytic systems are capable of post-mortem proteolysis,a great body of scientific evidence supports a major role for the calpain *** are intracellular calcium-dependent cysteine proteases found in most *** least three calpains(μ-and m-calpains and calpain 3)and calpastatin,their specific endogenous inhibitor,are found in *** are known to be involved in the proteolysis of functionally relevant structural proteins such as the myofibrillar proteins and cytoskeletal anchorage *** ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death *** review discusses the role and contribution of the calpain system and the factors that influence calpain activity during aging.

关键词： Aging Tenderness Calpains Proteolysis Calpain activity Factors

landscape of global urban environmental resistome and its association with local socioeconomic and medical status

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Science China(life Sciences) 2024年第6期67卷 1292-1301页

作者： Jun Wu Yige Hu Michael H Perlin David Danko Jun lu Manuela Oliveira Johannes Werner Maria M Zambrano Maria A Sierra Olayinka O Osuolale Paweł Łabaj Nicolás Rascovan Nur Hazlin Hazrin-Chong Soojin Jang Haruo Suzuki Marina Nieto-Caballero Bharath Prithiviraj Patrick K H lee Agnieszka Chmielarczyk Anna Różańska Yongxiang Zhao lan Wang Christopher E mason Tieliu Shi Center for Bioinformatics and Computational Biology and the Institute of Biomedical SciencesSchool of Life SciencesEast China Normal UniversityShanghai 200241China Department of Biology Program on Disease EvolutionUniversity of LouisvilleLouisville 40292USA Weill Cornell Medicine New York 10065USA The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine New York 10065USA Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200025China i3S-Instituto de Investiga玢o e Inova玢o em Saúde Universidade do PortoPorto 4050-290Portugal Ipatimup-Instituto de Patologia e Imunologia Molecular da Universidade do Porto Porto 4200-465Portugal Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPorto 4050-290Portugal High Performance and Cloud Computing Group Zentrum für Datenverarbeitung(ZDV)Eberhard Karls University of TübingenW鋍hterstra遝7672074TübingenGermany Corporación Corpogen Research Center Bogotá110311Colombia Applied Environmental Metagenomics and Infectious Diseases Research(AEMIDR) Department of Biological SciencesElizade UniversityIlara-Mokin 340271Nigeria Maopolska Centre of Biotechnology Jagiellonian UniversityKraków 30-005Poland Aix-Marseille Université Mediterranean Institute of OceanologyUniversitéde ToulonCNRSIRDUM 110Marseille 83041France Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangor Institut Pasteur Korea Seoul 13488Republic of Korea Faculty of Environment and Information Studies Keio UniversityFujisawaKanagawa 252-0882Japan University of Colorado at Boulder CivilEnvironmental and Architectural DepartmentBoulder 80303USA Brooklyn College of the City University of New York Brooklyn 11210USA School of Energy and Environment City University of Hong KongHong Kong 999077China Department of Microbiology Faculty of MedicineJagiellonian UniversityKraków 30-005Poland Biological Targeting Diagnosis and The

Antimicrobial resistance(AMR)poses a critical threat to global health and development,with environmental factors—particularly in urban areas—contributing significantly to the spread of antibiotic resistance genes(ARGs).However,most research to date has been conducted at a local level,leaving significant gaps in our understanding of the global status of antibiotic resistance in urban *** address this issue,we thoroughly analyzed a total of 86,213 ARGs detected within 4,728 metagenome samples,which were collected by the Meta SUB International Consortium involving diverse urban environments in 60 cities of 27 countries,utilizing a deep-learning based *** findings demonstrated the strong geographical specificity of urban environmental resistome,and their correlation with various local socioeconomic and medical *** also identified distinctive evolutionary patterns of ARG-related biosynthetic gene clusters(BGCs)across different countries,and discovered that the urban environment represents a rich source of novel *** study provides a comprehensive overview of the global urban environmental resistome,and fills a significant gap in our knowledge of large-scale urban antibiotic resistome analysis.

关键词： urban environment metagenome antibiotic resistance resistance diversity biosynthetic gene clusters

Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes

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Cancer Innovation 2024年第3期3卷 81-94页

作者： Sahil Seth Runzhe Chen Yang liu Junya Fujimoto lingzhi Hong Alexandre Reuben susan Varghese Carmen Behrens Tina McDowell luisa Solis Soto Cara Haymaker Annikka Weissferdt Neda Kalhor Jia Wu Xiuning le Natalie I Vokes Chao Cheng John V.Heymach Don l.Gibbons P.Andrew Futreal Ignacio IWistuba Humam Kadara Jianhua Zhang Cesar Moran Jianjun Zhang Department of Genomic Medicine The University of Texas MD Anderson Cancer CenterHoustonTexasUSA TRACTION The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Graduate School of Biomedical Sciences The University of Texas MD Anderson and the University of Texas Health Science CenterHoustonTexasUSA Department of Thoracic/Head and Neck Medical Oncology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Epidemiology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Pathology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Imaging Physics The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Medicine Baylor College of MedicineHoustonTexasUSA

Background:Pulmonary sarcomatoid carcinoma(PSC)is a rare and aggressive subtype of non-small cell lung cancer(NSClC),characterized by the presence of epithelial and sarcoma-like *** molecular and immune landscape of PSC has not been well ***:Multiomics profiling of 21 pairs of PSCs with matched normal lung tissues was performed through targeted high-depth DNA panel,whole-exome,and RNA *** describe molecular and immune features that define subgroups of PSC with disparate genomic and immunogenic features as well as distinct clinical ***:In total,27 canonical cancer gene mutations were identified,with TP53 the most frequently mutated gene,followed by ***,most TP53 and KRAS mutations were earlier genomic events mapped to the trunks of the tumors,suggesting branching evolution in most PSC *** identified two distinct molecular subtypes of PSC,driven primarily by immune infiltration and *** Immune High(IM-H)subtype was associated with superior survival,highlighting the impact of immune infiltration on the biological and clinical features of localized ***:We provided detailed insight into the mutational landscape of PSC and identified two molecular subtypes associated with ***-H tumors were associated with favorable recurrence-free survival and overall survival,highlighting the importance of tumor immune infiltration in the biological and clinical features of PSCs.

关键词： genomic immune pulmonary sarcomatoid carcinoma survival