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Nano-Micro Letters 2024年第1期16卷 106-130页

作者： Jun Hu Mitsumasa iwamoto Xiangyu Chen CAS Center for Excellence in Nanoscience Beijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 100083People’s Republic of China School of Nanoscience and Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China Department of Physical Electronics Tokyo Institute of Technology2‑12‑1 S3‑33 O‑OkayamaMeguro‑KuTokyo 152‑8552Japan

The triboelectric nanogenerator(TENG)can effectively collect energy based on contact electrification(CE)at diverse interfaces,including solid–solid,liquid–solid,liquid–liquid,gas–solid,and gas–*** enables energy harvesting from sources such as water,wind,and *** this review,we provide an overview of the coexistence of electron and ion transfer in the CE *** elucidate the diverse dominant mechanisms observed at different interfaces and emphasize the interconnectedness and complementary nature of interface *** review also offers a comprehensive summary of the factors influencing charge transfer and the advancements in interfacial modification ***,we highlight the wide range of applications stemming from the distinctive characteristics of charge transfer at various ***,this review elucidates the future opportunities and challenges that interface CE may *** anticipate that this review can offer valuable insights for future research on interface CE and facilitate the continued development and industrialization of TENG.

关键词： Contact electrification Interfaces Triboelectric nanogenerators Diversified applications

Epigenetic memory of drug exposure history controls neural stem cell quiescence in the adult brain

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Neural Regeneration Research 2024年第4期19卷 711-712页

作者： Masakazu iwamoto Taito Matsuda Department of Stem Cell Biology and Medicine Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

Neural stem cells(NSCs)are the source of all neurons and glial cells(astrocytes and oligodendrocytes)in the central nervous *** adult mammalian brain retains NSCs in the subgranular zone of the dentate gyrus in the hippocampus and ventricular subventricular zone lining the lateral ventricle(Olpe and Jessberger,2022).Adult NSCs in rodents are preserved throughout life and continuously produce new neurons that integrate into the pre-existing neuronal network.

关键词： neural integrate continuously

Mechanisms underlying ^(18)F-fluorodeoxyglucose accumulation in colorectal cancer

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World Journal of Radiology 2016年第11期8卷 880-886页

作者： Kenji Kawada masayoshi iwamoto Yoshiharu Sakai Department of Surgery Graduate School of MedicineKyoto University

Positron emission tomography(PET) with ^(18)F-fluorodeoxyglucose(FDG) is a diagnostic tool to evaluate metabolic activity by measuring accumulation of FDG, an analogue of glucose, and has been widely used for detecting small tumors, monitoring treatment response and predicting patients' prognosis in a variety of cancers. However, the molecular mechanism of FDG accumulation into tumors remains to be investigated. It is well-known that most cancers are metabolically active with elevated glucose metabolism, a phenomenon known as the Warburg effect. The underlying mechanisms for elevated glucose metabolism in cancer tissues are complex. Recent reports have indicated the potential of FDG-PET/CT scans in predicting mutational status(e.g., KRAS gene mutation) of colorectal cancer(CRC), which suggests that FDG-PET/CT scans may play a key role in determining therapeutic strategies by non-invasively predicting treatment response to anti-epidermal growth factor receptor(EGFR) therapy. In this review, we summarize the current findings investigating the molecular mechanism of ^(18)F-FDG accumulation in CRC.

关键词： 18 F-fluorodeoxyglucose-positron 排放断层摄影术 Colorectal 癌症葡萄糖新陈代谢 Mutational 地位 KRAS

Simple procedure for assessing diffuse subarachnoid hemorrhage successfully created using filament perforation method in mice

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Animal Models and Experimental Medicine 2024年第1期7卷 77-81页

作者： Tatsushi Mutoh Ryota Tochinai Hiroaki Aono masayoshi Kuwahara Yasuyuki Taki Tatsuya Ishikawa Department of Surgical Neurology Research Institute for Brain and Blood VesselsAkita Cerebrospinal and Cardiovascular CenterAkitaJapan Department of Aging Research and Geriatric Medicine Institute of DevelopmentAging and CancerTohoku UniversitySendaiJapan Department of Veterinary Pathophysiology and Animal Health Graduate School of Agriculture and Life SciencesThe University of TokyoTokyoJapan

The murine model of subarachnoid hemorrhage(SAH)is a valuable experimental tool for investigating molecular and cellular mechanisms,and the endovascular filament perforation technique can be used to simulate prominent pathophysiological features observed after human SAH;however,current validation methods for assessing an appropriate SAH model are ***,we introduce a simple procedure for se-lecting a mouse model of diffuse *** was induced in 24 mice using a standard filament perforation *** confirming survival at 24 h,SAH was scored 0-1 based on T2*-weighted images on whole-brain magnetic resonance imaging(MRI)and visual surveillance of the cisterna magna(CM)through the dura *** CM-based SAH grading correlated well with a reference parameter defined by extracted brain(r^(2)=0.53,p<0.0001).The receiver operating characteristic curve revealed a sensi-tivity of 85%and a specificity of 91%for detecting diffuse SAH,with a similar area under the curve(0.89±0.06[standard error of the mean])as the MRI-based grading(0.72±0.10,p=0.12).Our data suggest that confirming an SAH clot in the CM is a valuable way to select a clinically relevant diffuse SAH model that can be used in future experimental studies.

关键词： cisterna magna clot distribution filament perforation mouse model subarachnoid hemorrhage

Computationally Efficient Large-Eddy Simulation of Periodic Unsteady Flow using Harmonic Balance Method

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Journal of Thermal Science 2022年第1期31卷 62-71页

作者： YUMA iwamoto SUSUMU Teramoto KOJI Okamoto Department of Aeronautics and Astronautics University of TokyoTokyo 113-8656Japan Department of Advanced Energy University of TokyoTokyo 113-8656Japan

To improve the efficiency and fidelity of the numerical analysis for cascade flutter, we propose an efficient scale-resolving simulation method dedicated to time-periodic flows by incorporating the harmonic balance approach into the large-eddy simulation. This method combined convergence calculations of the steady-state problem based on the harmonic balance method for periodic components, and the nonlinear time-marching method for turbulent fluctuations. Using the proposed method, deterministic periodic components and stochastic turbulent fluctuations were calculated simultaneously, and the effect of turbulent fluctuations on deterministic periodic components was directly calculated without using turbulence models. In this paper, we explain the algorithm and feature of this simulation technique and present the results of the computation for channel flow excited in the streamwise direction as an analysis example using the proposed method. In order to validate the proposed method, an analysis of sinusoidally pulsating channel flow at the central friction-velocity Reynolds numbers Rer = 180 was conducted, confirming that the amplitude and phase of the mean velocity oscillation computed by the proposed method were in good agreement with those of the conventional LES. The present calculation achieved an order of magnitude improvement in computational efficiency compared to conventional LES.

关键词： harmonic balance LES turbulent channel flow

Superfunctional high-entropy alloys and ceramics by severe plastic deformation

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Rare Metals 2023年第10期42卷 3246-3268页

作者： Parisa Edalati masayoshi Fuji Kaveh Edalati Department of Life Science and Applied Chemistry Nagoya Institute of TechnologyTajimi507-0071Japan Advanced Ceramics Research Center Nagoya Institute of TechnologyTajimi507-0071Japan WPI International Institute for Carbon-Neutral Energy Research(WPI-I2CNER) Kyushu UniversityFukuoka819-0395Japan Mitsui Chemicals Inc.—Carbon Neutral Research Center(MCI-CNRC)Kyushu UniversityFukuoka819-0395Japan

High-entropy alloys and ceramics containing at least five principal elements have recently received high attention for various mechanical and functional *** application of severe plastic deformation(SPD),particularly the high-pressure torsion method,combined with the CALPHAD(calculation of phase diagram) and first-principles calculations resulted in the development of numerous superfunctional high-entropy materials with superior properties compared to the normal functions of engineering *** article reviews the recent advances in the application of SPD to developing superfunctional high-entropy *** superfunctional properties include(ⅰ) ultrahigh hardness levels comparable to the hardness of ceramics in high-entropy alloys,(ⅱ) high yield strength and good hydrogen embrittlement resistance in high-entropy alloys;(ⅲ) high strength,low elastic modulus,and high biocompatibility in high-entropy alloys,(ⅳ) fast and reversible hydrogen storage in high-entropy hydrides,(ⅴ) photovoltaic performance and photocurrent generation on high-entropy semiconductors,(ⅵ) photocatalytic oxygen and hydrogen production from water splitting on high-entropy oxides and oxynitrides,and(ⅶ)CO_(2) photoreduction on high-entropy *** findings introduce SPD as not only a processing tool to improve the properties of existing high-entropy materials but also as a synthesis tool to produce novel high-entropy materials with superior properties compared with conventional engineering materials.

关键词： Multi-principal element alloys(MPEAs) High-entropy alloys(HEAs) High-entropy ceramics(HECs) High-entropy oxides(HEOs) Ultrafine-grained(UFG)microstructure High-pressure torsion(HPT)

ADAM8 inactivation retards intervertebral disc degeneration in mice

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Genes & Diseases 2024年第3期11卷 91-94页

作者： Zuozhen Tian Frances S.Shofer Mingyue Fan Alec Z.Sandroni Lutian Yao Lin Han Ling Qin Motomi Enomoto-lwamoto Yejia Zhang Department of Physical Medicine&Rehabilitation Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA19146USA Department of Emergency Medicine Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA 19104USA Department of Orthopedic Surgery Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA 19104USA School of Biomedical Engineering Science&Health SystemsDrexel UniversityPhiladelphiaPA 19104USA Department of Orthopedics/Sports Medicine and Joint Surgery the First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Orthopedics University of Maryland School ofMedicineBaltimoreMD21201USA Section of Rehabilitation Medicine Corporal Michael J.Crescenz Veterans Affairs Medical CenterPhiladelphiaPA 19104USA

ADAM8 has been identified as the fibronectin-cleaving enzyme in human degenerative intervertebral disc(IVD)tissues.^(1)Increase of the active form of ADAM8 and its cleavage product,fibronectin fragment,correlated with an increased degree of IVD degeneration.1 Furthermore,fibronectin fragments have been shown to accelerate the progression of IVD degeneration.^(2)These findings suggest that ADAM8 may play a role in degenerative disc disease,a clinical problem with tremendous socioeconomic burdens in the United States.

关键词： ADAM8 degeneration intervertebral

Drug-induced lung injury caused by acetaminophen in a Japanese woman:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9936-9944页

作者： masayoshi Fujii Tsuneaki Kenzaka Department of Internal Medicine Toyooka Public HospitalToyooka 668-8501Japan Department of Internal Medicine Hyogo Prefectural Tamba Medical CenterTamba 669-3495Japan Division of Community Medicine and Career Development Kobe University Graduate School of MedicineKobe 652-0032Japan

BACKGROUND All drugs have the potential to cause drug-induced lung injury both during and after drug *** has been reported to cause druginduced lung injury,although this is extremely ***,we present an extremely rare case of acetaminophen-induced *** SUMMARY A healthy 35-year-old Japanese woman visited a neighborhood clinic with complaints of fever and malaise following a tick *** treatment included1,500 mg acetaminophen(Caronal^(?)) and subsequently minocycline(200 mg) and acetaminophen(2,000 mg;Caronal^(?)) daily when her condition did not improve;the patient was eventually *** patient’s chest computed tomography(CT) revealed consolidation and ground-glass opacities in the right middle and lower *** was shifted to sulbactam/***,her fever did not improve during follow-up,and her chest CT revealed extensive ground-glass opacities in the right middle and lower lobes and thick infiltrative shadows in the bilateral basal ***-induced lung injury was suspected;hence,acetaminophen was *** fever resolved immediately,and inflammatory response and respiratory imaging findings improved.A drug-induced lymphocyte stimulation test was performed against acetaminophen(Caronal^(?)),and significant proliferation of lymphocytes was noted only for acetaminophen(stimulation index,2.1).CONCLUSION Even common drugs such as over-the-counter drugs can cause drug-induced lung damage.

关键词： Acetaminophen Computed tomography Pneumonia Fever Tick bite Case report

A Quantum Tanimoto Coefficient Fidelity for Entanglement Measurement

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IEEE/CAA Journal of Automatica Sinica 2023年第2期10卷 439-450页

作者： Yangyang Zhao Fuyuan Xiao masayoshi Aritsugi Weiping Ding the School of Big Data and Software Engineering Chongqing UniversityChongqing 401331China IEEE the Faculty of Advanced Science and Technology Kumamoto UniversityKumamoto 860-8555Japan the School of Information and Technology Nantong UniversityNantong 223019China

Fidelity plays an important role in quantum information processing,which provides a basic scale for comparing two quantum *** present,one of the most commonly used fidelities is Uhlmann-Jozsa(U-J)***,U-J fidelity needs to calculate the square root of the matrix,which is not trivial in the case of large or infinite density ***,U-J fidelity is a measure of overlap,which has limitations in some cases and cannot reflect the similarity between quantum states ***,a novel quantum fidelity measure called quantum Tanimoto coefficient(QTC)fidelity is proposed in this *** other existing fidelities,QTC fidelity not only considers the overlap between quantum states,but also takes into account the separation between quantum states for the first time,which leads to a better performance of ***,we discuss the properties of the proposed QTC *** fidelity is compared with some existing fidelities through specific examples,which reflects the effectiveness and advantages of QTC *** addition,based on the QTC fidelity,three discrimination coefficients d_(1)^(QTC),d_(2)^(QTC),and d_^(3)^(QTC)are defined to measure the difference between quantum *** is proved that the discrimination coefficient d_(3)^(QTC)is a true ***,we apply the proposed QTC fidelity-based discrimination coefficients to measure the entanglement of quantum states to show their practicability.

关键词： Distance measure entanglement measurement fidelity measure quantum Tanimoto coefficient(QTC) similarity measure uncertainty

Real-Time Iterative Compensation Framework for Precision Mechatronic Motion Control Systems

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IEEE/CAA Journal of Automatica Sinica 2022年第7期9卷 1218-1232页

作者： Chuxiong Hu Ran Zhou Ze Wang Yu Zhu masayoshi Tomizuka State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084 Beijing Key Laboratory of Precision/Ultra-Precision Manufacture Equipments and Control Tsinghua UniversityBeijing 100084China Department of Mechanical Engineering University of CaliforniaBerkeleyCA 94720-1740 USA IEEE

With regard to precision/ultra-precision motion systems,it is important to achieve excellent tracking performance for various trajectory tracking tasks even under uncertain external *** this paper,to overcome the limitation of robustness to trajectory variations and external disturbances in offline feedforward compensation strategies such as iterative learning control(ILC),a novel real-time iterative compensation(RIC)control framework is proposed for precision motion systems without changing the inner closed-loop ***,the RIC method can be divided into two parts,i.e.,accurate model prediction and real-time iterative *** accurate prediction model considering lumped disturbances is firstly established to predict tracking errors at future sampling *** light of predicted errors,a feedforward compensation term is developed to modify the following reference trajectory by real-time iterative *** the prediction and compen-sation processes are finished in a real-time motion control sampling *** stability and convergence of the entire control system after real-time iterative compensation is analyzed for different *** simulation results consistently demonstrate that the proposed RIC framework possesses satisfactory dynamic regulation capability,which contributes to high tracking accuracy comparable to ILC or even better and strong robustness.

关键词： Precision motion control prediction model real-time iterative compensation trajectory tracking