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Evaluation of Patient-Specific Quality Assurance for Carbon Ion Radiotherapy Using Full Energy Scanning Method at QST Hospital

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2022年第4期11卷 200-209页

作者： Asami Inomata masashi katsumata Sung Hyun Lee Yui Suzuki Takeo Nakajima Wataru Furuichi Keishi Yamaoka Atsushi Yamamoto Hideyuki Mizuno Ryosuke Kohno Accelerator Engineering Corporation Chiba Japan Department of Accelerator and Medical Physics National Institutes for Quantum and Radiological Science and Technology Chiba Japan Department of Heavy Particle Medical Science Graduate School of Medical Science Yamagata University Yamagata Japan QST Hospital National Institutes for Quantum and Radiological Science and Technology Chiba Japan Department of Radiological Sciences International University of Health and Welfare Tochigi Japan

Purpose: Patient-specific QA (PSQA) measurements for carbon ion radiotherapy (CIRT) are critical components of processes designed to identify discrepancies between calculated and delivered doses. We report the results of PSQA conducted at the QST Hospital during the period from September 2017 to March 2018. Methods: We analyzed PSQA results for 1448 fields for 10 disease sites with various target volumes, target depths and number of energy layers. For the PSQA, all the planned beams were recalculated on a water phantom with treatment planning software. The recalculated dose distributions were compared with the measured distributions using a 2D ionization chamber array at three depths, including 95% of the area of the prescription dose. These recalculated dose distributions were evaluated using the 3%/3mm gamma index with a passing threshold of 90%. Results: The passing rates for prostate, head and neck, and bone and soft tissue were 96.8%, 99.3%, and 91.7%, respectively. Additionally, 94.7% of lung plans with low energy beams passed. Overall, the CIRT in the QST Hospital reached a high passing rate of more than 95%. Although the remaining 5% failed to pass, there was no dependence between measurement depth and disease sites in these failures. Conclusion: Using PSQA measurements, we confirmed consistency between the planned and delivered doses for CIRT using the full energy scanning method.

关键词： Carbon Ion Radiotherapy Full Energy Scanning Patient-Specific Quality Assurance Gamma Index

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A new electric field mill array with each of the mill’s rotor controlled precisely by a GPS module:Equipment and initial results

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Earth and Planetary Physics 2024年第2期8卷 423-435页

作者： Kozo Yamashita Hironobu Fujisaka DaoHong Wang Hiroyuki Iwasaki Kazuo Yamamoto Koichiro Michimoto masashi Hayakawa Department of Production Systems Engineering and Sciences Komatsu UniversityNu 1-3 Shicho-machiKomatsuIshikawa 923-8511Japan Fujisaka Technology Office 1058-5 Yoshizawa-choOhta-shiGunma 373-0019Japan Department of Electrical Electronic and Computer EngineeringGifu University1-1 YanagidoGifu CityGifu 501-1193Japan Cooperative Faculty of Education Gunma University4-2-Aramaki-machiMaebashiGunma 371-8510Japan Department of Electrical and Electronic Engineering Chubu University1200 Matsumoto-choKasugaiAichi 487-8501Japan Independent Researcher Kosenba Town 2-44-11-406Kawagoe CitySaitama350-0036Japan Advanced Wireless&Communications Research Center The University of Electro-Communications1-5-1 ChofugaokaChofuTokyo 182-8585Japan

We have newly designed an electrostatic sensor,called an electric field mill(EFM),to simplify the estimation of the charge position and charge amount transferred by lightning *** is necessary for this remote estimation of the transferred charge to measure electric field changes caused by charge loss at the time of a lightning strike at multiple *** multiple-station measurement of electric field changes,not only speed but also phase for exposure and shielding of the sensing plates inside each EFM of the array should be synchronized to maintain the sensitivities of the deployed ***,there is no such EFM with specified speed and phase control performance of the rotary ***,we developed a new EFM in which the rotary mechanism was controlled consistently to within 3%error by a GPS *** EFMs had been distributed in the Hokuriku area of Japan during the winter season of 2022-2023 for a test *** we describe the design and a simple calibration method for our new EFM *** analysis method based on the assumption of a simple monopole charge structure is also *** validation,locations of assumed point charges were compared with three-dimensional lightning mapping data estimated by radio observations in the MF-HF *** results indicated the validity to estimate transferred charge amounts and positions of winter cloud-to-ground lightning discharges with our new EFM array.

关键词： lightning electrostatic field electric field mill electric field change

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Regeneration mechanisms and therapeutic strategies for neuromuscular junctions in aging and diseases

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Neural Regeneration Research 2025年第1期20卷 193-194页

作者： masashi Fujitani Abu Md Mamun Tarif Yoshinori Otani Department of Anatomy and Neuroscience Faculty of MedicineShimane UniversityShimaneJapan

The neuromuscular junction(NMJ)is an essential synaptic structure composed of motor neurons,skeletal muscles,and glial cells that orchestrate the critical process of muscle contraction(Li et al.,2018).The typical NMJ structure is classically described as having a“pretzel-like”shape in mice(Figure 1),whereas human NMJs have a smaller,fragmented structure throughout *** NMJs exhibit smaller or fragmented endplates,partial denervation,reduced numbers of synaptic vesicles,abnormal presynaptic mitochondria,and dysfunctional perisynaptic Schwann cells(Alhindi et al.,2022).

关键词： aging structure Figure

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Variations of Atmospheric ELF/VLF Radio Noise Due to Seismogenic Modifications in Tropospheric Conductivity

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Open Journal of Earthquake Research 2024年第2期13卷 113-132页

作者： masashi Hayakawa Alexander P. Nickolaenko Hayakawa Institute of Seismo Electromagnetics Co. Ltd. (Hi-SEM) UEC Alliance Center #521 Tokyo Japan The University of Electro-Communications (UEC) Advanced Wireless & Communications Research Center (AWCC) Chofu-shi Tokyo O.Ya. Usikov Institute for Radiophysics and Electronics National Academy of Sciences of the Ukraine Kharkov Ukraine

We suggest a possible explanation of the influence of pre-seismic activity on the registration rate of natural ELF(extremely low frequency)/VLF(very low frequency) pulses and the changes of their characteristics. The main idea is as follows. The distribution of the electric field around a thundercloud depends on the conductivity profile of the atmosphere. Quasi-static electric fields of a thundercloud decrease in those tropospheric regions where an increase of air conductivity is generated by pre-seismic activities due to emanation of radioactive gas and water into the lower atmosphere. The electric field becomes reduced in the lower troposphere, and the probability decreases of the cloud-to-ground (CG) strokes in such “contaminated” areas. Simultaneously, the electric field grows inside and above the thunderclouds, and hence, we anticipate a growth in the number of horizontal and tilted inter-cloud (or intra-cloud) (both termed as IC discharges) strokes. Spatial orientation of lightning strokes reduces vertical projection of their individual amplitudes, while the rate (median number strokes per a unit time) of discharges grows. We demonstrate that channel tilt of strokes modifies the spectral content of ELF/VLF radio noise and changes the rate of detected pulses during the earthquake preparation phase.

关键词： ELF/VLF Radio Noise Earthquake Precursor Pre-Seismic Modification Conductivity Anomaly in the Lower Atmosphere Radioactive Radon Gases CG Lightning Discharges IC Discharges Cloud-to-Ionosphere Discharge

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Enhancing clinical proficiency through laparoscopic training using Japanese origami

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第3期7卷 102-106页

作者： Shunsuke Furukawa Masatsugu Hiraki Naoya Kimura Ryota Sakurai Ryo Kohata Naohiko Kohya masashi Sakai Akashi Ikubo Ryuichiro Samejima Department of Surgery Japanese Red Cross Society Karatsu Red Cross HospitalSaga847-8588Japan Department of Surgery Saga University Faculty of MedicineSaga849-8501Japan

Objective This study aimed to investigate the clinical efficacy of laparoscopic training using origami,a traditional Japanese papercraft,using laparoscopic forceps to create origami *** In this retrospective study,4 surgeons were randomly divided into 2 groups:The training group,consisting of surgeons 1 and 2,and the non-training group,consisting of surgeons 3 and *** the course of a one-year study period,the training group regularly underwent laparoscopic surgery training with a dry box,wherein they folded a total of 1000 origami cranes using laparoscopic *** non-training group periodically underwent common laparoscopic surgery training of techniques such as suturing and *** surgeon regularly performed the transabdominal preperitoneal approach for inguinal *** training was conducted concurrently with the *** procedure time(peritoneum detachment,mesh placement,and closure of the peritoneum),total operation time(time from peritoneum detachment to closure of the peritoneum),and surgical outcomes were *** The training group showed greater improvement in the total operation time and more stable performance than the non-training ***,the time taken for peritoneum detachment was significantly shorter in the training *** Laparoscopic training using origami has the potential to enhance laparoscopic surgical skills and improve surgical outcomes.

关键词： Laparoscopic surgery Training Dry box Origami

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SPERA Hydrogen System^(TM)by LOHC-MCH Method for Massive Hydrogen Storage and Transportation

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Journal of Environmental Science and Engineering(A) 2024年第2期13卷 50-60页

作者： Yoshimi Okada Kaji Naohiro Osamu Ikeda Kenichi Imagawa Hironori Kawai masashi Nagai Yasuhiro Inoue Frontier Business Division Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan Hydrogen Business Department Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan R&D Center Chiyoda Corporation3-13 Moriya-cho Kanagawa-kuYokohama 2208765Japan Technology Development Department Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan

Expanding the hydrogen energy utilization is essential for decarbonization,and the commercialization of hydrogen energy carrier systems that can“store”and“transport”hydrogen in a large scale is *** organic chemical hydride method incorporates hydrogen atoms into the molecular structure of a LOHC(Liquid Organic Hydrogen Carrier)to store and transport hydrogen in a liquid state under normal temperature and pressure,and is a highly safe method with low business *** has been developing the technology since 2002,completed a pilot demonstration in 2014 and named it the SPERA Hydrogen^(TM) System,and successfully completed an international supply chain demonstration that transports hydrogen from Brunei to Japan in a large scale in 2020,moving to the commercialization ***,Chiyoda is conducting feasibility studies with a number of domestic and foreign companies with the aim of commercializing the system as soon as *** this paper,outline,features,development status and our efforts in commercialization of SPERA HydrogenTM System are introduced.

关键词： Hydrogen carrier LOHC Methylcyclohexane MCH toluene

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Evaluation of Patient-Specific Quality Assurance for Carbon Ion Radiotherapy Using Full Energy Scanning Method at QST Hospital

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology（医学物理学、临床工程、放射肿瘤学） 2022年第4期

作者： asami inomata masashi katsumata sung hyun lee yui suzuki takeo nakajima wataru furuichi keishi yamaoka atsushi yamamoto hideyuki mizuno ryosuke kohno

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Analysis of Commuting Modal Shift in Consideration of Social Interaction of Consciousness for Environment

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Journal of Traffic and Transportation Engineering 2024年第2期12卷 63-80页

作者： masashi Okushima Institute of Technology and Science The University of TokushimaTokushima 770-8506Japan

It is the matter for achievement of the low carbon transport system that the excessive use of private vehicles can be controlled *** only improvement of service level of modes except private vehicle,but also consciousness for environmental problem of individual trip maker is important for eco-commuting *** the other hand,consciousness for environment would be changed by influence of other ***,it is aimed in the study that the structure of decision-making process for modal shift to the eco-commuting mode in the local city is described considering environmental consciousness and social *** the purpose,the consciousness for the environment problem and the travel behavior of the commuter at the suburban area in the local city are investigated by the questionnaire *** covariance structure about the eco-consciousness is analyzed with the database of the questionnaire survey by structural equation *** the result,it can be confirmed with the structural equation model that the individual environmental consciousness is strongly related with the intention of self-sacrifice and is influenced with the local interaction of the individual *** the other hand,the intention of modal shift for the commuting mode is analyzed with the database of the questionnaire *** can be found out that the environmental consciousness is not statistically significant for commuting mode choice with the present poor level of service of public ***,the intention of self-sacrifice for the prevention of the global warming is statistically confirmed as the factor of modal shift with the operation of eco-commuting bus service with the RP/SP integrated estimation *** the result,the multi-agent simulation system with social interaction model for eco consciousness is developed to measure the effect of the eco-commuting *** the purpose,the carbon dioxide emission is estimated based on traffic demand an

关键词： Greenhouse gas emission modal shift structural equation model RP/SP combined estimation multi-agent simulation local interaction small world network consciousness for environment commuting shuttle bus local city

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A Case of Warthin’s Tumor Together with IgG4-Related Sialadenitis

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Open Journal of Pathology 2024年第3期14卷 81-89页

作者： Ryogo Aoki Risa Ito Asuka Ohashi Riyoko Niwa masashi Matsuyama Sachiko Oka Naomi Kawaguchi Toshimasa Sakakima Daichi Kodama Naoki Watanabe Daisuke Okamoto Takafumi Naiki Takuji Tanaka Department of Diagnostic Pathology (DDP) & Research Center of Diagnostic Pathology (RC-DiP) Gifu Municipal Hospital Gifu Japan Department of Central Clinical Laboratory Gifu Municipal Hospital Gifu Japan Department of Hematology Gifu Municipal Hospital Gifu Japan

Warthin’s tumor is the second most frequent neoplasm next to pleomorphic adenoma in the salivary gland. The tumor contains the epithelial oncocyte cells with the presence of rich-mitochondria and their surrounding abundant lymphocytes. A relatively new disease entity of IgG4-related disease frequently occurs in the salivary gland. However, the coexistence of Warthin’s tumor and IgG4-related disease is scarcely observed. We have recently experienced a rare case of Warthin’s tumor with IgG4-related sialadenitis. A 51-year-old man presented to our hospital, complaining of a mass with right submandibular tenderness and spontaneous pain. A computed tomography scan of the cervical region revealed a suspicion of lymph node proliferative disease, including malignant lymphoma. Elevated serum levels of IL-2R: 1843 U/ml (reference value 122 - 496 U/ml), IgG: 3430 mg/dl (reference value 861 - 1747 mg/dl), and IgG4: 3140 mg/dl (reference value 11 - 121 mg/dl) were observed. Other laboratory data showed within normal ranges. The cervical tumor was diagnosed as Warthin’s tumor by the findings of fine-needle aspiration cytology and biopsy examination. Immunohistochemistry revealed numerous IgG4- and IgG-positive cells with fibrosis surrounding the epithelial component of Warthin’s tumor, suggesting IgG4-rerated sialadenitis. Finally, we diagnosed the cervical tumor as Warthin tumor with IgG4-related sialadenitis. This is the second report describing a case of Warthin’s tumor with possible involvement of IgG4-related sialadenitis.

关键词： Warthin’s Tumor Sialadenitis IgG4-Related Disease Immunohistochemistry

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Current perspectives of viral

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World Journal of Gastroenterology 2024年第18期30卷 2402-2417页

作者： Daisuke Usuda Yuki Kaneoka Rikuo Ono masashi Kato Yuto Sugawara Runa Shimizu Tomotari Inami Eri Nakajima Shiho Tsuge Riki Sakurai Kenji Kawai Shun Matsubara Risa Tanaka Makoto Suzuki Shintaro Shimozawa Yuta Hotchi Ippei Osugi Risa Katou Sakurako Ito Kentaro Mishima Akihiko Kondo Keiko Mizuno Hiroki Takami Takayuki Komatsu Tomohisa Nomura Manabu Sugita Department of Emergency and Critical Care Medicine Juntendo University Nerima HospitalNerima 177-8521TokyoJapan Department of Sports Medicine Faculty of MedicineJuntendo UniversityBunkyo 113-8421TokyoJapan

Viral hepatitis represents a major danger to public health,and is a globally leading cause of *** five liver-specific viruses:Hepatitis A virus,hepatitis B virus,hepatitis C virus,hepatitis D virus,and hepatitis E virus,each have their own unique epidemiology,structural biology,transmission,endemic patterns,risk of liver complications,and response to antiviral *** remain few options for treatment,in spite of the increasing prevalence of viral-hepatitiscaused liver ***,chronic viral hepatitis is a leading worldwide cause of both liver-related morbidity and mortality,even though effective treatments are available that could reduce or prevent most patients’*** 2016,the World Health Organization released its plan to eliminate viral hepatitis as a public health threat by the year 2030,along with a discussion of current gaps and prospects for both regional and global eradication of viral ***,treatment is sufficiently able to prevent the disease from reaching advanced ***,future therapies must be extremely safe,and should ideally limit the period of treatment necessary.A better understanding of pathogenesis will prove beneficial in the development of potential treatment strategies targeting infections by viral *** review aims to summarize the current state of knowledge on each type of viral hepatitis,together with major innovations.

关键词： Hepatitis A virus Hepatitis B virus Hepatitis C virus Hepatitis D virus Hepatitis E virus Current perspectives

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