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Influence of the Position of the Fermi Level on an Infrared Active Defect in Irradiated Silicon

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Chinese Physics Letters 1995年第5期12卷 289-292页

作者： SHI Yi WU Fengmei ZHENG Youdou SUEZAWA masashi SUMINO Koji Department of Physics Nanjing UniversityNanjing 210093 Institute for Materials Research Tohoku UniversitySendai 980Japan

Influence of the position of the Fermi level on the infrared active defect,so-called higher order bands(HOB),has been investigated in neutron irradiated silicon by using infrared absorption and Hall-effect measurements at low *** optical excitation and the introduction of thermal donors(TD)effectively alter the position of the Fermi *** optically active behaviors between the HOB and TD^(+) have been *** is suggested strongly that the mechanism of the Fermi level influencing on the HOB is the same as that of the TD^(+).

关键词： Fermi Infrared excitation

Greenhouse gas reduction of co-benefit-type wastewater treatment system for fish-processing industry: A real-scale case study in Indonesia

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Water Science and Engineering 2023年第3期16卷 271-279页

作者： Yoshiteru Hamatani Takahiro Watari masashi Hatamoto Takashi Yamaguchi Tjandra Setiadi Toshihiko Konda Nihon Suido Consultants Co. LtdTokyo 163-1122Japan Department of Civil and Environmental Engineering Nagaoka University of TechnologyNiigata 940-2188Japan Department of Chemical Engineering Hanoi University of Science and TechnologyHanoi 11615Vietnam Department of Science of Technology Innovation Nagaoka University of TechnologyNiigata 940-2188Japan Department of Chemical Engineering Institut Teknologi BandungJl.Ganesa 10Bandung 40132Indonesia

This study examined the application of co-benefit-type wastewater treatment technology in the fish-processing industry. Given that there was a dearth of information on fish-processing industrial wastewater in Indonesia, site surveys were conducted. For the entire fish-processing industry throughout the country, the dissemination rate of wastewater treatment facilities was less than 50%. Using a co-benefit approach, a real-scale swim-bed technology (SBT) and a system combining an anaerobic baffled reactor (ABR) with SBT (ABR–SBT) were installed in a fishmeal processing factory in Bali, Indonesia, and the wastewater system process performance was evaluated. In a business-as-usual scenario, the estimated chemical oxygen demand load and greenhouse gas (GHG) emissions from wastewater from the Indonesian fish-processing industry were 33 000 tons per year and 220 000 tons of equivalent CO_(2) per year, respectively. On the other hand, the GHG emissions in the co-benefit scenarios of the SBT system and ABR–SBT system were 98 149 and 26 720 tons per year, respectively. Therefore, introducing co-benefit-type wastewater treatment to Indonesia’s fish-processing industry would significantly reduce pollution loads and GHG emissions.

关键词： Indonesian fish-processing industry Co-benefit wastewater treatment Greenhouse gas emission mitigation Anaerobic baffled reactor Swim-bed technology

Different Magnetic Resonance Imaging Manifestations of Diabetic Chorea in a Case with Hyperglycemia and Another One with Hypoglycemia

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Case Reports in Clinical Medicine 2018年第3期7卷 220-224页

作者： Hodaka yamada Rika Saikawa Suzuki Daisuke Yuko Matsumoto masashi Yoshida Kazuo Hara Department of Medicine Division of Endocrinology and Metabolism Jichi Medical University Saitama Medical Center Saitama Japan

Diabetic chorea (DC) is a rare complication of diabetes. Here we describe two cases of DC;patient 1 was an 87-year-old woman with chronic kidney disease and was administered with sulphonylurea and dipeptidylpeptodase-4 inhibitor. She showed right side hemiballismus and head magnetic resonance imaging T1-weighted images revealed a high intensity area in the putamen and caudate nucleus. Patient 2 was a 51-year-old woman who was diagnosed with diabetic ketoacidosis. She showed right side hemiballism and multiple, small hyperintense regions in both the periventricular sides in diffusion weighted images. Based on the hemiballism, we concluded a diagnosis of DC in the diabetic patient, although the case presentation is rare or has atypical MRI findings.

关键词： Diabetes Mellitus Hyperglycemia Magnetic Resonance Imaging Hemi-ballism

Role of renal proximal tubule transport in thiazolidinedioneinduced volume expansion

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World Journal of Nephrology 2012年第5期1卷 146-150页

作者： George Seki Yoko Endo masashi Suzuki Hideomi yamada Shoko Horita Toshiro Fujita Department of Internal Medicine Faculty of Medicine University of Tokyo 7-3-1 Bunkyo-ku Hongo Tokyo 113-0033 Japan

Thiazolidinediones （TZDs）, pharmacological activa-tors of peroxisome-proliferator-activated receptors γ （PPARγ）, significantly improve insulin resistance and lower plasma glucose concentrations. However, the use of TZDs is associated with plasma volume expansion, the mechanism of which has been a matter of contro-versy. Originally, PPARγ-mediated enhanced transcrip-tion of the epithelial Na channel （ENaC） γ subunit was thought to play a central role in TZD-induced volume expansion. However, later studies suggested that the activation of ENaC alone could not explain TZD-induced volume expansion. We have recently shown that TZDs rapidly stimulate sodium-coupled bicarbonate absorp-tion from renal proximal tubule （PT） in vitro and in vivo. TZD-induced transport stimulation was dependent on PPARγ/Src/EGFR/ERK, and observed in rat, rabbit and human. However, this stimulation was not observed in mouse PTs where Src/EGFR is constitutively activated. Analysis in mouse embryonic fbroblast cells confrmed the existence of PPARγ/Src-dependent non-genomic signaling, which requires the ligand binding ability but not the transcriptional activity of PPARγ. The TZD-in-duced enhancement of association between PPARγ and Src supports an obligatory role for Src in this signal-ing. These results support the view that TZD-induced volume expansion is multifactorial. In addition to the PPARγ-dependent enhanced expression of the sodium transport system（s） in distal nephrons, the PPARγ-dependent non-genomic stimulation of renal proximal transport may be also involved in TZD-induced volume expansion.

关键词： Thiazolidinediones Peroxisome-proliferator-activated receptors γ Volume expansion Edema NBCe1 NHE3 Epithelial Na channel

Surgical treatment for a combined anterior cruciate ligament and posterior cruciate ligament avulsion fracture: A case report

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World Journal of Clinical Cases 2022年第12期10卷 3879-3885页

作者： Katsuhiro Yoshida Michiyuki Hakozaki Hideo Kobayashi masashi Kimura Shinichi Konno Department of Orthopaedic Surgery Fukushima Medical University School of MedicineFukushima 960-1295Japan Higashi-Shirakawa Orthopaedic Academy Fukushima Medical University School of MedicineFukushima 960-1295Japan Department of Orthopaedic Surgery Sukagawa HospitalFukushima 962-0022Japan Gunma Sports Medicine Research Center Zenshukai HospitalGunma 379-2115Japan

BACKGROUND Independent avulsion fractures with anterior cruciate ligament(ACL)or posterior cruciate ligament(PCL)attachment are relatively common among tibial intercondylar eminence fractures,and their postoperative outcomes are generally ***,huge avulsion fractures of the intercondylar eminence containing the attachment site of both the ACL and the PCL are extremely rare,and the reported clinical outcomes are *** SUMMARY We describe a 30-year-old Japanese male's huge avulsion fracture of the intercondylar eminence of a tibia containing the attachment site of both the ACL and PCL,together with a complete tear of the medial collateral ligament and a partial tear of both the medial and lateral menisci caused by a fall from a high *** of these injuries were treated surgically,with anatomical reduction and stable *** limb function at 1 year post-surgery was excellent(Lysholm score:100 points).CONCLUSION Although this patient's complete surgical repair was complex,it should be performed in similar cases for an excellent final clinical outcome.

关键词： Avulsion fracture Intercondylar eminence Tibia Anterior cruciate ligament Posterior cruciate ligament Meniscal tear

A model to estimate available timber and forest biomass and reforestation expenses in a mountainous region in Japan

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Journal of Forestry Research 2013年第2期24卷 345-356页

作者： Kazuhiro Aruga Ayami Murakami Chikara Nakahata Reiko Yamaguchi masashi Saito Kanae Kanetsuki Department of Forest Science Faculty of Agriculture Utsunomiya University Frontier Agriscience and Technology Center Faculty of Agriculture Shinshu University Nasunogahara Land Improvement Districts

We developed a model to estimate supply potentials and available amounts of timber and forest biomass resources from profitable sub-compartments of thinning and final felling operations. Economic balances were estimated while considering not only harvesting expenses but also reforestation expenses after final felling, which should be considered for sustainable forest management. Harvesting expenses were estimated based on two types of timber harvesting systems and three types of forest biomass harvesting systems in each sub-compartment. Then, the model was applied to Nasushiobara city of Tochigi prefecture, Japan. Reforestation expenses had large negative impacts on the financial balances of final felling operations. Few sub-compartments were profitable after considering reforestation expenses. Most profitable sub-compartments were those with mechanized operation systems and landing sales. These accounted for 17.19% of all sub-compartments, while only 5.75% of the sub-compartments were profitable based on their current operation systems and landing sales. Although the overall supply potentials of timber and forest biomass resources were 380,000 m3 and 210,000 Mg, respectively, and 15 times the planned harvest of coniferous tree volume of 25,000 m3year-1 and 50 times the annual demand for the woody gasification power generation of 4,000 Mg year-1 in Nasushiobara, available amounts of timber and forest biomass resources were only49,429 m3 and 33,333 Mg, which were 13.0% and 15.7% of supply potentials for landing sales with mechanized operation systems.

关键词： forest biomass resources supply potentials available amounts economic balance GIS

Genome-Wide Association Study Reveals Host Genetic Factors for Liver Diseases

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Journal of Clinical and Translational Hepatology 2013年第1期1卷 45-50页

作者： Nao Nishida Katsushi Tokunaga masashi Mizokami The Research Center for Hepatitis&Immunology National Center for Global Health and Medicine Ichikawa Chiba Japan Department of Human Genetics The University of Tokyo Bunkyo-ku Tokyo Japan Department of Human Genetics The University of Tokyo Bunkyo-ku Tokyo Japan The Research Center for Hepatitis&Immunology National Center for Global Health and Medicine Ichikawa Chiba Japan

A number of disease-associated genetic markers for common liver diseases have been identified using genome-wide association studies (GWASs). The GWAS strategy is based on genome-wide single-nucleotide polymorphism typing technologies, which are now commercially available, accom-panied by statistical methods to identify host genetic factors that are associated with target diseases or complex genetic traits. One of the most striking features of the GWAS strategy is the ability to identify unexpected disease-associated genetic markers across the entire human genome. Here, we describe the technological aspects of the GWAS strategy with examples from actual GWAS reports related to hepatitis research, including drug response for patients with chronic hepatitis C, susceptibility to primary biliary cirrhosis, and hepatitis-B-related hepatocellular carcinoma.

关键词： GWAS Hepatitis B infection Hepatitis C infection Primary biliary cirrhosis HLA-DP Hepatocellular carcinoma Host genetic factors

Morphology and gene expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 in centrifugally compressed cell collagen‐combined constructs (C^(6))

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Biosurface and Biotribology 2023年第3期9卷 78-83页

作者： Xu Ye masashi Yamazaki Wataru Ando Norimasa Nakamura Hiromichi Fujie Faculty of System Design Tokyo Metropolitan UniversityTokyoJapan Research Center for Medicine‐Engineering Collaboration TokyoJapan Department of Orthopaedic Surgery Kansai Rosai HospitalAmagasakiJapan Department of Orthopaedic Surgery Osaka University Graduate School of MedicineSuitaJapan Institute for Medical Science in Sports Osaka Health Science UniversityOsakaJapan Center for Advanced Medical Engineering and Informatics Osaka UniversitySuitaJapan

The authors previously developed a scaffold‐free tissue‐engineered construct(TEC)from mesenchymal stem cells(MSCs).Although the TEC exhibited even cell distribution and was successfully applied for cartilage repair in animal models,it is unsuitable for relatively large‐scale cartilage defects due to its small *** solve the problem,the authors recently developed a novel biomaterial,a centrifugally compressed cell‐collagen combined construct(C^(6))from a mixture of MSCs and atelocollagen,both of which are subjected to *** results of the previous study indicated that C^(6) exhibited high cell viability(70%)and sufficient cell distribution similar to that of the *** the present study,the morphology and gene expression of C^(6) were *** ex-amination indicated that C6 is six times thicker(approximately 1 mm)than the TEC after a 7‐day *** C^(6) remained unchanged in scale with increased cell density after a 21‐day *** electron microscopic observation indicated that C^(6) exhibited interconnected and porous microstructures,while the TEC had close‐knit *** transcriptase‐polymerase chain reaction analysis indicated that the expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 was significantly higher in C^(6) than that in TEC.

关键词： biomaterials cartilage microstructures

Investigation and prediction of enteral nutrition problems after percutaneous endoscopic gastrostomy

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World Journal of Gastroenterology 2009年第11期15卷 1367-1372页

作者： Shiro Yokohama Masaru Aoshima Yukiomi Nakade Junya Shindo Junichi Maruyama masashi Yoneda Department of Gastroenterology Asahikawa Rehabilitation HospitalAsahikawa078-8801Japan Division of Gastro-enterology Department of Internal MedicineAichi Medical University School of MedicineAichi 480-1195Japan Department of Rehabilitation Asahikawa Rehabilitation HospitalAsahikawa 078-8801Japan Department of Internal Medicine Asahikawa Rehabilitation HospitalAsahikawa 078-8801Japan

AIM： To investigate and predict enteral nutrition problems after percutaneous endoscopic gastrostomy （PEG）. METHODS： We retrospectively analyzed data for 252 out of 285 patients who underwent PEG at our hospital from 1999 to 2008 after PEG were defined as： Enteral nutrition problems （1） patients who required ≥ 1 mo after surgery to switch to complete enteral nutrition, or who required additional parenteral alimentation continuously; or （2） patients who abandoned switching to enteral nutrition using the gastrostoma and employed other nutritional methods. We attempted to identify the predictors of problem cases by using a logistic regression analysis that examined the patients＇ backgrounds and the specific causes that led to their problems. RESULTS： Mean age of the patients was 75 years, and in general, their body weight was low and their overall condition was markedly poor. Blood testing revealed that patients tended to be anemic and malnourished. A total of 44 patients （17.5%） were diagnosed as having enteral nutrition problems after PEG. Major causes of the problems included pneumonia, acute enterocolitis （often Clostridium difficile-related）, paralytic ileus and biliary tract infection. A multivariate analysis identified the following independent predictors for problem cases：（1） enteral nutrition before gastrectomy （a risk reduction factor）; （2） presence of esophageal hiatal hernia; （3） past history of paralytic ileus; and （4） presence of chronic renal dysfunction. CONCLUSION： Enteral nutrition problems after PEG occurred at a comparatively high rate. Patient background analysis elucidated four predictive factors for the problem cases.

关键词： Percutaneous endoscopic gastrostomy Enteral nutrition Complication, Risk factor Predictor