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Hyperglycemia is a significant prognostic factor of hepatocellular carcinoma after curative therapy

World Journal of Gastroenterology 2013年第2期19卷 249-257页

作者： Takanori Hosokawa Masayuki Kurosaki Kaoru Tsuchiya Shuya Matsuda masaru muraoka Yuichiro Suzuki Nobuharu Tamaki Yutaka Yasui Toru Nakata Takashi Nishimura Shoko Suzuki Ken Ueda Hiroyuki Nakanishi Jun Itakura Yuka Takahashi Namiki Izumi Division of Gastroenterology and Hepatology Musashino Red Cross HospitalTokyo 180-8610Japan

AIM:To evaluate whether metabolic factors are related to distant recurrence of hepatocellular carcinoma(HCC) and survival after curative ***:This retrospective study included 344 patients whose HCC was treated curatively by radiofrequency ablation(RFA) *** mean age was 67.6 years and the mean observation period was 4.04 *** etiological background of liver disease was hepatitis B virus infection in 30,hepatitis C virus infection in 278,excessive alcohol drinking in 9,and other in 27 *** Child-Pugh classification grade was A(n = 307) or B(n = 37).The number of HCC nodules was one in 260,two in 61,and three in 23 *** surveillance of HCC recurrence after curative therapy with RFA,patients were radiologically evaluated every 3 *** associated with distant recurrence of HCC or survival were ***:Inadequate maintenance of blood glucose in diabetic patients was associated with higher incidence of distant *** 1-,2-,and 3-year recurrence rates were significantly higher in diabetic patients with inadequate maintenance of blood glucose compared with the others:50.6% vs 26.8%,83.5% vs 54.4%,and 93.8% vs 73.0%,respectively(P = 0.0001).Inadequate maintenance of blood glucose was an independent predictor of distant recurrence [adjusted relative risk 1.97(95%CI,1.33-2.91),(P = 0.0007)] after adjustment for other risk factors,such as number of HCC nodules [2.03(95%CI,1.51-2.73),P < 0.0001] and initial level of serum alpha fetoprotein(AFP) [1.43(95%CI,1.04-1.97),P = 0.028].Obesity was not an independent predictor of *** incidence of distant recurrence did not differ between diabetic patients with adequate maintenance of blood glucose and non-diabetic *** 232 patients who had HCC recurrence,138 had a second *** 1-,2-,and 3-year rates of second recurrence were significantly higher in diabetic patients with inadequate maintenance of blood glucose than in the others:9.0% vs 5.9%,53.1

关键词： Hyperglycemia Hepatocellular carcinoma Recurrence Radio frequency ablation Survival

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A comparison of electromigration failure of metal lines with fracture mechanics

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Acta Mechanica Sinica 2012年第3期28卷 774-781页

作者： Hiroyuki Abé Mikio muraoka Kazuhiko Sasagawa Masumi Saka Tohoku University Sendai 980-8579Japan Department of Mechanical Engineering Akita UniversityTegatagakuen-machi 1-1Akita 010-8502Japan Department of Intelligent Machines and System Engineering Hirosaki UniversityBunkyo-cho 3Hirosaki 036-8561Japan Department of Nanomechanics Tohoku UniversityAoba 6-6-01AramakiAoba-kuSendai 980-8579Japan

Atoms constructing an interconnecting metal line in a semiconductor device are transported by electron flow in high density. This phenomenon is called electromigration, which may cause the line failure. In order to characterize the electromigration failure, a comparison study is carded out with some typical phenomena treated by fracture mechanics for thin and large structures. An example of thin structures, which have been treated by fracture mechanics, is silica opti- cal fibers for communication systems. The damage growth in a metal line by electromigration is characterized in compar- ison with the crack growth in a silica optical fiber subjected to static fatigue. Also a brief comparison is made between the electromigration failure and some fracture phenomena in large structures.

关键词： Electromigration failure. Interconnecting line Comparison Fracture mechanics

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Selective CO_(2) reduction into formate using Ln-Ta oxynitrides combined with a binuclear Ru(Ⅱ)complex under visible light

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Journal of Energy Chemistry 2021年第4期30卷 176-182页

作者： Kanemichi muraoka Miharu Eguchi Osamu Ishitani Francois Chevire Kazuhiko Maeda Department of Chemistry School of ScienceTokyo Institute of TechnologyMeguro-ku152-8550 TokyoJapan Japan Society for the Promotion of Science Chiyoda-ku102-0083 TokyoJapan Research Center for Functional Materials National Institute for Materials ScienceTsukuba 305-0044IbarakiJapan Univ Rennes CNRSISCR-UMR 6226Rennes F-35000France

Hybrid materials constructed from a visible-light-absorbing semiconductor and a functional metal complex have attracted attention as efficient photocatalysts for CO_(2) reduction with high selectivity to a desired *** this work,defect fluorite-type Ln-Ta oxynitrides LnTaO_(x)N_(y)(Ln=Nd,Sm,Gd,Tb,Dy and Ho)were examined as the semiconductor component in a hybrid photocatalyst system combined with known Ag nanoparticle promoter and binuclear ruthenium(Ⅱ)complex(RuRu’).Among the LnTaO_(x)N_(y) examined,TbTaO_(x)N_(y) gave the highest performance for CO_(2) reduction under visible light(k>400 nm),with a Ru Ru0-based turnover number of 18 and high selectivity to formate(>99%).Physicochemical analyses indicated that high crystallinity and more negative conduction band potential of Ln Ta O_(x)N_(y)with the absence of Ln-4 f states in the band gap structure contributed to higher activity of the hybrid photocatalyst.

关键词： Artificial photosynthesis Heterogeneous photocatalysis Mixed anion compounds Solar fuels

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Performance tests of newly developed adsorption/plasma combined system for decomposition of volatile organic compounds under continuous flow condition

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Journal of Environmental Sciences 2011年第1期23卷 139-144页

作者： Koji Inoue Hiroshi Okano Yukihiko Yamagata Katsunori muraoka Yasutake Teraoka Seibu Giken Co.Ltd. Fukuoka 811-3134Japan Department of Molecular and Material Sciences Interdisciplinary Graduate School of Engineering SciencesKyushu UniversityFukuoka 816-8580Japan Department of Engineering Sciences for Electronics and Materials Faculty of Engineering SciencesKyushu UniversityFukuoka 816-8580Japan Department of Natural Science and Mathematics College of EngineeringChubu UniversityAichi 487-8501Japan Department of Energy and Material Sciences Faculty of Engineering SciencesKyushu UniversityFukuoka 816-8580Japan

The adsorption/plasma decomposition with the combination of adsorption honeycomb-sheets and a plasma element is a new technology for small-sized apparatuses to decompose volatile organic compounds （VOCs） at concentrations lower than about 100 ppm. The feasibility of the prototype adsorption/plasma decomposition apparatus was evaluated with the simulated exhausts containing one VOC component and with real exhausts from a painting booth and an adhesion factory. The apparatus decomposed VOCs effectively at the painting booth exhaust but not always satisfactorily at the adhesion factory exhaust. The performance test results with real exhausts were discussed with respect to the concentration and discharge pattern of the exhausts and the basic properties of the system such as cooperation of adsorption and plasma reaction and the concentration dependence of the performance.

关键词： volatile organic compounds adsorption hydrophobic zeolite honeycomb plasma

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Control of Collection Efficiency for Axial Flow Cyclone Dust Collectors with Fixed Guide Vanes and with Funnel Shaped Exit Pipes

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Journal of Thermal Science 2006年第3期15卷 240-250页

作者： Akira Ogawa masaru Arakawa T-110-0011 Minowa 2-14-7Taitou-KuTokyoJapan SHINWA RULES Co. Ltd.Sanjo-ShiNiigataJapan

The experimental result of the collection efficiency of the axial flow cyclone with the fixed guide vanes is lower than that with the tangential inlet pipe to the cyclone body due to the weak angular momentum transfer given by flowing through the guide vanes. However, one of the interesting points is the control of the collection efficiency depended on the funnel shaped exit pipes. The collection efficiencies for these funnel shaped exit pipes are depended on the Froude number. Then, in this paper, the experimental results of the pressure drop and also the collection efficiency using the fly-ash particles and also the comparison of the calculated results of the collection efficiency with the experimental results are described i~ detail.

关键词： Axial flow cyclone funnel shaped exit pipe fixed guide vanes pressure drop collection efficiency,Froude number cut-Size

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Mechanisms of fertilization elucidated by gene-manipulated animals

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Asian Journal of Andrology 2015年第4期17卷 646-652页

作者： masaru Okabe Center for Genetic Analysis for Biological ResponsesResearch Institute for Microbial Diseases OsakaUniversity Yamadaoka 3-1 Suita Osaka 565-0871Japan.

Capacitation and the acrosome reaction are key phenomena in mammalian fertilization. These phenomena were found more than 60 years ago. However, fundamental questions regarding the nature of capacitation and the timing of the acrosome reaction remain unsolved. Factors were postulated overtime, but as their roles were not verified by gene-disruption experiments, widely accepted notions concemingthe mechanism of fertilization are facing modifications. Today, although in vitro fertilization systems remain our central research tool, the importance of in vivo observations must be revisited. Here, primarily focusing on our own research, I summarize how in vivo observations using gene-manipulated animals have elucidated new concepts in the mechanisms of fertilization.

关键词： Mechanisms fertilization gene-manipulated

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Photocatalytic dry reforming of methane by rhodium supported monoclinic TiO_(2)-B nanobelts

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Journal of Energy Chemistry 2022年第8期31卷 562-571,I0015页

作者： masaru Kushida Akira Yamaguchi Masahiro Miyauchi School of Materials and Chemical Technology Tokyo Institute of Technology2-12-1 OokayamaMeguro-kuTokyo 152-8552Japan

The conversion of methane and carbon dioxide into syngas(dry reforming of methane;DRM)has attracted attention owing to the potential to reuse greenhouse *** dioxide(TiO_(2))-based photocatalysts,which have been widely commercialized owing to their high efficiency,non-toxicity,and low cost,are strongly desired in ***,we report a monoclinic-phase TiO_(2)-B nanobelts-supported rhodium(Rh/TiO_(2)-B nanobelts)catalyst that efficiently promotes DRM under ultraviolet light irradiation at low *** holes in the TiO_(2)-B nanobelts were used to oxidize methane,while the electrons were trapped in rhodium to reduce carbon ***/TiO_(2)-B nanobelts exhibited considerably higher durability and activity than Rh-loaded conventional TiO_(2)(anatase and rutile),owing to the lattice and/or surface oxygen reactivity in TiO_(2)-B nanobelts,which was suggested by X-ray photoelectron spectroscopy measurements and photocatalytic performance tests under an atmosphere of methane *** study paves the path for the effective utilization of methane by constructing active TiO_(2)-based nanometal photocatalysts.

关键词： Photocatalysis Dry reforming of methane Greenhouse gas conversion Gas-phase reaction Titanium dioxide TiO_(2)-B

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Effects of zincate treatment on adhesion of electroless Ni-P coating onto various aluminum alloys

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中国有色金属学会会刊：英文版 2009年第4期19卷 814-818页

作者： Makoto HINO Koji MURAKAMI Yutaka MITO OKA Ken muraoka Teruto KANADANI Industrial Technology Research Institute of Okayama Prefecture Okayama University of Science

The effects of alloying elements on zincate treatment and adhesion of electroless Ni-P coating onto various aluminum alloy substrates were *** morphology of zinc deposits in the 1st zincate treatment and its adhesion were changed depending on the alloying *** zinc deposits in the 2nd zincate treatment became thinly uniform,and the adhesion between aluminum alloy substrate and Ni-P coating was improved irrespective of the alloying *** analysis revealed the existence of zinc on the surface of each aluminum alloy substrate after the pickling in 5% nitric *** zinc on the surface should be an important factor influencing the morphology of zinc deposit at the 2nd zincate treatment and its adhesion.

关键词：化学镀镍锌酸盐铝合金治疗合金涂层粘连合金元素表面形貌

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Velocity Measurement of Induced Flow by a Laser Focusing Shock Wave

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Journal of Thermal Science 2006年第1期15卷 48-53,26页

作者： Hiroyuki HIRAHARA masaru FUJINAMI Masaaki KAWAHASHI Department of Mechanical Engineering Saitama University 255 Shimo-Okubo Sakura Saitama 338-8570Japan. Graduate School of Science and Engineering Saitama University Japan

The objective of this study is to apply the shock wave for control in a micro channel. The shock wave was generated by a laser focusing of pulsed laser beam in the channel. Using a pulse laser to generate a shock wave, a non-stationary flow was induced in the small space between the parallel plates. The spherical and cylindrical shock propagations were observed with schlieren method. The shock Mach number decreases with time and approaches to unity. As reported in the previous investigations, the shock speed was attenuated in a short distance and time. In the present experiment, It was not found a remarkable difference in the shock speed between the spherical and cylindrical shock experiments. Subsequently, the flow induced by the cylindrical shock wave was studied using PIV technique. A smoke tracer was used in the experiment and its velocity was measured within 100 μs. A numerical simulation was carried out to investigate the momentum relaxation between the gas and smoke particle. A suitable shock initiation model was introduced in the simulation. The experimental results show that a wide acceleration and deceleration zone exist behind the shock wave. Also, the relaxation distance in the experimental data is much longer than that in numerical simulation.

关键词： micro-blast wave laser focusing flow visualization PIV.

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The mechanism of sperm-egg interaction and the involvement of IZUMO1 in fusion

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Asian Journal of Andrology 2011年第1期13卷 81-87页

作者： Naokazu Inoue Masahito Ikawa masaru Okabe Research Institute for Microbial Diseases Osaka University Yamadaoka 3-1 Suita Osaka 565-0871 Japan

An average human ejaculate contains over 100 million sperm, but only a few succeed in accomplishing the journey to an egg by migration through the female reproductive tract. Among these few sperm, only one participates in fertilization. There might be an ingenious molecular mechanism to ensure that the very best sperm fertilize an egg. However, recent gene disruption experiments in mice have revealed that many factors previously described as important for fertilization are largely dispensable. One could argue that the fertilization mechanism is made robust against gene disruptions. However, this is not likely, as there are already six different gene-disrupted mouse lines （Calmegin, Adam Ia, Adam2, Adam3, Ace and Pgapl）, all of which result in male sterility. The sperm from these animals are known to have defective zona-binding ability and at the same time lose oviduct-migrating ability. Concerning spermzona binding, the widely accepted involvement of sugar moiety on zona pellucida 3 （ZP3） is indicated to be dispensable by gene disruption experiments. Thus, the landscape of the mechanism of fertilization is revolving considerably. In the sperm-egg fusion process, CD9 on egg and IZUMO1 on sperm have emerged as essential factors. This review focuses on the mechanism of fertilization elucidated by gene-manipulated animals.

关键词： egg fusion gene-manipulation interaction IZUMO1 sperm zona pellucida

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