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Contribution of adult-born neurons to memory consolidation during rapid eye movement sleep

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Neural Regeneration Research 2022年第2期17卷 307-308页

作者： Akinobu Ohba masanori Sakaguchi International Institute for Integrative Sleep Medicine(WPI-IIIS) University of TsukubaTsukubaIbarakiJapan

Introduction: Memory consolidation stabilizes newly acquired memories by integrating them into pre-existing memory networks, which is thought to occurvia changes in synaptic strength. Sleep may influence memory consol... 详细信息

关键词： strength. sleep integrating

A Switching Controller System for a Wheeled Mobile Robot

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Journal of Bionic Engineering 2007年第4期4卷 281-289页

作者： masanori Sato Atushi Kanda Kazuo Ishii Department of Brain Science and Engineering Kyushu Institute of Technology Kitakyushu 808-0196 Japan

A wheeled mobile mechanism with a passive and/or active linkage mechanism for rough terrain environment is developed and evaluated. The wheeled mobile mechanism which has high mobility in rough terrain needs sophisticated system to adapt various environments. We focus on the development of a switching controller system for wheeled mobile robots in rough terrain. This system consists of two sub-systems： an environment recognition system using link angles and an adaptive control system. In the environment recognition system, we introduce a Self-Organizing Map （SOM） for clustering link angles. In the adaptive controllers, we introduce neural networks to calculate the inverse model of the wheeled mobile robot. The environment recognition system can recognize the environment in which the robot travels, and the adjustable controllers are tuned by experimental results for each environment. The dual sub-system switching controller system is experimentally evaluated. The system recognizes its environment and adapts by switching the adjustable controllers. This system demonstrates superior performance to a well-tuned single PID controller.

关键词： mobile robot rough terrain neural network Self-Organizing Map

Fatigue sensation following peripheral viral infection is triggered by neuroinflammation: who will answer these questions?

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Neural Regeneration Research 2015年第2期10卷 203-204页

作者： masanori Yamato Yosky Kataoka Cellular Function Imaging Team RIKEN Center for Life Science Technologies

Fatigue is best defined as difficulty in initiating or sustaining voluntary activities, and is thought to be accompanied by deterioration of performance. Fatigue can be caused by many factors such as physical and mental stress, disturbance in the circadian rhythm, and various diseases. For example, following the flu or other types of infections, everyone has experienced a sense of fatigue that can last for days or weeks. The fatigue sensation is thought to be one of the signals for the body to suppress physical activity in order to regain health. The mechanism of induction of the fatigue sensation following viral infection has not been well understood. Although fatigue was once thought to be caused by fever, our recent study with an animal model of viral infection demonstrated that the fatigue sensation is caused not by fever, but rather,

关键词： who will answer these questions will

Flow Behavior in Z-Path Fluidized-Moving Bed with Inclined Perforated Plate

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Journal of Iron and Steel Research International 2002年第1期9卷 19-24页

作者： GUO Zhan-cheng TOKUDA masanori Institute of Process Engineering CAS Center for Northeast Asia Studies Tohoku University

Much researches on the operation and structure of tundish were carried out at Xiangtan Iron and Steel Co Ltd to increase the yield of grade 20 carbon steel on the continuous casting production line. Through analyzing formation mechanism of pinholes and non metallic inclusions in billets and describing pattern of the flow of molten steel in tundish by a mathematic model, it was shown that the structure and operation of tundishes play an important part in product quality. So some measures were taken as follows: (1) Optimizing the tundish construction to decrease the impact of liquid steel and lengthening the residence time of liquid steel for homogenization of liquid steel; (2) Improving the influent and effluent operation of liquid steel to avoid the contact of liquid steel with air in order to decrease reoxidation; (3) Reducing over heat during continuous casting. After above measures being taken, the yield of grade 20 carbon steel and the service life of equipment were improved remarkably.

关键词： carbon steel continuous casting quality tundish

Tuning of RF amplitude and phase for the drift tube linac in J-PARC

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Chinese Physics C 2009年第7期33卷 577-582页

作者：沈国保 masanori Ikegami Japan Atomic Energy Agency(JAEA) 2-4 Shirakata-Shirane High Energy Accelerator Research Organization(KEK)

The J-PARC linac has three DTL tanks to accelerate the negative hydrogen ions from 3 MeV to 50 MeV. The RF phase and amplitude are adjusted for each cavity with a phase scan method within the accuracy of 1° in phase and 1% in amplitude. The experimental results show a remarkable agreement with the numerical model within a suffcient margin in the tuning of the last two DTL tanks. However,a notable discrepancy between the experiment and the numerical model is seen in the tuning of the first DTL tank. After studying with a three-dimensional multi-particle simulation,the generation of the low energy component and the pronounced filamentation are identified as the main causes of the discrepancy. The optimization of the tuning scheme is also discussed to attain the tuning goal accuracy for the first DTL tank.

关键词： high-intensity beam drift tube linac signature matching J-PARC

A reactor system combining reductive dechlorination with co-metabolic oxidation for complete degradation of tetrachloro-entylene

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Journal of Environmental Sciences 2002年第4期14卷 445-450页

作者： TAE HO LEE MICHIHIKO IKE masanori FUJITA Department of Environmental Engineering Osaka University 2-1 YamadaokaDepartment of Environmental Engineering Osaka University 2-1 YamadaokaDepartment of Environmental Engineering Osaka University 2-1 Yamadaoka Suita Osaka 565-0871 Japan.Suit

A laboratory sequential anaerobic aerobic bioreactor system, which consisted of an anaerobic fixed film reactor and two aerobic chemostats, was set up to degrade tetrachloroethylene (PCE) without accumulating highly toxic degradation intermediates. A soil enrichment culture, which could reductively dechlorinate 900 μM (ca. 150 mg/L) of PCE stoichiometrically into cis 1,2 dichloroethylene ( cis DCE), was attached to ceramic media in the anaerobic fixed film reactor. A phenol degrading strain, Alcaligenes sp. R5, which can efficiently degrade cis DCE by co metabolic oxidation, was used as inoculum for the aerobic chemostats consisted of a transformation reactor and a growth reactor. The anaerobic fixed film bioreactor showed more than 99 % of PCE transformation into cis DCE in the range of influent PCE concentration from 5 μM to 35 μM at hydraulic retention time of 48h. On the other hand, efficient degradation of the resultant cis DCE by strain R5 in the following aerobic system could not be achieved due to oxygen limitation. However, 54% of the maximum cis DCE degradation was obtained when 10 μmol of hydrogen peroxide (H 2O 2) was supplemented to the transformation reactor as an additional oxygen source. Further studies are needed to achieve more efficient co metabolic degradation of cis DCE in the aerobic reactor.

关键词： anaerobic aerobic bioreactor co oxidation reductive dechlorination tetrachloroethylene

Solvent Extraction of Niobium from Alkali Solution by Methyltrioctylammonium Chloride

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Journal of Central South University 2000年第4期12卷 175-177页

作者： ZHOU Kang-gen TOKUDA masanori Metallurgical Separation Science and Engineering Lab. Central South UniversityChangsha 410083China Tohoku University Sendai 980-77Japan

For the purpose of developing an alkali leaching solvent extraction directly from alkali solution process, the extraction of niobium from alkali solution by long chain alkyl quaternary ammonium salt (methyltrioctylammonium chloride R 4NCl) in toluene was investigated. The experiments were carried out under conditions of 25 ℃, Nb(Ⅴ) concentration 0.01 mol/L, pH 10.7 13.8, R 4NCl concentration 0.02 0.14 mol/L. It has been found that the distribution ratio of niobium increases with increasing R 4NCl concentration and with decreasing KCl concentration, but it shows maximum value at pH value of about 12 and decreases below or above this pH value. Distribution ratio of niobium goes up to over 1 000 in appropriate conditions, and so it has been proved that R 4NCl is an effective extractant for extraction of niobium from alkali solution.

关键词： niobium solvent extraction distribution ratio methyltrioctylammonium chloride

Endoscopic findings can predict the efficacy of leukocytapheresis for steroid-naive patients with moderately active ulcerative colitis

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World Journal of Gastroenterology 2008年第34期14卷 5316-5321页

作者： Yasushi Umehara Masatoshi Kudo masanori Kawasaki Division of Gastroenterology and Hepatology Department of Internal Medicine Kinki University School of Medicine

AIM:To investigate the therapeutic usefulness of leukocytapheresis (LCAP; Cellsoba) in steroid-naive patients with moderately active ulcerative colitis (UC). METHODS: Eighteen steroid-naive patients with moderately active UC received one LCAP session every week for fi ve consecutive weeks. RESULTS: The remission rate 8 weeks after the last LCAP session was 61.1% (11/18). All three patients with deep ulcers showed worsening after LCAP. For the remaining 15 patients, who had erosions or geographic ulcers, the average clinical activity index (CAI) score dropped significantly from 9.4 to 3.8 eight weeks after the last LCAP session (t = 4.89, P = 0.001). The average C-reactive protein (CRP) levels before and after LCAP were 1.2 mg/dL and 1.0 mg/dL, respectively. Of the patients with erosions, geographic ulcers, and deep ulcers, 100% (9/9), 33.3% (2/6), and 0% (0/3) were in remission 8 weeks after the last LCAP session, respectively (χ2 = 7.65, P < 0.005). Forty- eight weeks after the last LCAP session, the remission rates for patients with erosions and geographic ulcers were 44.4% (4/9) and 16.7% (1/6), respectively. Only one patient suffered a mild adverse event after LCAP (nausea). CONCLUSION: LCAP is a useful and safe therapyfor steroid-naive UC patients with moderate disease activity. Moreover, the effi cacy of the treatment can be predicted on the basis of endoscopic fi ndings.

关键词： Ulcerative colitis Steroid-naive Leukocytapheresis Efficacy Endoscopic findings

Linear Stability Analysis on the Influences of the Spatial Variations in Thermal Conductivity and Expansivity on the Flow Patterns of Thermal Convection with Strongly Temperature-Dependent Viscosity

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Journal of Earth Science 2014年第1期25卷 126-139页

作者： Arata Miyauchi masanori Kameyama Hiroki Ichikawa Geodynamics Research Center Ehime University

A series of linear stability analysis is carried out on the onset of thermal convection in the presence of spatial variations of viscosity, thermal conductivity and expansivity. We consider the temporal evolution of an infinitesimal perturbation superimposed to a static （motionless） and con- ductive state in a basally-heated planar layer. From the changes in flow patterns with increasing the amplitudes of temperature dependence of viscosity, we identified the transition into the ＂stagnant-lid＂（ST） regime, where the convection occurs only beneath a thick and stagnant-lid of cold fluid at the top surface. Detailed analysis showed a significant increase of the aspect ratio of convection cells in ST regime induced by the spatial variations in thermal conductivity and/or expansivity： the horizon- tal length scale of ST convection can be enlarged by up to 50% with 10 times increase of thermal conductivity with depth. We further developed an analytical model of ST convection which success- fully reproduced the mechanism of increasing horizontal length scale of ST regime convection cells for given spatial variations in physical properties. Our findings may highlight the essential roles of the spatial variation of thermal conductivity on the convection patterns in the mantle.

关键词： mantle convection stagnant-lid temperature-dependent viscosity pressure- dependent thermal conductivity pressure-dependent thermal expansivity linear stability analysis.