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Right hepatectomy for giant cavernous hemangioma with diffuse hemangiomatosis around Glisson's capsule

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World Journal of Gastroenterology 2014年第25期20卷 8312-8316页

作者： Yu Ohkura Masaji Hashimoto Seigi Lee Kazunari Sasaki masamichi matsuda Goro Watanabe Department of Digestive Surgery Hepato Pancreato Billiary Surgery UnitToranomon HospitalTokyo 105-8470Japan

Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast enhancement at the periphery of the mass consistent with a cavernous hemangioma. She underwent right hepatectomy. Histologically, it was diagnosed as a cavernous hemangioma. And also, hemangiomatous lesions were scattered around the Glisson’s capsule on the back ground liver. These hemangiomatous lesions were not recognized preoperatively. Even if we couldn’t diagnose hemangiomatosis around the main giant hemangioma preoperatively, we need to take enough surgical margins because the giant hemangioma has the potential to have small hemangiomatous lesions around the tumor. We reported right hepatectomy for giant cavernous hemangioma with diffuse hepatic hemangiomatosis without an extrahepatic lesion in an adult.

关键词： Giant cavernous hemangioma Hemangiomatosis Right hepatectomy Around Glisson’ s capsule Surgery

Liver resection for hepatocellular carcinoma using a microwave tissue coagulator: Experience of 1118 cases

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World Journal of Gastroenterology 2015年第36期21卷 10400-10408页

作者： Kazunari Sasaki masamichi matsuda Masaji Hashimoto Goro Watanabe Department of Digestive Surgery Hepato-pancreatobiliary Surgery UnitToranomon Hospital

A I M : To present our extensive experience of hepatectomy for hepatocellular carcinoma using a microwave tissue coagulator to demonstrate the effectiveness of this device. METHODS: A total of 1118 cases(1990-2013) were reviewed,with an emphasis on intraoperative blood loss,postoperative bile leakage and fluid/abscess formation,and adaptability to anatomical resection and hepatectomy with hilar ***: The median intraoperative blood loss was 250 m L; postoperative bile leakage and fluid/abscess formation were seen in 3.0% and 3.3% of cases,respectively. Anatomical resection was performed in 275 cases,including 103 cases of hilar dissection that required application of microwave coagulation near the hepatic hilum. There was no clinically relevant biliary tract stricture or any vascular problems due to heat injury. Regarding the influence of cirrhosis on intraoperative blood loss,no significant difference was seen between cirrhotic and non-cirrhotic patients(P = 0.38),although cirrhotic patients tended to have smaller tumors and underwent less invasive operations. CONCLUSION: This study demonstrated outcomes of an extensive experience of hepatectomy using heat coagulative necrosis by microwave tissue coagulator.

关键词： Hepatectomy Hepatocellular carcinoma Microwave Mic

Retroperitoneal cavernous hemangioma resected by a pylorus preserving pancreaticoduodenectomy

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World Journal of Gastroenterology 2013年第28期19卷 4624-4629页

作者： Marie Hanaoka Masaji Hashimoto Kazunari Sasaki masamichi matsuda Takeshi Fujii Kenichi Ohashi Goro Watanabe Department of Digestive Surgery Toranomon Hospital Tokyo 105-8470 Japan Department of Pathology Toranomon Hospital Tokyo 105-8470 Japan Department of Pathology Yokohama City University Graduate School of Medicine Kanagawa 236-0004 Japan

A retroperitoneal hemangioma is a rare disease. We report on the diagnosis and treatment of a retroperitoneal hemangioma which had uncommonly invaded into both the pancreas and duodenum, thus requiring a pylorus preserving pancreaticoduodenectomy (PpPD). A 36-year-old man presented to our hospital with abdominal pain. An enhanced computed tomography scan without contrast enhancement revealed a 12 cm × 9 cm mass between the pancreas head and right kidney. Given the high rate of malignancy associated with retroperitoneal tumors, surgical resection was performed. Intraoperatively, the tumor was inseparable from both the duodenum and pancreas and PpPD was performed due to the invasive behavior. Although malignancy was suspected, pathological diagnosis identified the tumor as a retroperitoneal cavernous hemangioma for which surgical resection was the proper diagnostic and therapeutic procedure. Reteoperitoneal cavernous hemangioma is unique in that it is typically separated from the surrounding organs. However, clinicians need to be aware of the possibility of a case, such as this, which has invaded into the surrounding organs despite its benign etiology. From this case, we recommend that combined resection of inseparable organs should be performed if the mass has invaded into other tissues due to the hazardous nature of local recurrence. In summary, this report is the first to describe a case of retroperitoneal hemangioma that had uniquely invaded into surrounding organs and was treated with PpPD.

关键词： Retroperitoneal tumor Retroperitoneal cavernous hemangioma Cavernous hemangioma Pancreaticoduodenectomy Pylorus preserving pancreaticoduodenectomy

Experimental Research of External Desulfurization in Situ Mechanical Stirring

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Journal of Iron and Steel Research International 2011年第S2期18卷 119-124页

作者： masamichi Sano Nagoya University

This paper presents a new idea about desulfurization with in-situ mechanical stirring method on the basis of desulfurization by single blow grain magnesium and KR method, that is, the inner gases carry the magnesium vapor formed in-site in molten iron by magnesium-based desulfurization, and bubble dispersed and disintegrated under the condition of mechanical stirring, thence to improve the efficiency of desulfurization by single blow grain magnesium .It has been proved by research of cold water model experiment that the bubble dispersion and disintegration can not only improve the desulphurization efficiency but also increase the utilization rate of magnesium. Obviously, the bubble dispersion and disintegration of magnesium vapor is the key problem in improving the desulphurization efficiency and increasing the utilization rate of magnesium. Thus the research focus on exploring the performance of bubble dispersion and disintegration on the base of refining process and gas-liquid mass transfer. According to the literature and cold water model experimental result basing on principle of similitude, the influencing factors and interaction of bubble dispersion and disintegration have been studied from the perspectives of physical and numerical simulation. The study would provide the theoretical and experimental data for the new method of desulfurization with in-situ mechanical stirring.

关键词： in-situ mechanical stirring method magnesium-based desulfurization bubble disintegration and dispersion injection refining water model

Study on Absorption Rate by Eccentric Mechanical Stirring in Gas Injection Refining for Iron and Steel Making

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Journal of Iron and Steel Research International 2011年第S2期18卷 166-171页

作者： masamichi Sano Nagoya University

In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable for high refining efficiency. Eccentric mechanical stirring with unidirectional impeller rotation was tested using a water model for pursuing better bubble disintegration and dispersion. Absorption rate are used to research on the influence law of the bubble dispersion and disintegration and gas-liquid absorption by the influence of, rotation mode, rotation speed and gas flow rate. Compared to the experimental results of absorption rate under eccentric stirring and centric stirring ,provide the scientific experimental and theoretical guidance for high-temperature experiment of hot metal desulfurization .According to experimental and theoretical analysis, this paper has studied various factors effecting on gas absorption process and volumetric mass transfer coefficient using the system of *** results show that:the volumetric mass transfer coefficient and absorption efficiency of CO2 can be increased under eccentric stirring mode, Because bubble disperse quickly with eccentric mechanical stirring, which results in promoting complete reaction between CO2 and NaOH, and improving the mass transfer coefficient and absorption. Volumetric mass transfer coefficient and efficiency of CO2 increase with the increasing rotation speed under the condition of eccentric stirring .But volumetric mass transfer coefficient and efficiency of CO2 decrease with the increasing rotation speed under the condition of centric stirring.

关键词： eccentric stirring bubble dispersion bubble disintegration volumetric mass transfer coefficient efficiency of CO2

Bubble behavior in cylindrical and square vessels under centric mechanical stirring

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Journal of Iron and Steel Research International 2021年第10期28卷 1243-1250页

作者： Kun Wang Yan Liu masamichi Sano Ting-an Zhang School of Metallurgy Northeastern UniversityShenyang110819LiaoningChina Department of Materials Processing Engineering Nagoya UniversityNagoya464-8601Japan

Water model experiments were carried out to investigate the bubble behavior in cylindrical and square vessels under centric mechanical *** bubble behavior in the square vessel was investigated in detail by using a high-speed camera to record the transient images of the *** image analysis software was used to obtain the bubble *** results showed that the centric mechanical stirring in the square vessel was suitable for breakage and dispersion of bubbles,but not suitable for that in the cylindrical *** the impeller blade length and impeller rotation speed was beneficial to disintegrate and disperse bubbles *** bubble diameter decreased with the increase in the Weber number and increased slightly with the increase in the modified Froude *** dimensionless correlation equation of bubble diameter was obtained by the dimensional analysis method.

关键词： Gas injection refining Mechanical stirring Mg desulfurization Bubble breakage Bubble dispersion Dimensional analysis

Contributions of distinct prefrontal neuron classes in reward processing

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Science China(Technological Sciences) 2014年第6期57卷 1257-1268页

作者： PAN XiaoChuan FAN HongWei WANG RuBin SAKAGAMI masamichi Institute for Cognitive Neurodynamics East China University of Science and Technology Brain Science Institute Tamagawa UniversityTamagawagakuen 6-1-1MachidaTokyo 194-8610Japan

The prefrontal cortex(PFC)is thought to be involved in higher order cognitive functions,such as in working memory,abstract categorization,and reward *** has been reported that two distinct neuron classes(putative pyramidal cells and interneurons)in the PFC played different functional roles in neural circuits involved in forming working memory and abstract ***,it remains elusive how the two types of neurons process reward information in the *** investigate this issue,the activity of single neurons was extracellularly recorded in the PFC of the monkey performing a reward predicting *** neurons were classified into putative pyramidal cells and interneurons,respectively,based on the waveforms of action *** the two types of neurons encoded reward information and discriminated two reward conditions(the preferred reward condition *** nonpreferred reward condition).However,the putative pyramidal neurons had better and more reliable discriminability than the putative ***,the pyramidal cells represented reward information in the preferred reward condition,but not in the nonpreferred reward condition by raising their firing rates relative to the baseline *** contrast,the interneurons encoded reward information in the nonpreferred reward condition,but not in the preferred reward condition by inhibiting their discharge rates relative to the baseline *** results suggested that the putative pyramidal cells and interneurons had complementary functions in reward *** findings may help to clarify individual functions of each type of neurons in PFC neuronal circuits involved in reward processing.

关键词： prefrontal cortex reward pyramidal neuron interneuron monkey single-unit activity

Vulnerable atherosclerotic plaque features:findings from coronary imaging

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Journal of Geriatric Cardiology 2021年第7期18卷 577-584页

作者： Osamu Kurihara masamichi Takano Yasushi Miyauchi Kyoichi Mizuno Wataru Shimizu Cardiovascular Center Chiba Hokusoh HospitalNippon Medical SchoolChibaJapan Mitsukoshi Health and Welfare Foundation TokyoJapan Division of Cardiology Nippon Medical SchoolTokyoJapan

Pathological studies have suggested that features of vulnerable atherosclerotic plaques likely to progress and lead to acute cardiovascular events have specific *** the progress of intravascular coronary imaging technology,some large prospective studies have detected features of vulnerable atherosclerotic plaques using these imaging ***,the rate of cardiovascular events,such as acute coronary syndrome,has been found to be considerably reduced in the limited follow-up period available in the statin ***,not all disrupted plaques lead to thrombus formation with clinical *** sub-occlusive or occlusive thrombus formation does not occur,a thrombus on a disrupted plaque will organize without any symptoms,forming a"healed plaque".Although vulnerable plaque detection using intracoronary imaging is focused on"thin-cap fibroatheroma"leading to plaque rupture,superficial plaque erosion is increasingly recognized;however,the underlying mechanism of thrombus formation on eroded plaques is not well *** of intravascular imaging,optical coherence tomography(OCT)has the highest image resolution and has enabled detailed characterization of the plaque in ***,we reviewed the status and limitations of intravascular imaging in terms of detecting vulnerable plaque through mainly OCT *** suggested that vulnerable plaque should be reconsidered in terms of eroded plaque and healed plaque and that both plaque and circulating blood should be assessed in greater detail accordingly.

关键词： coronary acute superficial

One-Stage Correction with Intra- and Extraatrial Rerouting of Anomalous Systemic and Pulmonary Venous Return and Intraventricular Repair of Double Outlet Right Ventricle in a Patient with Heterotaxy Syndrome

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Congenital Heart Disease 2022年第1期17卷 25-30页

作者： Helena Staehler Carina Hopfner masamichi Ono Jurgen Horer Department of Congenital and Pediatric Heart Surgery German Heart Center MunichTechnische Universitat MünchenDivision of Congenital and Pediatric Heart SurgeryUniversity Hospital of MunichLudwig-Maximilians-UniversitatMunichGermany Department of Pediatric Cardiology and Pediatric Intensive Care University Hospital of MunichLudwig-Maximilians-UniversitatMunichGermany

We report a very rare case of successful intracardiac correction in a patient with heterotaxy *** cardiac malformations included dextrocardia,double outlet right ventricle,pulmonary stenosis,interrupted inferior vena cava,hemiazygos continuation and total anomalous pulmonary venous ***-stage correction was *** atrial procedure consisted of intra-and extraatrial rerouting of the anomalous systemic and pulmonary venous *** hepatic veins were detached and diverted to the left atrium via an extracardiac *** correction of the double outlet right ventricle was accomplished by intraventricular redirection of the blood flow from the left ventricle to the *** right ventricular outflow was ultimately remodeled using a valved *** better perception of the complex morphology,a three-dimensional model was designed,using CT scan *** proved to be very useful for surgical planning,especially with regard to the intraatrial reconstruction of the systemic and pulmonary venous rerouting.

关键词： Heterotaxy syndrome anomalous systemic venous return anomalous pulmonary venous return azygos continuation double outlet right ventricle 3D modeling