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Phytochemical constituents,antioxidant and antibacterial activities of methanolic extract of Ardisia elliptica

Asian Pacific Journal of Tropical Biomedicine 2017年第6期7卷 569-576页

作者： Nazeh M.Al-Abd Zurainee Mohamed Nor marzida mansor Asdren Zajmi Mohd Shahnaz Hasan Fadzly Azhar Mustafa Kassim Department of Parasitology Faculty of MedicineUniversity of Malaya Faculty of Medicine and Health Sciences University of Aden Department of Anesthesiology Faculty of MedicineUniversity of Malaya Department of Diagnostic and Allied Health Sciences Faculty of Health and Life SciencesManagement and Science University Department of Chemistry Faculty of ScienceUniversity of Malaya

Objective:To investigate the antioxidant,antibacterial,and chemical ingredients of Ardisia elliptica(***) methanolic ***:The plant was extracted using *** and antioxidant activities were ***:The results showed that both fruit and leaf extract of *** have significant antibacterial activities against Gram-positive and Gram-negative *** extracts showed higher content of phenolic(71 ± 0.03 GAE/mg extract dry weight),in comparison to the leaf extracts(37 ± 0.05 GAE/mg extract dry weight).Flavonoid content,and Fe2+chelating activity of fruit extracts were higher than leaf *** percentage radical inhibition of fruit extract is found to be higher(70%) than that of leaf extract(60%).LCMS results indicated that the major compounds in the fruit extract were Gingerol,Aspidin,Kampherol,and Stercuresin,while the leaf extract contained Gingerol,Aspidin,Triangularin,and Salicyl acyl ***,the results of GCMS indicated that fruit extract contained these major compounds:Vitamin E Tocopherol,5-hepylresornicol,2-Nonylmalonic acid,5-pentadecylresornicol,and ***,leaf extract of *** contained these major compounds:Alpha Amyrenol,4,4,6,6a,6b,8,8a,9,10,11,12,12 a,14,14 a,14 b octadehydro-2H-picen-3-one,and Lonasterol,4-t-Butyl-2-[4-nitrophenyl] ***:The results provide evidence that fruit and leaf of *** extracts might indeed be used as a potential source of effective natural antimicrobial and antioxidant agents in pharmaceutical and food industries.

关键词： Ardisia elliptica Antioxidant capacity Total phenol content Gas chromatography/mass spectrometry Liquid chromatography/mass spectrometry

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Prevalence of filarial parasites in domestic and stray cats in Selangor State, Malaysia

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Asian Pacific Journal of Tropical Medicine 2015年第9期8卷 693-697页

作者： Nazeh M Al-Abd Zurainee Mohamed Nor Mustafa Kassim marzida mansor Abdulelah H.Al-Adhroey Romano Ngui Sinnadurai Sivanandam Department of Parasitology Faculty of Medicine University of Malaya Department of Anesthesiology Faculty of Medicine University of Malaya

Objective: To determine the prevalence of the filarial parasites, ie., Brugia malayi, Brugia pahangi(B. pahangi), Dirofilaria immitis and Dirofilaria repens(D. repens)in domestic and stray cats. Methods: A total of 170 blood sample were collected from domestic and stray cats and examined for i larial worm parasites in two localities, Pulau Carey and Bukit Gasing, Selangor State, Malaysia. Results: The overall prevalence of infection was 23.5%(40/170; 95% CI=17.4–30.6). Of this, 35%(14/40; 95% CI=22.1–50.5) and 50%(20/40; 95% CI=35.2–64.8) were positive for single B. pahangi and D. repens, respectively. The remaining of 15%(6/40; 95% CI=7.1–29.1) were positive for mixed B. pahangi and D. repens. In addition, 75% of the infected cats were domestic, and 25% were strays. No Brugia malayi and Dirofilaria immitis was detected. Eighty-four cats were captured at Pulau Carey, of which 35.7%(30/84) were infected. Among the cats determined to be infected, 93%(28/30; 95% CI=78.7–98.2) were domestic, and only 6.7%(2/30; 95% CI=19.0–21.3) were strays. Conversely, the number of infected cats was three times lower in Bukit Gasing than in Pulau Carey, and most of the cats were stray. Conclusions: B. pahangi and D. repens could be the major parasites underlying i lariasis in the study area. Adequate prophylactic plans should be administrated in the cat population in study area.

关键词： Filarial parasites Brugia Wuchereria Dirofilaria Cat Filariasis

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