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Investigation of the transcriptomic and metabolic changes associated with superficial scald physiology impaired by lovastatin and 1-methylcyclopropene in pear fruit(cv.“Blanquilla”)

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Horticulture Research 2020年第1期7卷 2229-2245页

作者： Jordi Giné-Bordonaba Nicola Busatto Christian Larrigaudière Violeta Lindo-García Gemma Echeverria Urska Vrhovsek Brian Farneti Franco Biasioli Concetta De Quattro marzia Rossato Massimo Delledonne Fabrizio Costa XaRTA-Postharvest Institute for Food and Agricultural Research and Technology(IRTA)Edifici FruitcentreParc Científic i Tecnològic Agroalimentari de Lleida25003 LleidaSpain Department of Genomics and Biology of Fruit Crops Research and Innovation CentreFondazione Edmund Machvia Mach 138010 San Michele all’AdigeTrentoItaly Department of Food Quality and Nutrition Research and Innovation CentreFondazione Edmund Machvia Mach 138010 San Michele all’AdigeTrentoItaly Department of Biotechnology University of VeronaStrada le Grazie 1537134 VeronaItaly Center Agriculture Food Environment University of Trentovia Mach 138010 San Michele all’AdigeTrentoItaly

To elucidate the physiology underlying the development of superficial scald in pears,susceptible“Blanquilla”fruit was treated with different compounds that either promoted(ethylene)or repressed(1-methylcyclopropene and lovastatin)the incidence of this disorder after 4 months of cold *** data show that scald was negligible for the fruit treated with 1-methylcyclopropene or lovastatin,but highly manifested in untreated(78%incidence)or ethylenetreated fruit(97%incidence).The comparison between the fruit metabolomic profile and transcriptome evidenced a distinct reprogramming associated with each *** all treated samples,cold storage led to an activation of a cold-acclimation-resistance mechanism,including the biosynthesis of very-long-chain fatty acids,which was especially evident in 1-methylcyclopropane-treated *** the treatments applied,only 1-methylcyclopropene inhibited ethylene production,hence supporting the involvement of this hormone in the development of ***,a common repression effect on the PPO gene combined with higher sorbitol content was found for both lovastatin and 1-methylcyclopropene-treated samples,suggesting also a non-ethylene-mediated process preventing the development of this *** results presented in this work represent a step forward to better understand the physiological mechanisms governing the etiology of superficial scald in pears.

关键词： superficial impaired hence

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Gastrointestinal tract injuries after thermal ablative therapies for hepatocellular carcinoma:A case report and review of the literature

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World Journal of Gastroenterology 2020年第35期26卷 5375-5386页

作者： Teresa marzia Rogger Andrea Michielan Sandro Sferrazza Cecilia Pravadelli Luisa Moser Flora Agugiaro Giovanni Vettori Sonia Seligmann Elettra Merola Marcello Maida Francesco Antonio Ciarleglio Alberto Brolese Giovanni de Pretis Department of Surgery Gastroenterology and Digestive Endoscopy UnitSanta Chiara HospitalTrento 38122Italy Gastroenterology and Endoscopy Unit S.Elia-Raimondi HospitalCaltanissettaCaltanissetta 93100Italy Department of Surgery Hepato-biliary Surgery UnitSanta Chiara HospitalTrento 38122Italy

BACKGROUND Radiofrequency ablation(RFA)and microwave ablation(MWA)represent the standard of care for patients with early hepatocellular carcinoma(HCC)who are unfit for *** incidence of reported adverse events is low,ranging from 2.4%to 13.1%for RFA and from 2.6%to 7.5%for *** tract(GIT)injury is even more infrequent(0.11%),but usually requires surgery with an unfavourable *** to its low incidence and the retrospective nature of the studies,the literature reporting this feared complication is heterogeneous and in many cases lacks information on tumour characteristics,comorbidities and treatment *** SUMMARY A 77-year-old man who had undergone extended right hepatectomy for HCC was diagnosed with early disease recurrence with a small nodule compatible with HCC in the Sg4b segment of the liver with a subcapsular *** was treated with percutaneous RFA and a few week later he was urgently admitted to the Surgery ward for abdominal pain and fever.A subcutaneous abscess was diagnosed and treated by percutaneous drainage.A fistulous tract was then documented by the passage of contrast material from the gastric antrum to the abdominal *** oesophagogastroduodenoscopy confirmed a circular wall defect at the lesser curvature of gastric antrum, leading directly to the purulentabdominal collection. An over-the-scope clip (OTSC) was used to successfullyclose the defectCONCLUSIONThis is the first reported case of RFA-related GIT injury to have been successfullytreated with an OTSC, which highlights the role of this endoscopic treatment forthe management of this complication.

关键词： Gastrointestinal tract Radiofrequency ablation Hepatocellular carcinoma Complications Endoscopy Over-the-scope clip Case report

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Meta-analysis of CO_(2) conversion,energy efficiency,and other performance data of plasma-catalysis reactors with the open access PIONEER database

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Journal of Energy Chemistry 2023年第11期86卷 318-342,I0007页

作者： Antoine Salden Maik Budde Carolina A.Garcia-Soto Omar Biondo Jairo Barauna marzia Faedda Beatrice Musig ChloéFromentin Minh Nguyen-Quang Harry Philpott Golshid Hasrack Domenico Aceto Yuxiang Cai Federico Azzolina Jury Annemie Bogaerts Patrick Da Costa Richard Engeln María Elena Gálvez Timo Gans Tomas Garcia Vasco Guerra Carlos Henriques Monika Motak Maria Victoria Navarro Vasile I.Parvulescu Gerard Van Rooij Bogdan Samojeden Ana Sobota Paolo Tosi Xin Tu Olivier Guaitella Department of Physics University of Trento38100 PovoItaly Department of Applied Physics and Science Education Eindhoven University of Technology5600 MB EindhovenThe Netherlands Instituto de Plasmas e Fusão Nuclear Instituto Superior TécnicoUniversidade de Lisboa1049-001 LisboaPortugal LPP CNRSÉcole PolytechniqueSorbonne UniversitéUniversitéParis-SaclayIP-Paris 91128 PalaiseauFrance Department of Organic Chemistry Biochemistry and CatalysisUniversity of BucharestBucharestRomania Research Group PLASMANT Department of ChemistryUniversity of AntwerpUniversiteitsplein 1Wilrijk B-2610Belgium DIFFER 5612AJ EindhovenThe Netherlands Instituto de Carboquímica ICB-CSIC Zaragoza 50018Spain Faculty of Energy and Fuels AGH University of KrakowKrakowPoland Institut Jean le Rond d’Alembert CNRS UMR 7190-Sorbonne UniversitéSaint-Cyr l’Ecole 78210France Laboratoire Catalyse et Spectrochimie(LCS) CNRS-ENSICAEN-Universitéde Caen6 boulevard du Maréchal-Juin14000 CaenFrance CQE Centro de Química EstruturalInstituto Superior TécnicoUniversidade de LisboaAv.Rovisco Pais1049-001 LisboaPortugal School of Physical Sciences and National Centre for Plasma Science and Technology Faculty of Science and HealthDublin City UniversityDublinIreland ASML De Run 65015504 DR VeldhovenThe Netherlands Faculty of Science and Engineering Maastricht University6229 GS MaastrichtThe Netherlands CNR Istituto per la Scienza e Tecnologia dei Plasmi(ISTP)Italy Department of Electrical Engineering and Electronics University of LiverpoolLiverpool L693GJUK

This paper brings the comparison of performances of CO_(2)conversion by plasma and plasma-assisted catalysis based on the data collected from literature in this field,organised in an open access online *** tool is open to all users to carry out their own analyses,but also to contributors who wish to add their data to the database in order to improve the relevance of the comparisons made,and ultimately to improve the efficiency of CO_(2)conversion by *** creation of this database and database user interface is motivated by the fact that plasma-catalysis is a fast-growing field for all CO_(2)conversion processes,be it methanation,dry reforming of methane,methanolisation,or *** a result of this rapid increase,there is a need for a set of standard procedures to rigorously compare performances of different ***,this is currently not possible because the fundamental mechanisms of plasma-catalysis are still too poorly understood to define these standard *** however,the accumulated data within the CO_(2)plasma-catalysis community has become large enough to warrant so-called“big data”studies more familiar in the fields of medicine and the social *** enable comparisons between multiple data sets and make future research more effective,this work proposes the first database on CO_(2)conversion performances by plasma-catalysis open to the whole *** database has been initiated in the framework of a H_(2)0_(2)0 European project and is called the“PIONEER Data Base”.The database gathers a large amount of CO_(2)conversion performance data such as conversion rate,energy efficiency,and selectivity for numerous plasma sources coupled with or without a *** data set is associated with metadata describing the gas mixture,the plasma source,the nature of the catalyst,and the form of coupling with the *** the database itself,a data extraction tool with direct visualisation features or advance

关键词： Open-access database on plasma-catalysis experiment CO_(2) conversion Plasma-catalysis Carbon capture and utilisation(CCU) Energy efficiency Specific energy input Dielectric barrier discharge Packed bed reactor Methanation Dry reforming of methane

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Nutraceutical Properties of Meat from Grazing Podolian Young Bulls

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Food and Nutrition Sciences 2014年第7期5卷 618-625页

作者： Rosaria Marino marzia Albenzio Antonella della Malva Ada Braghieri Agostino Sevi Department of the Sciences of Agriculture Food and Environment University of Foggia Foggia Italy

The effect of rearing system (pasture with supplementation 15% crude protein OUT15 vs indoorIND) on meat nutritional and nutraceutical properties was evaluated in twenty Podolian young bulls. Meat quality characteristics were measured on three different muscles (Longissimus dorsi, LD, Semimembranosus, SM, Semitendinosus, ST), vacuum-packaged and chilled stored at 2℃ - 4℃ for 15 days. No differences were found on chemical composition in meat from animals reared with different rearing system. Pasture with supplementation produced an improvement in fatty acid composition with a higher polyunsaturated fatty acid percentage, particularly, conjugated linoleic acids (CLA) and very long chain ω3 PUFA, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Meat from young bulls reared at pasture with supplementation showed in all examined muscles the highest α-tocopherol content compared with meat from IND group. On the other hand, malondialdehyde content was not affected by the feeding treatment.

关键词： Podolian Cattle Fatty Acid PUFA Nutraceutical Properties EPA DHA

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Effectiveness and safety of antithrombotic strategies in elderly patients with acute myocardial infarction

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World Journal of Cardiology 2020年第11期12卷 513-525页

作者： Elisa Rondano marzia Bertolazzi Alessandro Galluzzo Ludovica Maltese Paolo Caccianotti Sergio Macciò Stefano Mazza Maria Virginia Di Ruocco Serena Favretto Eraldo Occhetta Francesco Rametta Cardiology Department St.Andrea HospitalVercelli 13100Italy

BACKGROUND Elderly patients represent a rapidly growing part of the population more susceptible to acute coronary syndromes and their ***,literature evidence is lacking in this clinical *** To describe the clinical features,in-hospital management and outcomes of“elderly”patients with myocardial infarction treated with antiplatelet and/or anticoagulation *** This study was a retrospective analysis of all consecutive patients older than 80 years admitted to the Division of Cardiology of *** Hospital of Vercelli from January 2018 to December 2018 due to ST-elevation myocardial infarction(STEMI)or non-ST elevation myocardial infarction(NSTEMI).Clinical and laboratory data were collected for each patient,as well as the prevalence of previous or in-hospital atrial fibrillation(AF).In-hospital management,consisting of an invasive or conservative strategy,and the anti-thrombotic therapy used are *** evaluated at 1 year follow-up included an efficacy ischemic endpoint and a safety bleeding *** Of the 105 patients enrolled(mean age 83.9±3.6 years,52.3%males),68(64.8%)were admitted due to NSTEMI and 37(35.2%)due to *** the STEMI patients,34(91.9%)underwent coronary angiography and all of them were treated with percutaneous coronary intervention(PCI);among the NSTEMI patients,42(61.8%)were assigned to an invasive strategy and 16(38.1%)of them underwent a *** significant difference between the groups was found concerning the prevalence of previous or in-hospital de-novo AF.10.5%of the whole population received triple antithrombotic therapy and 9.5%single antiplatelet therapy plus oral anticoagulation(OAC),with no significant difference between the subgroups,although a higher number of STEMI patients received dual antiplatelet therapy without OAC as compared with NSTEMI patients.A low rate of in-hospital death(5.7%)and 1-year cardiovascular death(3.3%)was ***(7.8%)patients experienced

关键词： Antiplatelet therapy Anticoagulant therapy Elderly patients Safety Acute myocardial infarction

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Quality of Soppressata salami from Pugliese Pigs as Affected by Rearing System

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Food and Nutrition Sciences 2014年第7期5卷 626-634页

作者： marzia Albenzio Antonella Santillo Rosaria Marino Francesca d’ Angelo Mariangela Caroprese Agostino Sevi Department of the Sciences of Agriculture Food and Environment University of Foggia Foggia Italy

Twenty four male pigs were assigned to two groups of 12 each during the last fattening phase: one group was reared outdoor (OUT group) and fed on natural pasture, while the other group was reared indoor (IND group) and fed on commercial feedstuff. Meat was processed into Soppressata salami according to traditional protocol. Meat and Soppressata salami were analyzed for nutritional, textural and color parameters. Meat and Soppressata salami showed significantly higher proportion of unsaturated fatty acids in OUT than that in IND group. Ameliorated nutritional indexes in terms of n-6/n-3 ratio, and thrombogenic index were found both in meat and Soppressata salami in OUT group. Texture Profile Analysis showed lower values in the tested samples from OUT thanINDgroup. Lightness, redness, and chroma parameters were higher both in meat and Soppressata salami in OUT group;whereas hue parameter was lower in Soppressata salami from OUT pigs. Outdoor rearing improved fatty acid profile, nutritional indexes, color and mechanical properties of pork meat thanks to natural pasture, greater space allowance and physical exercise of animal during the fattening phase. Meat features strictly affected the quality of the Soppressata salami produced by using traditional protocol.

关键词： Pig Meat Soppressata salami Nutritional Properties Textural Properties Meat Color

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Biological and Nutritional Aspects of Human Milk in Feeding of Preterm Infants

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Food and Nutrition Sciences 2012年第12期3卷 1682-1687页

作者： marzia Giribaldi Laura Cavallarin Cristina Baro Paola Di Nicola Alessandra Coscia Enrico Bertino CNR—Institute of Sciences of Food Production Grugliasco Italy Neonatal Unit Department of Pediatric and Adolescence Science University of Turin Turin Italy.

Breastfeeding and human milk are the normative standards for feeding and nutrition of both term and pre-term infants. Fresh mother’s own milk is recognized as the optimal choice for feeding all newborns, including preterm and very low birth weight infants. Evidence documents short and long-term metabolic, immunologic and neurodevelopmental advantages of breastfeeding when compared to formula. Moreover, benefits of breastfeeding on psychological and relational aspects have to be considered. Currently, human milk supplementation is usually performed to meet the specific nutritional requirements of preterm infants. When mother’s milk is unavailable or in short supply, donor milk represents the best alternative, although some nutritional elements are inactivated by the necessary pasteurization process. Aim of this review is to briefly summarize the main biological and nutritional factors that contribute to the beneficial effects of human milk feeding for preterm infants.

关键词： Human Milk Preterm Infants Fortification Donor Milk

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A Novel Low Temperature Synthesis of KNN Nanoparticles by Facile Wet Chemical Method

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Materials Sciences and Applications 2017年第3期8卷 247-257页

作者： Rashmi Rani Seema Sharma marzia Quaglio Radheshyam Rai Stefano Bianco Diego Pugliese Candido Fabrizio Pirri Ferroelectric Research Laboratory Department of Physics A. N. College Patna India Center for Space Human Robotics (CSHR) Instituto Italiano di Tecnologia (IIT) Torino Italy Department of Applied Science and Technology (DISAT) Politecnico di Torino Torino Italy School of Physics and Materials Science Shoolini University Solan India

Sodium potassium niobate (KNN) (K0.5Na0.5NbO3) nanopowder with a mean particle size of about 20 - 30 nm was synthesized by wet chemical route using Nb2O5 as Nb source. A solution of K, Na and Nb cations was prepared, which resulted in a clear gel after the thermal treatment. Phase analysis, microstructure and morphology of the powder were determined by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR) and Field Emission Scanning Electron Microscopy (FESEM). The obtained gel was first analyzed by Thermo Gravimetric Analyzer (TGA) and Differential Scanning Calorimetry (DSC), and then calcined at different temperatures of 400℃, 500℃, 600℃ and 700℃. The X-Ray Diffraction (XRD) patterns of the synthesized samples confirmed the formation of the orthorhombic crystal phase of K0.5Na0.5NbO3 at 500?C, a temperature significantly lower than that typically used in the conventional mixed oxide route. The process developed in this work is convenient to realize the mass production of KNN nanopowders at low cost and suitable for various industrial applications.

关键词： KNN Nano-Powder Sol-Gel Method Perovskite Phase Low Temperature Sintering Ceramic Processing

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Preliminary Phytochemical Investigation and Antiproliferative Activity of Daphne altaica Pall.

Preliminary Phytochemical Investigation and Antiproliferativ...

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第十四届全国中药和天然药物学术研讨会

作者： Murat Kizaibek marzia Daniar Sandugash Bahytjan Didar Bahytjan Panar Sawutbai Ryza Kasymkan Traditional Kazakh Medicine Research Institute of Hi Kazakh Autonomous Prefecture Xinjiang Medical University China Pharmaceutical University

＜正＞Daphne altaica Pall.（Thymelaeaceae）is a medicinal plant that has long been used to treat cancer and respiratory ailments in Traditional Kazakh *** present work was conducted to investigate the preliminary phytochemical studies and antiproliferative activities on the stembarks of *** Pall..Six extracts of different polarity,namely aqueous,

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Burden of Cardiometabolic Risk Factors on Cerebrovascular Events in a Southern Italian Population

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World Journal of Cardiovascular Diseases 2021年第2期11卷 145-152页

作者： Vincenzo Capuano Federica Marchese Rocco Capuano Anna Grazia Iannone Norman Lamaida Ernesto Capuano Raffaella Sica marzia Manilia Eduardo Capuano Operating Unit of Cardiology and UTIC Mercato S. Severino Hospital Azienda Ospedaliera Universitaria di Salerno Salerno Italy

Background: Stroke is the second leading cause of death in the world and the third due to disability. However, there are few data available that identify the risk factors associated with it and their weight in different populations (population risk). Aim: Contribute to the knowledge of burden risk factors in stroke in a large cohort of Southern Italy. Methods: The data refer to a randomized Campania cohort of 1200 subjects (35 - 74 years) enrolled in 2008-09. Ten years later (2018-19) they were re-evaluated. We analyzed data from 32 patients who reported a cerebrovascular event (stroke or TIA) with the event-free group of subjects (804 subjects: 378 men and 426 women). We evaluated: absolute risk, Odds Ratio (OR), Additional Risk (AR), Risk Attributable to the Population (PAR) and, finally, the Population Attributable risk Fraction (FAP). Results: In the comparison between the two groups (patients with events and patients without events) the risk factors with statistically significant differences were: age, Systolic Blood Pressure (SBP), BMI, cholesterol, triglycerides, glycemia and hyperinsulinemia. The ORs with the greatest impact were: blood glucose (5.1), BMI (3.3) and BPS (2.9). Linear regression analysis identified Glycemia and BMI as the only independent variables. The FAPs with the

关键词： Cerebrovascular Risk Factors Southern Italy Risk Attributable to the Popula-tion

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