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Unveiling the silent crisis:global burden of suicide‑related deaths among children aged 10–14 years

World Journal of Pediatrics 2024年第4期20卷 371-391页

作者： Irmina Maria michalek Pawel Koczkodaj marzena michalek Florentino Luciano Caetano dos Santos Department of Cancer Epidemiology and Primary Prevention Maria Sklodowska-Curie National Research Institute of Oncologyul.Wawelska 15 BWarsawPoland Private Psychiatric Practice-marzena michalek MDSiedlcePoland Harvard Business School Harvard UniversityBostonMAUSA

Background The rise in suicides among children aged 10–14 years demands urgent attention *** study aims to assess the global burden of suicide-related deaths in this age group from 1990 to 2019,considering factors such as sex,geography,and sociodemographics,to inform prevention strategies and *** The data from Global Burden of Disease 2019,encompassing 204 countries and territories,were analyzed to investigate deaths and years of life lost(YLLs)due to suicide among children aged 10–14 *** analyses,including mortality rates,YLLs,and the sociodemographic index(SDI),were conducted using standardized *** In 2019,a total of 8327[95%uncertainty interval(UI)=7073–9685]children aged 10–14 years died globally due to suicide,with a mortality rate of 1.30(95%UI=1.10–1.51)per 100,*** rates varied across countries/territories ranging between 0.05(95%UI=0.02–0.10)in South Africa and 7.49(95%UI=5.13–10.57)in *** contribution of suicide-related deaths to all-cause mortality ranged from 0.07%(95%UI=0.04%–0.15%)in South Africa to 33.02%(95%UI=24.36%–41.53%)in ***,there were approximately 636,196(95%UI=540,383–740,009)YLLs due to suicide,with a rate of 99.07(95%UI=84.15–115.23)per 100,*** association between SDI and suicide-related deaths was evident,with higher contributions observed in countries with higher *** This study reveals a concerning global burden of suicide-related deaths among children aged 10–14 *** progress in reducing mortality rates,suicide remains a significant *** overall rates have declined,the percentage of deaths caused by suicide in this age group is increasing.

关键词： Early adolescent Global Burden of Disease Incidence Suicide Years of life lost

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A Comparison of Experimental and Numerical Studies Performed on a Low-Pressure Turbine Blade Cascade at High-Speed Conditions, Low Reynolds Numbers and Various Turbulence Intensities

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Journal of Thermal Science 2013年第5期22卷 413-423页

作者： Jan michalek Petr Straka VZLU - Aerospace Research and Test Establishment Beranovych 130 19500 PragueCzech Republic

This paper focuses on a comparison of experimental and numerical investigations performed on a low-pressure mid-loaded turbine blade at operating conditions comprised of a wide range of Math numbers （from 0.5 - 1.1）, Reynolds numbers （from 0.4e＋5 - 3.0e＋5）, flow incidence （-15 - 15 degrees） and three levels of free-stream tur- bulence intensities （2, 5 and 10%）. The experimental part of the work was performed in a high-speed linear cas- cade wind tunnel. The increased levels of turbulence were achieved by a passive grid placed at the cascade inlet. A two-dimensional flow field at the center of the blade was traversed pitch-wise upstream and downstream the cascade by means of a five-bole probe and a needle pressure probe, respectively. The blade loading was measured using the surface pressure taps evenly deployed at the blade mid-span along the suction and the pressure side. The inlet turbulence was investigated using the constant temperature anemometer technique with a dual sensor probe. Experimentally evaluated values of turbulent kinetic energy and its dissipation rate were then used as inputs for the numerical simulations. An in-house code based on a system of the Favre-averaged Navier-Stokes equation closed by a two-equation k-co turbulence model was adopted for the predictions. The code utilizes an algebraic model of bypass transition valid both for attached as for separated flows taking in account the effect of free-stream turbulence and pressure gradient. The resulting comparison was carried out in terms of the kinetic en- ergy loss coefficient, distributions of downstream wakes and blade velocity. Additionally a flow visualization was performed by means of the Schlieren technique in order to provide a further understanding of the studied phe- nomena. A few selected cases with a particular interest in the attached and separated flow transition are compared and discussed.

关键词： low pressure turbine high-speed flow low Reynolds number flow separation transition RANS

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Requirements and characteristics of a preservation quality information management system

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Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第11期11卷 923-926页

作者： Gabrielle V.michalek Carnegie Mellon University Libraries

1 Introduction The proliferation of digital materials has changed not only how information is presented but also how people expect information to be available. People want access to all forms of information,from simpl... 详细信息

关键词：质量信息管理系统保存求和多媒体

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Computational Decision Support System for ADHD Identification

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International Journal of Automation and computing 2021年第2期18卷 233-255页

作者： Senuri De Silva Sanuwani Dayarathna Gangani Ariyarathne Dulani Meedeniya Sampath Jayarathna Anne M.P.michalek Department of Computer Science and Engineering University of MoratuwaMoratuwa 10400Sri Lanka Department of Computer Science College of ScienceOld Dominion UniversityNorfolk 23529USA Department of Communication Disorders and Special Education Old Dominion UniversityNorfolk 23529USA

Attention deficit/hyperactivity disorder(ADHD)is a common disorder among *** often prevails into adulthood,unless proper treatments are facilitated to engage self-regulatory ***,there is a need for effective and reliable mechanisms for the early identification of *** paper presents a decision support system for the ADHD identification *** proposed system uses both functional magnetic resonance imaging(fMRI)data and eye movement *** classification processes contain enhanced pipelines,and consist of pre-processing,feature extraction,and feature selection *** data are processed by extracting seed-based correlation features in default mode network(DMN)and eye movement data using aggregated features of fixations and *** the classification using eye movement data,an ensemble model is obtained with 81%overall *** the fMRI classification,a convolutional neural network(CNN)is used with 82%accuracy for the ADHD *** ensemble models are proved for overfitting avoidance.

关键词： Attention deficit/hyperactivity disorder(ADHD) functional magnetic resonance imaging(fMRI) eye movement data seed-based correlation ensembled model convolutional neural network(CNN) default mode network(DMN) saccades fixations ADHD-Care decision support system(DDS)

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曲轴硬化新工艺

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拖拉机与农用运输车 1982年第5期 31-32页

作者： Hans michalek ,牛士宗

众所周知,曲轴圆角硬化可在不改变设计的情况下,提高曲轴的疲劳寿命。实用的处理方法主要是常规的气体氮化、盐浴氮碳共渗(软氮化)和圆角感应淬火。可是,这些方法都有一些副作用,因而效果受到了影响。理想的曲轴表面处理,包括圆角硬化... 详细信息

众所周知,曲轴圆角硬化可在不改变设计的情况下,提高曲轴的疲劳寿命。实用的处理方法主要是常规的气体氮化、盐浴氮碳共渗(软氮化)和圆角感应淬火。可是,这些方法都有一些副作用,因而效果受到了影响。理想的曲轴表面处理,包括圆角硬化在内,应是能在被处理的表层呈现硬度梯度的方法,例如感应淬火,这样可无需再淬火便

关键词：碳氧共渗圆角硬度梯度盐浴氮化感应淬火感应加热淬火曲轴传动轴

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牙龈卟啉单胞菌对破骨细胞前体调节作用的小鼠体内研究

牙龈卟啉单胞菌对破骨细胞前体调节作用的小鼠体内研究

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第十一次全国牙周病学学术会议

作者：蔡霞 Jenny Katz Suzanne michalek 张平 Department of Pediatric Dentistry University of Alabama at Birmingham 浙江大学医学院附属口腔医院牙周科 Department of Microbiology University of Alabama at Birmingham

目的:破骨细胞活力亢进是牙周炎病理性骨吸收的主要特点。但是破骨细胞前体(osteoclast precursors,OCP)对牙周感染的反应目前还不清楚。本研究通过在小鼠体内研究牙周致病菌牙龈卟啉单胞菌(Porphyromonasgingivalis,Pg)感染对于OCP的... 详细信息

目的:破骨细胞活力亢进是牙周炎病理性骨吸收的主要特点。但是破骨细胞前体(osteoclast precursors,OCP)对牙周感染的反应目前还不清楚。本研究通过在小鼠体内研究牙周致病菌牙龈卟啉单胞菌(Porphyromonasgingivalis,Pg)感染对于OCP的调节作用。方法:在C57BL/6野生鼠头盖骨皮下注射Pg (1 x 10cfu)or PBS,每日一次。在注射第3天或第7天,分离小鼠骨髓以及脾细胞,通过流式细胞术分析OCP表面分子的表达。分离小鼠头盖骨进行组织学分析以及炎性因子基因的表达。结果:在实验第7天,与空白对照组相比,Pg感染导致小鼠头盖骨显著的炎性浸润以及破骨细胞形成的增加。此外,来自Pg感染小鼠的骨髓细胞以及脾细胞进行体外破骨细胞培养,具有更高的破骨细胞分化潜能。Pg感染第7天,骨髓细胞以及脾细胞中CD11bc-fmsRANKOCP数量明显增加。Pg感染小鼠的脾细胞中CD11bc-fmRANKOCP数量显著增加。RT-PCR结果显示与空白对照组相比,Pg感染小鼠的头盖骨RANKL,IL-1band TNF-am RNA表达显著增加。结论:Pg感染能够增加OCP库以及OCP的破骨潜能,这可能与感染部位的破骨活性增加有关。

关键词：牙龈卟啉单胞菌破骨细胞前体破骨细胞形成 c-fms RANK

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作为城市景观的阿尔卑斯——克里斯坦·施密德访谈

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世界建筑 2007年第4期 23-25页

作者：彼得.米夏勒克李菁克里斯坦.施密德瑞士意大利语区高等专业学院苏黎世ETH建筑学院

在《瑞士—城市的图景》（Switzerland-an urban portrait）一书中,ETH巴塞尔工作室（Studio Basel）对瑞士不同地区的城市化现象及其未来的发展潜能做出了分析。研究结果对阿尔卑斯山地区现有的经济状态有所质疑,并提出了新型的基本解... 详细信息

在《瑞士—城市的图景》（Switzerland-an urban portrait）一书中,ETH巴塞尔工作室（Studio Basel）对瑞士不同地区的城市化现象及其未来的发展潜能做出了分析。研究结果对阿尔卑斯山地区现有的经济状态有所质疑,并提出了新型的基本解决方案。克里斯坦·施密德是一位地理学者,同时也是ETH巴塞尔工作室的科研人员,他对格劳宾登外围村镇的复杂状况有自己独到的见解。

关键词：阿尔卑斯城市景观科研人员工作室巴塞尔城市化基本解瑞士

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